Download PDF Myotubular myopathy is a severe genetic disease that leads to muscle paralysis from birth and results in death before two years of age. Although no treatment currently exists, researchers from the University of Geneva (UNIGE), Switzerland, – working in collaboration with the University of Strasbourg, France, – have identified a molecule that not […]Continue Reading ...
Download PDF Credit: Ravi Kant et al. A class of cells that defends the body against invaders also triggers obsessive-compulsive behaviour that appears in autoimmune disorders such as multiple sclerosis (MS), a new study from the Indian Institute of Science (IISc) has found. Autoimmune disorders, in which the body’s immune system goes rogue and attacks […]Continue Reading ...
Download PDF Researchers have found that a protein in the cell membranes of sperm plays a key role in how they find their way to eggs. The PMCA protein may also help explain how egg cells only interact with sperm from the same species. PMCA may even be a target of drug discovery. Sperm are […]Continue Reading ...
Download PDF SAN DIEGO, Nov. 9, 2018 /PRNewswire/ — Mirati Therapeutics, Inc. (NASDAQ: MRTX), a clinical-stage targeted oncology company, announced data from the ongoing Phase 2 clinical trial of mocetinostat in combination with durvalumab (IMFINZI®) in non-small cell lung cancer (NSCLC) patients at the Society for Immunotherapy of Cancer (SITC) 33rd Annual Meeting in Washington, […]Continue Reading ...
Download PDF After a prophylactic double mastectomy in 2015, Tina Harrison discovered that she did, indeed, have breast cancer–it just hadn’t been detected. Harrison, of Pinckney, Mich., correctly predicted the cancer–it ran in her family–but she didn’t anticipate her ongoing pain and loss of shoulder function after reconstructive surgery. Harrison isn’t alone, said David Lipps, […]Continue Reading ...
Download PDF Nabriva Therapeutics Completes Submission of New Drug Application to U.S. Food and Drug Administration for Intravenous Contepo to Treat Complicated Urinary Tract Infections DUBLIN, Ireland, Nov. 01, 2018 (GLOBE NEWSWIRE) — Nabriva Therapeutics plc (NASDAQ: NBRV), a clinical-stage biopharmaceutical company engaged in the research and development of innovative anti-infective agents to treat serious […]Continue Reading ...
Download PDF People who are bullied at work or experience violence at work are at higher risk of heart and brain blood vessel problems, including heart attacks and stroke, according to the largest prospective study to investigate the link, which is published in the European Heart Journal today (Monday). Although the study is observational and, […]Continue Reading ...
Download PDF A woman wears this soft and flexible groundbreaking new sensor, developed by the Rogers Research Group at Northwestern University, which uses measurements of temperature and heat transfer to non-invasively tell if and how much fluid is flowing through a shunt in a hydrocephalus patient. In the study, the skin sensor allowed hydrocephalus patients […]Continue Reading ...
Download PDF Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system. It is the first time that cancer-associated fibroblasts within solid tumors – healthy cells that are tricked into protecting the cancer […]Continue Reading ...
Download PDF Parents who decline to get their child vaccinated against the flu may be exposed to a limited range of information, a new national poll suggests. And depending on which sources parents turn to the most, inaccurate information may influence their decision about flu vaccine for their child. Annual flu vaccination is recommended for […]Continue Reading ...
Download PDF (HealthDay)—Rare but serious genital infections, as well as one death, have been reported in some patients taking a certain class of type 2 diabetes medicine, the U.S. Food and Drug Administration says. As a result, the FDA has ordered a new warning about this risk to be added to the prescribing information and […]Continue Reading ...
Download PDF In 2013, renowned Boston Children’s Hospital pain researcher Clifford Woolf, MB, BCh, PhD, and chemist Kai Johnsson, PhD, his fellow co-founder at Quartet Medicine, believed they held the key to non-narcotic pain relief. Woolf had shown that tetrahydrobioptrin — a protein also known as BH4 — is a primary natural modulator of neuropathic […]Continue Reading ...
Download PDF Pain medication such as oxycodone often helps cancer patients deal with intense pain after treatment, but it also can lead to abuse. Credit: Steve Heal/Shutterstock.com The availability of life-prolonging treatments such as hormonal therapies and other targeted chemotherapy has led to a sharp decline in breast cancer deaths in the United States. But […]Continue Reading ...
Download PDF WEDNESDAY, Nov. 14, 2018 — For patients with prediabetes who are randomly assigned to interventions, changes in risk indicators of metabolic syndrome (MetS) severity are associated with the risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), according to a study published in the November issue of Diabetes Care. Mark D. […]Continue Reading ...
Download PDF Alcohol advertisements on social media sites such as Facebook can increase young adults’ desire to drink if the ads contain pro-drinking comments from users. That’s according to new research in the current issue of the Journal of Studies on Alcohol and Drugs. Social media users who view alcohol ads are also more likely […]Continue Reading ...
- Researchers identify molecule to fight myotubular myopathy
- Immune cells trigger OCD-like behaviour in multiple sclerosis, study finds
- Scientists equip new virus that kills carcinoma cells with protein
- Protein in cell membranes of sperm plays key role in finding their way to eggs
- Parents who decline flu vaccination for their child may be exposed to limited information
- Mirati Presents Data From Ongoing Phase 2 Clinical Trial Of Mocetinostat In Combination With Durvalumab At The SITC 33rd Annual Meeting
- FDA warns of common diabetes meds’ link to dangerous genital infection
- New methods for preserving shoulder function, quality of life in breast cancer patients
- Surprising discovery about BH4 may rekindle interest in once-promising pathway
- Nabriva Therapeutics Completes Submission of New Drug Application to U.S. Food and Drug Administration for Intravenous Contepo to Treat Complicated Urinary Tract Infections
- Beating breast cancer only to die of opioid use – a sad Appalachian story
- Workplace bullying or violence linked to higher risk of cardiovascular problems
- Changes in Risk Indicators of MetS Severity Tied to T2DM Risk
- ‘Game-changing’ skin sensor could improve life for a million hydrocephalus patients
- Alcohol ads on social media sites with pro-drinking comments increase desire to drink
- Neural networks could replace marker genes in RNA sequencing
- Obese adolescents feel less food enjoyment than those with normal weight, study reveals
- Goodbye ‘Gluten-Free’? Celiac Disease Vaccine May Make It Possible
- Skin ages when the main cells in the dermis lose their identity and function
- Rainforest vine compound makes pancreatic cancer cells susceptible to nutrient starvation