Breaking News
October 15, 2018 - Innovative brain tumor operation set to tailor to patients’ needs
October 15, 2018 - Findings offer new insight into early changes that occur during AD pathology
October 15, 2018 - Neurons regulating reproductive hormone release have different activity in epileptic mice
October 15, 2018 - More parents are concerned about taking babies swimming in public pools
October 15, 2018 - Health Tip: Know the Risk Factors for Lower Back Pain
October 15, 2018 - Study shows cigarillo flavors enhanced by high-intensity sweeteners
October 15, 2018 - Study traces hospital-acquired bloodstream infections to patients’ own bodies | News Center
October 15, 2018 - Abnormal vision in childhood can affect development of brain areas responsible for attention
October 15, 2018 - Color-changing contact lens could help doctors to monitor eye disease medications
October 15, 2018 - Tobacco heating products cause less staining to teeth than conventional cigarettes
October 15, 2018 - Young adults who are obese can expect to lose up to 10 years in life expectancy
October 15, 2018 - Scientists uncover how proteins meet on the cell membrane
October 15, 2018 - Affordable housing with supportive social services for senior citizens can reduce hospital use
October 15, 2018 - Following a Tissue Sample
October 15, 2018 - Prisoners need drug and alcohol treatments but AA programs aren’t the answer
October 15, 2018 - Andrea Califano and Jordan Orange Elected to National Academy of Medicine
October 15, 2018 - The impending risk of African Swine Fever Virus
October 15, 2018 - Breastfeeding reduces the number of antibiotic-resistant bacteria in infant gut
October 15, 2018 - Researchers develop comprehensive molecular atlas of postnatal mouse heart development
October 15, 2018 - ObsEva SA Presents Clinical Data from Phase III IMPLANT 2 Trial of Nolasiban in IVF at the American Society of Reproductive Medicine (ASRM) Annual Meeting
October 15, 2018 - Engineering teratoma-derived fibroblasts to enhance osteogenesis
October 15, 2018 - Lab study shows effectiveness of potential therapy for treatment-resistant hypothyroidism
October 15, 2018 - JCU study firms up association between diet and depression
October 15, 2018 - Researchers to study the use of CRISPR on human liver on-a-chip platform
October 15, 2018 - Sub-concussive impacts not associated with decline in neurocognitive function
October 15, 2018 - Researchers find potential treatment to halt premature labor and birth
October 15, 2018 - As U.S. suicides rates rise, Hispanics show relative immunity
October 15, 2018 - FDA Issues a Complete Response Letter to Acacia Pharma for Barhemsys
October 15, 2018 - Photoactive bacteria bait may help in fight against MRSA infections
October 15, 2018 - Increasing vigorous exercise reduces risk factors of type 2 diabetes, cardiovascular disease in children
October 15, 2018 - First-of-its-kind study to test a personalized vaccine in cancer patient
October 15, 2018 - Extension trial assesses benefit of switching from flash monitoring to RT-CGM for hypoglycemia
October 15, 2018 - Half of parents say young children are afraid of doctor’s visits
October 15, 2018 - Study shows how fingerprint-based drug screening works on the living and deceased
October 15, 2018 - Study reveals potential to monitor progression of Alzheimer’s disease by measuring brain antioxidant levels
October 15, 2018 - FDA Approves Xarelto to Reduce the Risk of Major Cardiovascular Events in Patients with Chronic Coronary Artery Disease (CAD) or Peripheral Artery Disease (PAD)
October 15, 2018 - Promising new therapeutic approach against Ebola virus identified
October 15, 2018 - Study unravels how cancer stem cells use normal genes in abnormal ways
October 15, 2018 - Healthcare systems fail to deliver at affordable prices finds report
October 15, 2018 - Intensive BP Therapy in Diabetes May Lower Risk for CV Events
October 15, 2018 - Muscle relaxants increase risk of respiratory complications
October 15, 2018 - Female birds become more promiscuous after hatchings fail in the first breeding attempt
October 15, 2018 - Humans occupied Madagascar thousands of years later than previously thought
October 15, 2018 - Is Kidney Dialysis Always Needed When Septic Shock Strikes?
October 15, 2018 - Study shows invasive lung cancer surgery can lead to long-term opioid use
October 15, 2018 - Sugar, a “sweet” tool to understand brain injuries
October 14, 2018 - King’s commemorates activities and research on World Arthritis Day
October 14, 2018 - Humana and VFW NY team up on Stop 22 initiative to increase awareness of veterans committing suicide
October 14, 2018 - Water fluoridation contributes to urinary fluoride levels in pregnant women in Canada
October 14, 2018 - Study of children in Romanian orphanages tells cautionary tale about family separation
October 14, 2018 - Previous Endologix AFX Safety Notice classified by FDA as Class I recall
October 14, 2018 - Legal scholars sound alarm on academies’ report about returning research results to participants
October 14, 2018 - UNIST selects six extraordinary scholars to be induced as ‘Rising-star Distinguished Professor’
October 14, 2018 - Scientists find new way to help asthmatics breathe more easily
October 14, 2018 - New ‘gag rule’ may adversely impact health care of pregnant women
October 14, 2018 - Rosacea – Genetics Home Reference
October 14, 2018 - When the fighting crosses the line
October 14, 2018 - New findings could benefit patients with triple-negative breast cancer
October 14, 2018 - UK Biobank provides wealth of information for further genetic studies
October 14, 2018 - KHN’s ‘What the Health?’ Falling premiums and rising political tensions
October 14, 2018 - Duvelisib Promising for Chronic Lymphocytic Leukemia, SLL
October 14, 2018 - Tailored drug cocktails offer hope to kids with aggressive brain tumors
October 14, 2018 - Common gene variants linked to migraine risk in African-American children
October 14, 2018 - Funding requests are being accepted by BlueCross BlueShield of Tennessee Community Trust
October 14, 2018 - Using pulsed electric fields in cancer therapy
October 14, 2018 - Major Childbirth Complications More Likely for Black Women
October 14, 2018 - Young cancer survivors at greater risk of mental health disorders
October 14, 2018 - Common herbicide compound could help fight hospital-acquired fungal infections
October 14, 2018 - Alterations in genes encoding proteins contribute to ADHD development
October 14, 2018 - New patient-centric website launched in Europe to empower people with chronic conditions
October 14, 2018 - Antimicrobial signaling molecule has lower activity against hepatitis C virus in most humans
October 14, 2018 - Genomic dark matter activity connects Parkinson’s and psychiatric diseases
October 14, 2018 - Cornell dots equipped with antibody fragments offer a new cancer weapon
October 14, 2018 - Addressing social and cultural factors is key to reducing burden of type 2 diabetes
October 14, 2018 - Study reveals why females age more slowly than males
October 14, 2018 - DNA vaccine shown to provide long-term protection from Ebola
October 14, 2018 - Gene therapy shown to remove core component of Parkinson’s disease
October 14, 2018 - Obamacare premiums dip for first time. Some call it a correction
October 14, 2018 - Scientists use haploid stem cells to produce mice with same-sex parents
October 14, 2018 - New transgenic mouse model sheds light on biological causes of Parkinson’s disease
Is older blood OK to make use of in a transfusion?

Is older blood OK to make use of in a transfusion?

image_pdfDownload PDFimage_print
blood
Credit score: Wikimedia Commons

(HealthDay)—The use of older pink blood cells to provide transfusions to significantly unwell sufferers does not seem to impact their chance of demise, Australian researchers file.

It was once as soon as believed that contemporary pink blood cells had been perfect suited to transfusions. However this new find out about provides to the proof that older blood is solely as just right, if no longer higher, the find out about authors mentioned.

“Crimson blood cells for transfusion for significantly unwell sufferers are like a just right pink wine—a bit of older, a bit of higher,” mentioned researcher Dr. Jamie Cooper. He’s professor and director of the Australian and New Zealand Extensive Care Analysis Heart at Monash College in Melbourne.

Learn about co-author Alistair Nichol added that a large number of insufficient analysis had steered that more energizing blood can be higher to make use of in significantly unwell sufferers. Nichol is an affiliate professor of epidemiology and preventive medication within the College of Public Well being and Preventive Medication at Monash College.

The present apply is to make use of the oldest to be had blood, Nichol mentioned. Crimson blood cells may also be saved for as much as 42 days, the researchers famous.

“However because of considerations about the usage of older blood, some blood banks have been lowering the age of the blood they transfuse,” Nichol mentioned. Decreasing the age of blood for transfusions, then again, would possibly lead to extra blood shortages, he identified.

“The present apply is secure and docs now not want to check out and get the most up to date to be had blood for his or her sufferers,” Nichol mentioned. He added that the use of more moderen blood to provide transfusions to significantly unwell sufferers could also be damaging.

Cooper mentioned, “We discovered two sudden findings which enhance the usage of older blood.”

Transfusion reactions had been extra commonplace with more energizing blood, and maximum critically unwell sufferers had higher survival after they won older pink blood cells, he defined.

As well as, the use of older blood will make extra blood to be had for transfusions, Cooper mentioned.

“Blood availability for transfusion will build up international, as a result of transfusion services and products will now keep away from offering more energizing blood for decided on affected person teams,” he mentioned.

“Nations who’ve lowered their blood garage time from 42 to 35 days via considerations about blood age will have to imagine transferring again to the usual 42 days,” Cooper steered.

From November 2012 via December 2016, the researchers randomly assigned just about five,000 significantly unwell sufferers to obtain blood transfusions with both more moderen or older blood. The sufferers had been from 59 scientific facilities in 5 international locations—Australia, Finland, Eire, New Zealand and Saudi Arabia.

More moderen blood have been saved for a mean of 11 days, whilst older blood was once about 22 days previous.

90 days after the transfusion, 24.eight p.c of sufferers who won more moderen blood died, whilst 24.1 p.c of those that had won older blood died, the findings confirmed.

After six months, the variation in deaths between those that won more moderen or older blood remained lower than 1 p.c.

In step with Dr. Edward Murphy, a professor of laboratory medication on the College of California, San Francisco, “Those findings are in step with different contemporary research.”

Saved blood deteriorates because it ages, and it was once a priority that those adjustments in blood may hurt sufferers, mentioned Murphy, who was once no longer concerned with the brand new find out about.

As an example, as blood will get older, the pink cells get stiffer and may free up iron as hemoglobin leaks out of the cells. There was once additionally worry that the fluid and the plastic luggage used to retailer the pink blood cells may impact the cells, Murphy mentioned.

“To my thoughts, the problem is settled that there’s no longer a vital distinction in results associated with the way you retailer the blood cells,” Murphy mentioned. “It is reassuring that there is not any distinction.”

The file was once revealed on-line Sept. 27 within the New England Magazine of Medication to coincide with the presentation of the find out about findings on the Eu Society of Extensive Care Medication assembly in Vienna, Austria.


Discover additional:
World find out about proves previous blood is as just right as new

Additional info:
Alistair Nichol, Ph.D., affiliate professor epidemiology and preventive medication, College of Public Well being and Preventive Medication, Monash College,Melbourne, Australia; Jamie Cooper, M.D., professor and director, Australian and New Zealand Extensive Care Analysis Centre, Monash College,Melbourne, Australia; Edward Murphy, M.D., M.P.H., professor, laboratory medication, College of California, San Francisco; Sept. 27, 2017, New England Magazine of Medication, on-line, and presentation, Eu Society of Extensive Care Medication, Vienna, Austria

For extra on blood transfusions, seek advice from the U.S. Nationwide Center, Lung, and Blood Institute.

Magazine reference:
New England Magazine of Medication

Tagged with:

About author

Related Articles