Breaking News
July 19, 2018 - Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice
July 19, 2018 - Study finds major discrepancies in prescription drug labeling pregnancy information across four countries
July 19, 2018 - Cellectar’s CLR 131 Receives FDA Orphan Drug Designation for Treatment of Ewing’s Sarcoma
July 19, 2018 - Watching the immune system in action reveals what happens when things goes wrong
July 19, 2018 - Increasing blood sugar levels improves memory and performance in older adults
July 19, 2018 - Connection between self-regulation and obesity appears to be different for girls and boys
July 19, 2018 - Researchers develop new, less destructive method for whitening teeth
July 19, 2018 - Revving up innate control of viral infection requires a three-cell ignition
July 19, 2018 - Inaccurate direct-to-consumer raw genetic data can harm patients, new research suggests
July 19, 2018 - Weight loss surgery is effective under the right situations
July 19, 2018 - BioTek awarded patent for autofocus feature on microplate reader
July 19, 2018 - Low-carb diets reduce stiffness of arteries in women and promote weight loss in men
July 19, 2018 - New review examines cannabinoids’ potential for direct treatment of cancer
July 19, 2018 - Allergic responses may help protect the skin against cancer, research suggests
July 19, 2018 - Inappropriate Prescribing of Abx High in Urgent Care Centers
July 19, 2018 - Many at risk for HIV despite lifesaving pill
July 19, 2018 - Tips for doctors and parents on the harms of marijuana use for teens
July 18, 2018 - Researchers detect presence of IgE antibodies after kidney transplantation
July 18, 2018 - New technique allows researchers to create large scale, personalized bone grafts
July 18, 2018 - Smoking May Boost Atrial Fibrillation Risk
July 18, 2018 - Genome editing method targets AIDS virus
July 18, 2018 - These things matter: Medical complications are not inevitable, a physician writes
July 18, 2018 - Cognitive functions often wilt as water departs the body, shows study
July 18, 2018 - Origins of bread found 14,400 years ago in Jordan
July 18, 2018 - Low-dose ketamine found to be as effective as opioids for treating acute pain
July 18, 2018 - Novel bioengineering technique could help repair bone defects
July 18, 2018 - Researchers identify new potential target protein for colon cancer
July 18, 2018 - Air pollution contributes significantly to diabetes globally
July 18, 2018 - Cell membrane’s importance offers new strategy to fight infections
July 18, 2018 - Researchers identify key protein involved in irregular brain cell activity
July 18, 2018 - 3D modeling of drug resistance could lead to more effective cancer treatment
July 18, 2018 - Hunger hormones could be key to new treatments for drug, alcohol addiction
July 18, 2018 - Nitrate-cured meats may contribute to mania, study finds
July 18, 2018 - Why men may recover more quickly from influenza infections than women
July 18, 2018 - Study finds discharge against medical advice as predictor of readmissions in heart attack patients
July 18, 2018 - KemPharm Announces Top Line Results from KP415.E01 Efficacy and Safety Trial in Children With ADHD
July 18, 2018 - Self-control and obesity: Gender matters in children
July 18, 2018 - Bioengineers, diabetes researchers convene to discuss future concepts for precision medicine
July 18, 2018 - New findings support more conservative use of ED neuroimaging for non-index seizures
July 18, 2018 - Practicing yoga benefits pregnant women, study suggests
July 18, 2018 - New strategy may lead to more accurate breast cancer diagnoses
July 18, 2018 - FDA Approves Symtuza (D/C/F/TAF), the First and Only Complete Darunavir-Based Single-Tablet Regimen for the Treatment of HIV-1 Infection
July 18, 2018 - New guide helps hospitals pick right partner to handle hospitalist services
July 18, 2018 - Deep data dive helps predict cerebral palsy
July 18, 2018 - Stricter firearm legislation associated with reduced murder and suicide rates
July 18, 2018 - Physical and sexual abuse in childhood associated with endometriosis risk
July 18, 2018 - Omega 3 supplements do not reduce risk of heart disease, stroke or death
July 18, 2018 - GSA’s new publication provides support for safe use of OTC analgesics by older adults
July 18, 2018 - Researchers receive grant from U.S. Department of Education to study children with HFASD
July 18, 2018 - Early childhood adversity increases sensitivity of the body’s immune response to cocaine
July 18, 2018 - Parental incarceration affects health behaviors of children in adulthood
July 18, 2018 - Researchers find that yellow fever and Asian tiger mosquitoes can carry new virus
July 18, 2018 - Two Regimens Fail to Stop Declines in β-Cell Function
July 18, 2018 - Researchers apply computing power to track the spread of cancer
July 18, 2018 - Olfactory receptors play pathophysiological role in all organs than merely smell perception
July 18, 2018 - Fish consumption associated with lower risk of early death
July 18, 2018 - MR Solutions’ 7T MRI imaging system installed at University of Hawaii
July 18, 2018 - Humorous ads screened around World Cup game achieve higher biometric response than sporty ads
July 18, 2018 - New study demonstrates little effect of hormone therapy on artery thickness
July 18, 2018 - A 3-Pronged Plan to Cut Type 2 Diabetes Risk
July 18, 2018 - New clues to sepsis may speed diagnosis
July 18, 2018 - Stars of Stanford Medicine: Improving cardiovascular health in Africa and beyond
July 18, 2018 - Heart attack risk continues to increase among pregnant women, study finds
July 18, 2018 - Few tips to help avoid sunburns in summer
July 18, 2018 - High-fat diet and systemic inflammation contribute to progression of prostate cancer
July 18, 2018 - Researchers develop 3D map of gene interactions that play key role in heart disease
July 18, 2018 - Conservative management of lung subsolid nodules reduces overtreatment and unnecessary surgery
July 18, 2018 - Report warns of dog illness that can spread to owners
July 18, 2018 - A winning essayist’s tips for keeping track of scientific facts
July 18, 2018 - Researchers seek to understand role of APOE mutation in Alzheimer’s disease
July 18, 2018 - Animal studies reveal brain changes responsible for appetite effects of cannabis
July 18, 2018 - New ZEISS ZEN Intellesis machine allows segmentation of correlative microscopy
July 18, 2018 - Study findings highlight importance of early detection of SMA through newborn screening
July 18, 2018 - Results of Phase III (PIX306) Trial Evaluating Progression-Free Survival of Pixuvri (pixantrone) Combined with Rituximab in Patients with Aggressive B-cell Non-Hodgkin Lymphoma
July 18, 2018 - Diabetes researchers find switch for fatty liver disease
July 18, 2018 - The future of the microbiome: A conversation
July 18, 2018 - States attacking ACA would hurt most if shield on preexisting conditions were axed
July 18, 2018 - Novel delivery system for bacteriophages could offer new way to battle lung infections
July 18, 2018 - PTSD may increase risk of stroke, heart attack in World Trade Center response crews
July 18, 2018 - Finding the right protective eyewear for young athletes
Is older blood OK to make use of in a transfusion?

Is older blood OK to make use of in a transfusion?

image_pdfDownload PDFimage_print
Credit score: Wikimedia Commons

(HealthDay)—The use of older pink blood cells to provide transfusions to significantly unwell sufferers does not seem to impact their chance of demise, Australian researchers file.

It was once as soon as believed that contemporary pink blood cells had been perfect suited to transfusions. However this new find out about provides to the proof that older blood is solely as just right, if no longer higher, the find out about authors mentioned.

“Crimson blood cells for transfusion for significantly unwell sufferers are like a just right pink wine—a bit of older, a bit of higher,” mentioned researcher Dr. Jamie Cooper. He’s professor and director of the Australian and New Zealand Extensive Care Analysis Heart at Monash College in Melbourne.

Learn about co-author Alistair Nichol added that a large number of insufficient analysis had steered that more energizing blood can be higher to make use of in significantly unwell sufferers. Nichol is an affiliate professor of epidemiology and preventive medication within the College of Public Well being and Preventive Medication at Monash College.

The present apply is to make use of the oldest to be had blood, Nichol mentioned. Crimson blood cells may also be saved for as much as 42 days, the researchers famous.

“However because of considerations about the usage of older blood, some blood banks have been lowering the age of the blood they transfuse,” Nichol mentioned. Decreasing the age of blood for transfusions, then again, would possibly lead to extra blood shortages, he identified.

“The present apply is secure and docs now not want to check out and get the most up to date to be had blood for his or her sufferers,” Nichol mentioned. He added that the use of more moderen blood to provide transfusions to significantly unwell sufferers could also be damaging.

Cooper mentioned, “We discovered two sudden findings which enhance the usage of older blood.”

Transfusion reactions had been extra commonplace with more energizing blood, and maximum critically unwell sufferers had higher survival after they won older pink blood cells, he defined.

As well as, the use of older blood will make extra blood to be had for transfusions, Cooper mentioned.

“Blood availability for transfusion will build up international, as a result of transfusion services and products will now keep away from offering more energizing blood for decided on affected person teams,” he mentioned.

“Nations who’ve lowered their blood garage time from 42 to 35 days via considerations about blood age will have to imagine transferring again to the usual 42 days,” Cooper steered.

From November 2012 via December 2016, the researchers randomly assigned just about five,000 significantly unwell sufferers to obtain blood transfusions with both more moderen or older blood. The sufferers had been from 59 scientific facilities in 5 international locations—Australia, Finland, Eire, New Zealand and Saudi Arabia.

More moderen blood have been saved for a mean of 11 days, whilst older blood was once about 22 days previous.

90 days after the transfusion, 24.eight p.c of sufferers who won more moderen blood died, whilst 24.1 p.c of those that had won older blood died, the findings confirmed.

After six months, the variation in deaths between those that won more moderen or older blood remained lower than 1 p.c.

In step with Dr. Edward Murphy, a professor of laboratory medication on the College of California, San Francisco, “Those findings are in step with different contemporary research.”

Saved blood deteriorates because it ages, and it was once a priority that those adjustments in blood may hurt sufferers, mentioned Murphy, who was once no longer concerned with the brand new find out about.

As an example, as blood will get older, the pink cells get stiffer and may free up iron as hemoglobin leaks out of the cells. There was once additionally worry that the fluid and the plastic luggage used to retailer the pink blood cells may impact the cells, Murphy mentioned.

“To my thoughts, the problem is settled that there’s no longer a vital distinction in results associated with the way you retailer the blood cells,” Murphy mentioned. “It is reassuring that there is not any distinction.”

The file was once revealed on-line Sept. 27 within the New England Magazine of Medication to coincide with the presentation of the find out about findings on the Eu Society of Extensive Care Medication assembly in Vienna, Austria.

Discover additional:
World find out about proves previous blood is as just right as new

Additional info:
Alistair Nichol, Ph.D., affiliate professor epidemiology and preventive medication, College of Public Well being and Preventive Medication, Monash College,Melbourne, Australia; Jamie Cooper, M.D., professor and director, Australian and New Zealand Extensive Care Analysis Centre, Monash College,Melbourne, Australia; Edward Murphy, M.D., M.P.H., professor, laboratory medication, College of California, San Francisco; Sept. 27, 2017, New England Magazine of Medication, on-line, and presentation, Eu Society of Extensive Care Medication, Vienna, Austria

For extra on blood transfusions, seek advice from the U.S. Nationwide Center, Lung, and Blood Institute.

Magazine reference:
New England Magazine of Medication

Tagged with:

About author

Related Articles