Breaking News
January 24, 2018 - Study illustrates role of specific antibodies in protection against influenza
January 24, 2018 - Curcumin could provide meaningful cognitive benefits, study suggests
January 24, 2018 - Tenax Therapeutics Announces Plan to Develop Levosimendan for a Pulmonary Hypertension Indication with No FDA Approved Therapies
January 24, 2018 - EndoBreak: Obesity in 2018; Diabetes Risks in Pregnancy
January 24, 2018 - Recommendations to improve the quality of ultrasound imaging in obstetrics and gynecology
January 24, 2018 - Sensory feedback facilitates enhanced brainwave control of portable hand-exoskeleton
January 24, 2018 - Innovative system helps medical staff to accurately evaluate patients’ risk of falling
January 24, 2018 - Porvair Sciences to showcase microplate and chromatography products at Analytica 2018
January 24, 2018 - Children with cochlear implant learn words faster than kids with normal hearing
January 24, 2018 - Ionis’ Inotersen NDA Accepted for Priority Review by the FDA
January 24, 2018 - Abuse-Deterrent Opioid No Help in Australia
January 24, 2018 - Maternal mortality rates are on the rise, but more accurate estimates are needed
January 24, 2018 - New essential oil inhaler facilitates pain management
January 24, 2018 - USPSTF: Insufficient Evidence to Screen Kids for Scoliosis
January 24, 2018 - Team develops method to identify seizure-causing regions in the brain
January 24, 2018 - New report takes comprehensive look at health effects of e-cigarettes
January 24, 2018 - Researchers develop new indicator for assessing active aging
January 24, 2018 - Research highlights decreasing trend in traditional hysterectomy
January 24, 2018 - Computer-based speech analysis has potential to improve prediction of psychosis
January 24, 2018 - New family of FFPE reagent kits launched by Beckman Coulter Life Sciences
January 24, 2018 - Researchers use epigenetic signatures to advance diagnosis for neurodevelopmental disorders
January 24, 2018 - EPI report reveals air quality as major environmental threat to public health
January 23, 2018 - How to Fight the Flu This Season
January 23, 2018 - Mixed Data for Fatty Acid Intake and Glaucoma
January 23, 2018 - The brains of jazz and classical pianists work differently
January 23, 2018 - Scientists identify protein biomarkers to track patients with Hutchinson-Gilford progeria syndrome
January 23, 2018 - Exercise could extend the life expectancy of breast cancer survivors, study states
January 23, 2018 - Researchers show association between microbiome and cancer-related blood infections
January 23, 2018 - Cancer.com Site Sat Dormant for 10 Years. Now It’s Live Again.
January 23, 2018 - FDA’s program to speed up drug approval shaved nearly a year off the process
January 23, 2018 - Study reveals key challenges and frustrations associated with current RTSM/IRT solutions
January 23, 2018 - Researchers unravel function of protein ‘smallish’
January 23, 2018 - Infants born in withdrawal due to opioid exposure in utero show abnormalities
January 23, 2018 - Researchers block common siren call of glioblastoma and metastatic breast cancer
January 23, 2018 - FDA Accepts New Drug Applications for Merck’s Doravirine, the Company’s Investigational Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), for Treatment of HIV-1 Infection
January 23, 2018 - Six Concerns About Practice Consolidation
January 23, 2018 - How Alzheimer’s Changes the Brain
January 23, 2018 - Pharmaceutical stirs outrage over price hike for brain tumor drug
January 23, 2018 - University under fire for off-the-grid herpes vaccine experiments
January 23, 2018 - Gastric environment permanently changes in the presence of Helicobacter pylori infection
January 23, 2018 - Scientists take tissue-engineering approach to improve healing related to skeletal system
January 23, 2018 - Consumption of dietary fiber can prevent obesity and metabolic syndrome, study shows
January 23, 2018 - FDA Alert: Multiple Drug Products by Flawless Beauty: Recall
January 23, 2018 - Rhymes with Amyloid: That’s Improbable!
January 23, 2018 - CLCN2-related leukoencephalopathy – Genetics Home Reference
January 23, 2018 - Can road salt and other pollutants disrupt our circadian rhythms?
January 23, 2018 - ‘Depression literacy’ program encourages many teens to seek adult help
January 23, 2018 - New initiative seeks to transform the way people live with dementia
January 23, 2018 - Isosec introduces first Virtual Smartcard for NHS Trusts and clinicians
January 23, 2018 - New report reveals rapid growth in Vietnam pharmaceutical market
January 23, 2018 - Obamacare Led to Rise in Breast Cancer Screening
January 23, 2018 - Bariatric Tx Bests Usual Care for Long-Term Health
January 23, 2018 - Keep Your Dogs and Cats Safe From Holiday Hazards
January 23, 2018 - New AI technology significantly improves human kidney analysis
January 23, 2018 - In Trump’s first year, anti-abortion forces make strides despite setbacks
January 23, 2018 - Small PFS Bump in Gastric/GEJ Cancer
January 23, 2018 - Defending against environmental stressors may shorten lifespan
January 23, 2018 - Researchers create cavitation bubbles to remove dental plaque
January 23, 2018 - Discovery offers fresh perspective on how the brain keeps its balance
January 23, 2018 - Opioid exposure linked to physical abnormalities in newborns
January 23, 2018 - Study identifies genes involved in latent asymptomatic state of breast cancer metastases
January 23, 2018 - Kala Pharmaceuticals Announces New Drug Application for Inveltys (KPI-121 1%) Has Been Accepted for Review by the U.S. Food and Drug Administration
January 23, 2018 - Closer Look at Household Contacts Finds More TB Cases
January 23, 2018 - Type 1 IFNs may mediate Zika pregnancy complications
January 23, 2018 - Anti-inflammatory pill could help make vaccines more effective for the elderly
January 23, 2018 - New discovery sheds light on iron-restricted anemia that causes fatigue in millions
January 23, 2018 - BMG LABTECH’s Australian office celebrates 20 years of innovation and growth in APAC region
January 23, 2018 - FDA Alert: Basic Drugs Brand of Senna Laxative by Magno-Humphries Laboratories: Recall
January 23, 2018 - Chronic Opioid Use High Among IBD Patients
January 23, 2018 - New long-acting, less-toxic HIV drug suppresses virus in humanized mice
January 23, 2018 - Findings provide better understanding of cognitive inflexibility in Fragile X Syndrome
January 23, 2018 - Powerful anti-oxidant can stop progression of fatty liver disease in young mice
January 23, 2018 - Marijuana use does not lower probability of conception, study shows
January 23, 2018 - Study shows value of occupational therapy in the lives of young adults with diabetes
January 23, 2018 - Chinese researchers develop multifunctional vehicle to transport gene therapeutics
January 23, 2018 - Researchers seek to understand effect of very low birth weight on the brain
January 23, 2018 - Be a Savvy Supermarket Shopper
January 23, 2018 - NIH Striving to Avoid False Hope in Chronic Fatigue
January 23, 2018 - ClinicalTrials.gov: Occupational Stress
January 23, 2018 - PrEP could make US easily hit its 2020 HIV prevention goal, study finds
Fast, Simple Zika Take a look at Evolved

Fast, Simple Zika Take a look at Evolved

image_pdfDownload PDFimage_print

HealthDay news image

WEDNESDAY, Sept. 27, 2017 (HealthDay Information) — A brand new speedy, simple and inexpensive “dipstick” check for the Zika and dengue viruses may just revolutionize public well being reaction to bad tropical germs, a brand new learn about studies.

The check correctly diagnoses Zika and dengue and will inform the 2 mosquito-borne viruses aside, a space through which commercially to be had checks now stumble, stated senior researcher Lee Gehrke, a professor with the MIT Institute for Scientific Engineering and Science.

“In gentle of the issues with Zika virus inflicting microcephaly [a genetic abnormality resulting in a smaller-than-normal head] and different defects in small children born to inflamed moms, it is crucial a pregnant girl would know if her fever is led to by way of Zika virus or dengue virus,” stated Gehrke, who is additionally a professor at Harvard Scientific College.

The brand new check resembles a being pregnant check strip, Gehrke famous. The strip comprises antibodies that react to the presence of Zika or dengue virus, and gold nanoparticles that reply to the antibody response.

To make use of the check, a scientific skilled would dip the strip right into a tube of both blood serum or complete blood.

“If this is a certain check, then we see a dot or a line at the check that effects from seeing the gold nanoparticles that sign the antibodies spotting the viral protein,” Gehrke stated.

The check can inform Zika from dengue, and likewise can distinguish amongst 4 other lines of dengue, Gehrke added.

Zika and dengue each belong to the similar viral circle of relatives, which might be referred to as flaviviruses.

“They’re two intently similar viruses unfold by way of the similar mosquito,” stated co-researcher Kimberly Hamad-Schifferli, an affiliate professor of engineering with the College of Massachusetts in Boston.

The analysis crew, which additionally integrated individuals from Mount Sinai College of Medication in New York Town, evolved the brand new check as a result of present checking out merchandise now and again cross-react between Zika and dengue, offering a false certain for Zika when the affected person in fact has the opposite virus, Gehrke stated.

Researchers checked the accuracy of the check by way of checking out blood serum samples taken from other people in areas the place Zika has hit toughest, together with Brazil, Colombia, Guatemala, India, Mexico and Panama. Critical start defects led to by way of Zika seemed for the primary time within the western hemisphere in 2015 in northern Brazil; then the epidemic swept outward.

“We validated the check within the spaces the place the virus is located, the usage of human serum from inflamed sufferers,” Gehrke stated. “This isn’t only a check we carried out the usage of fabrics in a laboratory. We in fact traveled to the endemic spaces.”

The check proved 80 % to 90 % correct in detecting Zika and fending off false positives, Hamad-Schifferli stated.

It’s going to take a couple of 12 months to get the check out in the marketplace in Zika-impacted spaces, for the reason that generation is according to present merchandise like being pregnant checks, Hamad-Schifferli stated.

The check additionally is anticipated to be very inexpensive. Lately, subject matter prices are about $five according to strip, however Gehrke stated prices will have to decline as manufacturing will get rolling.

“Our goal is below $1 according to strip, which we predict is affordable as soon as the antibody manufacturing is scaled up,” Gehrke stated. “The gold nanoparticles are already moderately affordable.”

Infectious illness professional Dr. Amesh Adalja stated the brand new check “will satisfy an excellent want and be of top price.

“The provision of speedy, delicate and particular diagnostic checks is the most important for the id, remedy, and keep an eye on of infectious illness,” stated Adalja, a senior go together with the Johns Hopkins Middle for Well being Safety in Baltimore.

He added, ” speedy antigen check that meets this standards is possible for dengue and Zika — two clinically indistinguishable sicknesses with other prognoses — is a big step ahead.”

The brand new record seems Sept. 27 within the magazine Science Translational Medication.

SOURCES: Lee Gehrke, Ph.D., professor, Massachusetts Institute of Generation, Institute for Scientific Engineering and Science, and professor, Harvard Scientific College, Cambridge, Mass.; Kimberly Hamad-Schifferli, Ph.D., affiliate professor, engineering, College of Massachusetts, Boston; Amesh Adalja, M.D., senior affiliate, Johns Hopkins Middle for Well being Safety, Baltimore; Sept. 27, 2017, Science Translational Medication

Information tales are written and equipped by way of HealthDay and don’t mirror federal coverage, the perspectives of MedlinePlus, the Nationwide Library of Medication, the Nationwide Institutes of Well being, or the U.S. Division of Well being and Human Services and products.

Tagged with:

About author

Related Articles