Breaking News
November 24, 2017 - Video game improves balance in youth with autism
November 24, 2017 - Chromatrap introduces easy-to-use range of DNA kits for molecular biology applications
November 24, 2017 - Bacteria in the intestine can play important pacemaker role in peristalsis
November 24, 2017 - Resistance training promotes environmental quality of life and sense of coherence in older people
November 24, 2017 - Research suggests genome’s spatial organization as important switch for defining cell types
November 24, 2017 - Study highlights need for more clinical trials to improve treatment of children with heart disease
November 24, 2017 - Quickly Treating Mini-Stroke Can Cut Risk for Future Stroke
November 24, 2017 - Inclusion in mainstream school can exacerbate feelings of being ‘different’ in pupils with autism spectrum conditions
November 24, 2017 - Fat-busting ingredients in cinnamon
November 24, 2017 - IMeasureU introduces IMU Step for tracking movements of professional, amateur athletes
November 24, 2017 - Study uncovers key mechanism by which tumors develop resistance to radiation therapy
November 24, 2017 - This Thanksgiving, carve out time for lively discourse on end-of-life wishes
November 24, 2017 - Creutzfeldt-Jakob disease patients harbor infectious prions in their skin
November 24, 2017 - Call for ‘renewed focus’ on deadly threat from antibiotic resistance
November 24, 2017 - 14 signs your daughter may have ADHD
November 24, 2017 - ACA appears to have encouraged more people to use preventive care for heart health
November 23, 2017 - UVA researchers developing new tool to help cancer patients make complex care decisions
November 23, 2017 - SITC releases first consensus recommendations on managing immunotherapy side effects
November 23, 2017 - Research shows major shift in eye surgeries from hospitals to ambulatory surgery centers
November 23, 2017 - Multiple sclerosis drug can beat obstinate bacteria
November 23, 2017 - Maintaining sufficient vitamin D levels may help to prevent rheumatoid arthritis
November 23, 2017 - Heart disease risk factors linked to walking difficulties in people under age of 78
November 23, 2017 - UVA scientists working to find end-around method to stop triple-negative breast cancer
November 23, 2017 - Researchers develop new tool to share clinico-genomic data
November 23, 2017 - New analysis identifies five distinct patient clusters that may need different approaches to manage asthma
November 23, 2017 - Study shows education and poverty affect outcomes of total knee replacement
November 23, 2017 - Research paves way for development of vaccines against mycoplasma bacteria
November 23, 2017 - Season of festivities can increase opportunities to overindulge in alcohol
November 23, 2017 - Methotrexate drug holiday improves flu vaccine efficacy in rheumatoid arthritis patients
November 23, 2017 - Study identifies signaling pathway essential for growth of new blood vessels
November 23, 2017 - OBD presents results of immunotherapy studies at FNIH Biomarker Consortium Cancer Steering Committee’s annual meeting
November 23, 2017 - New study shows how SNO reaction may contribute to Parkinson’s disease
November 23, 2017 - Study highlights need to improve quality of cardiovascular care for HIV-positive adults
November 23, 2017 - New intelligence tool provides clarity to scientists in booming immuno-oncology field
November 23, 2017 - Cancer Survivors Can Develop PTSD, Too
November 23, 2017 - One step closer toward a treatment for Alzheimer’s disease?
November 23, 2017 - Scientists detect pathological prion protein in skin of CJD patients
November 23, 2017 - Bacterial colonization can function as a pacemaker for the intestine, study reveals
November 23, 2017 - Preclinical study shows clear path toward effective treatment for rare bone disease
November 23, 2017 - Displaced Puerto Ricans face obstacles getting health care
November 23, 2017 - High-intensity exercise improves memory, study finds
November 23, 2017 - Researchers compare shunts and stents to maintain blood flow in infants with heart disease
November 23, 2017 - Gold nanoparticles could potentially help in more effective drug delivery
November 23, 2017 - Moderate coffee consumption more likely to provide beneficial health outcomes
November 23, 2017 - ESMO Consortium Study advocates for equal access to quality cancer treatment across Asia
November 23, 2017 - Gut bacteria at young age can contribute to MS onset and progression, study suggests
November 23, 2017 - Australian government urged to sue tobacco companies
November 23, 2017 - OB/GYN vs PCP: Who Should Handle Sexual Health?
November 23, 2017 - A Teen Mom’s Stress May Harm Her Heart: MedlinePlus Health News
November 23, 2017 - How SORLA protects against Alzheimer’s disease
November 23, 2017 - Newly discovered drug-like compound may revolutionize treatment of autoimmune diseases
November 23, 2017 - Comprehensive review finds increasing number of new heart failure cases in the UK
November 23, 2017 - Leishmania adaptation to environmental changes results from frequent chromosomal amplifications
November 23, 2017 - People who use indoor firing ranges at risk of lead poisoning
November 23, 2017 - Tiny robots could pave way for treating illness in hard-to-reach areas of the body
November 23, 2017 - Study finds smokers wrongly believe Natural American Spirit cigarettes are healthier
November 23, 2017 - Cancer patients willing to swap drug efficacy for reduced risk of adverse events
November 23, 2017 - Oncologists find new biomarker for breast cancer having poor prognosis
November 23, 2017 - Scientists show how diaper phantoms can improve tumor measurements
November 23, 2017 - Metabolites significantly affected in chronic kidney disease, study finds
November 23, 2017 - AR and VR technologies hold potential to increase attractiveness of healthy foods
November 23, 2017 - Amazon Filters offers SupaPore H0P filters for fermentation applications
November 23, 2017 - FDA Approves Genentech’s Gazyva for Previously Untreated Advanced Follicular Lymphoma
November 23, 2017 - Does Sex Really Trigger Cardiac Arrest?: MedlinePlus Health News
November 23, 2017 - Baby-boomers and millennials more afflicted by the opioid epidemic
November 23, 2017 - UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research
November 23, 2017 - Researchers question exclusion of people with prior cancer history from clinical trials
November 23, 2017 - New mechanism in cancer cells to disarm attacking immune cells, study reveals
November 23, 2017 - Most U.S. Parents Can’t Find Good Childcare: Survey
November 23, 2017 - Alpha-fetoprotein (AFP) Test: MedlinePlus Lab Test Information
November 23, 2017 - Opening windows and doors may improve sleep
November 23, 2017 - Research shows how HLF gene affects blood cell development
November 23, 2017 - Deaths due to diabetes higher than expected in Germany
November 23, 2017 - Study finds improvement in men’s health and negative health trend among women
November 23, 2017 - Study finds specific tumor environment that stimulates cancer cells to metastasize
November 23, 2017 - Problems with your hospital care? Speak up!
November 23, 2017 - Thyroid cancer survivors have higher risk for aging-related diseases
November 23, 2017 - Is a common shoulder surgery useless?
November 23, 2017 - Palliative care services help cancer patients
November 23, 2017 - Anti-diabetic drug can enhance repair of UV-induced DNA damage in cells of ‘Moon children’
Fast, Simple Zika Take a look at Evolved

Fast, Simple Zika Take a look at Evolved

image_pdfDownload PDFimage_print

HealthDay news image

WEDNESDAY, Sept. 27, 2017 (HealthDay Information) — A brand new speedy, simple and inexpensive “dipstick” check for the Zika and dengue viruses may just revolutionize public well being reaction to bad tropical germs, a brand new learn about studies.

The check correctly diagnoses Zika and dengue and will inform the 2 mosquito-borne viruses aside, a space through which commercially to be had checks now stumble, stated senior researcher Lee Gehrke, a professor with the MIT Institute for Scientific Engineering and Science.

“In gentle of the issues with Zika virus inflicting microcephaly [a genetic abnormality resulting in a smaller-than-normal head] and different defects in small children born to inflamed moms, it is crucial a pregnant girl would know if her fever is led to by way of Zika virus or dengue virus,” stated Gehrke, who is additionally a professor at Harvard Scientific College.

The brand new check resembles a being pregnant check strip, Gehrke famous. The strip comprises antibodies that react to the presence of Zika or dengue virus, and gold nanoparticles that reply to the antibody response.

To make use of the check, a scientific skilled would dip the strip right into a tube of both blood serum or complete blood.

“If this is a certain check, then we see a dot or a line at the check that effects from seeing the gold nanoparticles that sign the antibodies spotting the viral protein,” Gehrke stated.

The check can inform Zika from dengue, and likewise can distinguish amongst 4 other lines of dengue, Gehrke added.

Zika and dengue each belong to the similar viral circle of relatives, which might be referred to as flaviviruses.

“They’re two intently similar viruses unfold by way of the similar mosquito,” stated co-researcher Kimberly Hamad-Schifferli, an affiliate professor of engineering with the College of Massachusetts in Boston.

The analysis crew, which additionally integrated individuals from Mount Sinai College of Medication in New York Town, evolved the brand new check as a result of present checking out merchandise now and again cross-react between Zika and dengue, offering a false certain for Zika when the affected person in fact has the opposite virus, Gehrke stated.

Researchers checked the accuracy of the check by way of checking out blood serum samples taken from other people in areas the place Zika has hit toughest, together with Brazil, Colombia, Guatemala, India, Mexico and Panama. Critical start defects led to by way of Zika seemed for the primary time within the western hemisphere in 2015 in northern Brazil; then the epidemic swept outward.

“We validated the check within the spaces the place the virus is located, the usage of human serum from inflamed sufferers,” Gehrke stated. “This isn’t only a check we carried out the usage of fabrics in a laboratory. We in fact traveled to the endemic spaces.”

The check proved 80 % to 90 % correct in detecting Zika and fending off false positives, Hamad-Schifferli stated.

It’s going to take a couple of 12 months to get the check out in the marketplace in Zika-impacted spaces, for the reason that generation is according to present merchandise like being pregnant checks, Hamad-Schifferli stated.

The check additionally is anticipated to be very inexpensive. Lately, subject matter prices are about $five according to strip, however Gehrke stated prices will have to decline as manufacturing will get rolling.

“Our goal is below $1 according to strip, which we predict is affordable as soon as the antibody manufacturing is scaled up,” Gehrke stated. “The gold nanoparticles are already moderately affordable.”

Infectious illness professional Dr. Amesh Adalja stated the brand new check “will satisfy an excellent want and be of top price.

“The provision of speedy, delicate and particular diagnostic checks is the most important for the id, remedy, and keep an eye on of infectious illness,” stated Adalja, a senior go together with the Johns Hopkins Middle for Well being Safety in Baltimore.

He added, ” speedy antigen check that meets this standards is possible for dengue and Zika — two clinically indistinguishable sicknesses with other prognoses — is a big step ahead.”

The brand new record seems Sept. 27 within the magazine Science Translational Medication.

SOURCES: Lee Gehrke, Ph.D., professor, Massachusetts Institute of Generation, Institute for Scientific Engineering and Science, and professor, Harvard Scientific College, Cambridge, Mass.; Kimberly Hamad-Schifferli, Ph.D., affiliate professor, engineering, College of Massachusetts, Boston; Amesh Adalja, M.D., senior affiliate, Johns Hopkins Middle for Well being Safety, Baltimore; Sept. 27, 2017, Science Translational Medication

Information tales are written and equipped by way of HealthDay and don’t mirror federal coverage, the perspectives of MedlinePlus, the Nationwide Library of Medication, the Nationwide Institutes of Well being, or the U.S. Division of Well being and Human Services and products.

Tagged with:

About author

Related Articles