Breaking News
November 18, 2017 - Old World monkeys could be key to a new, powerful rheumatoid arthritis therapy
November 18, 2017 - Mount Sinai researchers identify new therapeutic target for ER+ breast cancer
November 18, 2017 - Age, CRP levels predict success in tapering of biologics in rheumatoid arthritis patients
November 18, 2017 - New dye could be used to observe electrical activity of neurons in the brain
November 18, 2017 - New study further validates use of vaginal progesterone to decrease risk of preterm birth
November 18, 2017 - Russian researcher determined range of reference values for boron in the human body
November 18, 2017 - ‘What the Health?’ Tax bill or health bill?
November 18, 2017 - Could Your Cat Give You ‘Bird Flu?’
November 18, 2017 - Vitamin D Linked to Fertility Outcomes in ART
November 18, 2017 - Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer’s disease
November 18, 2017 - Tax reform proposal could impact care for older Americans
November 18, 2017 - PCSK9 inhibitor offers clinical benefit to patients with peripheral artery disease
November 18, 2017 - Researchers receive £1.3 million to develop sight-saving imaging technology
November 18, 2017 - Novel buckypaper sensor could pave way for high-performance, affordable wearable technology
November 18, 2017 - Despite ACA cost protections, most adolescents skip regular checkups
November 18, 2017 - Stem cell treatment allows paraplegic rats to walk and regain sensory perception
November 18, 2017 - HTC analytical conference comes to the UK
November 18, 2017 - Face It: Drinking, Smoking Takes Toll on Looks: MedlinePlus Health News
November 18, 2017 - New research shows where in the brain the earliest signs of Alzheimer’s occur
November 18, 2017 - Philips announces launch of global movement to raise awareness for COPD
November 18, 2017 - University of Bristol awarded grant to reduce antibacterial drug resistance in Thailand
November 18, 2017 - New oxytocin chemical sensor could be first step towards early diagnosis of autism
November 18, 2017 - Study finds medical cannabis is effective at reducing opioid addiction
November 18, 2017 - Specially tailored, ultrafast light pulses can trigger neurons to fire in different patterns
November 18, 2017 - Decrease in sunshine linked to rising incidence of Rickets
November 18, 2017 - Harnessing social media big data to fight against prescription drug crisis
November 18, 2017 - Researchers find way to switch tumor cells between 2D and 3D morphology
November 18, 2017 - FDA Approves Hemlibra (emicizumab-kxwh) for Hemophilia A with Inhibitors
November 18, 2017 - Adolescents underreport amphetamine use, likely unaware that adderall is amphetamine
November 18, 2017 - Study reveals a reduced risk of teenage eczema in breastfed babies
November 18, 2017 - Separating side effects could pave way for safe, effective pain medications
November 18, 2017 - Gut bacteria at young age can contribute to MS disease onset and progression, study suggests
November 18, 2017 - Environmental triggers may play role in development of Lupus
November 18, 2017 - Review looks into conventional versus new treatment modalities in orthodontic pain management
November 17, 2017 - FDA Alert: Diphenoxylate Hydrochloride and Atropine Sulfate Tablets by Greenstone: Recall
November 17, 2017 - For older women, every movement matters
November 17, 2017 - Talking-based therapy could transform aftercare for cancer survivors
November 17, 2017 - Olympus IXplore SpinSR10 imaging system enables researchers to observe fine details in live cells
November 17, 2017 - Study explores reasons for underrepresentation of minorities in genetic cancer research
November 17, 2017 - California firm running physician practices is closing down as scrutiny ramps up
November 17, 2017 - BMI not valid measure of obesity in postmenopausal women, study shows
November 17, 2017 - Vaginal progesterone decreases the risk of premature birth in women with short cervix
November 17, 2017 - Pricey ER Tests for Chest Pain Often Unnecessary
November 17, 2017 - ‘Old’ Lungs May Be Good Transplant Options: MedlinePlus Health News
November 17, 2017 - How not to gain weight over the holidays
November 17, 2017 - Researchers map first-ever proteome of healthy human heart
November 17, 2017 - Drug used to prevent and treat malaria may also be effective for Zika virus
November 17, 2017 - One in 20 children still receiving codeine to treat pain despite warning from federal regulators
November 17, 2017 - Improving clinical trials with machine learning
November 17, 2017 - Experts identify mental exercise program that can reduce risk of dementia
November 17, 2017 - Just-in-time 3-D implants set to transform tumor surgery
November 17, 2017 - Skin patch offers hope for people with peanut allergy
November 17, 2017 - Scientists identify biomarkers that predict risk of death in Ebola patients
November 17, 2017 - Heart attack, stroke patients have improved outcomes when statins are prescribed after discharge
November 17, 2017 - Majority of people do not understand link between obesity and cancer, study shows
November 17, 2017 - Deep vein thrombosis accurately diagnosed by GPs trained in compression ultrasonography
November 17, 2017 - New Kevlar-based hydrogel recreates the magic of natural cartilage
November 17, 2017 - FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence
November 17, 2017 - Foods made with biofortified corn flour and eggs retain vitamin A after cooking
November 17, 2017 - Integrated Care Winning the Day for Healthcare Companies
November 17, 2017 - CPAP may be superior to gastric banding for severe sleep apnea
November 17, 2017 - New pain relievers reduce opiate overdose risk
November 17, 2017 - Brain astrocytes could play key role in pathogenesis of Alzheimer’s disease
November 17, 2017 - Researchers test whether LVAD surgery could reverse frailty in older adults with heart failure
November 17, 2017 - ATS debuts new video to highlight dangers of flavored tobacco
November 17, 2017 - Medicaid expansion under ACA more likely to increase smoking cessation rates among low-income adults
November 17, 2017 - FDA Approves Mepsevii (vestronidase alfa) for Mucopolysaccharidosis Type VII
November 17, 2017 - 1 in 5 Americans Still Uses Tobacco, Gov’t. Reports: MedlinePlus Health News
November 17, 2017 - People with psychotic-like experiences spend less time in healthy brain states
November 17, 2017 - Hospital Readmission Reduction Program linked to increase in death rates, study finds
November 17, 2017 - Study finds rising rates of marijuana use in states where it is legal
November 17, 2017 - Scientists unveil pathology underlying optic nerve hypoplasia in children
November 17, 2017 - Novel device designed to treat diastolic heart failure found safe and effective
November 17, 2017 - Smoking parents may underestimate kid’s exposure to secondhand smoke
November 17, 2017 - FAIMS technology holds potential to be effective screening tool for pancreatic cancer
November 17, 2017 - Applying AFM to study the viscoelastic properties of cells
November 17, 2017 - FDA Alert: Nexterone (amiodarone HCl) 150 mg/100 mL Premixed Injection: Recall
November 17, 2017 - High cognitive ability not a safeguard from conspiracies, paranormal beliefs
November 17, 2017 - Computerized speed of processing training results in decreased risk of dementia
November 17, 2017 - Sexual activity poses exceedingly small risk in causing sudden cardiac arrest
New instructional find out about unearths true extent of the hyperlink between onerous water and eczema

New instructional find out about unearths true extent of the hyperlink between onerous water and eczema

image_pdfDownload PDFimage_print
Credit score: CC0 Public Area

Onerous water damages our protecting pores and skin barrier and may give a contribution to the improvement of eczema, a brand new find out about has proven.

Researchers from the College of Sheffield and King’s Faculty London have found out that exposing the outside to onerous water damages the outside barrier – which is our defence towards outdoor threats comparable to micro organism or solar burn – and will increase the sensitivity of the outside to attainable irritants present in on a regular basis wash merchandise comparable to cleaning soap or washing powder.

Onerous water comprises prime ranges of calcium and magnesium ions that bind to surfactants comparable to sodium lauryl sulfate (SLS) and sodium lauryl ether sulfate (SLES) – which act as detergents or wetting brokers – making them insoluble, so that they precipitate onto the outside.

Pores and skin pH is usually acidic however onerous water has prime alkalinity this means that it will possibly elevate the outside floor pH. A shift in opposition to alkaline pH disturbs the outside’s herbal serve as as a bodily barrier and leaves it liable to colonization by way of doubtlessly pathogenic micro organism which will motive an infection.

Lead creator of the find out about, Dr Simon Danby from the College of Sheffield’s Division of An infection, Immunity and Cardiovascular Illness, mentioned: “Via harmful the outside barrier, washing with onerous water might give a contribution to the improvement of eczema – a prolonged pores and skin situation characterized by way of an intensely itchy pink rash.

“Sufferers with eczema are a lot more delicate to the consequences of onerous water than other people with wholesome pores and skin. This build up in sensitivity is related to a genetic predisposition to a pores and skin barrier defect led to by way of mutations within the gene encoding filaggrin. Filaggrin is a structural protein essential for the formation of our pores and skin’s barrier to the outdoor setting. As much as part of all other people with eczema lift a filaggrin gene.”

Credit score: College of Sheffield

“This new find out about unearths the mechanism in which calcium and magnesium ions in onerous water, surfactants, and filaggrin engage to break the outside barrier unlocking new details about how publicity to onerous water may doubtlessly give a contribution to the improvement of eczema.”

Signs of eczema (also referred to as ‘atopic eczema’ or ‘atopic dermatitis’) come with infected, dry pores and skin and continuously secondary pores and skin infections, which will have an effect on any a part of the frame and each side of an individual’s lifestyles – each bodily and emotionally.

The brand new find out about, which Harvey Water Softeners was once requested to fund, was once revealed this week (16 September 2017) within the Magazine of Investigative Dermatology. The workforce of researchers tested whether or not getting rid of the calcium and magnesium ions the use of an ion-exchange water softener may mitigate the uncomfortable side effects of onerous water at the pores and skin. They discovered that the use of a water softener reduces the dangerous results of surfactants, doubtlessly lowering the chance of creating eczema.

Managing director of Harvey Water Softeners, Martin Hurworth, mentioned: “The hyperlink between onerous water and eczema has been reported anecdotally for years – now for the primary time there is instructional evidence. We have been happy to offer business improve to this find out about within the type of onerous water samples and the twin-cylinder water softeners that equipped the softened water that was once wanted.”

Co-senior creator of the find out about, Dr Carsten Flohr from the St John’s Institute of Dermatology at Man’s and St Thomas’ NHS Basis Accept as true with and King’s Faculty London, mentioned: “One in 5 kids and one in 12 adults in the United Kingdom be afflicted by eczema, costing the NHS smartly over £500 million once a year.

“It’s all through the primary few days and months of lifestyles that our pores and skin is maximum prone to harm and maximum susceptible to creating eczema.

“For this reason we at the moment are embarking on a pilot trial to analyze whether or not set up of a home water softener across the time of beginning can save you pores and skin barrier breakdown and eczema in the ones residing in onerous water spaces.”


Discover additional:
Onerous water related to possibility of eczema in babies

Additional info:
The Impact of Water Hardness on Surfactant Deposition Following Washing an Next Pores and skin Inflammation in Atopic Dermatitis Sufferers and Wholesome Controls. Magazine of Investigative Dermatology. DOI: 10.10.16/j.jid2017.08.037

Magazine reference:
Magazine of Investigative Dermatology

Supplied by way of:
College of Sheffield

Tagged with:

About author

Related Articles