Breaking News
March 20, 2018 - Stem cell treatment may help rejuvenate ovaries, avoid effects of premature menopause
March 20, 2018 - FDA Approves Hizentra (Immune Globulin Subcutaneous [Human] 20% Liquid) for the Treatment of Patients With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
March 20, 2018 - Death Strikes Young in RA
March 20, 2018 - Quiescent cells also mutate
March 20, 2018 - Stem cell-derived ocular cells treat severe AMD
March 20, 2018 - Mediterranean diet appears to be good for postmenopausal women’s bones and muscles
March 20, 2018 - Scientists discover rare childhood liver cancer’s ability to metastasize to the brain
March 20, 2018 - Treating metastatic breast cancer with immunotherapy
March 20, 2018 - The 5:2 diet could have beneficial impact on important risk markers for cardiovascular disease
March 20, 2018 - Neanderthals Just Part of the Evolutionary Puzzle
March 20, 2018 - Higher Mortality With Surgery for Early NSCLC
March 20, 2018 - Researchers go skin deep to explore what causes wrinkles
March 20, 2018 - E-cigarette use linked to fat accumulation in the liver
March 20, 2018 - Fearful worms provide new clues about human anxiety
March 20, 2018 - Oral micronized progesterone may reduce hot flashes, night sweats in perimenopausal women
March 20, 2018 - Newer treatment for type 2 diabetes reduces liver fat in patients with NAFLD
March 20, 2018 - I.D. Break: PrEP Map; Faulty Flu Meds; Better Zika Test?
March 20, 2018 - Bronchial thermoplasty can improve severe asthmatic cough
March 19, 2018 - Speeding up wound healing using nanofiber dressings
March 19, 2018 - Summit Announces New Analysis Showing Ezutromid Significantly Reduced Muscle Inflammation in Phase 2 Clinical Trial in DMD
March 19, 2018 - Optimizing Sham Acupuncture: That’s Improbable!
March 19, 2018 - Women who have gestational diabetes in pregnancy are at higher risk of future health issues
March 19, 2018 - Viagra cuts colorectal cancer risk in animal model
March 19, 2018 - Vitamin B12 supplementation could postpone disease progression in Parkinson’s patients
March 19, 2018 - Study shows that omega-6 fatty acids could protect against premature death
March 19, 2018 - TherapeuticsMD Announces FDA Acceptance of New Drug Application (NDA) and Prescription Drug User Fee Act (PDUFA) Date for TX-001HR
March 19, 2018 - Minorities More Sensitive To Pain? Pain Medicine News Report
March 19, 2018 - Low blood sugar poses unaddressed threat to people with type 2 diabetes
March 19, 2018 - ACEA goes live with exhaustive, searchable library of NovoCyte publications
March 19, 2018 - Consumption of low-calorie sweeteners could promote metabolic syndrome, increase diabetes risk
March 19, 2018 - Wearable medical patch shows promise for early detection of hypoglycemia in type 1 diabetes
March 19, 2018 - High-energy breakfast leads to better diabetes control and weight loss
March 19, 2018 - D.C. Week: Community Health Centers Get Azar’s Love
March 19, 2018 - Younger siblings of SIDS victims have four-fold increased risk of sudden death
March 19, 2018 - Toothpaste alone does not prevent dental erosion or hypersensitivity
March 19, 2018 - Discovery aids understanding of amyotrophic lateral sclerosis
March 19, 2018 - Hormone imbalance may be reason for higher diabetes rates among men with insufficient sleep
March 19, 2018 - Docs worry there’s ‘nowhere to send’ new and expectant moms with depression
March 19, 2018 - Obesity linked to increased DNA damage in breast epithelium of BRCA mutation carriers
March 19, 2018 - Heart rate increases with higher alcohol consumption
March 19, 2018 - Template produced for clinically validated DIY stethoscope
March 19, 2018 - Experts highlight nocturia as most common cause of poor night’s sleep
March 19, 2018 - Fit Middle-Aged Women May Fend Off Dementia Later
March 19, 2018 - Fake Insta Doc; Humana’s Weird Pay Bump Tax Trick; Few NPDB Searches
March 19, 2018 - Guidelines for fluoride intake—are they appropriate?
March 19, 2018 - Race and pre-pregnancy BMI may be key predictors of maternal weight gain
March 19, 2018 - Telediabetes program improves blood sugar control for veterans
March 19, 2018 - Research suggests breastfeeding as protective factor against obesity in high-birthweight infants
March 19, 2018 - Morning Break: House Nixes ‘Right-to-Try’ Bill; Purdue’s PR Makeover; Air in the Brain
March 19, 2018 - Heart researchers develop a new, promising imaging technique for cardiac arrhythmias
March 19, 2018 - Mice study shows how BPA exposure during pregnancy can lead to altered brain development
March 19, 2018 - Breastfeeding mothers who overeat may increase risk of health problems in offspring
March 19, 2018 - New mobile application can detect atrial fibrillation that causes strokes
March 19, 2018 - Study finds low rates of preconception counseling among women of childbearing age with diabetes
March 19, 2018 - Vitl Life Science Solutions announces launch of new Lu-mini at analytica 2018
March 19, 2018 - ObsEva SA Reports Positive Topline Results from IMPLANT2 Phase 3 Clinical Trial of Nolasiban in IVF
March 19, 2018 - D.C. Week: States Plead for Federal $$ in Opioid Fight
March 19, 2018 - Polycystic ovary syndrome – Genetics Home Reference
March 19, 2018 - Reducing co-payments improves patient, physician adherence to guideline-recommended treatment post-MI
March 19, 2018 - Normalizing estrogen levels can benefit female athletes with irregular menstrual periods
March 19, 2018 - Fitness trackers and virtual coaches motivate patients to exercise post cardiac rehab
March 19, 2018 - Atrial fibrillation patients could reduce risk of dementia by taking stroke prevention drugs
March 19, 2018 - Low sperm count more prevalent with other health problems finds study
March 19, 2018 - Male birth control pill taken once a day shows success
March 19, 2018 - AcelRx Announces Receipt of Type A FDA Meeting Minutes and Plans to Resubmit the DSUVIA New Drug Application in Q2 2018
March 19, 2018 - Eye Docs Adopt EHRs Despite Reservations
March 19, 2018 - CRISPR enhances cancer immunotherapy
March 19, 2018 - Study finds first evidence of delayed aging among Americans
March 19, 2018 - Aussies unaware of sun protection rules to prevent skin cancer
March 19, 2018 - Essential oils linked to abnormal breast development in boys
March 19, 2018 - ‘Tummy Tuck’ Relieved Postpartum Back Pain/Incontinence
March 19, 2018 - New biomarkers for neuroblastoma, a type of cancer in children
March 19, 2018 - Hookah Smoking Carries a Poisoning Risk
March 19, 2018 - Do Mood and Anxiety Affect MS Disability?
March 19, 2018 - Mean depth of ultrasonographic penetration greater in autism
March 19, 2018 - Platypus milk may help combat antibiotic resistance
March 19, 2018 - U.S. IDE study of THERMOCOOL SMARTTOUCH SF Catheter completes patient enrollment
March 18, 2018 - E-cigarette use exposes adolescents to potentially cancer-causing chemicals
March 18, 2018 - GOP Senator: Solve Opioid Crisis Through Community, Not Policy
March 18, 2018 - Why is ADHD more common in boys than girls?
New process lets in surgeons to reconstruct complete coronary heart valves from affected person’s personal tissue

New process lets in surgeons to reconstruct complete coronary heart valves from affected person’s personal tissue

image_pdfDownload PDFimage_print

A brand new manner lets in surgeons to reconstruct complete coronary heart valves from the affected person’s personal tissue. This surgical process is lately handiest used at a handful of facilities on the planet. Lately, PD Dr. Markus Krane, Deputy Director of the Cardiovascular Surgical treatment Division of the German Middle Centre Munich, has extensively utilized the brand new manner on sufferers in Munich. The process is especially tremendous for kids and younger sufferers.

The guts steadily pumps oxygen-rich blood from the lungs, throughout the aorta and into the frame. The aortic valve acts as a security valve, fighting blood from flowing again into the cardiac ventricle. It is composed of 3 cusps hooked up to a valve ring. In sufferers with a congenital defect, an an infection on the coronary heart valve or, maximum frequently, a narrowing, the valve is not in a position to serve as reliably and needs to be changed. Since November 2016, the Division of Cardiovascular Surgical treatment of the German Middle Centre Munich has been pioneering a brand new surgical approach to exchange the valve.

“We realized the process from Professor Shigeyuki Ozaki from Japan, who advanced and standardized it. On this manner, a brand new valve is shaped from the affected person’s personal frame tissue. The way overcomes many issues that used to bedevil the valve-replacement process, particularly in kids and younger sufferers,” explains Professor Rüdiger Lange, Director of the Division of Cardiovascular Surgical treatment of the German Middle Centre Munich and Professor for Cardiovascular Surgical treatment on the Technical College of Munich (TUM).

Longer lifestyles span and not more anticoagulant

Within the standard way, sufferers obtain both a man-made valve product of titanium or a organic valve from a cow or pig. Alternatively, each strategies have disadvantages. When it comes to the steel valve, the affected person should be placed on long-term anticoagulant medicine to stop blood clots from forming at the implant. Even small wounds then turn out to be problematic for the affected person, because the blood coagulates extra slowly than standard.

The downside of bovine or porcine valves is that they just have a lifestyles span of 10−15 years, and then they should get replaced. In truth, the lifestyles span may also be considerably shorter in kids and younger adults with a congenital valve defect because of larger mechanical tension. In consequence, sophisticated open-heart surgical operation should be repeated over and over.

The researchers are assured that the valves which can be reconstructed from the affected person’s personal tissue the use of the Ozaki manner are a lot more sturdy. “The valve is constructed up at the affected person’s herbal valve ring. Because of this we don’t require a man-made prosthetic ring, which is mounted and immovable. Consequently, the mechanical houses of a herbal coronary heart valve are in large part retained. As well as, it’s not important to manage anticoagulants after the operation,” says Dr. Markus Krane, enumerating the benefits of the brand new manner.

A cross-sectional template for the brand new aortic valve

Within the Ozaki manner, the previous faulty aortic valve is first utterly got rid of, and the herbal aortic valve ring is wiped clean. Because the human aortic valve is composed of 3 cusps, those 3 components should even be reconstructed from the affected person’s pericardium, the membrane enclosing the guts. Markus Krane gets rid of a sufficiently massive piece from the pericardium, which is then used as subject matter for the brand new valve. This isn’t an issue, because the ensuing hole is roofed on the finish of the operation with a work of artificial pericardium.

Ahead of the surgeon can use the got rid of pericardial tissue to reconstruct the aortic valve, it should first be handled. “The tissue continues to be very cushy after it’s been got rid of. So as so to use it as a difficult, powerful valve, we need to tan it by way of a procedure similar to the process used for making ready leather-based,” Krane explains. As each and every affected person has a distinct valve measurement, the surgeons measure the previous valve cusps and minimize new cusps from the got rid of piece of pericardium the use of a bespoke template. The brand new cusps are then sutured onto the herbal valve ring within the affected person’s coronary heart.

Krane has already used the brand new manner on over 40 sufferers – up to now with none headaches. The researchers are lately carrying out a medical trial with over 100 sufferers which can run till 2019. They wish to decide whether or not the brand new way is awesome to the traditional manner of changing a valve with a man-made prosthesis. “We’re seeking to display how neatly the Ozaki manner works. Possibly extra medical doctors around the globe will then get started the use of it,” Krane says. Lately, he presented the process to a number of Russian medical doctors with the outcome that they have got now additionally followed the Ozaki manner.


Tagged with:

About author

Related Articles