Breaking News
October 21, 2017 - New Genes Linked to Restless Legs Syndrome
October 21, 2017 - No relief in sight for those suffering from sciatica
October 21, 2017 - 'This Is About Saving Lives': What We Heard This Week
October 21, 2017 - 3 Million Americans Say They Carry Handguns Every Day
October 21, 2017 - Night shift work linked to an increased risk of obesity
October 21, 2017 - Avoiding Alcohol Helps the Heart Beat Better
October 21, 2017 - Exposure to heavy metals may increase risk of autism
October 21, 2017 - Derms: Oral Contraceptives as Acne Tx Warrant Caution
October 21, 2017 - How Foods Labeled 'Healthy' Can Still Make You Fat
October 21, 2017 - ALS patient behind ice bucket challenge: I will bounce back
October 21, 2017 - FDA Advisory Committee Unanimously Recommends Approval of Investigational Luxturna (voretigene neparvovec) for Patients with Biallelic RPE65-mediated Inherited Retinal Disease
October 21, 2017 - Household bleach may raise chronic lung disease risk
October 21, 2017 - Patient Care vs Primary Care: Is There a Problem Here?
October 21, 2017 - State Laws Help Reduce Concussions in Youth Sports
October 21, 2017 - Study indicates proof of concept for using a surrogate liquid biopsy to provide genetic profile of retinoblastoma tumors
October 21, 2017 - Story-based videos hold promise for encouraging Latinas to seek help for anxiety and depression
October 21, 2017 - Study identifies predictors of poor outcomes in Duchenne muscular dystrophy patients
October 21, 2017 - New study explores how herpes simplex virus may change during familial transmission
October 21, 2017 - Researchers analyze frequency of mislabeling in herbal and dietary supplements
October 21, 2017 - Direct‐acting antiviral therapy linked to 71% reduction in liver cancer risk
October 21, 2017 - NAFLD linked to higher cardiovascular risk in women, but not in men
October 21, 2017 - Study finds increasing health care costs for patients with alcoholic cirrhosis
October 21, 2017 - Liver cirrhosis mortality found to be greater than that of five major cancers
October 21, 2017 - VUMC reaches new milestone after performing 2,000th liver transplant
October 21, 2017 - Study examines risk of using liver organs from hepatitis C positive donors
October 21, 2017 - Daily aspirin therapy linked to reduced risk of HBV‐related liver cancer
October 21, 2017 - Increased use of split liver transplantation could decrease pediatric waitlist deaths
October 21, 2017 - HCV screening or diagnosis could lower non‐prescribed opioid use
October 21, 2017 - Schizophrenia Affects Brain's Communication Network
October 21, 2017 - Serum metabolites linked to NAFLD may be heritable, research shows
October 21, 2017 - Pneumoconiosis: Symptoms, risk factors, and management
October 21, 2017 - Study finds rise in pregnancy rates among women with chronic liver disease
October 21, 2017 - 1 in 5 Young Women Who Tan Indoors Get Addicted
October 21, 2017 - Stent Outcomes Not So Different Across Sexes, Races
October 21, 2017 - Eyebank corneal tissue prep may increase infection risk
October 21, 2017 - Researchers use nanopore technique to detect biomarkers of disease
October 21, 2017 - UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs
October 21, 2017 - Umass Amherst scientist receives grant to study pollutant effects on embryos in animal models
October 21, 2017 - Study finds rising incidence of IBD in newly industrialized countries
October 21, 2017 - Researchers use novel imaging technique for precise assessment of spinal degeneration
October 21, 2017 - Penn State receives federal grant to improve services for children with complex communication needs
October 21, 2017 - New synthetic genetic tool measures and manipulates protein aggregation in live cells
October 21, 2017 - Introduction of childbirth guide results in fewer stillbirths at East African hospital
October 21, 2017 - New vaccine for pneumonia holds promise to save thousands of lives
October 21, 2017 - Study provides deeper understanding on mechanisms of lipid-based autoimmune disease
October 21, 2017 - Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation
October 20, 2017 - Parents with alcohol use disorder increase risk for teen dating violence
October 20, 2017 - Inventiva’s Phase IIb FASST Trial in Systemic Sclerosis with Lanifibranor Completes Enrollment
October 20, 2017 - Torn meniscus: Causes, symptoms, and recovery
October 20, 2017 - Post-Mastectomy Breast Reconstruction Gains Ground
October 20, 2017 - Self-Harm on the Rise Among Teen Girls
October 20, 2017 - Mice delivered by C-section gain more weight than those delivered naturally
October 20, 2017 - Novo Nordisk Receives Positive 16-0 vote from FDA Advisory Committee in Favor of Approval for Semaglutide
October 20, 2017 - Shy bladder: Causes and treatments
October 20, 2017 - Obese Kids with Asthma at Higher Risk for Hospital Readmission
October 20, 2017 - Could Too Much Exercise Be Bad for Men's Hearts?
October 20, 2017 - Oxidative stress produces damage linked with increased risk of preterm birth
October 20, 2017 - Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests
October 20, 2017 - Health Tip: Best Grains And Starchy Veggies for Diabetics
October 20, 2017 - Alzheimer's could be diagnosed early with sniff tests
October 20, 2017 - CardioBrief: Imaging Offers Insight Into Inflammation in CV Disease
October 20, 2017 - More Young Kids Spending Lots of Time on Phones, Tablets
October 20, 2017 - Study provides insights into how amygdala regulates emotions and social behavior
October 20, 2017 - Chromosomes may be entangled, research finds
October 20, 2017 - Experts create quality improvement blueprint to reduce repetitive lab tests for hospitalized patients
October 20, 2017 - Researchers discover new function in gene-regulatory protein
October 20, 2017 - Findings suggest e-cigarettes may be just as bad as traditional cigarettes
October 20, 2017 - Adipose-derived stem cell clinical trial focuses on non-healing leg wounds
October 20, 2017 - Incysus Announces FDA Approval of IND Application for a Phase I Study of a Gamma-Delta (γδ) T Cell Leukemia and Lymphoma Immunotherapy
October 20, 2017 - Dust mite allergy: Symptoms, treatment, and prevention
October 20, 2017 - FDA's Patient Engagement Committee Launches
October 20, 2017 - Arthritis Can Strike Children
October 20, 2017 - Study shows people find well-being more so from special places than from mementoes
October 20, 2017 - Suspected plague cases from Seychelles tested negative at WHO partner laboratory
October 20, 2017 - UGA researchers pinpoint factors that drive sharp rise in breast cancer genetic testing
October 20, 2017 - New study reveals extensive healthcare costs that result from acute kidney injury
October 20, 2017 - Amid for-profit surge, rural hospice has offered free care for 40 years
October 20, 2017 - Teens' increased use of electronic devices linked to rise in insufficient sleep
October 20, 2017 - Delayed word processing could indicate MCI patients’ likelihood of developing Alzheimer's
October 20, 2017 - Researchers reveal how certain nerves sustain prostate cancer growth
Fertility Tests May Not Be Best Gauge of Your Biological Clock

Fertility Tests May Not Be Best Gauge of Your Biological Clock

image_pdfDownload PDFimage_print

HealthDay news image

TUESDAY, Oct. 10, 2017 (HealthDay News) — Women in their 30s and early 40s who want to know whether their biological clocks are running out should skip fertility testing, a new study suggests.

Fertility clinics commonly use blood and urine tests to assess the quantity and quality of eggs remaining in a woman’s ovaries — information that clinicians can use in making decisions about treating infertile women.

However, a study in the Oct. 10 issue of the Journal of the American Medical Association found that these tests cannot predict whether a woman in her later reproductive years will get pregnant naturally.

“We were hoping to see that these biomarkers would predict a woman’s ability to get pregnant, but we didn’t find that,” said Dr. Anne Steiner, the study’s lead author.

Steiner, a professor of obstetrics and gynecology at the University of North Carolina, Chapel Hill, said there’s “huge interest” in such a fertility test.

Women generally have more trouble getting pregnant as they age. The egg supply dwindles later in life, and the quality of the remaining eggs declines. As a result, Steiner explained, women often want assurance that there’s still time to start a family or confirmation that they should freeze their eggs for a future pregnancy.

The age at which a woman can no longer conceive varies from person to person. About one-third of couples will have trouble getting pregnant if the female is 35 or older, according to the American Society for Reproductive Medicine.

Low levels of anti-mullerian hormone (AMH) and high levels of follicle-stimulating hormone (FSH) are considered indicators of low “ovarian reserve,” meaning that a woman has fewer available eggs. That has fueled women’s interest in having blood and urine tests done during annual checkups to monitor their fertility. It’s also fueled a market for over-the-counter urine tests that measure FHS.

Consumers may pay well over $100 for FSH testing, depending on where the test is performed and other variables, according to Healthcare Bluebook, which tracks health care cost and quality data. That doesn’t include the cost of the physician office visit. A “fair price” is about $49, according to the company’s consumer website.

Blood collection and analysis can run from $80 to about $200, Steiner estimated.

Do-it-yourself test kits also are available. One online retailer listed two urine test sticks for $20.

But do blood and urine tests provide an accurate window into a woman’s ability to conceive?

To find out, Steiner and her colleagues recruited women 30 to 44 years old with no known history or risk factors for infertility who were just starting to try to get pregnant. The investigators took their blood and urine samples and followed them for a year to see whether the women conceived.

As expected, AMH levels decreased and FSH levels increased with age. But after accounting for age, women with low ovarian reserve were just as likely to get pregnant as were those with normal values.

Thomas Price, a Duke University obstetrician/gynecologist and president of the Society for Reproductive Endocrinology and Fertility, said that “these tests are very good at predicting how many eggs a woman is going to make with injectable fertility drugs.”

But, Steiner added, these tests cannot be recommended as a predictor of natural pregnancy.

“Age should really be the driver in their reproductive plans, not these biomarker values,” she said.

SOURCES: Anne Steiner, M.D., professor, reproductive endocrinology and fertility, University of North Carolina, Chapel Hill; Thomas Price, M.D., professor, obstetrics and gynecology, division of reproductive endocrinology and infertility, Duke University, Durham, N.C.; American Society for Reproductive Medicine, Washington, D.C.; Oct. 10, 2017, Journal of the American Medical Association

News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services.

Tagged with:

About author

Related Articles