Breaking News
April 20, 2018 - College students with autism have high rate of suicidal thoughts
April 20, 2018 - Study sheds light on how the HSC niche is maintained
April 20, 2018 - Drug test spurs frank talk between hypertension patients and doctors
April 19, 2018 - Low-cost deworming drug improves female farmers’ physical fitness
April 19, 2018 - Genome editing identifies neural circuit behind leptin’s anti-obesity and anti-diabetes effects
April 19, 2018 - Many European countries lack comprehensive policy to eliminate viral hepatitis
April 19, 2018 - Young people with ADHD ‘more likely’ to come from deprived neighbourhoods
April 19, 2018 - SLU professor discovers new biomarkers for chlorine gas exposure
April 19, 2018 - Study proposes new mechanism that may contribute to gender differences in weight control
April 19, 2018 - Sleep restriction therapy does not interfere with insomnia patient’s driving ability, research shows
April 19, 2018 - Deep brain stimulation offers relief to UTHealth patient with treatment-resistant depression
April 19, 2018 - Study shows fatty fish and camelina oil boost HDL and IDL cholesterol
April 19, 2018 - FDA Alert: Euphoric Capsules by Epic Products: Recall
April 19, 2018 - Researchers identify peptide produced during cartilage deterioration as a potential source of osteoarthritis pain
April 19, 2018 - New breakthrough may allow scientists to orchestrate tissue regeneration in humans
April 19, 2018 - SYGNIS AG introduces new TruePrime apoptotic cell free DNA amplification kit
April 19, 2018 - Innovative device shows promise in capturing and releasing circulating tumor cells
April 19, 2018 - Researchers shed light on role of striosomal neurons in reinforcement learning
April 19, 2018 - Genetic make-up impacts long-term effectiveness of phobia treatment
April 19, 2018 - Novel biomarker can distinguish malignant lung nodules
April 19, 2018 - Study reports promising novel approach to treat therapy resistant pediatric brain tumors
April 19, 2018 - One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy
April 19, 2018 - Hydroxychloroquine no more effective than placebo for relieving osteoarthritis hand pain
April 19, 2018 - Transplanted livers have a protective effect and reduce potential for organ rejection
April 19, 2018 - Researchers develop new method to study activity of inflammatory cells
April 19, 2018 - Researchers discover highly antibiotic resistant superbugs in Gulf States
April 19, 2018 - Interaction between dioxin and HLA gene variant activates events associated with rheumatoid arthritis
April 19, 2018 - Eyes of adolescents could be associated with increased risk of cardiovascular disease in later life
April 19, 2018 - U.S. Women Less Likely Than Men to Get Statins After Heart Attack
April 19, 2018 - Health Canada grants cannabis cultivation license to High Park Farms
April 19, 2018 - Atypical brain development observed in preschoolers with ADHD symptoms
April 19, 2018 - SC Johnson releases annual Sustainability Report
April 19, 2018 - Positive attitudes about aging reduce risk of dementia in older adults
April 19, 2018 - Environmental pollutants found to worsen rheumatoid arthritis
April 19, 2018 - UT Southwestern scientists discover protein linked to metastatic breast cancer
April 19, 2018 - Study highlights need for further evidence to improve symptom management in end of life care
April 19, 2018 - Detecting diminished dopamine-firing cells inside brain could reveal earliest signs of Alzheimer’s
April 19, 2018 - Uniqsis offers high-power LED light unit for scalable flow photochemistry reactions
April 19, 2018 - Case study shows how intravascular ultrasound imaging helps detect acute aortic syndrome
April 19, 2018 - Research reveals new mechanism by which HIV evades the immune system
April 19, 2018 - Nanodisc-delivered cancer treatment helps eliminate tumors
April 19, 2018 - Functional connectivity MRI could help detect brain disorders and diseases
April 19, 2018 - Finding better way to quantify neuropathy symptoms and treatment efficacy
April 19, 2018 - Study examines effectiveness of caregiver education about sickle cell trait
April 19, 2018 - High-resolution images of tumor vasculature using new technology
April 19, 2018 - Lack of sleep may be linked to risk factor for Alzheimer’s disease
April 19, 2018 - Study finds neurotransmitter may play a role in alcohol relapse, addiction
April 19, 2018 - Researchers build molecular networks of calcific aortic valve disease
April 19, 2018 - Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens
April 19, 2018 - Scientists decipher mechanism of chemotherapy induced female infertility
April 19, 2018 - New insight may allow researchers to design drugs that improve immune responses to vaccines
April 19, 2018 - FDA Approves Crysvita (burosumab-twza) for X-Linked Hypophosphatemia
April 19, 2018 - Researchers uncover origin of virus-fighting plasma B cells
April 19, 2018 - Study finds no evidence of lower intelligence in young children who had anesthesia
April 19, 2018 - Baboons break out of research facility briefly
April 19, 2018 - Study shows how deployment time increases risk of suicide attempt in soldiers
April 19, 2018 - Specific odors from malaria infected individuals attract more mosquitoes
April 19, 2018 - FDA Alert: Rhino 69 Extreme 50000 by AMA Wholesale: Recall
April 19, 2018 - Top HIV cure research team refutes major recent results on how to identify HIV persistence
April 19, 2018 - Experts propose new solutions to increase benefit, affordability of targeted cancer medicines
April 19, 2018 - Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice
April 19, 2018 - New machine learning method offers better way to detect heart disease
April 19, 2018 - CNIO researchers determine structure of protein complex related to cell survival
April 19, 2018 - Faith-based diabetes support program launched by UTSA research team
April 19, 2018 - Volumetric Laser Endomicroscopy Helps ID Barrett’s Regions
April 19, 2018 - Engineered cartilage template to heal broken bones
April 19, 2018 - New computational framework accurately predicts drug-drug and drug-food interactions
April 18, 2018 - Some human cancers may be result of evolutionary accidents, research finds
April 18, 2018 - Higher levels of education linked to lower dementia risk in older African Americans
April 18, 2018 - Smoking Puts Blacks at Higher Risk for Heart Failure
April 18, 2018 - Physiotherapist contributes to guidelines for knee cartilage treatment
April 18, 2018 - Researchers use ‘top-down proteomics’ strategy to get new insights into cancer
April 18, 2018 - Physician assistants less likely to accurately diagnose early stage skin cancers
April 18, 2018 - New faster, streamlined method for bowel cancer detection and treatment
April 18, 2018 - Researchers identify new Listeria species in Costa Rica
April 18, 2018 - Novel interactive diagram shows many facets of mild traumatic brain injury
April 18, 2018 - Short sleep linked to obesity in children and adolescents
April 18, 2018 - When weight loss helps with sleep
April 18, 2018 - New mathematical model can predict efficiency of microbiome therapies
April 18, 2018 - People with high LDL cholesterol levels likely to get greater benefits from statins
Russian researcher determined range of reference values for boron in the human body

Russian researcher determined range of reference values for boron in the human body

image_pdfDownload PDFimage_print

Researcher from the RUDN University (Russia), together with his colleagues from Croatia, determined the range of reference values for boron in the tissues of human body. This study will provide a better understanding of the role that this important trace element plays in metabolism. The results of the work were presented in the Journal of Trace Elements in Medicine and Biology.

Trace elements (substances essential for the life of plants and animals, but present in the organism only in microscopic amounts) play an important role in the metabolism. Until recently, boron was not considered to be an essential trace element for humans. However, a number of recent studies have emphasized the importance of boron. It has a number of useful biochemical functions, plays an important role in bone metabolism and vitamin D metabolism. In many instances, boron does this by being an essential co-partner with other substances to fine-tune many human physiologic interactions. Also, some recent studies have shown that boron regulates the action of parathyroid hormone (a substance secreted by the parathyroid glands regulates the level of calcium and phosphorus in the blood).

“In order to diagnose and correct the exchange of boron in humans, you need to know the norms of its concentration in the body. Then it will be clear if there is a shortage of boron, or, on the contrary, it is in excess. To establish these boundaries, our work was started,” — co-author of the article Andrei Grabeklis (RUDN University) explained.

Almost all boron usually enters the human body in an alimentary way (with food). The purpose of this study was to establish adequate reference range of boron concentration in hair and whole blood. These two “carriers” are different in their indicators: in the blood, the content of all substances is maintained within strict limits, and any deviations indicate either short-term changes (e.g, a half-hour ago a person ate a dish with a high boron content), or serious health issues. In the hair, substances are washed out from blood and accumulate there gradually (as the hair grows). Therefore, this indicator allows scientists to track what has been ingested in the body over a long period of time.

Hair boron was analyzed in a random sample of 727 apparently healthy adults (263 Men, 464 Women). Whole blood was analyzed in a subset of 212 subjects (152 women and 80 men); the median age of women and men was 47 and 41.5 years, respectively. The cohort consisted of subjects from the general Croatian population who were interested to learn about their health status; the majority of them were living in the capital city region of Zagreb, Croatia. All the subjects were fed their usual home prepared mixed mid-European diet, and none of them have reported an adverse medical health condition.

Hair boron and whole blood boron were then analyzed with the inductively coupled plasma mass spectrometry (ICP-MS) at the Center for Biotic Medicine (CBM), Moscow, Russia. The CBM is an ISO Europe certified commercial laboratory for analyzing bioelements (macro elements, trace elements, and ultratrace elements) in different biological matrices.

It was established that the adequate reference range for hair boron concentration was (μg · g-1) 0.77-6.51 for men and distinctly lower 0.47-3.89 for women. There was no detectable difference in the whole blood boron for the adequate reference range between men (0.020-0.078 μg · ml-1) and women (0019-0.062).

According to scientists, these results indicate that the nature of boron metabolism in the human body is not gender-dependent, and its functions are the same for men and women. At the same time, the dietary balance of boron is different in men and women, most likely due to different patterns of food consumption.

Tagged with:

About author

Related Articles