Breaking News
December 14, 2018 - Scientists perform lung lavage as new approach for tuberculosis diagnosis in rhinoceros
December 14, 2018 - Recent winners of the Nobel Medicine Prize
December 14, 2018 - KHN’s ‘What the Health?’ Insurance enrollment is lagging — and there are lots of reasons why
December 14, 2018 - Study assesses safety and efficacy of new treatment for pancreatic cancer
December 14, 2018 - Study finds drug targets for Ebola, Dengue, and Zika viruses
December 14, 2018 - Study highlights need for personalized approach to treat ICU acquired delirium
December 14, 2018 - Massage helps relieve pain, improve mobility in patients with knee osteoarthritis
December 14, 2018 - Average outpatient visit in the U.S. costs nearly $500, shows new study
December 14, 2018 - Reference Infliximab, Biosimilar Equivalent for Crohn’s Disease
December 14, 2018 - New contact lens to treat eye injuries
December 14, 2018 - Acne could have a genetic basis find researchers promising new cure
December 14, 2018 - Higher physical activity associated with improved mood
December 14, 2018 - New UGA study points to optimal hypertension treatment for stroke patients
December 14, 2018 - Study highlights factors that can reduce food cravings
December 14, 2018 - Researchers discover Ebola-fighting protein in human cells
December 14, 2018 - Fentanyl surpasses heroin in cause of U.S. drug overdose deaths
December 14, 2018 - When Heart Attack Strikes, Women Often Hesitate to Call for Help
December 14, 2018 - A warning about costume contacts
December 14, 2018 - Study examines link between peripheral artery disease and heart attack
December 14, 2018 - Researchers develop biotechnological tool to produce antifungal proteins in plants
December 14, 2018 - 3D-printed adaptive aids can benefit patients with arthritis
December 14, 2018 - Chronic bullying during adolescence impacts mental health
December 14, 2018 - Integral Molecular and Merus collaborate to develop bispecific antibody therapeutics
December 13, 2018 - Importance of cell cycle and cellular senescence in the placenta discovered
December 13, 2018 - Gold “nanoprisms” open new window into vessels and single cells
December 13, 2018 - Research findings could lead to new targets for cancer-fighting therapeutics
December 13, 2018 - Butantan Institute signs collaboration agreement with MSD to develop dengue vaccines
December 13, 2018 - Study explores how patients want to discuss symptoms with doctors
December 13, 2018 - RUDN medics first to gather scattered data on hepatitis morbidity in Somalia
December 13, 2018 - Age and gender disparities found in use of bed nets to prevent malaria in sub-Saharan Africa
December 13, 2018 - Caffeine therapy benefits developing brains of premature babies
December 13, 2018 - New review focuses on electrospinning techniques used in musculoskeletal tissue engineering
December 13, 2018 - A new division focused on human immune system
December 13, 2018 - Zogenix Announces Positive Phase 3 Trial Results on the Efficacy and Safety of Fintepla (ZX008) in Dravet Syndrome
December 13, 2018 - BCR ABL Genetic Test: MedlinePlus Lab Test Information
December 13, 2018 - Caffeinated beverages during pregnancy linked to lower birth weight babies
December 13, 2018 - Stanford Medicine Health Trends Report examines opportunity to democratize health care
December 13, 2018 - Obsessive-compulsive disorder may protect individuals from obesity
December 13, 2018 - Scientists investigate how a painful event is processed in the brain
December 13, 2018 - Genetic study reveals new insights into underlying causes of moderate-to-severe asthma
December 13, 2018 - Study uncovers new genetic clues to frontotemporal dementia
December 13, 2018 - Vitamin C supplementation for pregnant smokers may reduce harm to infants’ lungs
December 13, 2018 - New study reveals yin-yang personality of dopamine
December 13, 2018 - Research identifies nerve-signaling pathway behind sustained pain after injury
December 13, 2018 - Children with high levels of callous traits show widespread differences in brain structure
December 13, 2018 - Long-term Benefit of Steroid Injections for Knee Osteoarthritis Challenged
December 13, 2018 - Adding new channels to the brain remote control
December 13, 2018 - In the Spotlight: A different side of neuroscience
December 13, 2018 - Medical Marvels: Using immunotherapy for melanoma that spread to the brain
December 13, 2018 - Puzzles do not keep dementia away finds study
December 13, 2018 - New mouse model shows potential for rapid identification of promising muscular dystrophy therapies
December 13, 2018 - Study reveals urban and rural differences in prenatal exposure to essential and toxic elements
December 13, 2018 - New collaborative partnership in quest of novel antibiotics
December 13, 2018 - Single tau molecule holds clues to help diagnose neurodegeneration in its earliest stages
December 13, 2018 - AHA Scientific Statement: Low Risk of Side Effects for Statins
December 13, 2018 - What Is Acute Flaccid Myelitis?
December 13, 2018 - How bereaved people control their thoughts without knowing it
December 13, 2018 - Health care democratization underway, according to 2nd annual Stanford Medicine Health Trends Report | News Center
December 13, 2018 - Going Beyond a Single Color
December 13, 2018 - London-based startup launches ‘thedrug.store’ aiming to clean up CBD industry
December 13, 2018 - Loss of tight junction barrier protein results in gastric cancer development
December 13, 2018 - Novel way to efficiently deliver anti-parasitic medicines
December 13, 2018 - RKI publishes new data on disease prevention and utilization of medical services
December 13, 2018 - High-tech, flexible patches sewn into clothes could help to stay warm
December 13, 2018 - The CCA releases three reports on requests for medical assistance in dying
December 13, 2018 - Restoring Hair Growth on Scarred Skin? Mouse Study Could Show the Way
December 13, 2018 - Probiotic use may reduce antibiotic prescriptions, researchers say
December 13, 2018 - Drug repositioning strategy identifies potential new treatments for epilepsy
December 13, 2018 - Chronic rhinitis associated with hospital readmissions for asthma and COPD patients
December 13, 2018 - Food poisoning discovery could save lives
December 13, 2018 - Cloned antibodies show potential to treat, diagnose life-threatening fungal infections
December 13, 2018 - Exercise may reduce colorectal cancer risk after weight loss
December 13, 2018 - Russian scientists create hardware-information system for brain disorders treatment
December 13, 2018 - Moderate alcohol consumption linked with lower risk of hospitalization
December 13, 2018 - Nurturing Healthy Neighborhoods | NIH News in Health
December 13, 2018 - Rise in meth and opioid use during pregnancy
December 13, 2018 - Researchers gain new insights into pediatric tumors
December 13, 2018 - FSU study finds racial disparity among adolescents receiving flu vaccine
December 13, 2018 - Study investigates attitudes toward implementation of ‘sex as a biological variable’ policy
December 13, 2018 - Drug cocktail induces cancer cell death by switching off energy supply
Cooling glove helps athletes and patients

Cooling glove helps athletes and patients

image_pdfDownload PDFimage_print
Senior research scientist Dennis Grahn meets with student research assistant Riasoya Jodah, a Women’s Rugby team member. Jodah has been working with Heller and Grahn to test the effects of the cooling glove on strength conditioning training. Credit: L.A. Cicero

A cooling device that has been improving strength and endurance in mostly male athletes for 15 years is finding new uses in helping people with multiple sclerosis live normal lives, preventing overheating in Ebola workers and cooling working dogs. In a recent trial in women, it helped frosh participants perform hundreds of pushups in an hour.

The idea itself isn’t new. The mitten-like device is designed and built to draw heat out of the body’s core and has been shown to radically improve both strength and endurance. Now, Craig Heller, a professor of biology; Dennis Grahn, a senior research scientist in biology; and their lab are testing it in a variety of new settings and verifying that it is as effective in women as in men.

“One of the suggestions that always comes up is that it works on males because of the hormonal background,” Heller said, and that it might not have the same dramatic effects on women – but that suggestion appears to be wrong.

“We’ve actually had some freshmen women doing over 800 pushups” in less than an hour, Heller said.

The basic idea, Heller said, is to run cool water through a sort of mitten covering a person’s palms. The non-hairy skin of palms, soles and the face contain special blood vessels that can carry a high volume of blood to those surfaces to facilitate heat loss to the environment, Heller said.

Warming patients

Heller, who is also a member of Stanford Bio-X, said none of that would have happened had it not been for a physician friend challenging his lab with the opposite problem – rewarming patients after surgery, which can reduce body temperatures sometimes by as much as 1 or 2 degrees Celsius. Twenty years ago, no one had a particularly good, fast way to restore that lost heat.

Heller and Grahn, who worked on mammalian temperature regulation, came up with a simple device to rewarm patients: an airtight sleeve fitted over the arm, a water perfused pad in the sleeve, and a vacuum pump to create a negative pressure in the sleeve to increase blood flow in the arm. The idea was to draw blood out of a person’s core – the critical organs that actually need warming – into the arm where the blood was warmed before flowing back into the core.

The idea worked, and soon the researchers understood why. “We discovered it had nothing to do with the arm. It was only the hand,” Heller says, where special blood vessels bypass high-resistance capillaries and directly deliver blood into low-resistance veins that are arranged in a large network.

“These special blood vessels are found in the non-hairy skin. We are mammals. Most mammals have fur, so they can only dissipate heat from their non-hairy skin. We don’t have fur, but we have inherited the same specialized heat loss blood vessels,” Heller said. In essence, the non-hairy skin of the palms of our hands, soles of our feet and the upper part of our face (where we blush) are natural radiators that cool the body.

Cooling gloves heat up

Heller and team parlayed that discovery into a cooling glove that they found could keep a person’s muscles and core from overheating and, in the process, improve athletic performance. Early tests with a gym-frequenting research assistant, Vinh Cao, showed that cooling his palms in between sets increased the total number of pullups he could do in a single workout from 10 sets with 30-minute rests between to more than 600.

Subsequent tests showed the cooling method also improved endurance during cardiovascular exercise and had lasting effects on strength and endurance, but all of that early testing was in men. The cooling glove is used by Stanford athletic teams and many professional athletic teams in the United States and elsewhere in the world.

Now the group is verifying their assumption that the glove will work as well in women athletes as men by testing it in women Stanford students and staff. The participants are doing a variety of exercises and testing to see if the cooling device improves performance and recovery. So far the answer appears to be yes.

They are also exploring the device’s use in cooling overheated athletes and branching out beyond athletics to a backpack-sized system for working dogs – a project funded by the U.S. Navy – and for medical uses.

“We first got motivated to do that by some communications from Ebola workers in Sierra Leone,” Heller said, where hot temperatures and protective equipment combined to make overheating a serious problem.

Wearable cooling devices could also help patients with multiple sclerosis, who suffer symptom exacerbation when experiencing high environmental or body temperatures. Some MS patients using the current version of the technology have been able to leave their air-conditioned homes in summer and return to playing golf and engaging in other activities in spite of warm weather.


Explore further:
Stanford researchers’ cooling glove ‘better than steroids’

Provided by:
Stanford University

Tagged with:

About author

Related Articles