Breaking News
March 22, 2018 - Researchers explain link between 2 key Alzheimer’s proteins
March 22, 2018 - Patients on replacement therapy with thyroid hormone may have more comorbidities
March 22, 2018 - Higher online patient ratings linked to urologists who saw fewer Medicare patients
March 22, 2018 - FDA Approves Ilumya (tildrakizumab-asmn) for the Treatment of Moderate-to-Severe Plaque Psoriasis
March 22, 2018 - Beer Raises Heart Rate; KardiaBand Hyperkalemia Test; CHD Clinics
March 22, 2018 - A retinal implant that is more effective against blindness
March 22, 2018 - New system based on artificial intelligence provides reliable detection of breast cancer
March 22, 2018 - Research offers new understanding about cause of Parkinson’s disease
March 22, 2018 - HORIBA’s Microsemi CRP analyzer improves quality of care in emergency pediatric units, study shows
March 22, 2018 - Range of Vaginal Dryness Products Can Help Postmenopausal Women: Study
March 22, 2018 - Higher Dose Tx Deemed Safe in Pulmonary TB
March 22, 2018 - Discovery of new ALS gene points to cytoskeleton as potential target for drug development
March 22, 2018 - Diet soda associated with higher odds of diabetic retinopathy
March 22, 2018 - LSD reduces ‘sense of self’
March 22, 2018 - Vitamin D deficiency linked to metabolic syndrome in postmenopausal women
March 22, 2018 - Changes in the intestines may be responsible for reversal of diabetes after bariatric surgery
March 22, 2018 - iPads and Cancer; Clot Retrieval and Stroke: It’s PodMed Double T!
March 22, 2018 - Premature births linked to changes in mother’s bacteria
March 22, 2018 - Brain SPECT scans predict treatment outcomes in patients with depression
March 21, 2018 - Researchers succeed in integrating artificial organelles into cells of living organism
March 21, 2018 - Researchers discover ‘missing mutation’ in severe infant epilepsy
March 21, 2018 - Researchers develop statistics-based computational scheme to zoom in on brain function
March 21, 2018 - Verge joins Genomics England’s Discovery Forum industry partnership
March 21, 2018 - Trovagene Announces First Patient Successfully Completes Cycle 1 of Treatment with PCM-075 in Combination with Low Dose Cytarabine (LDAC) in AML Trial
March 21, 2018 - Congenital Cardiac Cath Tx Often Strays from Guidelines
March 21, 2018 - Marked increase in cardiovascular risk factors in women after preeclampsia
March 21, 2018 - New app may help predict, track manic and depressive episodes in bipolar patients
March 21, 2018 - Discovery of genes could lead to development of novel therapies for EBV-related cancers
March 21, 2018 - High-fat, high-cholesterol diet depletes ranks of artery-protecting immune cells
March 21, 2018 - Research misconduct allegations shadow likely CDC appointee
March 21, 2018 - Most Breast Ca Patients Fail to Get Genetic Counseling
March 21, 2018 - Lopsided ear function can lead to lopsided brain development
March 21, 2018 - Acupuncture helps manage menopausal symptoms, review finds
March 21, 2018 - Motor skill training may contribute to reading skills in obese children
March 21, 2018 - Poor dental health may be related to increased diabetes risk
March 21, 2018 - Chronic opioid users at increased risk of complications after spinal fusion surgery
March 21, 2018 - Study uncovers potential therapeutic target against large family of parasites
March 21, 2018 - NSAID use linked to increased risk of atrial fibrillation
March 21, 2018 - Scientists develop brain “stethoscope” that can detect silent seizures
March 21, 2018 - New method predicts effects of global warming on disease
March 21, 2018 - Insurance Company Hurdles Burden Doctors, May Harm Patients
March 21, 2018 - Renal Transplant from HCV-Positive Donors Feasible
March 21, 2018 - Myelodysplastic syndrome: MedlinePlus Medical Encyclopedia
March 21, 2018 - Research reveals brain mechanism involved in language learning
March 21, 2018 - Many parents still hesitate to try early peanut introduction, survey finds
March 21, 2018 - Audiologist urges tinnitus sufferers facing ‘revolving door healthcare’ to seek support
March 21, 2018 - Study reveals impact of prostate cancer on wives and partners of sufferers
March 21, 2018 - ‘Almost a Miracle Drug’: What We Heard This Week
March 21, 2018 - Study shows NIH spent >$100 billion on basic science for new medicines
March 21, 2018 - Columbia researchers identify nerve cells that drive fruit fly’s escape behavior
March 21, 2018 - Sartorius Stedim Biotech selected by ABL Europe to supply single-use process technologies
March 21, 2018 - Increase in coffee consumption may help battle against colon cancer
March 21, 2018 - Hydrogel may accelerate healing of diabetic ulcers
March 21, 2018 - Dermira’s Two Phase 3 Trials Evaluating Olumacostat Glasaretil in Patients with Acne Vulgaris Did Not Meet Co-Primary Endpoints
March 21, 2018 - DePuy Synthes introduces ACTIS Total Hip System for improving initial implant stability
March 21, 2018 - ‘Oh, It Was Nothing’
March 21, 2018 - Herbal drug kratom linked to salmonella illnesses, CDC says
March 21, 2018 - New optical point-of-care device could enhance screening for thyroid nodules
March 21, 2018 - FDA Expands Approval of Adcetris (brentuximab vedotin) for First-Line Treatment of Stage III or IV Classical Hodgkin Lymphoma in Combination with Chemotherapy
March 21, 2018 - Eosinophilic Esophagitis: Late Manifestation of Allergic March
March 21, 2018 - Signaling pathway involving the Golgi apparatus identified in cells with Huntington’s disease
March 21, 2018 - Quintupling inhaled steroid doses may not benefit children with asthma
March 21, 2018 - Study shows clear connection between cardiovascular fitness in middle age and dementia risk
March 21, 2018 - Premature babies have higher risks of health complications in Bangladesh
March 21, 2018 - Child’s temperament and parenting influence weight gain in babies
March 21, 2018 - Researchers find the heart to be capable of arrhythmia termination after local gene therapy
March 21, 2018 - Inhealthcare to provide digital infrastructure for NHS to help protect people from falls
March 21, 2018 - Flu Season Finally Slowing Down
March 21, 2018 - Mixed Results for Shorter DAPT in ACS Patients
March 21, 2018 - Scientists discover fish scale-derived collagen effective for healing wounds
March 21, 2018 - Genomics England announces new partnership to improve efficiency of next-generation sequencing analysis
March 21, 2018 - Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients
March 21, 2018 - Researchers identify new treatment targets for lung diseases using big data
March 21, 2018 - Kids see more women in science than five decades ago
March 21, 2018 - Research shows link between chronic fatigue syndrome and lower thyroid hormone levels
March 21, 2018 - Alzheimer’s disease on the rise
March 21, 2018 - Two Agents Equal as Pretreatment for Adrenal Tumor Surgery
March 21, 2018 - ‘Icebreaker’ protein opens genome for T cell development, researchers find
March 21, 2018 - Women in medicine shout #Metoo about sexual harassment at work
March 21, 2018 - Mother’s pre-pregnancy waist size may be linked to child’s autism risk
Big Strides Made in Diabetes Care

Big Strides Made in Diabetes Care

image_pdfDownload PDFimage_print

FRIDAY, Jan. 5, 2018 — This past year was a busy, productive one for diabetes research and care.

“2017 was a year of progress in our understanding of diabetes and its complications, the tools available to help people manage their diabetes, and attention to the economic and accessibility challenges faced by people with diabetes,” said Dr. William Cefalu, chief scientific and medical officer for the American Diabetes Association (ADA).

Strides were made in:

Artificial pancreas technology

Probably the biggest and most anticipated news of 2017 was the rollout of the so-called artificial pancreas. Created by Medtronic, the device combines an insulin pump, a continuous glucose monitor and a computer algorithm that measures blood sugar levels and then delivers insulin automatically when those levels rise. Insulin delivery is also temporarily suspended if blood sugar levels drop too low.

The device isn’t completely automated yet. People with diabetes still need to know how to count the carbohydrates in their food and enter that information into their insulin pump.

And the device still requires people with diabetes to check their blood sugar several times a day and enter that information into the machine — this is known as “calibrating.” The hope is that future versions of the device won’t require these steps.

Aaron Kowalski, chief mission officer for JDRF (formerly the Juvenile Diabetes Research Foundation), said, “We’ve waited a long time to see these systems come to market, and while it’s not yet perfect, it has opened the door, and there’s definitely a benefit.”

He added that a number of other insulin pump manufacturers and independent companies are working on their own artificial pancreas systems. “Competition is really important and helps drive innovation. The next few years will hold promise,” Kowalski added.

Improving heart health

Heart disease is a significant concern for people with diabetes. New research suggested that long-term use of metformin could reduce the risk of heart disease in people with type 1 diabetes. Other medications have been linked to a reduced risk of heart disease in people with type 2 diabetes. These include Jardiance, Invokana and Victoza.

“Cardiovascular disease is the most deadly and expensive complication of diabetes, and a number of recent studies have shown that certain medications also have a strong protective effect against cardiovascular disease in people at high risk for it,” Cefalu said.

Competition in the continuous glucose monitor (CGM) market

The artificial pancreas wasn’t the only innovation in diabetes technology in 2017. Another continuous glucose monitoring device (CGM) was approved by the U.S. Food and Drug Administration (FDA). Made by Abbott and called the Libre, this device has been in use in Europe for several years.

The major difference in the Libre is that you have to request the blood sugar information. Other devices on the market — from Dexcom and Medtronic — send blood sugar information collected by a tiny sensor wire inserted under the skin to a receiver every five minutes or so.

The Libre also uses a tiny sensor wire inserted under the skin, but the person with diabetes has to request the information be sent to the receiver. In addition, the Libre also doesn’t require any fingerstick calibration as other devices on the market do.

“Some people find the constant information provided by continuous glucose monitors to be stressful. With the Libre, you ask when you want the information. It’s also a little bit flatter than other CGMs, and it comes in at a much lower price point,” Kowalski explained.

Improving blood sugar levels in pregnant women with type 1 diabetes

One of the most promising uses of CGM technology became evident with the publication of the results of an international study of women with type 1 diabetes who wore the devices during pregnancy. Women with type 1 diabetes have to manage their blood sugar levels very tightly during pregnancy, because high blood sugar levels are associated with birth defects and other pregnancy complications. But this also puts them at risk of developing dangerously low blood sugar levels.

Women using CGM spent more time in “target” range than women who didn’t. That means their blood sugar was neither too high nor too low for longer periods of time.

“This study helped show that mothers and babies do better when the mother [with type 1 diabetes] has a CGM,” Kowalski said. The study was published in The Lancet.

Insulin speed

Novo Nordisk received FDA approval for a new insulin called Fiasp. This insulin starts working in about 2.5 minutes. Currently, Novolog, another product from Novo Nordisk, takes approximately five to 10 minutes to start working.

That difference may not seem like much, but unless people with diabetes who are dependent on insulin inject at least five to 10 minutes before they eat, their blood sugar levels may spike too high after eating.

It’s not always possible or even safe to pre-inject insulin. For example, in a restaurant, you have no way of knowing when your food might arrive, and if you pre-inject and your food is late, you can have a dangerously low blood sugar level. The shorter time it takes Fiasp to work could help prevent spikes in blood sugar after eating, which ultimately leads to better diabetes control.

Awareness of costs and increased coverage

The cost of insulin has come under sharp scrutiny recently because the cost of some insulin has tripled in about a decade. Sen. Bernie Sanders (I-Vt.) first brought the issue up during the 2016 presidential campaign. The ADA started a campaign called “Make Insulin Affordable” and is working with members of Congress to bring more attention to the issue.

This was also the first year that people on Medicare with diabetes could get coverage for all CGMs. Initially, Medicare only offered coverage for the Dexcom CGM, but on Jan. 4 the agency announced that it would also cover the Libre CGM.

More information

Learn more about diabetes from the U.S. National Institute of Diabetes and Digestive and Kidney Diseases.

© 2018 HealthDay. All rights reserved.

Posted: January 2018

Tagged with:

About author

Related Articles