Breaking News
May 21, 2018 - FDA Approves Aimovig (erenumab-aooe) as a Preventive Treatment for Migraine
May 21, 2018 - Infant death study reveals dangerous sleep practices among babysitters, relatives, others
May 21, 2018 - Intermittent fasting may increase diabetes risk, shows study
May 21, 2018 - New study shows declines in prostate cancer screening, diagnoses and treatment
May 21, 2018 - Fasting diets could raise risk of diabetes say experts
May 21, 2018 - FDA Alert: 7K and Poseidon 4500 by Shoreside Enterprises: Voluntary Recall
May 21, 2018 - Cell phones at summer camp: Research explores the effects
May 21, 2018 - Birth rate decline driven by waiting longer to have children, cost of infertility treatment
May 21, 2018 - In-hospital opioid prescribing may increase post-discharge opioid use, shows study
May 21, 2018 - ABPI expert urges to find new ‘blockbuster treatments’ for brain tumors
May 21, 2018 - Disruption of Circadian Rhythm Negatively Impacts Mental Health
May 21, 2018 - Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder
May 21, 2018 - World first use of cognitive training reduces gait freezing in Parkinson’s patients
May 21, 2018 - NIH stops alcohol study that was looking at purported health benefits of drinking
May 21, 2018 - Higher belly fat levels linked to greater risk of vitamin D deficiency
May 21, 2018 - Scientists collate evidence for mismatch between past evolutionary adaptation and modern lives
May 21, 2018 - New case report reveals negative clinical impact of using biotin supplement
May 21, 2018 - Researchers discover new disease mechanism in chronic tobacco smokers
May 21, 2018 - Breast Cancer Patients May Shorten Herceptin Regimen: Study
May 21, 2018 - Bias keeps women with higher body weights away from the doctor: study
May 21, 2018 - Researchers identify protein essential for eye lens development and clear vision
May 21, 2018 - Frontal cortical lesions moderate response to prism adaptation treatment after stroke
May 21, 2018 - Ultrasound guidelines can reliably differentiate between pediatric thyroid nodules that require biopsy
May 21, 2018 - Weight loss is an important predictor of cancer
May 21, 2018 - Ozone exposure at birth linked to increased risk of developing asthma in childhood
May 21, 2018 - CT scan still effective to determine thrombectomy treatment in stroke, study shows
May 21, 2018 - Clot busting drug combo reduces risk of major strokes in high risk patients
May 21, 2018 - New airway transplantation technique shows promising results in lung cancer patients
May 21, 2018 - Biomarker blood test does not appear to curb antibiotic overuse, shows new study
May 21, 2018 - Lilly’s Galcanezumab Meets Primary Endpoint in Phase 3 Study Evaluating Galcanezumab for the Prevention of Episodic Cluster Headache
May 21, 2018 - Grief symptoms similar in donor vs non-donor decision families
May 21, 2018 - Congo to start vaccinating populations against Ebola today to combat outbreak
May 21, 2018 - Researchers use MR spectroscopy to investigate mechanisms behind targeted treatment for gliomas
May 21, 2018 - Study reveals why older workers have higher stress levels than younger colleagues
May 21, 2018 - Health Tip: Taming a Pollen Allergy
May 21, 2018 - Inducing labor at 39 weeks reduces risks of C-section and other complications
May 20, 2018 - Developmental psychotherapy aims at helping antisocial adolescents become responsible adults
May 20, 2018 - People with OCD process emotions differently than their unaffected siblings
May 20, 2018 - Interfering with enzyme’s movement may be new approach for developing of anti-cancer drugs
May 20, 2018 - Prestroke and poststroke oral anticoagulation therapy in AF patients
May 20, 2018 - Why drug users prefer heroin at home, but cocaine while out
May 20, 2018 - Gene therapy that reverses blindness in dogs could also help treat humans
May 20, 2018 - Opioid-Related Payments Linked to Increase in Opioid Rx
May 20, 2018 - Phone apps push people to take their pills
May 20, 2018 - Backbreaking Work May Shorten Men’s Lives
May 20, 2018 - Harsher drug laws won’t stop violence, argues former police chief
May 20, 2018 - Cognitive decline in dementia is not reduced by exercise
May 20, 2018 - Detecting breast cancer with non-invasive ‘disease screening pill’
May 20, 2018 - Simple treatment may minimize hearing loss triggered by loud noises
May 20, 2018 - Alignment of mother and offspring body clock could prevent diseases such as heart disease and obesity
May 20, 2018 - New commercial data warehouse for life sciences
May 20, 2018 - Practice Intervention Targeting IV Opioids May Cut Exposure
May 20, 2018 - New study provides insight into blood signatures of inflammation
May 20, 2018 - Scientists make breakthrough discovery about vitamin B12
May 20, 2018 - What Causes Cancer? Misconceptions Abound
May 20, 2018 - Proper burial of dead cells limits inflammation
May 20, 2018 - Study offers novel solution to suppress metastatic spread of deadly breast cancer
May 20, 2018 - Perspectives of patients and caregivers on care transitions
May 20, 2018 - Guidelines for weight gain in pregnancy should be changed for underweight and very obese women
May 20, 2018 - Researchers transplant retinal sheets derived from human embryonic stem cells in retinal degeneration mouse models
May 20, 2018 - U.S. military personnel at greater risk for skin cancer than general population
May 20, 2018 - Your immune system holds the line against repeat invaders, thanks to this molecule
May 20, 2018 - Between death and deportation
May 20, 2018 - Developing a High Throughput Mass Spectrometry Platform for Drug Discovery
May 19, 2018 - New project aims to increase awareness among hospital clinicians of non-beneficial treatment at end-of-life
May 19, 2018 - Automated bone scan index offers accurate, speedy prognostic information about prostate cancer
May 19, 2018 - Rutgers Cancer Institute nurses research various topics to enhance patient experience
May 19, 2018 - Computer models provide valuable insight to structure and function of Ebola, Zika viruses
May 19, 2018 - Study exposes key tactic used by deadly fungus
May 19, 2018 - Bacterial signals are crucial to development of pre-leukemic myeloproliferation, study shows
May 19, 2018 - Global experts identify key issues in supporting children with brain injuries transition back to school
May 19, 2018 - Social connections may protect black men who have sex with men from acquiring HIV
May 19, 2018 - Study IDs Factors Linked to Quality of Life With Dementia
May 19, 2018 - Potassium — Consumer
May 19, 2018 - HIV-1 viruses transmitted at birth are resistant to antibodies in mother’s blood
May 19, 2018 - Some water pitchers are much better at removing toxins, shows research
May 19, 2018 - Scientists discover how unusually long strands of RNA help colon cancer cells avoid death
May 19, 2018 - International study finds viable treatment option for people with mild asthma
May 19, 2018 - Mayo discovery could enable development of personalized ovarian, brain cancer treatments
May 19, 2018 - ‘Superbug’ Surfaces at Poultry Farm in China
Egg-preserving hysterectomy raises heart risks later: study

Egg-preserving hysterectomy raises heart risks later: study

image_pdfDownload PDFimage_print

Women who undergo hysterectomy before age 35 may face significantly higher long-term heart risks, even if their ovaries are preserved, a study found Wednesday.

The research by experts at Mayo Clinic focused on more than 2,000 US women who had their uterus removed but left their ovaries intact—widely considered the most desirable option if possible because it prevents a woman from entering early menopause.

Compared to women in the same area of Minnesota who did not have hysterectomies, the study found those who did faced a greater risk of obesity, clogged arteries, high blood pressure and high cholesterol in the 20-plus years after surgery.

The elevated risks ranged from 13 percent more for high blood pressure to 33 percent more for coronary artery disease.

For women under age 35, the risks were particularly acute—a 4.6-fold increased risk of congestive heart failure and a 2.5-fold greater risk of coronary artery disease, when the arteries become hard and narrow, blocking blood flow.

“This is the best data to date that shows women undergoing hysterectomy have a risk of long-term disease—even when both ovaries are conserved,” said lead author Shannon Laughlin-Tommaso, an obstetrician-gynecologist at Mayo Clinic.

“Hysterectomy is the second most common gynecologic surgery, and most are done for benign reasons, because most physicians believe that this surgery has minimal long-term risks,” she added.

‘Consider alternatives’

Some 400,000 operations to remove the uterus, or womb, are performed each year in the United States.

Most are not due to life-threatening conditions like cancer, but rather because of painful fibroids, menstrual disorders or uterine prolapse, when the uterus begins to sag into the vagina, according to the study.

In cases of cancer or high genetic risks, doctors may remove the uterus, fallopian tubes and ovaries. In other cases, just the uterus is taken out, rendering a woman unable to become pregnant but preserving her hormonal function through the ovaries, thereby postponing menopause.

This option became more popular after research showed that removing the ovaries along with the uterus can raise the risk of early death and chronic disease.

But experts say the effects of ovary-preserving hysterectomies have not been well studied until now.

“While women are increasingly aware that removing their ovaries poses health risks, this study suggests hysterectomy alone has risks, especially for women who undergo hysterectomy prior to age 35,” said Laughlin-Tommaso.

“With the results of this study, we encourage people to consider nonsurgical alternative therapies for fibroids, endometriosis and prolapse, which are leading causes of hysterectomy.”

‘Fascinating’ research

According to obstetrician-gynecologist Jill Rabin, who was not involved in the study, the research is “well-powered” and “fascinating.”

While the biological reasons for the health risks are still being studied, researchers suggested that the uterus may play a role in communicating with the hormone-producing ovaries.

Therefore, removing the womb may cut blood flow and change hormonal stimulation to the ovaries, leading to negative effects on the entire body.

“It makes perfect sense if you think about it. It’s all connected. Once you disconnect it, it is like cutting a telephone line in a way. You are stopping the communication,” said Rabin, who is co-chief of the division of ambulatory care and women’s health programs at Northwell Health in New York.

Hysterectomy can also be a life-saving operation, depending on the reason, so women who are considering it should consult closely with their doctors, she added.

“It should be decided with your doctor, spelling out the risks and benefits, so the patient really understands.”

Since the study was observational in nature, it stops short of proving cause-and-effect, but raises interesting questions for further research, according to Mitchell Kramer, chairman of the department of obstetrics and gynecology at Huntington Hospital in New York.

In the meantime, any women thinking about the surgery “should consider alternatives to hysterectomy,” including treatment with medicines or less invasive procedures, he told AFP in an email.

The study was published in the journal Menopause.


Explore further:
Hysterectomy at younger age tied to heart disease risks

Journal reference:
Menopause

Tagged with:

About author

Related Articles