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Search of: Recruiting, Not yet recruiting, Available Studies | “Metabolic Syndrome” – List Results

Search of: Recruiting, Not yet recruiting, Available Studies | “Metabolic Syndrome” – List Results

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1 NCT03293264 Recruiting Exercise Training on Metabolic Syndrome Severity in Employees
  • Behavioral: Exercise training group
Interventional
  • Hannover Medical School
  • Volkswagen AG
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Investigator)
  • Primary Purpose: Health Services Research
  • Metabolic Syndrome (MetS) -Z-score
  • Work-Ability-Index (WAI)
  • Short Form 36 (SF36)
  • (and 5 more…)
300 All 18 Years and older   (Adult, Senior) NCT03293264 RebVW October 17, 2017 October 26, 2019 May 26, 2020 September 26, 2017 January 22, 2018
  • HannoverMS
    Hannover, Lower Saxony, Germany
2 NCT03107741 Recruiting Effectiveness of Tai Chi Training on Metabolic Syndrome
  • Other: Generic Fitness
  • Other: Tai Chi
Interventional
  • Angus Yu
  • The Hong Kong Polytechnic University
Other
  • Allocation: Randomized
  • Intervention Model: Factorial Assignment
  • Masking: Single (Investigator)
  • Primary Purpose: Treatment
  • Waist circumference (Baseline Assessment)
  • Waist circumference (Post-Intervention Assessment)
  • Waist circumference (Follow-up Assessment)
  • (and 12 more…)
390 All 50 Years and older   (Adult, Senior) NCT03107741 Tai Chi and Metabolic Syndrome October 2015 December 2017 June 2018 April 11, 2017 April 11, 2017
  • The Hong Kong Polytechnic University
    Hong Kong, China
  • The Hong Kong Polytechnic University
    Hong Kong, China
3 NCT02122666 Recruiting Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome Observational
  • Washington University School of Medicine
Other
  • Observational Model: Case Control
  • Time Perspective: Prospective
  • Sarcoplasmic Reticulum Composition
  • Insulin Sensitivity
  • Lean and Fat Body Mass
100 All 18 Years to 65 Years   (Adult) NCT02122666 201311988 COMP-SR March 2014 December 2017 December 2017 April 24, 2014 November 2, 2016
  • Washington University School of Medicine
    St. Louis, Missouri, United States
4 NCT01417247 Recruiting Renal Sympathetic Modification in Patients With Metabolic Syndrome
  • Procedure: renal sympathetic modification
Interventional
  • The Second Affiliated Hospital of Chongqing Medical University
  • Jiangsu Provincial People’s Hospital
  • Chongqing Medical University
Other
  • Allocation: Non-Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • composite cardiovascular events (myocardial infarction, heart failure, sudden death, cardiogenic death)
  • effect of glucose and lipid metabolism, and blood pressure variability
200 All 18 Years to 75 Years   (Adult, Senior) NCT01417247 SWAN-MS August 2011 June 2019 June 2020 August 16, 2011 July 17, 2017
  • 2ndChongqingMU
    Chongqing, Chongqing, China
5 NCT03355469 Recruiting Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome
  • Combination Product: LoEx+Metformin
  • Combination Product: HiEx+Metformin
  • Combination Product: LoEx+Placebo
  • Combination Product: HiEx+Placebo
Interventional Phase 4
  • University of Virginia
  • National Heart, Lung, and Blood Institute (NHLBI)
Other / NIH
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Prevention
  • Change in Flow Mediated Dilation of brachial artery
  • Change in Metabolic Insulin Sensitivity by the Euglycemic Clamp
  • Change in Post Ischemic Flow Velocity in brachial artery
  • (and 4 more…)
80 All 40 Years to 70 Years   (Adult, Senior) NCT03355469 19364
1R01HL130296-01A1 August 7, 2017 June 30, 2021 January 31, 2022 November 28, 2017 November 28, 2017
  • University of Virginia
    Charlottesville, Virginia, United States
6 NCT03214068 Not yet recruiting Evaluation of the Pattern of Thyroid Dysfunctions in Patients With Metabolic Syndrome Observational Other
  • Observational Model: Case-Control
  • Time Perspective: Other
  • Thyroid stimulating hormone
  • Lipid profile
200 All 20 Years to 70 Years   (Adult, Senior) NCT03214068 17100051 July 2017 June 2019 December 2019 July 11, 2017 July 11, 2017
7 NCT03058016 Not yet recruiting Personalized Nutrition Prediction for Metabolic Syndrome Patients, an Open Single-center Study
  • Other: Personalized recommendations for diet
Interventional Industry
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Prevention
  • To determine number of participants with reduced BMI
  • To determine number of participants with reduced hA1C
  • To determine number of participants with reduced cholesterol
  • (and 2 more…)
500 All 18 Years to 65 Years   (Adult) NCT03058016 98-16 April 1, 2017 April 1, 2022 April 1, 2022 February 20, 2017 February 20, 2017
8 NCT03338868 Recruiting Serum Concentrations, Physical and Psychological Well-being in Metabolic Syndrome
  • Other: Body composition
  • Other: Physical activity level
  • Other: Musculoskeletal pain intensity
  • (and 3 more…)
Observational
  • Ataturk Training and Research Hospital
Other
  • Observational Model: Case-Control
  • Time Perspective: Prospective
  • Blood tests
  • Body composition
  • Physical activity level
  • (and 3 more…)
100 All 20 Years to 70 Years   (Adult, Senior) NCT03338868 2015-13/32 August 1, 2015 November 30, 2017 December 30, 2017 November 9, 2017 November 17, 2017
  • Ataturk Training and Research Hospital
    Ankara, Cankaya, Turkey
  • Ataturk Training and Research Hospital
    Ankara, Cankaya, Turkey
9 NCT02746887 Recruiting Risk Factors Related to Metabolic Syndrome in School-aged Children Who Were Born Preterm
  • Other: Preterm/term cohort
Observational
  • Seoul National University Hospital
Other
  • Observational Model: Case Control
  • Time Perspective: Prospective
  • number of participants with abnormal laboratory values and/or abnormal physical status
  • The number of participants with catch-up growth failure
  • The number of participants with hypertension
120 All 8 Years to 8 Years   (Child) NCT02746887 1509-030-702 December 2015 November 2016 April 21, 2016 April 21, 2016
  • Seung Han Shin
    Seoul, Korea, Republic of
10 NCT02960711 Recruiting Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome
  • Drug: Metformin Hydrochloride 850 MG Oral Tablet [Glucophage]
  • Drug: Ludipress, mg stereate, micronized hydrated silica, talcum
Interventional Phase 3
  • Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Other
  • Allocation: Randomized
  • Intervention Model: Factorial Assignment
  • Masking: Double (Participant, Investigator)
  • Primary Purpose: Prevention
  • Total incidence of age related chronic diseases
  • Effect of the intervention on total mortality and on the incidence of specific chronic diseases.
2000 All 55 Years to 74 Years   (Adult, Senior) NCT02960711 INT 85-13 MeMeMe February 2014 July 2018 July 2018 November 10, 2016 November 10, 2016
  • Fondazione IRCCS Istituto Nazionale Tumori
    Milan, Italy
11 NCT02940366 Recruiting Effect of High-dose Pitavastatin on Glucose Control in Patients With Metabolic Syndrome
  • Drug: Pitavastatin 4 mg orally daily
  • Drug: Atorvastatin 20 mg orally daily
Interventional Phase 4
  • Seoul National University Hospital
  • JW Pharmaceutical
Other / Industry
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • Absolute change in HbA1c level
500 All 21 Years and older   (Adult, Senior) NCT02940366 1406-027-584 December 1, 2016 November 30, 2019 November 30, 2019 October 20, 2016 February 9, 2017
  • Seoul National University Hospital
    Seoul, Korea, Republic of
12 NCT02958579 Recruiting a Population Based Study on Metabolic Syndrome Complications, and Mortality
  • Other: No intervention will be done. Participants are on standard care and the treatments will be recorded because of observational nature of this study.
Observational
  • Tehran University of Medical Sciences
Other
  • Observational Model: Cohort
  • Time Perspective: Prospective
  • incidence of CVD
  • incidence of microvascular complications of T2D (diabetic retinopathy, diabetic neuropathy, diabetic kidney disease), and diabetic foot
  • incidence of non-alcoholic fatty liver disease (NAFLD)
  • (and 3 more…)
10000 All 40 Years to 70 Years   (Adult, Senior) NCT02958579 95-03-191-33053
957275 MetSCoM January 2005 January 2017 January 2020 November 8, 2016 November 8, 2016
  • Tehran University of Medical Sciences
    Tehran, Iran, Islamic Republic of
13 NCT02969720 Not yet recruiting Therapeutic Efficacy of Phytosterols on Metabolic Syndrome
  • Dietary Supplement: Phytosterols
  • Dietary Supplement: Titanium Dioxide
Interventional Phase 3
  • Universidad Los Andes, Chile
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Double (Participant, Care Provider)
  • Primary Purpose: Treatment
  • Difference of proportion between study groups in the proportion of metabolic syndrome from baseline and the last visit (180 days).
200 All 18 Years to 65 Years   (Adult) NCT02969720 FESIME-016 FESIME March 2017 October 2017 December 2017 November 21, 2016 November 21, 2016
14 NCT02531334 Recruiting Effects of TA-65, a Telomerase Activator on Metabolic Syndrome
  • Dietary Supplement: TA-65
Interventional
  • University of Connecticut
Other
  • Allocation: Randomized
  • Intervention Model: Crossover Assignment
  • Masking: Double (Participant, Investigator)
  • Primary Purpose: Treatment
  • Plasma insulin
  • Plasma HDL cholesterol
40 All 32 Years to 70 Years   (Adult, Senior) NCT02531334 H14-278 August 2015 June 2017 December 2017 August 24, 2015 January 6, 2017
  • University of Connecticut
    Storrs, Connecticut, United States
15 NCT02783703 Recruiting Evaluation of MCT in a Mixed Racial Population of Patients With Metabolic Syndrome: a Feasibility Study
  • Dietary Supplement: Medium chain triglycerides (MCT)
Interventional
  • Boston Medical Center
  • Boston University
Other
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Other
  • Change from baseline in insulin sensitivity to 6 weeks as measured by intravenous glucose tolerance test
  • Change from baseline to 6 weeks in resting energy expenditure (kilocalories)
  • Change from baseline to 6 weeks in body composition (% fat, muscle and bone)
  • (and 2 more…)
20 All 18 Years to 65 Years   (Adult) NCT02783703 H-35267 April 28, 2017 June 2018 June 2018 May 26, 2016 January 4, 2018
  • Boston Medical Center
    Boston, Massachusetts, United States
16 NCT02606812 Not yet recruiting Effect of Food Consumption on microRNA Related to Metabolic Syndrome
  • Dietary Supplement: Traditional-food
Interventional
  • Universidad Juárez Autónoma de Tabasco
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Investigator)
  • Changes on biochemical parameters and selected miRNA
50 All 20 Years to 22 Years   (Adult) NCT02606812 UniversidadJAT EFCMRNAMS March 2017 April 2017 April 2018 November 17, 2015 October 26, 2016
17 NCT03300271 Not yet recruiting Effects of a Supportive Mobile Application for Life Style Modification on Blood Pressure and Insulin Resistance Improvement in People With Metabolic Syndrome
  • Other: Mobile application for self monitoring
  • Other: Education
  • Other: Mobile application for personal coaching
Interventional Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Double (Investigator, Outcomes Assessor)
  • Primary Purpose: Prevention
  • Change in systolic/diastolic blood pressures
  • Change in the eligibility criteria for metabolic syndrome
150 All 30 Years to 59 Years   (Adult) NCT03300271 4-2017-0666 October 2017 June 2018 June 2018 October 3, 2017 October 3, 2017
  • Yonsei University College of Medicine
    Seoul, Korea, Republic of
18 NCT03241394 Recruiting The Monocyte Subsets in Obese Patients With and Without Metabolic Syndrome
  • Obesity
  • Metabolic Syndrome
Observational
  • University Hospital, Ioannina
Other
  • Observational Model: Other
  • Time Perspective: Cross-Sectional
100 All 18 Years to 70 Years   (Adult, Senior) NCT03241394 802 July 25, 2017 September 15, 2017 September 15, 2017 August 7, 2017 August 7, 2017
  • University Hospital of Ioannina
    Ioánnina, Greece
19 NCT02633891 Recruiting Metabolic Syndrome and Fall Risk
  • Metabolic Syndrome
  • Autonomic Neuropathy
  • Behavioral: Balance exercise
  • Behavioral: Standard care
Interventional
  • VA Office of Research and Development
  • University of Maryland
U.S. Fed / Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Outcomes Assessor)
  • Primary Purpose: Treatment
  • Four Square Step Test (FSST)
  • Dynamic Gait Index (DGI)
55 All 50 Years to 70 Years   (Adult, Senior) NCT02633891 F1651-W
1IK2RX001651-01A2 January 2, 2017 July 1, 2020 December 31, 2020 December 17, 2015 August 29, 2017
  • Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
    Baltimore, Maryland, United States
20 NCT02651454 Recruiting A Pilot Study Exploring the Efficacy and Safety of Herbal Medicine on Korean Obese Women With Metabolic Syndrome Risk Factors – Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial –
  • Metabolic Syndrome
  • Obesity
  • Drug: Daesiho-tang
  • Drug: Jowiseungcheung-tang
  • Drug: Placebo
Interventional Phase 4
  • Gachon University Gil Oriental Medical Hospital
  • Sangji University Oriental Medical Hospital, Korea
  • DongGuk University
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment
  • Changes from baseline in body weight
  • Changes from baseline in body fat percentage
  • Changes from baseline in fat mass
  • (and 9 more…)
120 Female 18 Years to 65 Years   (Adult) NCT02651454 ISEE_2015_OBESITY December 2015 December 2018 December 2019 January 11, 2016 January 8, 2018
  • Gachon University Gil Oriental Medical Hospital
    Incheon, Korea, Republic of
21 NCT02641925 Recruiting Omentectomy for Metabolic Syndrome in Gastric Cancer Patients
  • Metabolic Syndrome
  • Gastric Cancer
  • Procedure: Omentum preserving
  • Procedure: Total omentectomy
Interventional
  • Keimyung University Dongsan Medical Center
  • Chonnam National University Hospital
  • Dong-A University Hospital
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • HOMA-IR change
  • prevalence of metabolic syndrome
  • Complication
  • HOMA-IR change according to anastomosis type
60 All 20 Years to 80 Years   (Adult, Senior) NCT02641925 2015-07-010
KSWEET-02 August 2015 August 2019 August 2020 December 30, 2015 June 1, 2017
  • Chonnam National University Hwasun Hospital
    Hwasun, Jeollanam-do, Korea, Republic of
  • Dong-A University Hospital
    Busan, Korea, Republic of
  • Keimyung University Dongsan Medical Center
    Daegu, Korea, Republic of
22 NCT03266055 Not yet recruiting Effects of Blueberry on Gut Microbiota and Metabolic Syndrome
  • Gut Microbiota
  • Metabolic Syndrome
  • Dietary Supplement: 50 g of blueberry powder, taken daily for 8 weeks
  • Dietary Supplement: 50g of placebo blueberry powder, taken daily for 8 weeks
Interventional Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Participant)
  • Primary Purpose: Prevention
  • Changes in plasma insulin/glucose of overweight/obese men and women taking either blueberry powder or placebo blueberry powder
  • Changes in plasma lipids/lipoproteins of overweight/obese men and women taking either blueberry powder or placebo blueberry powder
  • Changes in gene expression in overweight/obese men and women taking either blueberry powder or placebo blueberry powder
  • (and 5 more…)
56 All 18 Years to 55 Years   (Adult) NCT03266055 BLEUET 2017-135 August 2017 December 2018 June 2019 August 29, 2017 August 29, 2017
23 NCT03292042 Recruiting Effectiveness of a Lifestyle Intervention, for People With SMI Who Meet Metabolic Syndrome Criteria
  • Behavioral: Physical health promotion program
Interventional
  • Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
  • University of Barcelona
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Care Provider)
  • Primary Purpose: Treatment
  • Decrease of at least 3 of the 5 criteria of metabolic syndrome
  • Metabolic syndrome prevalence
  • use of antipsychotic
  • (and 2 more…)
60 All 18 Years to 65 Years   (Adult) NCT03292042 109-17 September 1, 2017 August 31, 2018 May 1, 2019 September 25, 2017 September 26, 2017
  • university hospital Ramón y Cajal
    Madrid, Spain
24 NCT03087721 Recruiting High-intensity Interval, Low Volume Training in Metabolic Syndrome
  • Metabolic Syndrome
  • Insulin Resistance
  • Behavioral: HIIT-LV
  • Behavioral: CAE
Interventional
  • Universidad de Antioquia
  • Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS)
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Outcomes Assessor)
  • Primary Purpose: Treatment
  • Insulin sensitivity
  • Insulin resistance
  • Pancreatic β-cell function
  • (and 5 more…)
60 All 40 Years to 60 Years   (Adult) NCT03087721 54-2016 Intraining-MET March 1, 2017 September 29, 2018 December 31, 2018 March 22, 2017 March 22, 2017
  • IPS-Universitaria
    Medellin, Antioquia, Colombia
25 NCT03031821 Not yet recruiting Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome
  • Prostate Cancer
  • Metabolic Syndrome
  • Drug: Metformin
  • Drug: Placebo Oral Tablet
Interventional Phase 3
  • Canadian Urologic Oncology Group
  • Prostate Cancer Canada
  • British Columbia Cancer Agency
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Prevention
  • Proportion of patients who meet the diagnostic criteria for metabolic syndrome after 18 months of study treatment
  • Proportion of patients who meet the diagnostic criteria for metabolic syndrome after 9 months of study treatment
  • Proportion of patients who meet the diagnostic criteria for metabolic syndrome after 12 months of study treatment
  • (and 8 more…)
300 Male 18 Years and older   (Adult, Senior) NCT03031821 PRIME PRIME October 1, 2017 June 1, 2020 June 1, 2023 January 26, 2017 August 9, 2017
  • BC Cancer Agency – Vancouver Cancer Centre
    Vancouver, British Columbia, Canada
26 NCT02252406 Recruiting Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome
  • Stable Angina
  • Metabolic Syndrome
  • Drug: Ranolazine
  • Drug: Placebo
Interventional Phase 4 Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment
  • Improvement of angina
  • Change in Biomarkers in response to ranolazine.
40 Female 18 Years to 75 Years   (Adult, Senior) NCT02252406 WIRB20141202 IRMA September 2015 March 2018 July 2018 September 30, 2014 October 26, 2017
  • University of Florida
    Jacksonville, Florida, United States
27 NCT03296514 Recruiting Mindfulness Based Stress Reduction for Metabolic Syndrome Interventional Other
  • Allocation: Randomized
  • Intervention Model: Crossover Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Other
  • Self- reported physical health status
  • Perceived stress
  • Mindfulness Skills
40 All 60 Years to 90 Years   (Adult, Senior) NCT03296514 2000020175 MBSR July 1, 2017 July 1, 2018 July 1, 2018 September 28, 2017 September 28, 2017
  • Yale University
    New Haven, Connecticut, United States
28 NCT02918422 Recruiting Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption
  • Other: Nutritional and Dietary Manipulation
Interventional Other
  • Allocation: Randomized
  • Intervention Model: Crossover Assignment
  • Masking: None (Open Label)
  • Change in Plasma Fatty Acid Composition and Lipoprotein Analysis
  • Change in Body Composition as Assessed by DEXA and MRI
  • Change in Blood-based Inflammation Markers
  • Change in Blood Metabolite Profiles
30 All 21 Years to 65 Years   (Adult) NCT02918422 GRT00036921
60047084 September 2015 March 2018 March 2018 September 29, 2016 September 29, 2016
  • Physical Activity and Education Services – PAES
    Columbus, Ohio, United States
29 NCT03009279 Not yet recruiting Relationship of Metabolic Syndrome and Its Components With Thyroid Nodule(s)
  • Metabolic Syndrome
  • Thyroid Nodule
Observational
  • Lin Liao
  • Qianfoshan Hospital
Other
  • The laboratory examinations
  • Blood pressure of patients in each group
10000 All 15 Years to 90 Years   (Child, Adult, Senior) NCT03009279 qfsnfm-004 January 2017 November 2017 December 2017 January 4, 2017 January 9, 2017
30 NCT02968160 Recruiting A Clinical Trial of YMC017 in Hypertensive and Hypercholesterolemic Patients With Metabolic Syndrome
  • Drug: Telmisartan 40mg + Rosuvastatin 20mg
  • Drug: Telmisartan 80mg + Rosuvastatin 20mg
  • Drug: Telmisartan 40mg, 80 mg
  • Drug: Rosuvastatin 20mg
Interventional Phase 4
  • Yuhan Corporation
  • Linical Korea
Industry
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • The proportion of subjects that the mean Sitting Diastolic Blood Pressure(siSBP) and Low Density Lipoprotein-Cholesterol(LDL-C) level reach the treatment goals after 8 weeks from investigational product administration.
  • Change of Low Density Lipoprotein-Cholesterol(LDL-C) from baseline to 4 and 8 weeks
  • Change of Sitting Systolic Blood Pressure(siSBP) and Sitting Diastolic Blood Pressure(siDBP) from baseline to 4 and 8 weeks
  • (and 3 more…)
204 All 19 Years to 79 Years   (Adult, Senior) NCT02968160 YMC017 October 2016 May 2018 July 2018 November 18, 2016 May 31, 2017
  • Dongguk University Medical Center
    Ilsan, Korea, Republic of
31 NCT01681810 Recruiting Oral Nitrite in Adults With Metabolic Syndrome and Hypertension
  • Metabolic Syndrome
  • Hypertension
  • Drug: 14 N Sodium Nitrite
Interventional Phase 2 Other
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • Change in insulin sensitivity (i.e. insulin stimulated glucose disposal)
  • Change in systolic blood pressure
  • Change in mean arterial pressure
  • (and 2 more…)
20 All 18 Years to 60 Years   (Adult) NCT01681810 PRO11030131 ONTX October 2012 December 2017 September 10, 2012 July 25, 2017
  • Montefiore Hospital of UPMC
    Pittsburgh, Pennsylvania, United States
32 NCT03160755 Recruiting Motivation-Audit-Positive Psychology Intervention Study Observational
  • Massachusetts General Hospital
Other
  • Observational Model: Other
  • Time Perspective: Other
  • Qualitative Data
  • Dispositional Optimism
  • Positive Affect
  • (and 6 more…)
20 All 18 Years to 100 Years   (Adult, Senior) NCT03160755 2016P002824 MAPP-I April 18, 2017 October 8, 2017 October 8, 2017 May 19, 2017 June 8, 2017
  • Massachusetts General Hospital
    Boston, Massachusetts, United States
33 NCT02912325 Recruiting Non-Comparative Study to Assess the Efficacy and Safety of the New Food Supplement FaseMETS
  • Dietary Supplement: Daily administration: 2 tablets FaseMETS a day
Interventional
  • MDM S.p.A.
  • Opera Contract Research Organization SRL
Other
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Other
  • Serum lipidemic profile evaluated at 6 months
  • Serum lipidemic profile evaluated at 3 months
  • AE/SAE (with particular regards for gastrointestinal symptoms)
20 All 45 Years to 70 Years   (Adult, Senior) NCT02912325 OPMDM/0216/FS May 15, 2017 October 15, 2017 June 2018 September 23, 2016 January 15, 2018
  • Opera Contract Research Organization SRL
    Timisoara, Timis, Romania
  • Scm Dr Rosu
    Timişoara, Timis, Romania
34 NCT03081598 Recruiting Study to Evaluate Safety, Efficacy of PBI-4050 & Its Effect on Relevant Biomarkers in T2DM Patients With Metabolic Syndrome
  • Type 2 Diabetes Mellitus
  • Metabolic Syndrome
  • Drug: PBI-4050
  • Other: Placebo
Interventional Phase 2
  • ProMetic Pharma SMT Limited
Industry
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment
  • To evaluate the safety of PBI-4050 400 mg, 800 mg, and 1200 mg as assessed by the number of subjects with abnormal laboratory values and/or adverse events that are related to treatment
  • To evaluate the efficacy of PBI-4050 400 mg, 800 mg, and 1200 mg
  • Change from baseline on diabetic biomarkers
  • (and 2 more…)
268 All 18 Years and older   (Adult, Senior) NCT03081598 PBI-4050-CT-9-08 May 29, 2017 February 2018 March 2018 March 16, 2017 July 13, 2017
  • C-Health
    Edmonton, Alberta, Canada
  • Omnispec Clinical Research
    Mirabel, Quebec, Canada
  • LMC Clinical Research Inc.
    Barrie, Canada
  • (and 8 more…)
35 NCT02406664 Recruiting The Effect of Bariatric/Metabolic Surgery on GFR
  • Procedure: Bariatric surgery
Interventional Other
  • Allocation: Non-Randomized
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Change in Glomerular filtration rate
  • Change in excessive body weight
  • Systolic function (EF)
  • (and 4 more…)
30 All 18 Years to 60 Years   (Adult) NCT02406664 January 2015 December 2016 December 2017 April 2, 2015 February 19, 2016
  • Hanyang University Hospital
    Seoul, Korea, Republic of
36 NCT03251716 Recruiting Berberine Treat Metabolic Syndrome in Schizophrenia
  • Metabolic Syndrome
  • Female
  • Schizophrenia
Interventional Other
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • Change of FBG
  • Change of TG
  • Change of LDL
  • (and 2 more…)
30 Female 18 Years to 60 Years   (Adult) NCT03251716 Ber-open-2015-TJAH January 1, 2015 September 30, 2017 September 30, 2017 August 16, 2017 August 29, 2017
  • Tianjin Anding Hospital
    Tianjin, Tianjin, China
37 NCT02936687 Recruiting Mechanisms of Cerebrovascular Control
  • Drug: NOS Inhibition
  • Drug: ET-1 Inhibition
  • Drug: Placebo
  • (and 3 more…)
Interventional Phase 1
  • University of Wisconsin, Madison
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Basic Science
  • Change in cerebrovascular blood flow in response to NOS inhibition.
  • Change in cerebrovascular blood flow in response to ET-1 inhibition.
60 All 18 Years to 45 Years   (Adult) NCT02936687 2015-0197 January 31, 2017 December 2018 December 2018 October 18, 2016 August 18, 2017
  • University of Wisconsin, Madison
    Madison, Wisconsin, United States
38 NCT02689661 Recruiting Impact of the Metabolic Syndrome on the Incidence of Neuropathy in Obese Subjects
  • Metabolic Syndrome
  • Obesity
  • Neuropathy
Observational
  • Brian Callaghan
  • University of Michigan
Other
  • Observational Model: Cohort
  • Time Perspective: Prospective
  • Neurologist history and examination for presence of neuropathic symptoms, abnormal sensory examination findings, and abnormal reflexes (no specific instrument)
  • Nerve fiber density at the leg
  • Sural sensory nerve conduction amplitude
  • (and 2 more…)
230 All 18 Years and older   (Adult, Senior) NCT02689661 NINDS-NS079417 November 2010 July 2019 July 2019 February 24, 2016 December 25, 2017
  • University of Michigan
    Ann Arbor, Michigan, United States
39 NCT02295202 Recruiting Impact of Obstructive Sleep Apnea Treatment in Patients With Metabolic Syndrome
  • Sleep Apnea
  • Metabolic Syndrome
  • Device: CPAP (REMstar System One Plus – Philips Medical Systems)
  • Device: Nasal strips
Interventional Phase 4
  • University of Sao Paulo
  • Fleury
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Outcomes Assessor)
  • Primary Purpose: Treatment
  • Reversibility of Metabolic Syndrome criteria
  • Abdominal fat
  • Hepatic steatosis
  • (and 8 more…)
100 All 18 Years to 70 Years   (Adult, Senior) NCT02295202 SDC 4075/14/055 TREATOSA-MS March 2015 June 2017 December 2017 November 20, 2014 October 4, 2016
  • Luciano Drager
    Sao Paulo, Brazil
40 NCT03019796 Recruiting Exercise Training Effects on Metabolic Syndrome: Interactions With Medication
  • Exercise Therapy
  • Metabolic Syndrome X
  • Cardiorespiratory Fitness
  • Behavioral: EXERCISE TRAINING
  • Behavioral: NO EXERCISE TRAINING
Interventional
  • University of Castilla-La Mancha
  • Spanish Ministry of Economy and Competitiveness
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • Brachial artery systolic and diastolic pressures.
  • Waist perimeter.
  • Fasting blood level of glucose, cholesterol HDL, triglycerides, glycosylated hemoglobin and protein C reactive.
  • (and 7 more…)
160 All 18 Years to 65 Years   (Adult) NCT03019796 0112001154 DEP2014-52930-R METSYND July 2015 June 2017 August 2018 January 13, 2017 May 9, 2017
  • University of Castilla-La Mancha (Exercise Physiology Lab)
    Toledo, Spain
41 NCT02858102 Recruiting Impact of Aerobic Exercise on Metabolic Syndrome, Neurocognition and Empowerment in Individuals With Mental Disorders
  • Metabolic Syndrome
  • Mental Disorders
  • Behavioral: Physical activity program
Interventional
  • Fundación Marques de Valdecilla
  • Centro de Investigación Biomédica en Red de Salud Mental
  • Instituto de Investigación Marqués de Valdecilla
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Supportive Care
  • Change in abdominal obesity measured by waist circumference
  • Change in dyslipidemia measured by serum triglycerides and/or high-density lipoprotein (HDL cholesterol) levels.
  • Change in hypertension measured by blood pressure
  • (and 2 more…)
50 All 35 Years to 50 Years   (Adult) NCT02858102 EXERTMG EXERTMG June 2016 December 2017 December 2018 August 8, 2016 March 14, 2017
  • University Hospital Marqués de Valdecilla
    Santander, Cantabria, Spain
42 NCT02695186 Recruiting Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome
  • Intestinal Metaplasia
  • Metabolic Syndrome
  • Oxidative Stress
  • Inflammatory Response
Observational
  • General Hospital of Filiates
  • University of Ioannina
Other
  • Observational Model: Case Control
  • Time Perspective: Prospective
  • 8-epiPGF2α (pg/ml)
  • 8-OHG (ng/ml)
  • Total antioxidant capacity (TAC) (mM)
  • (and 8 more…)
180 All 25 Years to 75 Years   (Adult, Senior) NCT02695186 1/21/01/2016 February 2016 February 2016 June 2016 March 1, 2016 March 1, 2016
  • General Hospital of Filiates
    Filiates, Epirus, Greece
43 NCT03059355 Not yet recruiting Intravenous Infusion of Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Bone Marrow (BM) Derived MSCs to Evaluate Cytokine Suppression in Patients With Chronic Inflammation Due to Metabolic Syndrome.
  • Endothelial Dysfunction
  • Metabolic Syndrome
  • Chronic Inflammation
  • Biological: UCMSCs
  • Biological: BMMSCs
  • Other: Placebo
Interventional Phase 1
Phase 2
  • Joshua M Hare
  • University of Miami
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Treatment
  • Incidence of any treatment-emergent serious adverse events (TE-SAEs)
  • Change of inflammatory markers
  • Effect on Frailty Phenotype Score
  • (and 4 more…)
37 All 21 Years to 85 Years   (Adult, Senior) NCT03059355 20170095 CERES March 2018 June 2025 June 2026 February 23, 2017 September 26, 2017
  • ISCI / University of Miami Miller School of Medicine
    Miami, Florida, United States
44 NCT03182985 Recruiting The Impact of Time Restricted Feeding (TRF) in Improving the Health of Patients With Metabolic Syndrome
  • Weight Loss
  • Metabolic Syndrome
  • Overweight and Obesity
  • Behavioral: Time Restricted Feeding
Interventional
  • University of California, San Diego
  • Salk Institute for Biological Studies
  • American College of Cardiology
  • UCSD Public Health Institute
Other
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Prevention
  • Mean blood glucose
  • Insulin level
  • Triglycerides
  • High-sensitivity C-reactive protein
100 All 30 Years to 60 Years   (Adult) NCT03182985 UCSD IRB 170504 July 28, 2017 June 2018 June 2019 June 9, 2017 November 8, 2017
  • UCSD
    La Jolla, California, United States
45 NCT02430987 Recruiting Prevalence of Metabolic Syndrome in Postmenopause Woman With Hypoactive Sexual Desire Disorder
  • Menopause
  • Metabolic Syndrome
  • Hypoactive Sexual Desire Disorder
Interventional
  • Faculdade de Ciências Médicas da Santa Casa de São Paulo
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Other
  • Allocation: Non-Randomized
  • Intervention Model: Single Group Assignment
  • Masking: None (Open Label)
  • Primary Purpose: Prevention
  • application of questionnaire
200 Female 40 Years to 65 Years   (Adult) NCT02430987 40594814.4.0000.5479 September 2014 June 2017 August 2017 April 30, 2015 May 15, 2017
  • Faculdade de Ciências Médicas da Santa Casa de São Paulo
    São Paulo, Brazil
46 NCT03056937 Recruiting Effects of Bariatric Surgery on Inspiratory Metaboreflex in Obese Subjects
  • Obesity
  • Metabolic Syndrome
  • Other: Bariatric surgery
  • Other: Control
Observational Other
  • Observational Model: Case-Control
  • Time Perspective: Prospective
  • Inspiratory metaboreflex
  • Pulmonary function
  • Respiratory muscle strength
  • (and 4 more…)
45 All 18 Years to 45 Years   (Adult) NCT03056937 CAAE: 51573315.7.0000.5322 February 1, 2016 December 1, 2017 December 1, 2018 February 17, 2017 February 17, 2017
  • University of Cruz Alta
    Cruz Alta, Rio Grande do Sul, Brazil
47 NCT03201068 Recruiting Probiotic Supplement and Microbiome, Immune System and Metabolic Syndrome
  • Metabolic Syndrome
  • Microbiome
  • Immune Function
  • Inflammation
  • Dietary Supplement: Probiotic supplement
  • Dietary Supplement: Placebo
Interventional
  • Stanford University
  • The Clorox Company
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Primary Purpose: Prevention
  • Metabolic syndrome parameters: Waist Circumference, Blood pressure, Triglycerides, HDL-cholesterol, and Fasting Glucose.
  • Microbiota composition
  • Microbiota metabolites
  • (and 3 more…)
45 All 18 Years and older   (Adult, Senior) NCT03201068 41697 September 14, 2017 September 30, 2018 September 30, 2018 June 28, 2017 September 26, 2017
  • Stanford University
    Stanford, California, United States
48 NCT02610322 Not yet recruiting Whole Soy Replacement Diet on Metabolic Features
  • Behavioral: Whole soy replacement diet
  • Behavioral: usual diet
Interventional
  • Chinese University of Hong Kong
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Single (Outcomes Assessor)
  • Primary Purpose: Prevention
  • Changes of metabolic components of MetS (body weight, waist circumference, blood pressure, serum lipids and fasting glucose).
  • Changes of 10-year risk for ischemic cardiovascular disease (ICVD)
208 Female 45 Years to 70 Years   (Adult, Senior) NCT02610322 CRE-2013.121 June 2016 December 2017 December 2018 November 20, 2015 November 20, 2015
49 NCT02517697 Not yet recruiting Oral Nitrite Trial for Hypertension and Metabolic Syndrome
  • Metabolic Syndrome
  • Hypertension
  • Drug: 14 Nitrogen (N) Sodium Nitrite
  • Drug: Placebo
Interventional Phase 2
  • Gladwin, Mark, MD
  • University of Pittsburgh
Other
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Triple (Participant, Investigator, Outcomes Assessor)
  • Primary Purpose: Treatment
  • Change in insulin sensitivity (i.e. insulin stimulated glucose disposal)
  • Change in systolic blood pressure
  • Change in mean arterial pressure
  • (and 2 more…)
40 All 18 Years to 60 Years   (Adult) NCT02517697 PRO15050540 ONPC January 2018 June 2020 June 2020 August 7, 2015 July 26, 2017
  • Montefiore Hospital of UPMC
    Pittsburgh, Pennsylvania, United States
50 NCT02034435 Recruiting Endogenous Renin-Angiotensin-Aldosterone System and Glucose Metabolism
  • Other: glucose and insulin testing
Interventional
  • Vanderbilt University
  • Vanderbilt University Medical Center
Other
  • Allocation: Randomized
  • Intervention Model: Crossover Assignment
  • Masking: Double (Participant, Investigator)
  • Primary Purpose: Basic Science
  • Insulin secretion
  • Insulin sensitivity
57 All 18 Years to 70 Years   (Adult, Senior) NCT02034435 131139 October 2013 December 2018 December 2018 January 13, 2014 September 14, 2017
  • Vanderbilt University Medical Center
    Nashville, Tennessee, United States
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