Breaking News
February 23, 2019 - Acupuncture Could Help Ease Menopausal Symptoms
February 23, 2019 - Researchers use AI to detect early signs of Alzheimer’s
February 23, 2019 - On recovery, vulnerability and ritual: An exhibit in white | News Center
February 23, 2019 - Memory Stored in Unexpected Region of the Brain
February 23, 2019 - Several health experts worldwide gather at EUDONORGAN event
February 23, 2019 - Discovery of potent compound in native California shrub may lead to treatment for Alzheimer’s
February 22, 2019 - Researchers create new map of the brain’s own immune system
February 22, 2019 - ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses’ role in antibiotic stewardship
February 22, 2019 - UK Research and Innovation invests £200 million to create new generation of AI leaders
February 22, 2019 - Takeda collaboration to boost fight against Alzheimer’s and other neurodegenerative diseases
February 22, 2019 - Heavy drinking may change DNA, leading to increased craving for alcohol
February 22, 2019 - U.S. opioid deaths jump fourfold in 20 years; epidemic shifts to Eastern states | News Center
February 22, 2019 - 5 Questions with William Turner on Diversity in Medicine
February 22, 2019 - HHS Finalizes Rule Seeking To Expel Planned Parenthood From Family Planning Program
February 22, 2019 - Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer’s
February 22, 2019 - Biologist uses new grant to find ways to eliminate schistosomiasis
February 22, 2019 - Bag-mask ventilation to help patients breathe during intubation prevents complications
February 22, 2019 - AbbVie Announces New Drug Application Accepted for Priority Review by FDA for Upadacitinib for Treatment of Moderate to Severe Rheumatoid Arthritis
February 22, 2019 - Nature versus nurture and addiction
February 22, 2019 - New website connects researchers with data experts, resources | News Center
February 22, 2019 - Today’s Concerns About Drug Prices Echo The Past
February 22, 2019 - CT and Doppler equipment have low accuracy in detecting cerebral vasospasm and ischemia
February 22, 2019 - Study finds out similarity in function between healthy retina cell and tumor cell
February 22, 2019 - CWRU awarded NIH grant to identify effective treatments for intimate partner violence
February 22, 2019 - Oncotype DX Not Cost-Effective for Low-Risk Breast Cancer
February 22, 2019 - Scientists discover new type of immune cells that are essential for forming heart valves
February 22, 2019 - Talk About Déjà Vu: Senators Set To Re-Enact Drug Price Hearing Of 60 Years Ago
February 22, 2019 - Genetic defect linked to pediatric liver disease identified
February 22, 2019 - New cellular atlas could provide a deeper insight into blinding diseases
February 22, 2019 - Growing number of cancer survivors, fewer providers point to challenge in meeting care needs
February 22, 2019 - Innovative compound offers a new therapeutic approach to treat multiple sclerosis
February 22, 2019 - $1.5 million grant to develop opioid treatment program for jail detainees
February 22, 2019 - FDA’s new proposed rule would update regulatory requirements for sunscreen products in the U.S
February 22, 2019 - Most Hip, Knee Replacements Last Decades, Study Finds
February 22, 2019 - Wellness problems prevalent among ob-gyn residents
February 22, 2019 - In the Spotlight: “The world is your oyster in geriatrics”
February 22, 2019 - Successful testing of multi-organ “human-on-a-chip” could replace animals as test subjects
February 22, 2019 - Analysis of cervical precancer shows decline in two strains of HPV
February 22, 2019 - Sugary stent eases suturing of blood vessels
February 22, 2019 - From surgery to psychiatry: A medical student reevaluates his motivations
February 22, 2019 - Is New App From Feds Your Answer To Navigating Medicare Coverage? Yes And No
February 22, 2019 - New pacemakers powered by heartbeats could reduce need for surgery
February 22, 2019 - The United States records highest drug overdose death rates
February 22, 2019 - Morning walks could be better than drugs at lowering blood pressure
February 22, 2019 - Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy
February 22, 2019 - Vitamin D supplementation less effective in the presence of obesity, shows study
February 22, 2019 - Novostia raises CHF 6.5 million to advance its aortic, mitral heart valve to clinical trials
February 22, 2019 - CPRIT awards nearly $20 million to The University of Texas MD Anderson Cancer Center
February 22, 2019 - Sarepta Announces FDA Acceptance of Golodirsen (SRP-4053) New Drug Application for Patients with Duchenne Muscular Dystrophy Amenable to Skipping Exon 53
February 22, 2019 - An institutional effort to reduce the amount of opioids prescribed following lumbar surgery
February 22, 2019 - Family-history-based models perform better than non-family-history based models
February 22, 2019 - Failure to take statins leads to higher mortality rates | News Center
February 22, 2019 - New study explains why some patients report phantom sensations after limb amputation
February 22, 2019 - First motor-controlled heart valves implanted by Mainz University Medical Center
February 22, 2019 - Novel preclinical model mimics persistent interneuron loss seen in preterm infants
February 22, 2019 - Global health burden of glaucoma has increased, study reveals
February 22, 2019 - A holistic approach key to minimize treatment complexity in patients with interstitial lung disease
February 22, 2019 - 1 in 10 middle-aged Chinese adults are at high risk for heart disease, finds study
February 22, 2019 - More than half a million breast cancer patient’s lives saved by improvements in treatment
February 22, 2019 - Study finds no evidence that tougher policies prevent teenage cannabis use
February 22, 2019 - New blood test detects genetic disorders in fetuses
February 22, 2019 - Lower Self-Perception Observed in Children With Amblyopia
February 22, 2019 - Up to 15 percent of children have sleep apnea, yet 90 percent go undiagnosed
February 22, 2019 - Rare pulmonary defect prompts parents’ nationwide search for answers | News Center
February 22, 2019 - Lesbian and bisexual women at greater risk of being overweight, study finds
February 22, 2019 - UQ research may explain why vitamin D is essential for brain health
February 22, 2019 - Heart Attacks Rising Among Younger Women
February 22, 2019 - How your smartphone is affecting your relationship
February 22, 2019 - Orthopaedic surgeon receives prestigious award, $10 million grant | News Center
February 22, 2019 - New sepsis test could save thousands of lives
February 22, 2019 - Cervical cancer could be eradicated by 2100
February 21, 2019 - Sustained smoking cessation can lower risk of seropositive RA
February 21, 2019 - Thousands with chronic UTIs are not receiving the treatment they need
February 21, 2019 - Are teens getting high on social media? The surprising study seeking the pot-Instagram link
February 21, 2019 - Stanford expands biobank services | News Center
February 21, 2019 - Scientists identify link between drinking contexts and early onset intoxication among adolescents
February 21, 2019 - Strong social support may reduce cardiovascular disease risk in postmenopausal women
February 21, 2019 - Rapid expansion of interventions could prevent up to 13 million cases of cervical cancer within 50 years
February 21, 2019 - Motif Bio Receives Complete Response Letter From The FDA
February 21, 2019 - Researchers map previously unknown disease in children
Reducing the prevalence of overweight, obesity in Canada could prevent cumulative cancer cases

Reducing the prevalence of overweight, obesity in Canada could prevent cumulative cancer cases

image_pdfDownload PDFimage_print

Reducing the number of overweight and obese Canadians by 50 percent could potentially prevent a cumulative 59,829 cases of cancer by 2042, according to estimates presented at the American Association for Cancer Research Special Conference Obesity and Cancer: Mechanisms Underlying Etiology and Outcomes, held Jan. 27-30.

“Cancer is the leading cause of death in Canada, and several cancer types have strong associations with excess body weight; yet the number of Canadians who are overweight or obese is increasing,” said Darren Brenner, PhD, assistant professor in the departments of Oncology and Community Health Sciences at Cumming School of Medicine, University of Calgary, Alberta, Canada.

Brenner is part of a collaborative group from multiple institutions across Canada working together on the Canadian Population Attributable Risk of Cancer Project (ComPARe). The goal of this project is to estimate how many new cases of cancer are caused by 25 different risk factors, including lifestyle factors such as diet, body size, and physical activity, and how many could be avoided over the next 30 years if changes in behaviors were made, Brenner said.

Using population-level data and statistical approaches, Brenner and colleagues first projected the number of Canadians with excess body weight (overweight plus obesity) over the next 30 years. They found that in 2011, the prevalence of overweight and obesity in Canada was 32.7 percent and 17.8 percent, respectively.

“If current trends continue, by 2032, the prevalence of overweight and obesity will be 31.2 percent and 27.9 percent, respectively,” Brenner noted.

Using data from 2012, the researchers estimated that 8,626 cancer cases (3,886 for men and 4,740 for women) were attributable to excess body weight, accounting for 9.4 percent of the 91,373 associated cancer cases (8.8 percent for men and 10.1 percent for women). The researchers then projected that in 2042, 15,747 cancer cases for men and 10,312 cancer cases for women would be attributable to excess body weight, accounting for 10.8 percent of the 146,260 associated cancer cases in men and 11.2 percent of the 92,233 associated cancer cases in women.

“After projecting the future prevalence of excess body weight and cancer incidence attributable to excess body weight, we asked how the trends in excess body weight could be influenced by effective interventions,” said Brenner.

The team studied scenarios of interventions that would reduce the prevalence of excess body weight by 10, 25, and 50 percent by 2042 and then estimated the cancer burden under these new scenarios. “The difference in cancer incidence between our projected data and our ‘prevention’ scenarios would be the future potential for cancer prevention,” Brenner explained. The scenarios were meant to simulate population-level implementation of existing intervention programs, policy changes to impact healthy behavior decision making, or a return to obesity levels in 1990.

The researchers found that if it is possible to intervene on excess body weight and reduce the prevalence of both overweight and obesity by 10, 25, and 50 percent, it would be possible to prevent 1,660, 4,150, and 8,300 cancer cases in 2042, and a cumulative number of 11,966, 29,914, and 59,829 cancer cases by 2042, respectively.

“Our data provide alarming estimates of the consequences of inaction in Canada,” Brenner said. “The results of this study will inform policymakers, public health officials, and the Canadian population with targets to lower future cancer burden.”

According to Brenner, limitations of the study are that the estimates of overweight and obesity used in this study were based on self-reported data, and that the researchers assumed a latency period of 10 years between exposure to a risk factor and cancer diagnosis, which is a potential over-simplification since the latency period for some exposures is longer.

Source:

http://www.aacr.org/Newsroom/Pages/News-Release-Detail.aspx?ItemID=1143

Tagged with:

About author

Related Articles