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ID Break: Herpes Down in U.S.; $500 Billion Pandemics; Deadly Dengue Vax?

ID Break: Herpes Down in U.S.; $500 Billion Pandemics; Deadly Dengue Vax?

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This flu season is now on par with the last ‘high severity’ flu season, as the CDC announced record hospitalization numbers so far. Check out MedPage Today for more coverage, and stay tuned for another flu update at the end of the week.

In 2015-2016, prevalence of herpes declined in the U.S. among younger adults compared to 1999-2000, though prevalence of herpes simplex virus type 1 and type 2 increased with age and was higher among women than men. (NBC News)

Researchers found organisms that were resistant to “last-resort” antibiotics in hospital pipes and sewers. (mBio)

Investigational, non-replicating smallpox vaccine, Imvamune (Bavarian Nordic A/S) announced positive phase III trial results, and is expected to file with the FDA for approval in second half of 2018. (Global Newswire)

The World Health Organization estimated the losses from a global pandemic would be $500 billion per year.

A lower portion of African Americans compared to Latinos and whites had sustained viral suppression through proper treatment of HIV infection. Overall, fewer than half of HIV infections in from states reporting data were “consistently under control.” (Morbidity and Mortality Weekly Report)

A preliminary report from one hospital in the Philippines found a potential link between dengue vaccine, Dengvaxia (Sanofi) and three deaths, but is still investigating the cases. (FiercePharma)

A Cochrane review found that a single dose of primaquine added to malaria treatment stopped people from infecting mosquitoes with malaria, thus reducing transmission.

Vaccines not only play a role in health, they may help keep people out of medical impoverishment in low and middle-income countries. (Health Affairs)

India may be contributing to the problem of global antimicrobial resistance by selling unapproved antibiotics. (British Journal of Clinical Pharmacology)

Genetics may play a role in which babies are affected by congenital Zika virus syndrome. (Nature Communications)

Aradigm said its inhaled steroid, Linhaliq, was not approved by the FDA to treat non-cystic fibrosis bronchiectasis in patients with chronic lung infections caused by Pseudomonas aeruginosa, with the agency citing concerns about “clinical data, product quality” and the need for a human factors study.

Could West Nile virus and Powassan virus, a rare virus spread by ticks, cause fetal brain damage similar to the Zika virus? A mouse study says yes. (Science Translational Medicine)

2018-02-07T12:00:00-0500

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