Breaking News
April 23, 2018 - Eating fish could prevent Parkinson’s disease
April 23, 2018 - Key factor in development of Parkinson’s disease identified
April 23, 2018 - Higher consumption of fish linked to better neurological health
April 23, 2018 - Genevac announces HT Series 3 evaporators with Inert Gas Purge option
April 23, 2018 - Researchers clarify immune response for patients with breast cancer brain metastases
April 23, 2018 - Polypharmacy More Likely for Cancer Survivors
April 23, 2018 - Obesity is shifting cancer to young adults
April 23, 2018 - Scientists illustrate role of novel chromosomal mutations in fosfomycin resistance
April 23, 2018 - Newly developed drug compound may help treat Charcot-Marie-Tooth disease
April 23, 2018 - Marriage Means ‘I Do’ for Skin Cancer Detection
April 23, 2018 - Freezing hunger-signaling nerve may help ignite weight loss
April 23, 2018 - Wear exoskeletons with caution for heavy lifting, researchers say
April 23, 2018 - Research offers new hope for healing wounds in patients with diabetes
April 23, 2018 - Shorter courses of radiotherapy found to be safe, effective for prostate cancer patients
April 23, 2018 - Scientists use CRISPR tool to make multiple edits to DNA samples ‘in vitro’
April 23, 2018 - Knee reconstructions are on the rise among the youth in Australia
April 23, 2018 - Artificial sweeteners linked to obesity warn researchers
April 23, 2018 - CDC seeking $400 million to replace lab for deadliest germs
April 23, 2018 - Sensirion to present single-use liquid flow sensor at COMPAMED 2017
April 23, 2018 - FDA approves contact lenses that shade the sun
April 22, 2018 - Concussion recovery and symptom severity found to vary between men and women
April 22, 2018 - C. Difficile Risk Higher With Stoma Reversal Versus Colectomy
April 22, 2018 - Repeated ranibizumab doesn’t impair macular perfusion
April 22, 2018 - New microscope reveals how cells behave in 3D and real time inside living organisms
April 22, 2018 - Study shows clinical benefit and monetary gains of weight-loss surgery
April 22, 2018 - GNA Biosolutions launches world’s first Laser PCR platform at Medica Trade Fair
April 22, 2018 - Researchers present simulation model to investigate hospital responsiveness to mass casualty incidents
April 22, 2018 - Does Pot Really Dull a Teen’s Brain?
April 22, 2018 - Controversial pregnancy test drug shows deformities in zebrafish embryos within hours of exposure
April 22, 2018 - New research partnership makes childbirth safer in Mozambique
April 22, 2018 - Brief bedside visual art intervention reduces pain, anxiety in cancer patients
April 22, 2018 - The memory part of the brain may also hold clues for anxiety and depression
April 22, 2018 - AYOXXA to develop multiplex immunoassay to support treatment of sepsis patients
April 22, 2018 - New Drug Combo Ups Survival in HER2/neu Uterine Serous Cancer
April 22, 2018 - Researchers chart a new way to look at concussion
April 22, 2018 - Every parent needs to know fundamental red flags for autism
April 22, 2018 - Anatotemp expands anatomic dental implant healing abutments with 4Side anti-rotational connection
April 22, 2018 - Gene Twist Can Make Your Blood Pressure Spike From Salt
April 22, 2018 - Study suggests failed osteoarthritis drug could help treat opioid addiction
April 22, 2018 - More Americans aware of growing problem of opioid addiction
April 22, 2018 - KHN’s ‘What the Health?’ Nothing in health care ever goes away
April 22, 2018 - BGS to promote high-quality sterilization services at Health GB in Manchester
April 22, 2018 - New integrated POC tool detects biomarkers of heart failure rapidly and precisely
April 22, 2018 - Direct electrical current can be delivered to nerves for blocking pain signals
April 22, 2018 - Newly Published Phase 2 Study Found Esketamine Demonstrated Significantly Rapid Improvements in Depressive Symptoms and Suicidality
April 22, 2018 - Healthy red blood cells owe their shape to muscle-like structures
April 22, 2018 - Researchers present case study of management of rheumatic mitral regurgitation in woman contemplating pregnancy
April 22, 2018 - New black Porvair Krystal UV Quartz microplates for Circular Dichroism measurements
April 22, 2018 - Advanced flow chemistry modules enhance control of nanoprecipitation
April 22, 2018 - Look! Down in the petri dish! It’s a superplatelet!
April 22, 2018 - Research reveals why people with tetraplegia more likely to suffer from sleep apnea
April 21, 2018 - New non-invasive nerve stimulation may offer relief for people with hand tremor
April 21, 2018 - Smartphone App May Up Medication Adherence in HTN
April 21, 2018 - Western diet depletes artery-protecting immune cells
April 21, 2018 - Excelitas Technologies launches new powerful LED light source for fluorescence microscopy
April 21, 2018 - Academia and high tech companies join forces to increase production capacity for microfluidic systems
April 21, 2018 - Developing cooking skills as young adult may have long-term health benefits
April 21, 2018 - Study compares survival outcomes of different drugs for type 2 diabetes
April 21, 2018 - More Than 40 Percent of Americans Breathe Dirty Air: Report
April 21, 2018 - Obstructive sleep apnea – Genetics Home Reference
April 21, 2018 - More evidence shows exposure to traffic and outdoor air pollution increases risk of asthma
April 21, 2018 - Novel gold nanoparticle technology could guide cancer treatment in real-time
April 21, 2018 - News coverage of Ebola impacted public’s perception on disease and survivors
April 21, 2018 - S.Africa’s DIY battle against HIV
April 21, 2018 - Children with autism have gastrointestinal and immune system deregulation, research finds
April 21, 2018 - Human brain processes sight and sound in the same way, shows study
April 21, 2018 - Evolutionary history of tumor helps predict severity of prostate cancer
April 21, 2018 - Pepper plant metabolizes antibiotic in personal care products
April 21, 2018 - Tradeshow Talks with Integra
April 21, 2018 - EPFL becomes part of Chan Zuckerberg’s project to develop Human Cell Atlas
April 21, 2018 - Pfizer Announces Positive Topline Results From Phase 3 ATTR-ACT Study Of Tafamidis In Patients With Transthyretin Cardiomyopathy
April 21, 2018 - Breaking through the HIV vaccine ‘logjam’
April 21, 2018 - IntelliCyt introduces new QSol buffer to enable robust, consistent sampling
April 21, 2018 - Scientists publish comprehensive lineage tree of whole adult animal in Science journal
April 21, 2018 - Innovative method based on FluidFM technology could revolutionize biological research
April 21, 2018 - Americans world’s biggest TV addicts, watching four hours a day
April 21, 2018 - Investigational drug may help increase protein levels in babies with spinal muscular atrophy
April 21, 2018 - Study shows distinctions between age groups in predicting and responding to stress at home
April 21, 2018 - Aziyo Biologics, BIOTRONIK enter into US co-distribution agreement
April 21, 2018 - Opiate Use Linked to Early Mortality in IBD Patients
OHSU, CDC physicians treat first known case of woman infected with cattle eyeworm

OHSU, CDC physicians treat first known case of woman infected with cattle eyeworm

image_pdfDownload PDFimage_print

An August 2016 call to an infectious disease hotline OHSU runs for Northwest physicians ended up being one for the record books.

Erin Bonura, M.D., assistant professor of medicine (infectious disease) at the OHSU School of Medicine, heard this on the other end of the line:

“‘This patient has worms coming out of her eye. What are we going to do?’,” Bonura recalled. “That’s one of the more unique calls I’ve received.”

The patient, then a 26-year-old woman from Brookings, Oregon, ended up being the first-ever known case of the nematode worm Thelazia gulosa, a type of cattle eyeworm, infecting a human.

A paper published in the American Journal of Tropical Medicine and Hygiene describes the odd infection. The paper’s lead author is Richard S. Bradbury, Ph.D., of the CDC’s Parasitic Diseases Branch, who did some serious sleuthing with Bonura and others to identify the unwelcome worm.

Worms in the family Thelazia are a common parasite in North American cattle, but are rarely spread to humans. Before this case, there were just 10 known incidences of humans being infected with a Thelazia worm in North America, but none of those cases involved the species gulosa. This was the first case of a person being infected with a Thelazia worm in the U.S. in more than two decades.

The best Bonura and her colleagues can guess is the patient, Abby Beckley, may have been infected while being near cows or horses in the rural fields near her family’s home. The cattle eyeworm is spread from cow to cow by flies that suck on cow tears and pick up worm larvae in the process. One fly carrying cattle eyeworm larvae may have briefly landed on the patient’s eye.

Luckily, the cattle eyeworm can’t easily reproduce in humans — and didn’t in Beckley’s case. However, the deposited larvae did grow into adult worms and begin wriggling around on the surface of the Beckley’s eye. She had recently started work on a fishing boat in Alaska when her eye first began to feel irritated, as if there was an eye lash she couldn’t remove.

While examining her eye, Beckley was able to remove a thin, half-inch-long translucent worm with her fingers. She initially thought it might have been a salmon worm, but she couldn’t find any online reports of people who fish and had worms in their eyes. She saw a few doctors while she was onshore in Alaska, but no one knew what to do.

Frustrated, Beckley cut her fishing stint short and flew home to Oregon. Bonura met her at the OHSU Emergency Department and worked with other OHSU staff to help Beckley find some relief. Unfortunately, Beckley was the most skilled at plucking out her own worms. All in all, 14 worms were removed from Beckley’s eye over the course of a month.

“I was really thankful to be linked up with Dr. Bonura,” Beckley said. “Dr. Bonura was so willing to just talk with me and was really empathetic to what I was going through as the person who had this thing in her eye. I was thankful for her grit and dedication.”

Meanwhile, Bonura was frantically working with the CDC and Northwest Pathology to identify these strange worms, samples of which had been sent to Bradbury’s CDC lab in Atlanta. They narrowed it down to a Thelazia worm in about two weeks, but didn’t realize it was the gulosa species until they were writing their paper months later.

Two and a half years later, Beckley is doing well. She removed the last worm herself on Aug. 30, 2016. Besides being briefly worried when she feels a lash in her eye, she doesn’t have any other lingering effects.

Though infectious diseases can be spread anywhere, another case like this isn’t likely.

“Infections from Thelazia worms mostly happen in animals and humans are just incidental hosts,” Bonura said. “This is incredibly interesting and I’m sure it might make some people squeamish, but it’s not something people should worry about.”

Source:

https://news.ohsu.edu/2018/02/12/ohsu-cdc-unravel-mysterious-eye-infection

Tagged with:

About author

Related Articles