Breaking News
December 10, 2018 - Some Brain Tumors May Respond to Immunotherapy, New Study Suggests
December 10, 2018 - Banning junk food ads to combat childhood obesity
December 10, 2018 - Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality
December 10, 2018 - Largest autism sequencing study to date yields 102 genes associated with ASD
December 10, 2018 - Statins associated with low risk of side effects
December 10, 2018 - Study explores how schools address adolescent self-harming practices
December 10, 2018 - Pregnancy in adolescence linked to increased risks of complications in young mothers
December 10, 2018 - Risk Analysis publishes special issue on communicating about Zika virus
December 10, 2018 - Botox May Help Prevent Post-Op A-Fib
December 10, 2018 - African-American mothers rate boys higher for ADHD
December 10, 2018 - Graphic warning labels cancel out cigarettes’ appeal to young people
December 10, 2018 - Australian researchers to study gas inhalational anaesthetic and likelihood of cancer return
December 10, 2018 - Individual neurons located within the brain have implications for psychiatric diseases
December 10, 2018 - Researchers improve bariatric surgery scoring system to extend prediction time for diabetic remission
December 10, 2018 - HPV type 16 or 18 associated with cervical cancer risk in young women
December 10, 2018 - Cervical cancer risk is higher in women with positive HPV, but no cellular abnormalities
December 10, 2018 - Combo therapy not needed if low RA disease activity achieved
December 10, 2018 - Novel therapeutic targets based on biology of aging show promise for Alzheimer’s disease
December 10, 2018 - UC San Diego professor receives NCI Outstanding Investigator Award for cancer research
December 10, 2018 - Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration
December 10, 2018 - Blueprint Medicines Announces Updated Results from Ongoing EXPLORER Clinical Trial of Avapritinib Demonstrating Broad Clinical Activity and Significant Symptom Reductions in Patients with Systemic Mastocytosis
December 10, 2018 - Study clarifies ApoE4’s role in dementia
December 10, 2018 - Eating disorders now a top priority with Australian Government
December 10, 2018 - Neuronal activity in the brain allows prediction of risky or safe decisions
December 10, 2018 - FDA Alerts Health Care Professionals and Patients Not to Use Drug Products Intended to be Sterile from Promise Pharmacy
December 10, 2018 - Improving dementia care and treatment saves thousands of pounds in care homes
December 10, 2018 - Heroin-assisted treatment can offer benefits, reduce harms
December 10, 2018 - People covered by Michigan’s expanded Medicaid program report improvements in health, finds study
December 10, 2018 - Hazelnuts improve micronutrient levels in older adults
December 9, 2018 - History of Partner Violence Tied to Menopause Symptoms
December 9, 2018 - Clean Up Safely After a Disaster|Natural Disasters and Severe Weather
December 9, 2018 - Drug wholesalers drove fentanyl’s deadly rise, report concludes
December 9, 2018 - Deprescribing could help manage polypharmacy in older adults
December 9, 2018 - Retraction of article “Joy of cooking too much” from journal
December 9, 2018 - FDA Warns of Rare Stroke Risk With MS Drug Lemtrada (Alemtuzumab)
December 9, 2018 - Feds say heroin, fentanyl remain biggest drug threat to US
December 9, 2018 - Eliminating microglia can reverse some aspects of stress sensitization, study shows
December 9, 2018 - New genetic insight could help treat rare debilitating heart and lung condition
December 9, 2018 - MiRagen Therapeutics Announces Final Safety, Biodistribution and Clinical Efficacy Data From Phase 1 Cobomarsen Clinical Trial in Patients With Mycosis Fungoides
December 9, 2018 - Work with your doctor to weigh pros, cons of treatment options for hyperthyroidism
December 9, 2018 - CWRU researcher secures $14.6 million funding for genetic study into Alzheimer’s disease
December 9, 2018 - High intensity statin treatment and adherence could save more lives
December 9, 2018 - Surgery patients use only 1/4 of prescribed opioids, and prescription size matters
December 9, 2018 - AXT offers Phi Optics upgrade to QPI systems for inverted light microscopes
December 9, 2018 - New booklet could help improve conditions of young pupils with albinism
December 9, 2018 - Few Physicians Work in Practices That Use Telemedicine
December 9, 2018 - Older Adults and Oral Health
December 9, 2018 - Health utility values improve after septorhinoplasty
December 9, 2018 - New EU-funded project provides insight into how the brain develops
December 9, 2018 - Expanded use of tele-emergency services can help strengthen rural hospitals
December 9, 2018 - Infections in the Young May Be Tied to Risk for Mental Illness: Study
December 9, 2018 - Profile: Native Hawaiians and Pacific Islanders
December 9, 2018 - Snoring poses greater cardiac risk to women
December 9, 2018 - Researcher takes further steps in understanding how and why cute aggression occurs
December 9, 2018 - Researchers create new light-activated tools for controlling neurons
December 9, 2018 - Spinal cord injury disrupts the body’s internal clock, study shows
December 9, 2018 - Babies recognize nested structures similar to our grammar
December 9, 2018 - UT Austin researcher receives $2.5 million CZI grant for neurodegenerative disease research
December 9, 2018 - Sleep problems found to be prevalent and increasing among college students
December 9, 2018 - Study reveals why some children are susceptible to the effects of maltreatment
December 9, 2018 - Study investigates influence of different opioids on driving performance
December 9, 2018 - Jazz Pharmaceuticals Announces First Patient Enrolled in Phase 3 Clinical Trial Evaluating JZP-258 for the Treatment of Idiopathic Hypersomnia
December 9, 2018 - Eliminating microglia prevents heightened immune sensitivity after stress
December 9, 2018 - Boys with social difficulties are at greatest risk of early substance use
December 9, 2018 - ‘Wrong’ connective tissue cells linked to worse prognosis in breast cancer patients
December 8, 2018 - Chronic, refractory schizophrenia patients benefit from targeted cognitive training
December 8, 2018 - Advertising in kids’ apps more prevalent than parents may realize
December 8, 2018 - New way to trace the transmission histories of rare genetic diseases
December 8, 2018 - ASH: A+CHP Bests CHOP for Peripheral T-Cell Lymphoma
December 8, 2018 - Results of pediatric genomic epilepsy tests often reclassified
December 8, 2018 - New way of controlling HIV latency to completely eradicate the virus
December 8, 2018 - Phasefocus to showcase the Livecyte 2 at ASCB
December 8, 2018 - KHN’s ‘What the Health?’ Is health spending the next big political issue?
December 8, 2018 - Mussels take in microplastic pollution fibers and flush most of them out again
December 8, 2018 - AHA: How to Stop Smoking … for Good
December 8, 2018 - Scientists overturn odds to make Parkinson’s discovery
December 8, 2018 - Health benefits of producing marula vinegar
December 8, 2018 - Failure of critical cellular energy sensor responsible for CKD progression, study finds
December 8, 2018 - Ethnicity can be reliable indicator of gut microbiota diversity
December 8, 2018 - Safe Sleep for Baby | NIH News in Health
It’s Not Your Imagination: You’re Hungrier After Losing Weight

It’s Not Your Imagination: You’re Hungrier After Losing Weight

image_pdfDownload PDFimage_print

WEDNESDAY, Feb. 14, 2018 — If you find yourself famished after you’ve managed to diet away a sizable number of pounds, you’re not alone.

Cutting back on calorie consumption is likely to spark changes that permanently boost appetite among obese men and women, Norwegian researchers report.

Blame it on the hunger hormone ghrelin, which spikes when you suddenly lower your food intake. It’s a phenomenon that harkens back to when early humans had to survive bouts of famine, the researchers said.

Now, that ancestral hormonal swing may undermine long-term efforts to keep the weight off, judging by what happened to 35 morbidly obese patients as they spent two years on a highly structured weight-loss program.

“It is extremely important that both patients with obesity and health professionals working with them are aware of the expected increase in hunger with weight loss,” said study author Catia Martins. “This can explain why it is so difficult, at least for some individuals with obesity, to comply with energy-restricted diets, and why so many give up.”

Martins is an associate professor with the faculty of medicine at the Norwegian University of Science and Technology.

The statistics can be disheartening: The researchers noted that only 1 in 5 obese dieters is able to keep off the weight he or she sheds.

The study focused on 22 women and 13 men in Norway who were about 275 pounds, on average, and characterized as “severely obese,” before embarking on a highly supportive weight-loss program.

First, all underwent a three-week inpatient program that offered nutritional education, psychological counseling and routine exercise activities. Four more three-week sessions were completed over the course of the program.

Throughout, all participants were placed on a “moderately restricted” diet. This meant consuming about 500 calories per day less than otherwise needed to maintain a status quo weight. Food breakdown was set at 50 percent carbs, 30 percent fat and 20 percent protein.

On average, the patients lost about 11 pounds within the first three weeks of the program, and an average of 24 pounds by the two-year mark.

But at both the one and two-year marks all the patients also reported feeling increasing hunger following their weight loss.

Why? On the one hand, as weight went down, ghrelin levels went up and stayed up. On the other, as the participants’ weight dropped their energy needs for basic functions — such as breathing, sleeping, walking and eating — also dropped.

And the result is strong pressure towards regaining lost weight over time, turning weight loss maintenance into a lifelong daily struggle, the researchers said.

The findings were published recently in the American Journal of Physiology-Endocrinology and Metabolism.

Lona Sandon is program director of the department of clinical nutrition with the School of Health Professions at the University of Texas Southwestern Medical Center at Dallas. The study “supports what is already known,” she said.

“And the authors make a great point in regards to obesity treatment/management,” said Sandon, who wasn’t involved with the study. “People need long-term support, and the standard care or payment methods [health insurance] for obesity management are short-term, despite the oodles of evidence for long-term support and support beyond the physician setting.”

Insurance, for example, rarely kicks in to cover the services of a registered dietitian or personal trainer, Sandon noted.

But for those anxious to minimize the hunger hormone trap, Sandon says slow and steady weight loss is the way to go.

“It may take months, six or more, of consistent daily exercise combined with mild calorie restriction, decreasing 200 to 300 calories per day, to reach a lower [hormonal] ‘set point,’ ” she said.

But, “the slower the weight loss, and the more modest the calorie restriction to obtain weight loss, the more likely someone might keep the lost weight off,” she said.

An hour a day of exercise can also help to lower a set point, Sandon added, whether that be time spent on a treadmill or time spent doing “something you enjoyed doing as a kid,” like dancing, playing basketball or soccer, swimming or even roller-skating.

More information

There’s more on the importance of achieving a healthy weight at the U.S. National Heart, Lung, and Blood Institute.

© 2018 HealthDay. All rights reserved.

Posted: February 2018

Tagged with:

About author

Related Articles