Breaking News
April 18, 2019 - Scientists enter research collaboration to find a cure for cancer
April 18, 2019 - Study to compare benefits of tai chi and mindfulness meditation on MS symptoms
April 18, 2019 - Gestational diabetes during pregnancy may increase risk of type 1 diabetes in children
April 18, 2019 - Is a New Remedy for Body Odor on the Horizon?
April 18, 2019 - Orthostatic hypotension – Genetics Home Reference
April 18, 2019 - Healing the heartbreak of stillbirth and newborn death
April 18, 2019 - Conference to highlight advances in human immune monitoring, bioinformatics | News Center
April 18, 2019 - Bacteria use viruses for self-recognition, study reveals
April 18, 2019 - New adhesive patch could help reduce post-heart attack muscle damage
April 18, 2019 - Researchers analyze the effects of dark play in a serious video game
April 18, 2019 - Filial cannibalism and offspring abandonment may be forms of parental care
April 18, 2019 - Two proteins act in concert to maintain a healthy heart in mice, shows study
April 18, 2019 - Scientists create a functioning 3D printed heart
April 18, 2019 - Non-invasive vagus nerve stimulation improves disease symptoms in patients with rheumatoid arthritis
April 18, 2019 - Majority of men struggle to understand diagnosis and treatment of prostate cancer
April 18, 2019 - Researchers create new small molecules that may combat equine encephalitis viruses
April 18, 2019 - Animal-assisted therapy improves social behavior in patients with brain injuries
April 18, 2019 - Some viruses help protect harmful bacteria in CF patients | News Center
April 18, 2019 - Outpatient healthcare providers inappropriately prescribe antibiotics to 40% of patients
April 18, 2019 - Men who have a resting heart rate of 75 bpm are twice as likely to die early
April 18, 2019 - Novel serum biomarkers to detect NAFLD-related fibrosis
April 18, 2019 - New study delves deeper into individual genomic differences than ever before
April 18, 2019 - Gilead and Galapagos Announce Filgotinib Meets Primary Endpoint in the Phase 3 FINCH 3 Study in Methotrexate-Naïve Rheumatoid Arthritis Patients
April 18, 2019 - Emotional mirror neurons found in rats
April 18, 2019 - Sylvia Plevritis appointed chair of biomedical data science | News Center
April 18, 2019 - Yeast strain provides manufacturing boost to low-calorie sweetener derived from lactose
April 18, 2019 - C-Path and CDISC release global Therapeutic Area Standard for HIV research
April 18, 2019 - Integrating AI to analyze imaging data allows early recognition of heart disease
April 18, 2019 - Low-cost, high-speed algorithm may allow animal-free chemical toxicity testing
April 18, 2019 - HPV-negative cervical cancers are more aggressive with worse prognosis
April 18, 2019 - AI detects prostate cancer with same level of accuracy as experienced radiologists
April 18, 2019 - Study resolves sex differences in psychiatric illness risk
April 18, 2019 - Novartis Announces FDA Filing Acceptance and Priority Review of Brolucizumab (RTH258) for Patients with Wet AMD
April 18, 2019 - Cocktail of common antibiotics can fight resistant E. coli
April 18, 2019 - Persis Drell to give keynote address at medical school diploma ceremony | News Center
April 18, 2019 - EpicTogether: Remembering Our Why
April 18, 2019 - Study identifies novel loci contributing to asthma susceptibility in adults
April 18, 2019 - Gut bacteria and pregnancy
April 18, 2019 - New study finds that screening could help prevent rare types of cervical cancer
April 17, 2019 - Spatial orgnization of the genome can be altered using small molecules
April 17, 2019 - AEDs Tied to Higher Pneumonia Risk in Alzheimer Patients
April 17, 2019 - Telemedicine tied to more antibiotics for kids, study finds
April 17, 2019 - Two medical students awarded 2019 Soros Fellowships for New Americans | News Center
April 17, 2019 - Sociologist Constance A. Nathanson Awarded Guggenheim Fellowship
April 17, 2019 - Empathy and hormones could account for aggressive behavior in children, shows study
April 17, 2019 - Researchers develop oral appliance to help sufferers of sleep apnea
April 17, 2019 - Neuronal transport factor detects its target transcripts in more complex manner than previously thought
April 17, 2019 - New drug-delivery system senses high oxidant levels, responds to body chemistry and environment
April 17, 2019 - Health Tip: Horseback Trail Riding Safety
April 17, 2019 - Scientists outline the promises and pitfalls of machine learning in medicine
April 17, 2019 - $12 million grant renewal for flu vaccine research | News Center
April 17, 2019 - Lisa Kachnic, MD, Joins Columbia University as Chair of Radiation Oncology
April 17, 2019 - New study sheds light on how extreme temperature hampers spermatogenesis in insects
April 17, 2019 - Study tests high-tech, non-pharmaceutical way to address ADHD and distractibility
April 17, 2019 - New EZ-2 evaporator for clinical biochemistry sample preparation
April 17, 2019 - Fat shaming celebrities may make women more judgemental about being overweight
April 17, 2019 - Magic mouthwash effectively reduces mouth sore pain caused by radiation therapy
April 17, 2019 - CBD could help slip medications into the brain
April 17, 2019 - Scientists characterize 2017 pneumonic plague outbreak in Madagascar
April 17, 2019 - Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature
April 17, 2019 - Gun Research Is Suddenly Hot
April 17, 2019 - Employee wellness programs provide little health benefits
April 17, 2019 - Cannabis users could be more tolerant to anesthesia agents
April 17, 2019 - Study suggests new approach to treat renal fibrosis
April 17, 2019 - Green roofs may improve indoor air quality, study shows
April 17, 2019 - Selumetinib Granted U.S. Breakthrough Therapy Designation in Neurofibromatosis Type 1
April 17, 2019 - Fasting-mimicking diet holds promise for treating people with inflammatory bowel disease
April 17, 2019 - Daily cannabis use significantly higher among individuals with serious psychological distress
April 17, 2019 - Victims of bullying have greater chances of mental health problems, unemployment in later life
April 17, 2019 - Strategies to achieve greater vaccination coverage throughout Europe
April 17, 2019 - Online atlas created to identify, classify protein signatures present at AML diagnosis
April 17, 2019 - £1.8 million award to boost Crohn’s disease research
April 17, 2019 - Oxytocin blocks excess drinking in alcohol-dependent rats
April 17, 2019 - Rutgers researchers identify new factor essential for maintaining stem cells in the brain and gut
April 17, 2019 - Universal late pregnancy ultrasound improves health of mothers, babies and could be cost saving
April 17, 2019 - Cosmo Pharmaceuticals Announces Submission of Remimazolam NDA to FDA
April 17, 2019 - Stopping inflammation from becoming chronic
April 17, 2019 - Planned Parenthood’s ‘Risky Strategy’ To Update Its Image
April 17, 2019 - Common sleep myths may pose a significant public health threat
April 17, 2019 - Indicators of despair rising among Americans entering midlife
Weight loss after lap-band surgery alleviates arthritic knee pain

Weight loss after lap-band surgery alleviates arthritic knee pain

image_pdfDownload PDFimage_print

A new report finds that extremely obese people who have a band surgically strapped around their stomachs to restrict food intake not only lose weight but also suffer less from arthritic knee pain.

The pain, say the study leaders at NYU School of Medicine, proceeds from the deterioration and related inflammation in knee joints caused in part by the extra weight they bear. And while the pain relief seen with lap-band surgery applied to all patients with osteoarthritic knees, researchers found that it was most helpful in the youngest men and women who lost the most weight.

“Our study shows that extremely obese people seeking relief from their knee pain should consider lap-band surgery earlier because the benefits from it being successful — although significant for all ages — decrease with age,” says study senior investigator and rheumatologist Jonathan Samuels, MD.

An associate professor in the Department of Medicine at NYU School of Medicine, Samuels says it is likely that knee joints and cartilage become so damaged after a certain point that there is little cushion left for weight loss to preserve. Along these lines, the research team found that people in their 40s reported nearly twice as much pain relief after lap-band as those who had the surgery in their 50s.

More than 130,000 Americans have had the procedure done since 2011, national statistics show. Although the operation is considered relatively safe, complications may include nausea, stomach ulcers, and infection.

The study authors say their findings are especially important because one in three American adults is now overweight. Studies also show that the number of Americans with osteoarthritis has more than doubled since World War II.

Published online in the journal Seminars in Arthritis and Rheumatism in February, the new analysis was based on the experiences of 120 patients at NYU Langone Health who underwent lap-band surgery between 2002 and 2015. All were surveyed about what they remembered about their knee pain immediately before surgery, a year after their procedure, and for as long as 14 years later.

The main purpose of the survey, researchers say, was to find out why some extremely obese people showed more knee-pain relief from lap-band surgery than others. Study participants had an average body mass index, or BMI, of 40, which equates to a 5 feet and 10 inches-tall man who weighs about 280 pounds, or a 5 foot 6 inches-tall woman who weighs 250 pounds.

According to the survey results, men and women in their 40s experienced postsurgical knee pain reductions after one year of between 50 percent and 60 percent; while those in their 50s, one year later, had pain reductions between 30 percent and 40 percent; and those in their 60s, had reductions between 20 percent and 30 percent. Pain relief persisted for a decade in all patients monitored.

Results also showed that BMI at the time of surgery did not influence whose knee pain went down the most. People with BMIs in the upper 40s were just as likely to report decreased knee pain as people with BMIs in the lower 40s if they lost proportionally the same amount of total body weight.

However, study participants who lost the most weight had the steepest reductions in knee pain. Dropping more than 13 points on the BMI scale — a measure of kilograms per meter squared based on height — halved their pain scores, assessed on a scale from one to 10, when compared to people who lost eight or fewer BMI points.

Although the investigators acknowledge that surveys that gather self-reported symptoms can be biased to a certain extent, the consistency of their findings over time adds to their credibility, the NYU team noted.

Study lead investigator Shannon Chen, BA, says the team is already collecting further data on patients having lap-band and other types of more-aggressive weight-loss surgeries.

These studies are also investigating the impact of weight loss on underlying biological changes caused by fat tissue and inflammation in the knees.

Tagged with:

About author

Related Articles