Breaking News
August 18, 2018 - Blood biomarker could help predict kidney cancer up to five years prior to diagnosis
August 18, 2018 - Dartmouth scientists create more sustainable feed for aquaculture
August 18, 2018 - Immigrants Not a Burden on U.S. Health Care: Study
August 18, 2018 - Women who eat fast food take longer to become pregnant
August 18, 2018 - Most YouTube videos on plastic surgery are misleading marketing campaigns
August 18, 2018 - The essential guide to make your laboratory more sustainable
August 18, 2018 - Researchers describe promising strategy to remove melanoma’s most powerful defenses
August 18, 2018 - Women with polycystic ovary syndrome dissatisfied with medical care
August 18, 2018 - Research discoveries reveal insights behind neurological degeneration
August 18, 2018 - Researchers win multi-million Euro award to conduct research into liver disease
August 18, 2018 - Survey highlights variations in practice of airway management in pediatric intensive care units
August 18, 2018 - UK students win sponsorship from Promega Corporation
August 18, 2018 - Janssen Reports Positive Topline Results for ATLAS Phase III Study of a Novel, Long Acting Injectable Two-Drug Regimen for the treatment of HIV-1
August 18, 2018 - PSD as a molecular platform for understanding synapse formation and plasticity
August 18, 2018 - Improved visual communication could help patients to make informed health-care decisions
August 18, 2018 - New algorithm helps identify and manage diabetic patients at increased fracture risk
August 18, 2018 - Microscopic insect odour detecting mechanisms discovered
August 18, 2018 - Researchers develop new approach to study how tuberculosis infects people
August 18, 2018 - FDA Approves Kalydeco (ivacaftor) for Cystic Fibrosis in Children Ages 12 to
August 18, 2018 - An ion channel differentiates newborn and mature neurons in the adult brain
August 18, 2018 - Socio-economic position associated with pregnant women’s exposure to environmental hazards
August 18, 2018 - Voters to settle dispute over ambulance employee break times
August 18, 2018 - AGA urges policymakers and stakeholders to improve affordability of drugs
August 18, 2018 - Increasing dietary protein may lower risk of diabetes in people with NAFLD
August 18, 2018 - New HIV therapy suppresses viral replication and increases immune cells in drug-resistant patients
August 18, 2018 - Broad Genetic Testing for NSCLC May Not Improve Survival
August 18, 2018 - Discovery opens door for synthetic opioids with less addictive qualities
August 18, 2018 - Transgenic rice plant extracts could help stop the spread of HIV
August 18, 2018 - Hologic’s Cynosure division partners with Porter Instrument to distribute nitrous oxide and oxygen system
August 18, 2018 - Two thyroid medications recalled by FDA
August 18, 2018 - Forecast Sees Abnormal Heat Worldwide Through 2022
August 18, 2018 - Childhood absence epilepsy – Genetics Home Reference
August 18, 2018 - Fearing hard Brexit, UK drugmakers stockpile to protect lives
August 18, 2018 - Discovery may help broaden the scope of defenses against HPV
August 18, 2018 - When they start thinking green, they see green
August 18, 2018 - Scientists introduce microfluidics-based chip for manipulation and analysis of single cells
August 18, 2018 - Researchers design new way to grow nose cells for treating spinal cord injuries
August 18, 2018 - New light shed on relationship between calorie-burning fat and muscle function
August 18, 2018 - Surgery Saturday Instagram series takes you inside Stanford’s OR
August 18, 2018 - Researchers uncover surprising new role for inhibition in the cerebellum
August 18, 2018 - Children have better nutrition when they live near forests, global study shows
August 18, 2018 - OHSU professor conducts clinical trial with artificial pancreas using Xeris’ liquid glucagon
August 18, 2018 - HSS takes young patients with physical challenges on a surfing trip
August 18, 2018 - Study shows electronic health records leave doctors and patients unsatisfied
August 18, 2018 - Study uncovers mechanism that affects multiplication of dengue virus lineage
August 18, 2018 - UTHealth safety expert talks about preparing for the most destructive hurricanes
August 18, 2018 - Theravance Biopharma Reports Positive Top-Line Four-Week Data from Phase 2 Trial of TD-9855 for the Treatment of Symptomatic Neurogenic Orthostatic Hypotension
August 18, 2018 - Animations prove effective in accurately measuring pain
August 18, 2018 - Three faculty members appointed to endowed positions | News Center
August 18, 2018 - New technique detects, measures, analyzes unevenly charged biomolecules
August 18, 2018 - Brief exposures to stressors can be beneficial to cells, shows study
August 18, 2018 - UTHealth-led survey shows much work remains to increase safety of e-health records
August 18, 2018 - Researchers use super-resolution microscope to unravel secrets of deadly Nipah virus
August 18, 2018 - Scientists identify pathways that reveal insights into mechanism of lung cancer etiology
August 18, 2018 - Rush’s health care IT leaders reach White House
August 18, 2018 - FDA approves marketing of brainsway deep transcranial magnetic stimulation system for OCD
August 17, 2018 - OUHSC gets $20 million grant to advance research and patient care for Oklahomans
August 17, 2018 - Sperm morphology differs depending on qualities of male bird
August 17, 2018 - Texas A&M researchers develop clay-based platform to grow blood vessels
August 17, 2018 - FDA Approves Expanded Indication for Orkambi (lumacaftor/ivacaftor) in Children Ages 2-5 Years
August 17, 2018 - Caring for Concussions | NIH News in Health
August 17, 2018 - Team explores diabetes drug’s ability to treat RSV infection
August 17, 2018 - New imaging technique can spot tuberculosis infection in an hour | News Center
August 17, 2018 - PolyU researchers design new self-fitting scaffold to induce bone regeneration
August 17, 2018 - CartiHeal and LSU Health successfully enroll first two patients in Agili-C IDE pivotal study
August 17, 2018 - Less-invasive options are slowing disease progression in glaucoma patients
August 17, 2018 - Researchers discover new promising target point for cancer and diabetes therapies
August 17, 2018 - Podcast: KHN’s ‘What the Health?’ See you in court!
August 17, 2018 - New mobile phone application enables early detection of cerebral ictus
August 17, 2018 - AJMC addresses role of community pharmacies in boosting adult vaccination rates
August 17, 2018 - UK’s leading sight loss charity invites applications from brightest minds in ophthalmic research
August 17, 2018 - Alternative devices can help when autoinjectors are unavailable
August 17, 2018 - Researchers produce artificial placenta model that closely resembles natural organ
August 17, 2018 - Study offers possibility of squelching a focal epilepsy seizure before symptoms appear
August 17, 2018 - FDA Alert: Temporary Total Artificial Heart Companion 2 Driver System by SynCardia Systems: Letter to Health Care Providers
August 17, 2018 - New statewide program in North Dakota aims to stem opioid misuse
August 17, 2018 - Researchers discover why sepsis from a staph infection causes organ failure
August 17, 2018 - Stony Brook University’s new medical students start a transformative journey
August 17, 2018 - Revealed: The molecular mechanism underlying hypertrophic cardiomyopathy | News Center
August 17, 2018 - New modeling studies highlight urgent need for effective drug policy reforms to prevent HIV
Listening to music enhances effect of anti-hypertensive drugs

Listening to music enhances effect of anti-hypertensive drugs

image_pdfDownload PDFimage_print

In addition to remembering to take the medication prescribed by their cardiologists at the right times and going to the trouble of making healthy lifestyle changes, patients with high blood pressure (hypertension) can include a pleasing beneficial activity in routine treatment of the disease thanks to the discovery that listening to music significantly enhances the effect of anti-hypertensive drugs.

According to a study conducted by researchers on the Marília campus of São Paulo State University (UNESP) in Brazil, in collaboration with colleagues at Juazeiro do Norte College (FJN) and ABC Medical School (FMABC), also in Brazil, and Oxford Brookes University in the UK, music intensifies the beneficial effects of medication a short time after it is taken to control high blood pressure.

The results of the study, which was part of a project supported by the São Paulo Research Foundaiton – FAPESP, were published in Scientific Reports.

“We observed that music improved heart rate and enhanced the effect of anti-hypertensives for about an hour after they were administered,” said Vitor Engrácia Valenti, a professor in the Speech Language Pathology Department of UNESP Marília’s School of Philosophy & Sciences (FFC) and coordinator of the study.

A few years ago, the researchers at UNESP Marília began studying the effects of music on the heart in conditions of stress. One of their findings is that classical music tends to lower heart rate.

“We’ve observed classical music activating the parasympathetic nervous system and reducing sympathetic activity,” said the principal investigator of the FAPESP-funded project. The sympathetic and parasympathetic nervous systems constitute the autonomic nervous system, which maintains homeostasis. The sympathetic nervous system accelerates heart rate, constricts blood vessels and raises blood pressure. The parasympathetic nervous system controls the body at rest, slowing the heart, lowering blood pressure, and stabilizing blood sugar and adrenaline.

The researchers followed up this finding by measuring the effect of musical stimulation on heart rate variability in ordinary situations such as treatment for high blood pressure, in which music therapy has been studied as a complementary intervention.

“Previous research showed music therapy having a significant positive effect on blood pressure in hypertensive patients,” Valenti said. “But it wasn’t clear if music could influence the effects of medication on heart rate variability and on systolic and diastolic blood pressure.”

Synergy

The researchers performed an experiment to measure the effects of musical auditory stimulus associated with anti-hypertensive medication on heart rate and blood pressure in 37 patients with well-controlled hypertension. The subjects had been undergoing anti-hypertensive treatment for between six months and a year. Measurements were taken on two random days with a gap of 48 hours.

On one day, after taking their usual oral anti-hypertensive medication, patients listened to instrumental music via earphones for 60 minutes at the same volume. As control, on the other day, they underwent the same research protocol, but the earphones were not turned on.

Heart rate variability was measured at rest and at 20, 40 and 60 minutes after oral medication. Several statistical and mathematical techniques were used to detect differences between heart rates at different times, with high precision and sensitivity.

Analysis of the data showed heart rate diminishing significantly 60 minutes after medication when patients listed to music in the period. Heart rate did not fall as significantly when they did not listen to music.

Blood pressure also responded more strongly to medication when they listened to music.

“We found that the effect of anti-hypertension medication on heart rate was enhanced by listening to music,” Valenti said.

One of the hypotheses raised by the researchers is that music stimulates the parasympathetic nervous system, increases gastrointestinal activity and accelerates absorption of anti-hypertensive medication, intensifying its effects on heart rate.​

Source:

http://agencia.fapesp.br/music_intensifies_effects_of_antihypertensive_medication/27588/

Tagged with:

About author

Related Articles