Breaking News
October 19, 2018 - For-profit nursing home residents more likely to experience health issues caused by substandard care
October 19, 2018 - Conceptual framework proposed to examine role of exercise in multiple sclerosis
October 19, 2018 - Near infrared spectroscopy technique for accurate evaluation of chondral injuries
October 19, 2018 - Shorter physician encounters associated with antibiotic prescribing
October 19, 2018 - In the Spotlight: Enjoying research and exploring opportunities
October 19, 2018 - Physical activity lowers cardiovascular mortality risk in frail older adults
October 19, 2018 - New imaging tool helps visualize how sound-induced vibrations travel through the ear
October 19, 2018 - Key insights into the application, production of bioactive materials
October 19, 2018 - New urea sorbent could speed up the development of wearable artificial kidney
October 19, 2018 - Intensive care patients’ muscles less able to use fats for energy
October 19, 2018 - FDA Advisory Committee Recommends Approval of Dsuvia for the Treatment of Moderate-to-Severe Acute Pain
October 19, 2018 - 48,XXXY syndrome – Genetics Home Reference
October 19, 2018 - Physical exercise improves the elimination of toxic proteins from muscles
October 19, 2018 - How a new system improved wait times for Stanford kidney transplant patients
October 19, 2018 - Nutrition has bigger positive impact on bone mass and strength than exercise
October 19, 2018 - Study finds lack of progress in media representation of nurses over last 20 years
October 19, 2018 - Many people have trouble understanding differences between OCD and OCPD
October 19, 2018 - New family planning app found to be as effective as modern methods
October 19, 2018 - Gastric Banding, Metformin Similar for Improving Glycemia
October 19, 2018 - Physiologist publishes findings on the role of the protein titin in muscle contraction
October 19, 2018 - What digital health companies need to do to succeed
October 19, 2018 - N. Carolina Sees Alarming Spike in Heart Infections Among Opioid Users
October 19, 2018 - Video monitoring of TB therapy works well in urban and rural areas
October 19, 2018 - Determining acid-neutralizing capacity for OTC antacids
October 19, 2018 - Males who spend more time taking care of kids have greater reproductive success
October 18, 2018 - Study to explore bioethics of brain organoids
October 18, 2018 - Environmental conditions may drive development of multiple sclerosis
October 18, 2018 - Genetically modifying zebrafish provides more accurate disease models
October 18, 2018 - Purdue Pharma, Eisai announce positive topline results from Phase 3 study of lemborexant
October 18, 2018 - 5 Strength-Training Mistakes to Avoid
October 18, 2018 - Immune system’s balancing act keeps bowel disease in check
October 18, 2018 - Anti-inflammatory drug effective for treating lymphedema symptoms | News Center
October 18, 2018 - Keeping Your Voice Young
October 18, 2018 - One-time universal screening recommended to tackle increase in hepatitis C
October 18, 2018 - Researchers to develop new stem cell-based strategies for treating vision disorders
October 18, 2018 - Detecting epigenetic signature may help people stay ahead of inflammatory bowel disease
October 18, 2018 - Understanding AFib: Slowing down the dancing heart
October 18, 2018 - Using NMR to Reduce Fraud
October 18, 2018 - New automated model identifies dense breast tissue in mammograms
October 18, 2018 - Mysterious polio-like illness baffles medical experts while frightening parents
October 18, 2018 - Cases of Acute Flaccid Myelitis on the rise across U.S.
October 18, 2018 - Dietary fiber reduces brain inflammation during aging
October 18, 2018 - New tool could help prioritize recovery efforts for the poorest hit by natural disasters
October 18, 2018 - Hundreds of dietary supplements shown to contain unapproved drugs
October 18, 2018 - Active Pharmaceuticals ID’d in >700 Dietary Supplements
October 18, 2018 - Cell death protein also damps inflammation
October 18, 2018 - AI pathology diagnostic tool developed using deep learning technology from Olympus
October 18, 2018 - Health Highlights: Oct. 15, 2018
October 18, 2018 - Largest study of ‘post-treatment controllers’ reveals clues about HIV remission
October 18, 2018 - Bad Blood in Silicon Valley: A conversation with John Carreyrou
October 18, 2018 - ANTRUK’s Annual Lecture sends out message on shortage of funds for antibiotic research
October 18, 2018 - NAM special publication outlines steps to ensure interoperability of health care systems
October 18, 2018 - Novel method uses just a drop of blood to monitor effect of lung cancer therapy
October 18, 2018 - New blood test could spare cancer patients from unnecessary chemotherapy
October 18, 2018 - Training young researchers to work with data volumes arising in the health sector
October 18, 2018 - New Metrohm IC method is reliable and convenient to use for zinc oxide assay
October 18, 2018 - Global AIDS, TB fight needs more money: health fund
October 18, 2018 - Understanding the forces that cause sports concussions
October 18, 2018 - Research points to new target for treating periodontitis
October 18, 2018 - New tool improves assessment of postpartum depression symptoms
October 18, 2018 - From Biopsy to Diagnosis
October 18, 2018 - Sexual harassment and assault linked to worse physical/mental health among midlife women
October 18, 2018 - Stumped by medical school? A Q&A with a learning specialist
October 18, 2018 - Report predicts life expectancy in 2040, Spain comes out on top
October 18, 2018 - Self-lubricating condoms may help raise condom usage
October 18, 2018 - Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation
October 18, 2018 - Study finds changes in antiepileptic drug metabolism during different trimesters of pregnancy
October 18, 2018 - Autonomic nervous system directly controls stem cell proliferation, study shows
October 18, 2018 - FDA Approves Talzenna (talazoparib) for gBRCAm HER2-Negative Locally Advanced or Metastatic Breast Cancer
October 18, 2018 - Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer
October 18, 2018 - Many U.S. adults confused about primary care, study shows
October 18, 2018 - UC researcher focuses on light-mediated therapies to target breast cancer
October 18, 2018 - With philanthropic gifts, Stanford poised to make major advances in neurosciences | News Center
October 18, 2018 - Mice study shows antibiotics are not always necessary to cure sepsis
October 18, 2018 - Researchers discover why heart contractions are weaker in individuals with HCM
October 18, 2018 - Participation in organized sport during childhood may have long-term skeletal benefits
October 18, 2018 - Probiotic/antibiotic combination could eradicate drug-resistant bacteria
October 17, 2018 - More Socioeconomic Challenges for Hispanic Women With HIV
October 17, 2018 - 49,XXXXY syndrome – Genetics Home Reference
October 17, 2018 - Scientists uncover possible new causes of Tourette syndrome
ACL tears occur the same way in women and men, study finds

ACL tears occur the same way in women and men, study finds

image_pdfDownload PDFimage_print

While women are two to four times more likely than men to tear the anterior cruciate ligament (ACL) in their knee, the cause of this injury is no different between the sexes, according to new research from Duke Health.

The findings counter a common explanation for the higher incidence of the injury in women. Previous research had suggested women are more susceptible to ACL tears because their knees move differently, but the Duke team found ACL tears occur the same way in women and men.

Led by biomedical engineer Louis DeFrate, Ph.D., the Duke team used a forensic approach to reconstruct injuries by examining bone bruises on the knees of 15 men and 15 women with torn ACLs. Their findings will be published online April 18 in The American Journal of Sports Medicine.

The study, while small, is a more rigorous forensic analysis than patient interviews and slow-motion replays of athletes’ ACL tears, which other studies have relied upon to understand the injury and possible causes for the disparity between the sexes. Some experts have also attempted to create injury prevention programs targeted at women using video replays as a template.

“Based on watching videos of athlete injuries, previous researchers have suggested that females may have a different mechanism of injury than males,” DeFrate said. “But it’s difficult to determine the precise position of the knee and the time of injury through footage.”

“We used MRI scans taken within a month of the ACL rupture and identified bruises on the surface of the two large bones that collide when the ACL tears — the femur and the tibia — then used 3-D modeling and computer algorithms to reconstruct the position of the knee when the injury occurred,” he said. “Our results suggest that males and females have the same position of injury.”

Because an ACL tear is such a devastating and often career-ending injury for athletes, sports programs have made considerable efforts to devise strategies for athletes to protect the ACL with strengthening and proper landing techniques, but rates of ACL injury remain high.

Beyond the acute injury, a torn ACL also increases a person’s chances of developing osteoarthritis at an early age, setting them up for one or more knee replacements in a lifetime.

Using advanced imaging and modeling technology, DeFrate’s lab has been behind a number of important insights about ACL injury over the past 10 years.

Scientists have long held that an inward buckling motion of the knee known as valgus collapse caused the ligament to tear.

However, using their forensic biomechanics approach, DeFrate’s lab concluded in a 2015 publication that landing on a hyperextended knee is actually what tears the ACL. The awkward buckling motion — that gruesome and unnatural angle the knee takes just before the pain registers on the athlete’s face — is not the motion that tears the ligament, but occurs just afterward.

“In order to develop improved treatment strategies and prevention, we need a clear understanding of what motions are most dangerous for athletes,” he said. “This work provides new evidence that landing on an extended knee may be a dangerous position for ACL tears in both males and females.”

DeFrate’s team have also led a series of studies beginning in 2008 that found the most common technique orthopedic surgeons use to reconstruct the ACL often leads them to attach the graft in the wrong spot.

“This is like driving a car with the tires out of alignment,” DeFrate said. “This causes more severe wear on the cartilage and speeds up the process to osteoarthritis.”

His research caused controversy among orthopedic surgeons who had used the technique for decades, and he met resistance at academic meetings while presenting his work. But the findings earned him the 2016 Kappa Delta Young Investigator Award from the American Academy of Orthopedic Surgeons, the highest honor given for orthopedic research. He has worked closely with Duke Health orthopedic surgeons, including study co-author William E. Garrett, to review and refine surgical techniques.

DeFrate is hopeful that continued study of ACL injuries will lead to improvements in treatment and informed training on how to prevent the devastating injuries, especially in those at highest risk.

Source:

https://corporate.dukehealth.org/news-listing/study-shows-men-and-women-tear-acl-same-way-non-contact-injury?h=nl

Tagged with:

About author

Related Articles