Breaking News
October 23, 2018 - FDA targets 465 websites that sell potentially dangerous, unapproved drugs
October 23, 2018 - New approach may lead to better diagnostic techniques for autoimmune disorders
October 23, 2018 - Innovative computer software sheds new light on genetic processes underlying deadly diseases
October 23, 2018 - Juul Drawing Lots of Teen Followers on Twitter
October 23, 2018 - WHO says Zika risk low in Pacific ahead of Meghan visit
October 23, 2018 - A deeper look at ‘Reflecting Frankenstein’
October 23, 2018 - Breastfeeding can have protective affect against high blood pressure in women, confirms study
October 23, 2018 - Epigenetic modifications may contribute to Alzheimer’s Disease
October 23, 2018 - Volunteering for peer counseling programs benefits people with lupus
October 23, 2018 - Cancer treatment may undergo a paradigm shift to immunotherapy soon
October 23, 2018 - Study uncovers new mechanism of action in a first-line drug for diabetes
October 23, 2018 - New type of molecule shows early promise against treatment-resistant prostate cancer
October 23, 2018 - Lancet publishes pioneering study of Aimovig’s efficacy in episodic migraine patients
October 23, 2018 - Scientists grow functioning human neural networks in 3D from stem cells
October 23, 2018 - Using mushrooms as a prebiotic may help improve glucose regulation
October 23, 2018 - New ENT clinic treats children in Zimbabwe
October 23, 2018 - CUIMC Celebrates 2018-2019, Issue 2
October 23, 2018 - Immunotherapy is better than chemotherapy as first-line treatment for advanced head and neck cancer
October 23, 2018 - Polyganics begins first-in-human clinical trial of LIQOSEAL for reducing CSF leakage
October 23, 2018 - Gut bacterial community of healthy adults recovers after short-term exposure to broad-spectrum antibiotics
October 23, 2018 - Lowering systolic blood pressure does not damage the kidneys, shows study
October 23, 2018 - Incyte Announces Positive Data from Phase 2b Trial of Ruxolitinib Cream in Patients with Atopic Dermatitis
October 23, 2018 - Cardiovascular admissions more common among most deprived
October 23, 2018 - Targeted drug and hormone therapy combination extends breast cancer survival
October 23, 2018 - Map of human liver cells reveals molecular make-up of individual cells
October 23, 2018 - Drugs approved for breast cancer treatment are effective and well tolerated in men
October 23, 2018 - EKF introduces new hand-held lactate analyzer for rapid sports performance monitoring
October 23, 2018 - Researchers identify common genetic connection in lung conditions
October 23, 2018 - Forbius initiates Phase 2a trial evaluating efficacy, safety of AVID100 in patients with squamous NSCLC
October 23, 2018 - Immunotherapy achieves major pathological response in early-stage mismatch repair deficient colon cancer
October 23, 2018 - New discovery may lead to better treatment options for pancreatic cancer patients
October 23, 2018 - FDA Approves Dupixent (dupilumab) for Moderate-to-Severe Asthma
October 23, 2018 - Researchers identify immune culprits linked to inflammation and bone loss in gum disease
October 23, 2018 - Despite lower risk factors, black men have higher rates of recidivism
October 23, 2018 - Study finds why pregnant women in mainland China, Hong Kong and Taiwan prefer cesarean delivery
October 23, 2018 - AbbVie’s U-ACHIEVE Phase 2b/3 dose-ranging study improves outcomes in patients with ulcerative colitis
October 23, 2018 - NCI grant awarded to Abramson Cancer Center to study CAR T cells In solid tumors
October 23, 2018 - Scientists use electron microscope to study chemical transformation in catalytic cross-coupling reaction
October 23, 2018 - Research offers new hope to men who received childhood cancer treatment
October 23, 2018 - New medical navigation system receives international innovation award
October 23, 2018 - Adverse Childhood Experiences Tied to Burnout in BSN Students
October 23, 2018 - High levels of oral disease among elite athletes affecting performance
October 23, 2018 - Study examines effect of immediate vs delayed pushing during labor on delivery outcomes
October 23, 2018 - LU-RRTC to spearhead capacity-building efforts for racial and ethnic populations
October 23, 2018 - Maintenance therapy with olaparib improves progression-free survival in advanced ovarian cancer patients
October 23, 2018 - Organic food may protect against cancers finds study
October 23, 2018 - Interweaving anxiety disorder associated with stuttering remains unrecognized
October 23, 2018 - Cannabis oil shown to significantly improve Crohn’s disease symptoms
October 23, 2018 - Knowledge of sex differences in lower urinary tract may help stimulate breakthroughs in diagnosis, management
October 23, 2018 - Common antibodies associated with myocardial infarction
October 23, 2018 - Study reveals new treatment option for women with advanced breast cancer resistant to hormone therapy
October 23, 2018 - Brain’s ‘Self-Control’ Center May Be Key to Weight-Loss Success
October 23, 2018 - Prosthetic valve mismatches common in transcatheter valve replacement, ups risk of death
October 23, 2018 - Can virtual reality help people become more compassionate?
October 23, 2018 - Screen time eclipsed outdoor time for most students, shows study
October 23, 2018 - SLU researcher seeks to find solutions for ‘chemo brain’ symptoms and side effects of opioids
October 23, 2018 - Plastics now commonly found in human stools
October 23, 2018 - Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer
October 23, 2018 - Cancer survivors at risk for heart failure during, after pregnancy
October 23, 2018 - Stanford project brings health education videos to mothers in South Africa
October 23, 2018 - HIV-infected Hispanics at higher risk of developing HPV-related cancers, finds study
October 23, 2018 - Politicians hop aboard ‘Medicare-for-all’ train, destination unknown
October 23, 2018 - Study suggests rising childhood obesity rates as cause for serious hip disease in adolescents
October 23, 2018 - Study highlights existence of barriers to early clinical trial access for adolescents and young adults
October 23, 2018 - Protein sequencing technique could revolutionize biomedical research
October 23, 2018 - Canon Medical to showcase world’s first Ultra-High Resolution CT system at ASTRO 2018
October 23, 2018 - Spectrum Pharmaceuticals Announces Release of Updated Poziotinib Data From MD Anderson Phase 2 Study in Non-Small Cell Lung Cancer Patients
October 23, 2018 - Cancer stem cells use ‘normal’ genes in abnormal ways
October 23, 2018 - Bad Blood: A conversation with investigative reporter John Carreyrou | News Center
October 23, 2018 - As U.S. fertility rates collapse, finger-pointing and blame follow
October 23, 2018 - Researchers develop promising targeted strategy to treat chemo-resistant blood cancer
October 23, 2018 - Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus
October 23, 2018 - Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer
October 23, 2018 - 11th World Stroke Congress examines high stroke impact in low- and middle-income countries
October 22, 2018 - Breast cancer survival could be extended with two new drug combinations
October 22, 2018 - Researchers discover how acne-causing bacteria resist treatment
October 22, 2018 - Cancer trial shows treating the prostate with radiotherapy improves survival
October 22, 2018 - New hope for a drug to treat lymphedema symptoms
October 22, 2018 - Immune-Based Treatment Helps Fight Aggressive Breast Cancer, Study Finds
October 22, 2018 - Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC
Deep-frozen juices defrosted to room temperature can increase carotenoids level in body

Deep-frozen juices defrosted to room temperature can increase carotenoids level in body

image_pdfDownload PDFimage_print

Researchers from the Laboratory of Food Color and Quality at the University of Seville have published a study in which it is shown how certain types of cold treatment that are used by the citrus fruits industry in the preparation of juices have a great impact on the color of orange juice and on the concentration and bioaccessibility of the carotenoids present in the juice.

The bioaccessibility of a compound is the quantity of that compound that is freed from the food and is capable of being absorbed by the intestinal wall so that it arrives in the blood and is accumulated in the different organs/tissues where they can effect their potential health benefits.

The cold treatments have two opposite effects. On one hand, they cause the carotenoids to degrade (negative effect) and, on the other hand, they generate an increase in the bioaccessibility of the carotenoids (positive effect). Taking these two effects into account, it can be concluded that deep-frozen juices that are defrosted to room temperature or in a microwave are potentially better at increasing the level of carotenoids in the body.

During this project, testing was done on fresh orange juice, on deep-frozen juice that had been defrosted to room temperature, either in a microwave or in the fridge, and on pasteurized juices. The analysis focused on two carotenoids in particular, phytoene and phytofluene, which are both colorless. “These compounds are increasingly acquiring importance among the scientific community as there are ever more studies that indicate their various benefits for health and cosmetics”, explains the University of Seville teacher Paula Mapelli.

Although all the cold treatments analyzed generated carotenoid loss, the deep-frozen juices that were defrosted to room temperature or in a microwave were better sources of bioaccessible carotenoids than fresh juice. “That is to say, despite the fact that the concentration of carotenoids in the deep-frozen juices was less than in the fresh juice, the reduction in the size of the particles and the destruction of the cellular material that these treatment produce mean that the amount of carotenoids that can be absorbed by the intestine is higher”, the researcher adds.

According to the results, among the treatments analyzed, pasteurization is the treatment that produces the highest level of carotenoid degradation and the greatest change in the color of the juice.

To the question as to in which conditions the natural properties of the juice are best preserves, the experts respond that “fresh juice is the juice that has the highest concentration of carotenoids, but this does not mean that it is the one that raises the carotenoid level in the blood and tissue the most, as you have to take into account the amount of carotenoids that are actually absorbed”.

“Consumers tend to think that treated juices are “less healthy” than fresh juices. However, in this study, it has been shown how, at least in relation to the content of carotenoids that reaches the blood and tissue to protect us from disease, this is not always correct”, comments the University of Seville Faculty of Pharmacy teacher Antonio J. Meléndez.

Pinalate Orange and the CITIUS laboratories
This research was carried out using the Pinalate variety of orange. This variety is a spontaneous mutation of the Navelate sweet orange. It is totally “natural”, not transgenic. The most important characteristic of this variety is that it has a high concentration of the colorless carotenoids phytoene and phytofluene.

To carry out the project, use was made of the services of Microscopy, Functional Characterization and Biology situated on the Centers of Research, Technology and Innovation at the University of Seville (CITIUS). In addition, it benefitted from the collaboration of the doctors María Jesús Rodrigo and Lorenzo Zacarías of the Department of Food Biotechnology, Institute of Agricultural Chemistry and Food Technology (IATA-CSIC) in Valencia. The study was possible thanks to funding from the Council of Innovation, Science and Business (Consejería de Innovación, Ciencia y Empresas) of The Andalusian Regional Government (project CAROTINCO-P12-AGR-1287) and from the Ministry of Economy and Competiveness (network of excellence BIO2015-71703-REDT).

“Our next step, which will complete this research, will be to determine the content of colorless carotenoids in the blood after consuming these and other orange juices. That is to say, an in vivo study that corroborates this and other previous in vitro studies with other orange juices”, states the researcher Carla María Stinco, also author of the study.

Tagged with:

About author

Related Articles