Breaking News
November 12, 2018 - Cocaine Cut With Anti-Worming Drug, Levamisole, May Cause Brain Damage
November 12, 2018 - Obese mice lose a third of their fat using a natural protein
November 12, 2018 - Behind many a Parkinson’s case lurks a mutation in a gene called LRRK2 — why?
November 12, 2018 - Drug with fish oil cuts risk of heart attack, stroke, study finds
November 12, 2018 - Mild exposure to single blast can induce meaningful pathogenic effects, study shows
November 12, 2018 - Miniature pacemakers aim to make heart procedures for infants less invasive, more efficient
November 12, 2018 - Treating pre-cancerous stem cells at early stage could be key to preventing bowel cancer
November 12, 2018 - Kawasaki disease triggered by a combination of factors
November 12, 2018 - Optibrium and University of Nottingham Collaborate on Innovative Teaching Programme
November 12, 2018 - RNA defects linked to multiple myeloma progression in high risk patients
November 12, 2018 - Science is on trial – and we need doctors to provide the defense
November 12, 2018 - Salk researchers receive $19.2 million to unravel mysteries of age-related cognitive decline
November 12, 2018 - KE Eye Centers offer new solution for patients with myopia and astigmatism
November 12, 2018 - Trumpeted new Medicare Advantage benefits will be hard for seniors to find
November 12, 2018 - Biogen and Eisai Announce Presentation of Detailed Analyses from the Phase 1b Long-Term Extension Study of Aducanumab at Clinical Trials on Alzheimer’s Disease (CTAD)
November 12, 2018 - Scientists reveal new cystic fibrosis treatments work best in inflamed airways
November 12, 2018 - Inexpensive and effective drug does not reduce major adverse cardiovascular event rates
November 12, 2018 - Testing coronary calcium levels can better predict patient’s risk for coronary heart disease
November 12, 2018 - FDA conducts mass seizure of food and medical products held under insanitary conditions
November 12, 2018 - FDA Approves Invokana (canagliflozin) to Reduce the Risk of Heart Attack, Stroke or Cardiovascular Death in Adults with Type 2 Diabetes and Established Cardiovascular Disease
November 12, 2018 - Hormone helps reverse brain damage caused by obesity
November 12, 2018 - Grants aim to provide better cancer clinical trial access for military veterans
November 12, 2018 - Mitochondrial DNA may have strong influence on cellular metabolism and disease susceptibility
November 12, 2018 - High stakes, entrenched interests and the Trump rollback of environmental regs
November 12, 2018 - Stem cells transplanted for treatment of Parkinson’s disease
November 12, 2018 - Sandoz Inc. Issues Voluntary Nationwide Recall of One Lot of Losartan Potassium and Hydrochlorothiazide Due to the Detection of Trace Amounts of NDEA (N-Nitrosodiethylamine) Impurity Found in the Active Pharmaceutical Ingredient (API)
November 12, 2018 - Protein found in patients with severe asthma can help identify who would benefit from targeted drugs
November 12, 2018 - Experts develop a list of competencies in antimicrobial prescribing and stewardship
November 12, 2018 - Allied BioScience receives approved label from EPA for new bacteriostatic surface coating
November 12, 2018 - MR Solutions displays elegant bench top CT scanner with clip-on PET and SPECT at EANM congress
November 12, 2018 - FDA announces emergency use authorization of Ebola fingerstick test with portable reader
November 12, 2018 - Grieving spouses with sleep problems have increased risk of chronic immune activation
November 12, 2018 - Exercise routines affect mental health in Japanese expatriates
November 12, 2018 - Fish oil and vitamin D pills no guard against cancer or serious heart trouble
November 12, 2018 - Excess Gestational Weight Gain Not Better for Child Bone Health
November 12, 2018 - Immune receptor provides protective immunity against Group A Streptococcus
November 12, 2018 - Scientists develop new method to produce irradiated nanomaterials for medical applications
November 12, 2018 - Blue light exposure decreases blood pressure
November 12, 2018 - Researchers discover two proteins essential for development of skeletal muscle
November 12, 2018 - Yelp reviews help understand strengths, weaknesses of emergency departments and urgent care centers
November 12, 2018 - Adolescent obesity linked with increased risk of pancreatic cancer later in life
November 12, 2018 - AHA: Poor Teeth-Brushing Habits Tied to Higher Heart Risk
November 12, 2018 - Researchers find how natural killer cells regulate protective HIV antibodies
November 12, 2018 - Rutgers receives $4.2 million federal grant to improve mental health services
November 12, 2018 - Sussex scientists develop a piece of hardware to show how brains function
November 12, 2018 - Study shows pivotal role of parents in efforts to change sexual orientation of LGBT teens
November 12, 2018 - Neck scan detects dementia way before symptoms appear
November 12, 2018 - Risk-profiling can benefit HIV prevention
November 12, 2018 - New thrombolytic based on magnetite nanoparticles successfully tested on animals
November 12, 2018 - Smoking rates go down in the US, lowest since 1965
November 12, 2018 - Phase III Trial of Darolutamide in Patients with Non-metastatic Castration-resistant Prostate Cancer Meets Primary Endpoint
November 12, 2018 - Moderate exercise before conception resulted in lower body weight, increased insulin sensitivity of offspring
November 11, 2018 - Community choirs for older adults reduce loneliness and increase interest in life
November 11, 2018 - Trevena Receives Complete Response Letter for Oliceridine from FDA
November 11, 2018 - More adults and children are using yoga and meditation
November 11, 2018 - Female smokers at greater risk of heart attacks, finds study
November 11, 2018 - Happy Childhood Memories Associated With Better Health
November 11, 2018 - X-linked infantile spinal muscular atrophy – Genetics Home Reference
November 11, 2018 - RNA thought to spread cancer shows ability to suppress breast cancer metastasis
November 11, 2018 - Study finds that thymus plays key role during normal pregnancy
November 11, 2018 - Exploring why some athletes ice their muscles after exercise
November 11, 2018 - Female Genital Mutilation Decreasing in African Nations
November 11, 2018 - Are humans immune to the CRISPR-Cas9 gene editing scissors?
November 11, 2018 - Breastmilk and saliva mixtures regulate oral microbiome of newborn babies
November 11, 2018 - Learning familiar faces through social interactions reduces variability in face recognition
November 11, 2018 - New open source decision support tool could help clinicians chose chemotherapy drugs
November 11, 2018 - New weapons drawn in global TB fight
November 11, 2018 - UCB and Biogen Announce Topline Results from a Phase 2b Study of Dapirolizumab Pegol in Systemic Lupus Erythematosus
November 11, 2018 - Surgery restores boy’s ability to walk post-acute flaccid myelitis
November 11, 2018 - Comorbidity negatively impacts quality of life in people with dementia
November 11, 2018 - Neuroscientists receive $16.75 million from BRAIN Initiative to decipher the brain’s visual system
November 11, 2018 - Purdue researchers invent new smart drainage device to help glaucoma patients
November 11, 2018 - New initiative may benefit entrepreneurs working to transform patient care
November 11, 2018 - Sage Therapeutics Announces FDA Advisory Committee Votes 17-1 in Support of Benefit-Risk Profile of Zulresso (brexanolone) Injection for Treatment of Postpartum Depression
November 11, 2018 - Exercise could delay progression of type 1 diabetes when first diagnosed
November 11, 2018 - Study of gaze fixation in monkeys reveals role of dopamine neurons in response inhibition
November 11, 2018 - Bilingual therapy is vital to improve language disorders in dual-language children, finds study
November 11, 2018 - More Frequent Surveillance No Benefit After NSCLC Resection
November 11, 2018 - Phenylketonuria (PKU) Screening: MedlinePlus Lab Test Information
November 11, 2018 - Researchers discovered a new mechanism of action in a first-line drug for diabetes
ANA (Antinuclear Antibody) Test: MedlinePlus Lab Test Information

ANA (Antinuclear Antibody) Test: MedlinePlus Lab Test Information

image_pdfDownload PDFimage_print

What is an ANA (Antinuclear Antibody) Test?

An ANA test looks for antinuclear antibodies in your blood. If the test finds antinuclear antibodies in your blood, it may mean you have an autoimmune disorder. An autoimmune disorder causes your immune system to attack your own cells, tissues, and/or organs by mistake. These disorders can cause serious health problems.

Antibodies are proteins that your immune system makes to fight foreign substances like viruses and bacteria. But an antinuclear antibody attacks your own healthy cells instead. It’s called “antinuclear” because it targets the nucleus (center) of the cells.

Other names: antinuclear antibody panel, fluorescent antinuclear antibody, FANA, ANA

What is it used for?

An ANA test is used to help diagnose autoimmune disorders, including:

  • Systemic lupus erythematosus (SLE). This is the most common type of lupus, a chronic disease affecting multiple parts of the body, including the joints, blood vessels, kidneys, and brain.
  • Rheumatoid arthritis, a condition that causes pain and swelling of the joints, mostly in the hands and feet
  • Scleroderma, a rare disease affecting the skin, joints, and blood vessels
  • Sjogren’s syndrome, a rare disease affecting the body’s moisture-making glands

Why do I need an ANA test?

Your health care provider may order an ANA test if you have symptoms of lupus or another autoimmune disorder. These symptoms include:

What happens during an ANA test?

A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Will I need to do anything to prepare for the test?

You don’t need any special preparations for an ANA test.

Are there any risks to the test?

There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.

What do the results mean?

A positive result on an ANA test means that antinuclear antibodies were found in your blood. You may get a positive result if:

  • You have SLE (lupus).
  • You have a different type of autoimmune disease.
  • You have a viral infection.

A positive result doesn’t necessarily mean you have a disease. Some healthy people have antinuclear antibodies in their blood. In addition, certain medicines can affect your results.

If your ANA test results are positive, your health care provider will likely order more tests, especially if you have symptoms of disease. If you have questions about your results, talk to your health care provider.

Is there anything else I need to know about an ANA test?

Antinuclear antibody levels tend to increase with age. As many as one-third of healthy adults over the age of 65 may have a positive ANA test result.

References

  1. American College of Rheumatology [Internet]. Atlanta: American College of Rheumatology; c2017. Antinuclear Antibodies (ANA) [updated 2017 Mar; cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Antinuclear-Antibodies-ANA
  2. Hinkle J, Cheever K. Brunner & Suddarth’s Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Antinuclear Antibodies (ANAS); 53 p.
  3. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2018. Antinuclear Antibody (ANA); [updated 2018 Feb 1; cited 2018 Feb 8]; [about 2 screens]. Available from: https://labtestsonline.org/understanding/analytes/ana/tab/test
  4. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2018. Scleroderma; [updated 2017 Sep 20; cited 2018 Feb 8]; [about 2 screens]. Available from: https://labtestsonline.org/understanding/conditions/scleroderma
  5. Lupus Research Alliance [Internet]. New York: Lupus Research Alliance; c2017. About Lupus [cited 2017 Nov 17]; [about 2 screens]. Available from: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/about-lupus
  6. Lupus Research Alliance [Internet]. New York: Lupus Research Alliance; c2017. Symptoms [cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/symptoms
  7. Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co., Inc.; c2017. Sjögren’s Syndrome [cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/sj%C3%B6gren-syndrome
  8. Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co., Inc.; c2017. Systemic Lupus Erythematosus (SLE) [cited 2017 Nov 17]; [about 3 screens]. Available from: http://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/systemic-lupus-erythematosus-sle
  9. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2017. ANA test: Overview; 2017 Aug 3 [cited Nov 17]; [about 3 screens]. Available from: https://www.mayoclinic.org/tests-procedures/ana-test/home/ovc-20344718
  10. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2017. ANA test: Results; 2017 Aug 3 [cited Nov 17]; [about 7 screens]. Available from: https://www.mayoclinic.org/tests-procedures/ana-test/details/results/rsc-20344732
  11. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2017. ANA test: Why it’s done; 2017 Aug 3 [cited Nov 17]; [about 4 screens]. Available from: https://www.mayoclinic.org/tests-procedures/ana-test/details/why-its-done/icc-20344722
  12. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests; [cited 2018 Feb 8]; [about 3 screens]. Available from: https://www.nhlbi.nih.gov/health-topics/blood-tests
  13. NIH U.S. National Library of Medicine: Genetics Home Reference [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; rheumatoid arthritis; 2017 Nov 14 [cited 2017 Nov 17]; [about 2 screens]. Available from: https://ghr.nlm.nih.gov/condition/rheumatoid-arthritis
  14. UF Health: University of Florida Health [Internet]. University of Florida; c2017. Antinuclear antibody panel: Overview [updated 2017 Nov 17; cited 2017 Nov 17]; [about 2 screens]. Available from: https://ufhealth.org/antinuclear-antibody-panel
  15. University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2017. Health Encyclopedia: Antinuclear Antibody [cited 2017 Nov 17]; [about 2 screens]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=antinuclear_antibodies
  16. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2017. Antinuclear Antibodies (ANA): Results [updated 2016 Oct 31; cited 2017 Nov 17]; [about 8 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html#hw2323
  17. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2017. Antinuclear Antibodies (ANA): Test Overview [updated 2016 Oct 31; cited 2017 Nov 17]; [about 2 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html
  18. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2017. Antinuclear Antibodies (ANA): Why It’s Done [updated 2016 Oct 31; cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html#hw2304
Tagged with:

About author

Related Articles