Breaking News
September 21, 2018 - CHMP grants positive opinion for VENCLYXTO plus rituximab for treating relapsed/refractory CLL
September 21, 2018 - Study offers solid link between visceral organs and brain’s reward, motivation system
September 21, 2018 - First U.S. patient treated with innovative gene therapy at Bascom Palmer Eye Institute
September 21, 2018 - Choroidal Detachment – The American Society of Retina Specialists
September 21, 2018 - Discovery of a key protein involved in the development of autism
September 21, 2018 - Henry Ford Health System receives $600k grant to study genetic makeup of gliomas
September 21, 2018 - Arthritis common in individuals with varying degrees of depression, finds study
September 21, 2018 - New research suggests link between PFAS chemicals and hyperthyroidism in pet cats
September 21, 2018 - Multi-year study data shows impact of new soft contact lens to slow myopia progression in children
September 21, 2018 - Neuroscientists identify circuit for brain’s statistical inference about motion
September 21, 2018 - MILabs’ VECTor6 system wins Commercial Innovation Award at WMIC 2018
September 21, 2018 - Scientists find wild African monkeys infected with bacterium that causes syphilis, yaws in humans
September 21, 2018 - 2006 to 2015 Saw Increase in Severe Maternal Morbidity
September 21, 2018 - Similar changes in the brains of patients with ADHD and emotional instability
September 21, 2018 - Cobalt mining in DR Congo takes a high toll on both creuseurs and environment
September 21, 2018 - Eating fatty fish during pregnancy may boost unborn child’s brain development
September 21, 2018 - Study reveals promising new drug candidate to treat acute renal failure
September 21, 2018 - Neural signal that urges to eat overpowers the one that says to stop
September 21, 2018 - Scientists achieve breakthrough in accelerated diagnosis of multi-resistant hospital pathogens
September 21, 2018 - Researchers simulate how different breast tissues respond to heat from MRIs
September 21, 2018 - Despite red flags at surgery centers, overseers award gold seals
September 21, 2018 - Zapping Airway Nerves May Help COPD Patients Breathe
September 21, 2018 - Researchers find answers as to why some people are at risk of gout
September 21, 2018 - Stars of Stanford Medicine: Genetic counseling and compassion
September 21, 2018 - Researchers use reinforcement learning to train gliders to soar like birds
September 21, 2018 - New federally-funded research project could lead to treatments that extend human lifespan
September 21, 2018 - Health insurance ads have shifted over time due to health plans offered via ACA
September 21, 2018 - Use of transcranial electrical stimulation to bolster creativity has far-reaching implications
September 21, 2018 - Scientists find way to boost efficacy of powerful antimalarial drug with anti-cancer medicines
September 21, 2018 - Weighing the risks and benefits of drug tapering—two patients, two perspectives
September 21, 2018 - The “exposome” revealed: a barrage of bacteria, chemicals, microscopic animals and more
September 21, 2018 - Top three immune boosting recommendations to ward off freshers’ flu
September 21, 2018 - Young children’s oral microbiota could serve as early indicator for obesity
September 21, 2018 - Older individuals with multiple sclerosis report higher quality of life than younger counterparts
September 21, 2018 - LineaRx signs agreement with Takis/Evvivax to develop linear-DNA based anti-cancer vaccines
September 21, 2018 - AbbVie Presents Upadacitinib Longer-Term (32-Week) and Patient-Reported Outcomes Data from Phase 2b Atopic Dermatitis Study at 27th European Academy of Dermatology and Venereology (EADV) Congress
September 21, 2018 - Alzheimer’s drug may stop disease if used before symptoms develop
September 21, 2018 - Human skeletal stem cell can generate cartilage, bone
September 21, 2018 - UK and European research collaborations receive vote of confidence by three major cancer charities
September 21, 2018 - Microbiota in the intestines and cell stress cause colon cancer
September 20, 2018 - Arizona EMTs have 39% higher risk for suicide than general public
September 20, 2018 - Driving and older adults: MedlinePlus Medical Encyclopedia
September 20, 2018 - Brain region for stress control is enlarged in people with depression, finds study
September 20, 2018 - Researchers test autobiographical memory for early Alzheimer’s detection
September 20, 2018 - Organizations join forces to help teens with severe mental health challenges | News Center
September 20, 2018 - Neurons in the human brain can encode numerical information
September 20, 2018 - Potential drugs to treat neurodegenerative diseases garner $3 million grant
September 20, 2018 - Processing speed important to higher order cognitive function in multiple sclerosis patients
September 20, 2018 - Helping a patient survive a hurricane
September 20, 2018 - Tafamidis Treats Transthyretin Amyloid Cardiomyopathy
September 20, 2018 - Low academic achievement can lead to drug abuse decades later, research finds
September 20, 2018 - Study identifies stem cell that gives rise to new bone, cartilage in humans | News Center
September 20, 2018 - Celltrion and Emory University sign ‘Incubation’ agreement to develop new drug candidates for atherosclerosis
September 20, 2018 - TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal
September 20, 2018 - Could Household Cleaners Make Your Kid Fat?
September 20, 2018 - Addiction nonprofit makes searching for services simple
September 20, 2018 - We are bombarded by thousands of diverse species and chemicals | News Center
September 20, 2018 - Experts to Present Prostate Cancer Advances at Patient Summit
September 20, 2018 - Alector announces initiation of Phase 1 trial of AL001 for treating frontotemporal dementia
September 20, 2018 - Pfizer’s 20vPnC vaccine receives Breakthrough Therapy designation from FDA
September 20, 2018 - Study could allow doctors to screen patients at risk from Aspergillus
September 20, 2018 - Emergex signs MoU with Brazil’s Fiocruz for development of viral vaccines
September 20, 2018 - The ‘real you’ is a myth – we constantly create false memories to achieve the identity we want
September 20, 2018 - Researchers describe cell mechanism that optimizes proteins production in stressful situations
September 20, 2018 - Cell Medica successfully doses first patient with CMD-501 targeting pediatric neuroblastoma
September 20, 2018 - Sesen Bio to present its three-month Phase 3 VISTA Trial data at Global Congress
September 20, 2018 - Senators unveil legislation to protect patients against surprise medical bills
September 20, 2018 - Study provides insights into development of special-purpose cosmetic products
September 20, 2018 - Research shows enlarged genotype-phenotype correlation for three-base pair deletion in NF1
September 20, 2018 - 91% of people around the world believe medical research will result in dementia cure
September 20, 2018 - DePuy Synthes introduces CONCORDE LIFT Expandable Interbody Device at EUROSPINE 2018
September 20, 2018 - Manx Telecom unveils MT clearSound that improves clarity of mobile phone calls
September 20, 2018 - Mediterranean-style diet appears to reduce stroke risk in women
September 20, 2018 - AbbVie Announces Patient-Reported Outcomes Data from Three Pivotal Phase 3 Studies of Risankizumab, Showing Significant Improvements in Health-Related Quality of Life for Patients with Psoriasis
September 20, 2018 - Characterization of pregnancy microbiome reveals variations in bacterial diversity
September 20, 2018 - New guidance for treatment of bone loss in hematologic stem cell transplant Recipients
September 20, 2018 - Experts to present research on prevention, management of dysphagia at international conference
September 20, 2018 - New study focuses on two-way gene switches controlling gene activity
September 20, 2018 - Zika virus could become a weapon against brain cancer
September 20, 2018 - Home-based video game exercises can reduce chronic low back pain in older people, study finds
ANA (Antinuclear Antibody) Test: MedlinePlus Lab Test Information

ANA (Antinuclear Antibody) Test: MedlinePlus Lab Test Information

image_pdfDownload PDFimage_print

What is an ANA (Antinuclear Antibody) Test?

An ANA test looks for antinuclear antibodies in your blood. If the test finds antinuclear antibodies in your blood, it may mean you have an autoimmune disorder. An autoimmune disorder causes your immune system to attack your own cells, tissues, and/or organs by mistake. These disorders can cause serious health problems.

Antibodies are proteins that your immune system makes to fight foreign substances like viruses and bacteria. But an antinuclear antibody attacks your own healthy cells instead. It’s called “antinuclear” because it targets the nucleus (center) of the cells.

Other names: antinuclear antibody panel, fluorescent antinuclear antibody, FANA, ANA

What is it used for?

An ANA test is used to help diagnose autoimmune disorders, including:

  • Systemic lupus erythematosus (SLE). This is the most common type of lupus, a chronic disease affecting multiple parts of the body, including the joints, blood vessels, kidneys, and brain.
  • Rheumatoid arthritis, a condition that causes pain and swelling of the joints, mostly in the hands and feet
  • Scleroderma, a rare disease affecting the skin, joints, and blood vessels
  • Sjogren’s syndrome, a rare disease affecting the body’s moisture-making glands

Why do I need an ANA test?

Your health care provider may order an ANA test if you have symptoms of lupus or another autoimmune disorder. These symptoms include:

What happens during an ANA test?

A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Will I need to do anything to prepare for the test?

You don’t need any special preparations for an ANA test.

Are there any risks to the test?

There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.

What do the results mean?

A positive result on an ANA test means that antinuclear antibodies were found in your blood. You may get a positive result if:

  • You have SLE (lupus).
  • You have a different type of autoimmune disease.
  • You have a viral infection.

A positive result doesn’t necessarily mean you have a disease. Some healthy people have antinuclear antibodies in their blood. In addition, certain medicines can affect your results.

If your ANA test results are positive, your health care provider will likely order more tests, especially if you have symptoms of disease. If you have questions about your results, talk to your health care provider.

Is there anything else I need to know about an ANA test?

Antinuclear antibody levels tend to increase with age. As many as one-third of healthy adults over the age of 65 may have a positive ANA test result.

References

  1. American College of Rheumatology [Internet]. Atlanta: American College of Rheumatology; c2017. Antinuclear Antibodies (ANA) [updated 2017 Mar; cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Antinuclear-Antibodies-ANA
  2. Hinkle J, Cheever K. Brunner & Suddarth’s Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Antinuclear Antibodies (ANAS); 53 p.
  3. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2018. Antinuclear Antibody (ANA); [updated 2018 Feb 1; cited 2018 Feb 8]; [about 2 screens]. Available from: https://labtestsonline.org/understanding/analytes/ana/tab/test
  4. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2018. Scleroderma; [updated 2017 Sep 20; cited 2018 Feb 8]; [about 2 screens]. Available from: https://labtestsonline.org/understanding/conditions/scleroderma
  5. Lupus Research Alliance [Internet]. New York: Lupus Research Alliance; c2017. About Lupus [cited 2017 Nov 17]; [about 2 screens]. Available from: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/about-lupus
  6. Lupus Research Alliance [Internet]. New York: Lupus Research Alliance; c2017. Symptoms [cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.lupusresearch.org/understanding-lupus/what-is-lupus/symptoms
  7. Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co., Inc.; c2017. Sjögren’s Syndrome [cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/sj%C3%B6gren-syndrome
  8. Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co., Inc.; c2017. Systemic Lupus Erythematosus (SLE) [cited 2017 Nov 17]; [about 3 screens]. Available from: http://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/autoimmune-disorders-of-connective-tissue/systemic-lupus-erythematosus-sle
  9. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2017. ANA test: Overview; 2017 Aug 3 [cited Nov 17]; [about 3 screens]. Available from: https://www.mayoclinic.org/tests-procedures/ana-test/home/ovc-20344718
  10. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2017. ANA test: Results; 2017 Aug 3 [cited Nov 17]; [about 7 screens]. Available from: https://www.mayoclinic.org/tests-procedures/ana-test/details/results/rsc-20344732
  11. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2017. ANA test: Why it’s done; 2017 Aug 3 [cited Nov 17]; [about 4 screens]. Available from: https://www.mayoclinic.org/tests-procedures/ana-test/details/why-its-done/icc-20344722
  12. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests; [cited 2018 Feb 8]; [about 3 screens]. Available from: https://www.nhlbi.nih.gov/health-topics/blood-tests
  13. NIH U.S. National Library of Medicine: Genetics Home Reference [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; rheumatoid arthritis; 2017 Nov 14 [cited 2017 Nov 17]; [about 2 screens]. Available from: https://ghr.nlm.nih.gov/condition/rheumatoid-arthritis
  14. UF Health: University of Florida Health [Internet]. University of Florida; c2017. Antinuclear antibody panel: Overview [updated 2017 Nov 17; cited 2017 Nov 17]; [about 2 screens]. Available from: https://ufhealth.org/antinuclear-antibody-panel
  15. University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2017. Health Encyclopedia: Antinuclear Antibody [cited 2017 Nov 17]; [about 2 screens]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=antinuclear_antibodies
  16. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2017. Antinuclear Antibodies (ANA): Results [updated 2016 Oct 31; cited 2017 Nov 17]; [about 8 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html#hw2323
  17. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2017. Antinuclear Antibodies (ANA): Test Overview [updated 2016 Oct 31; cited 2017 Nov 17]; [about 2 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html
  18. UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2017. Antinuclear Antibodies (ANA): Why It’s Done [updated 2016 Oct 31; cited 2017 Nov 17]; [about 3 screens]. Available from: https://www.uwhealth.org/health/topic/medicaltest/antinuclear-antibodies/hw2297.html#hw2304
Tagged with:

About author

Related Articles