Breaking News
September 24, 2018 - A new approach for finding Alzheimer’s treatments
September 24, 2018 - USC research uncovers previously unknown genetic risk factor for dementia
September 24, 2018 - Study examining mental health among students finds significant disparities in treatment across race
September 24, 2018 - Breakthrough discovery paves way for future test to identify drowsy drivers
September 24, 2018 - Transcatheter mitral-valve repair in patients with heart failure
September 24, 2018 - Study opens new avenues for treatment of Laing distal myopathy
September 24, 2018 - Stroke Facts | cdc.gov
September 24, 2018 - Sarcolipin tricks muscle cells into using more energy, burning fat
September 24, 2018 - Enrollment in opioid controlled substance agreement reduces primary care visits
September 24, 2018 - UTA researchers patent new smart seat cushion technology that helps prevent painful ulcers
September 24, 2018 - Second HPV-Related Primary Cancers Common in Survivors
September 24, 2018 - How a virus destabilizes the genome
September 24, 2018 - Old letters provide insight into Spanish flu pandemic horror
September 23, 2018 - Smart textile-based soft robotic exosuit helps wearers save energy and traverse difficult terrain
September 23, 2018 - New research hub to drive radical change in development and manufacturing of vaccines
September 23, 2018 - AHA: For Hispanics, Neighborhood May Be Key Factor in Heart Disease Risk
September 23, 2018 - Excessive airway nerves tied to more severe asthma symptoms, study finds
September 23, 2018 - Study highlights need to remain vigilant in maintaining key infection control processes
September 23, 2018 - Novel therapeutic strategy for blood vessel related disorders, such as cancer and retinopathy
September 23, 2018 - New naturally occurring antibiotic found effective against Mycobacterium tuberculosis
September 23, 2018 - First-in-human phase 0 study shows clinically-relevant activity of new drug in glioblastoma
September 23, 2018 - Removing tobacco product display from shops reduced number of children buying cigarettes
September 23, 2018 - Random fraction of specialized immune cells leads the charge in battling invaders
September 23, 2018 - Few minutes of sprinting exercise may be as effective as longer exercise sessions
September 23, 2018 - Researchers use neutrons to make first direct observations of water in lipid bilayers
September 23, 2018 - Researchers demonstrate pre-clinical success for universal flu vaccine in new paper
September 23, 2018 - Study reveals surprising gaps in some HIV medical providers’ knowledge of ACA
September 23, 2018 - Oxehealth secures European medical device accreditation for vital signs measurement software
September 23, 2018 - HTN Tx Intensification Common Upon Discharge in U.S. Vets
September 23, 2018 - Fibre can strengthen the intestinal barrier
September 23, 2018 - New platform examines infectious pathogens that may spread from animals to humans
September 23, 2018 - Demographers create detailed color map of population aging in Europe
September 23, 2018 - New type of fatty acid can slow down overreactive immune system
September 23, 2018 - Innovative procedure could provide breakthrough in treating early-stage lung cancer
September 23, 2018 - Research finds drop in number of measles cases in the EU/EEA since March 2018
September 23, 2018 - Researchers acquire new insights into DNA polymerases
September 23, 2018 - Alzheimer’s diagnosis might become simpler with new brain imaging method
September 23, 2018 - Reports Warn of Growing Opioid Crisis Among Seniors
September 23, 2018 - Researchers unravel why people with HIV suffer from more neurologic diseases
September 23, 2018 - Human brain structured to make best possible decision with limited resources
September 23, 2018 - KHN’s ‘What the Health?’ Health on the hill
September 23, 2018 - Bad air and inadequate data prove an unhealthy mix
September 23, 2018 - Regular bedtime and wake time important for heart, metabolic health even among adults
September 23, 2018 - HIV and a tale of a few cities
September 23, 2018 - NIH launches clinical trial to test infusions of combination antibodies in people with HIV
September 23, 2018 - Researchers develop new system to detect consumption of synthetic cannabinoids
September 23, 2018 - Vax-Hub to influenze radical change in development and manufacturing of vaccines
September 23, 2018 - People who have slept lesser than seven hours have higher risks of car crashes
September 23, 2018 - an ancient art may work best to prevent falls in old age
September 23, 2018 - Consumption of foods with lower nutritional quality related to increased cancer risk
September 23, 2018 - Patient Health Information Often Shared Electronically
September 23, 2018 - Can machine learning bring more humanity to health care?
September 23, 2018 - Body organs undergo structural changes in response to diet
September 23, 2018 - Genetic polymorphisms linked with muscle injury and stiffness
September 23, 2018 - As states try to rein in drug spending, feds slap down one bold Medicaid move
September 22, 2018 - Why Eczema Is Tougher to Treat for Black Patients
September 22, 2018 - Team reveals that human genome could contain up to 20 percent fewer genes
September 22, 2018 - USC research uncovers previously unknown genetic risk factor for Alzheimer’s disease
September 22, 2018 - Novel method achieves accurate and precise temperature estimation in fat-containing tissues
September 22, 2018 - BSI accredits Oxehealth’s vital signs measurement software as Class IIa medical device
September 22, 2018 - Evolution of psychiatric disorders and human personality traits
September 22, 2018 - Obesity in early puberty doubles asthma risk for boy’s future offspring
September 22, 2018 - World’s most advanced real-time patient monitoring platform receives key US patent
September 22, 2018 - Study explores connection between sexuality and cognitive status in older adults
September 22, 2018 - LSTM partners with TB Alliance to develop novel TB drug regimens
September 22, 2018 - Annual wellness visits improve delivery of preventive services in elderly population
September 22, 2018 - CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma
September 22, 2018 - Hispanic communities with high proportions of Hispanics face more cardiovascular-related death
September 22, 2018 - Vici syndrome – Genetics Home Reference
September 22, 2018 - Single-dose drug can shorten flu symptoms by about a day, studies suggest
September 22, 2018 - AMSBIO launches circulating tumor DNA Reference Standards
September 22, 2018 - Sandalwood mimicking odorant could stimulate hair growth in humans
September 22, 2018 - Overlooked immune cells could play a key role in cancer immunotherapy, claims new study
September 22, 2018 - Study reveals prevalence of diagnosed type 1 and type 2 diabetes among American adults
September 22, 2018 - Researchers develop fast detection strategy to know type of virus acquired by patients
September 22, 2018 - Global Prevalence of Insufficient Activity 27.5 Percent
September 22, 2018 - Strategies to protect bone health in hematologic stem cell transplant recipients
September 22, 2018 - Brigham Genomic Medicine program unravels 30 medical mysteries
September 22, 2018 - New system harnesses power of bubbles to destroy dangerous biofilms
September 22, 2018 - Inflammation plays crucial role in preventing heart attacks and strokes, study reveals
NYU Langone’s Perlmutter Cancer Center expands Blood and Marrow Transplant Program

NYU Langone’s Perlmutter Cancer Center expands Blood and Marrow Transplant Program

image_pdfDownload PDFimage_print

To further advance the study and treatment of blood cancers, Perlmutter Cancer Center at NYU Langone Health has significantly expanded its Blood and Marrow Transplant Program.

The program performs autologous and allogeneic transplants in adults and autologous transplants in children to treat the full spectrum of blood-borne cancers, including leukemia, lymphoma, and multiple myeloma. It recently received certification from the Foundation for the Accreditation of Cellular Therapy (FACT) to perform adult allogeneic transplants.

Autologous transplants involve using a patient’s own blood and blood by-products, while allogeneic transplants use those of an appropriate donor.

The Blood and Marrow Transplant Program is led by nationally renowned hematologist–oncologist, Samer Al-Homsi, MD, MBA, who joined Perlmutter Cancer Center-;one of the 70 cancer centers across the country designated by the National Institutes of Health-;in June 2017 to lead the program. Just in the past 12 months, more than 70 patients have received blood and marrow transplants at Perlmutter Cancer Center, which are performed in the specially designed Rita J. and Stanley H. Kaplan Stem Cell and Bone Marrow Transplant Center, located in the brand-new Kimmel Pavilion on NYU Langone’s main campus in Manhattan.

Based on pioneering work done at Johns Hopkins Cancer Center, the Blood and Marrow Transplant Program also offers haploidentical transplantation to patients. Haploidentical transplantation vastly expands the potential donor pool for patients who require a transplant.

“Typically, when you do a transplant, you need to have a full tissue match between the donor and recipient. Alternatively, we can now use haploidentical, or ‘half-match,’ transplants,” Dr. Al-Homsi says. “This transplant option will go a long way in overcoming the limitations of finding the right donor. Patients who have difficulty finding perfect matches will have more options, meaning that we can treat their cancer more effectively.”

Transplantation uses healthy hematopoietic precursor cells, or stem cells, to help fight cancer and replace unhealthy bone marrow.

Dr. Al-Homsi also does research that focuses on preventing graft-versus-host disease, or GvHD, a potentially life-threatening complication of blood and marrow transplant. He has led clinical trials examining innovative combinations of medications to prevent GvHD, including cyclophosphamide and proteasome inhibitors. Such combinations can prevent the use of other extended and burdensome prophylactic traditional agents and are applicable to people with limited kidney function, who are often denied blood and marrow transplants.

The Blood and Marrow Transplant Program works closely with the Clinical Leukemia Program at Perlmutter Cancer Center, led by Raoul Tibes, MD, PhD. Dr. Al-Homsi evaluates leukemia patients who require transplantation after their initial treatment provided by the hematologist–oncologists in the leukemia program.

“The Clinical Leukemia and Blood and Marrow Transplant programs really go hand-in-hand, and care for many of the same patients,” says Dr. Tibes. “We take a collaborative approach, helping patients from their first visit through their entire treatment. In many ways, one program cannot be fully effective without the other, and vice versa.”

“Our understanding of hematologic malignancies has advanced greatly over the past decade, to the point that many blood-borne cancers are curable,” says Benjamin G. Neel, MD, PhD, director of Perlmutter Cancer Center. “Bone marrow transplantation plays a critical role in these advances. Dr. Al-Homsi’s research holds tremendous promise to curtail negative interactions between host and transplanted cells and make this form of treatment safer and more effective.”

Tagged with:

About author

Related Articles