Breaking News
December 14, 2018 - Lack of peds preventive care ups unplanned hospital admissions
December 14, 2018 - Miscarriage: When Language Deepens Pain
December 14, 2018 - New method helps better understand pathological development of ALS
December 14, 2018 - Intellectually active lifestyle confers protection against neurodegeneration in Huntington’s patients
December 14, 2018 - Mammalian collagen nanofibrils become stronger and tougher with exercise
December 14, 2018 - Considerable Morbidity, Mortality Due to Animal Encounters
December 14, 2018 - Researchers find inhibiting one protein destroys toxic clumps seen in Parkinson’s disease
December 14, 2018 - How early physical therapy can lessen the long-term need for opioids
December 14, 2018 - Depression, suicide rates highest in Mountain West states
December 14, 2018 - New model could cure the potential to underestimate how quickly diseases spread
December 14, 2018 - Exercise-induced hormone activates cells critical for bone remodeling in mice
December 14, 2018 - Researchers discover new mechanism behind spread of malignant pleural mesothelioma
December 14, 2018 - Health Tip: Celebrate a Healthier Holiday
December 14, 2018 - Scalpel-free surgery enhances quality of life for Parkinson’s patients, study finds
December 14, 2018 - Early physical therapy can reduce risk, amount of long-term opioid use | News Center
December 14, 2018 - Genetic marker, predictor of early relapse in common childhood cancer discovered
December 14, 2018 - Study could lead to a potential new way of treating sepsis
December 14, 2018 - New protein complex helps embryonic stem cells to maintain their indefinite potential
December 14, 2018 - Salk professor receives $1.8 million from NOMIS Foundation for research on mechanisms to promote health
December 14, 2018 - New discovery will improve the safety and predictability of CRISPR
December 14, 2018 - Geneticists discover how sex-linked disorders arise
December 14, 2018 - New method to visualize small-molecule interactions inside cells
December 14, 2018 - Study describes mechanism that makes people more vulnerable to hunger-causing stimuli
December 14, 2018 - Chronic opioid therapy associated with increased healthcare spending and hospital stays
December 14, 2018 - Blood Types
December 14, 2018 - Obesity linked to increased risk of early-onset colorectal cancer
December 14, 2018 - Blood test helps identify distinct molecular signatures in children with cystic fibrosis
December 14, 2018 - Scientists use water to track electrical activity of nerve cells
December 14, 2018 - Recurrence of urinary tract infection may depend on bacterial strain, study shows
December 14, 2018 - GBT Announces U.S. FDA Agrees with its Proposal Relating to Accelerated Approval Pathway for Voxelotor for the Treatment of Sickle Cell Disease and GBT Plans to Submit New Drug Application (NDA)
December 14, 2018 - Partial Thromboplastin Time (PTT) Test: MedlinePlus Lab Test Information
December 14, 2018 - Common tactics for health promotion at work may be detrimental to employees with obesity
December 14, 2018 - Myths about migration and health not supported by available evidence
December 14, 2018 - Recent findings on rare genetic disorder may help develop new treatment options
December 14, 2018 - New drug shows promise in treating sarcomas
December 14, 2018 - Scientists perform lung lavage as new approach for tuberculosis diagnosis in rhinoceros
December 14, 2018 - Recent winners of the Nobel Medicine Prize
December 14, 2018 - KHN’s ‘What the Health?’ Insurance enrollment is lagging — and there are lots of reasons why
December 14, 2018 - Study assesses safety and efficacy of new treatment for pancreatic cancer
December 14, 2018 - Weakened metabolism of immune T cells may account for serious complications in elderly
December 14, 2018 - Study finds drug targets for Ebola, Dengue, and Zika viruses
December 14, 2018 - Face masks may offer protection against staph bacteria for hog farm workers and their household members
December 14, 2018 - Shining new light on neuron firing
December 14, 2018 - Study highlights need for personalized approach to treat ICU acquired delirium
December 14, 2018 - Soot particles from road traffic significantly contribute to air pollution
December 14, 2018 - Massage helps relieve pain, improve mobility in patients with knee osteoarthritis
December 14, 2018 - Researchers explore home healthcare nurses’ knowledge attitudes toward infection control
December 14, 2018 - Average outpatient visit in the U.S. costs nearly $500, shows new study
December 14, 2018 - Reference Infliximab, Biosimilar Equivalent for Crohn’s Disease
December 14, 2018 - New contact lens to treat eye injuries
December 14, 2018 - Acne could have a genetic basis find researchers promising new cure
December 14, 2018 - Higher physical activity associated with improved mood
December 14, 2018 - New UGA study points to optimal hypertension treatment for stroke patients
December 14, 2018 - Study highlights factors that can reduce food cravings
December 14, 2018 - Researchers discover Ebola-fighting protein in human cells
December 14, 2018 - Fentanyl surpasses heroin in cause of U.S. drug overdose deaths
December 14, 2018 - When Heart Attack Strikes, Women Often Hesitate to Call for Help
December 14, 2018 - A warning about costume contacts
December 14, 2018 - Study examines link between peripheral artery disease and heart attack
December 14, 2018 - Researchers develop biotechnological tool to produce antifungal proteins in plants
December 14, 2018 - 3D-printed adaptive aids can benefit patients with arthritis
December 14, 2018 - Chronic bullying during adolescence impacts mental health
December 14, 2018 - Integral Molecular and Merus collaborate to develop bispecific antibody therapeutics
December 13, 2018 - Importance of cell cycle and cellular senescence in the placenta discovered
December 13, 2018 - Gold “nanoprisms” open new window into vessels and single cells
December 13, 2018 - Research findings could lead to new targets for cancer-fighting therapeutics
December 13, 2018 - Butantan Institute signs collaboration agreement with MSD to develop dengue vaccines
December 13, 2018 - Study explores how patients want to discuss symptoms with doctors
December 13, 2018 - RUDN medics first to gather scattered data on hepatitis morbidity in Somalia
December 13, 2018 - Age and gender disparities found in use of bed nets to prevent malaria in sub-Saharan Africa
December 13, 2018 - Caffeine therapy benefits developing brains of premature babies
December 13, 2018 - New review focuses on electrospinning techniques used in musculoskeletal tissue engineering
December 13, 2018 - A new division focused on human immune system
December 13, 2018 - Zogenix Announces Positive Phase 3 Trial Results on the Efficacy and Safety of Fintepla (ZX008) in Dravet Syndrome
December 13, 2018 - BCR ABL Genetic Test: MedlinePlus Lab Test Information
December 13, 2018 - Caffeinated beverages during pregnancy linked to lower birth weight babies
December 13, 2018 - Stanford Medicine Health Trends Report examines opportunity to democratize health care
December 13, 2018 - Obsessive-compulsive disorder may protect individuals from obesity
December 13, 2018 - Scientists investigate how a painful event is processed in the brain
December 13, 2018 - Genetic study reveals new insights into underlying causes of moderate-to-severe asthma
UIC receives grant to reduce sexually transmitted infections among South African women

UIC receives grant to reduce sexually transmitted infections among South African women

image_pdfDownload PDFimage_print

The University of Illinois at Chicago is one of eight universities awarded funding by the National Institutes of Health to prevent and treat sexually transmitted infections, including HIV, among adolescents and young adults in Africa and Brazil. Collectively, the international projects are known as Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (PATC3H).

As one of the PATC3H participants, UIC received a two-year, $1.2 million grant to tailor a sexual education and skills-building program designed to help reduce the incidence of new sexually transmitted infections, including HIV, and increase HIV testing and linkage to care among South African adolescent girls and their female caregivers. In a randomized controlled study in Chicago, the program, called IMARA for Informed, Motivated, Aware, and Responsible about AIDS, reduced the risk of new STIs by 45 percent among black girls aged 14 to 18 years old compared to the control group.

“With this new grant, we will adapt IMARA to take into account the unique contextual factors and culture of South Africa,” said Geri Donenberg, professor of medicine and psychology at UIC and principal investigator on the grant.

The IMARA program includes education about sexually transmitted infections, including HIV, as well as communication skills that are designed to strengthen the mother/female caregiver-daughter bond. It also focuses on the importance of healthy peer and romantic relationships, effective parental monitoring, developing positive decision-making skills, and encourages participants to consider how the media and its portrayal of young black women influences their behavior, and how those behaviors may affect health outcomes.

“When this primary relationship in a young girl’s life is strong and positive, and communication is open, it has positive effects on the health of both of them, including, as we have shown, reducing the likelihood of acquiring a sexually transmitted infection,” said Donenberg, who is also director of the UIC Center for Dissemination and Implementation Science. “In many cases, the female caregiver is the mom, but it can also be another family member, like an aunt.”

In the first year of the grant, Donenberg, together with Dr. Linda-Gail Bekker, the chief operating officer of the Desmond Tutu HIV Foundation and deputy director of the Desmond Tutu HIV Centre at the University of Cape Town and a co-principal investigator of the grant, will enroll 48 pairs of adolescent girls and their female caregivers to participate in focus groups to help the researchers modify and tailor the IMARA program so that it is most relevant to their needs.

In the second year, the researchers will pilot-test the modified IMARA program with 50 female caregiver-daughter pairs at the Desmond Tutu HIV Foundation to ensure feasibility and acceptability of the adapted program. Participants who acquire sexually transmitted infections will be linked to care and provided treatment at the center.

At the conclusion of the pilot study, the investigators will work with policymakers to promote the potential benefits of IMARA and obtain support for broader scale-up should the program prove effective and cost-effective in the subsequent randomized controlled trial in years three to five of the study. “We are focused on building relationships with other medical centers and community organizations so that if the new IMARA program proves effective, we can rapidly scale it up to reach more people,” Donenberg said.

Based on the success of the first two years of the program, and hitting specific targets, Donenberg and her colleagues will receive an additional three years of funding from the National Institutes of Health to continue to evaluate the program in a randomized controlled trial with 525 daughter-female caregiver pairs. Participants will be tested for HIV and other sexually transmitted infections at the beginning of the study, and at six and 12 months after enrollment in the study. HIV testing and counseling and PrEP (pre-exposure prophylaxis) will be offered at each assessment, and participants interested in PrEP or who test positive for a sexually transmitted infection/HIV will receive treatment at the Foundation.

According to the Joint United Nations Programme on HIV/AIDS, an estimated 1.6 million people ages 15 and older worldwide were newly infected with HIV in 2017. South Africa has the world’s largest HIV epidemic and adolescent girls and young women acquire HIV at twice the rate of their male peers.

“As new infections continue to outpace access to and availability of drugs to prevent and treat HIV, primary prevention remains the most viable strategy to prevent new infections,” Donenberg said.

Source:

Reducing HIV, other STIs among young black women in South Africa

Tagged with:

About author

Related Articles