Breaking News
November 20, 2018 - Drug used to treat PTSD does not reduce suicidal thinking, may worsen nightmares and insomnia
November 20, 2018 - Molecular DNA analysis could facilitate more accurate prognosis, treatment of aggressive brain tumors
November 20, 2018 - Breast Cancer Recurrence Rate Not Up With Autologous Fat Transfer
November 20, 2018 - Beta 2 Microglobulin (B2M) Tumor Marker Test: MedlinePlus Lab Test Information
November 20, 2018 - Could bariatric surgery make men more virile?
November 20, 2018 - Urine test to check if patients take their medications will save the NHS money, say researchers
November 20, 2018 - Study reveals impact of residual inflammatory risk on clinical outcomes after PCI
November 20, 2018 - RNAi therapy shown to alleviate preeclampsia
November 20, 2018 - Replacement of dysfunctional microglia has therapeutic potential for neurodegenerative diseases
November 20, 2018 - Forming 3D Neuronal Models of the Brain
November 20, 2018 - Shoulder ultrasounds could be used to predict diabetes
November 20, 2018 - SGLT2 Inhibitors for Diabetes Linked to Increased Risk for Amputation
November 20, 2018 - Stem cell transplant cements Arizona men’s father-son bond
November 20, 2018 - Scientists try to develop portable systems that can quickly produce biologics on demand
November 20, 2018 - Automating Data Capture and Image Analysis in Continuous Experiments
November 20, 2018 - New drug shows promise for treating people with peanut allergy
November 20, 2018 - Researchers develop novel mouse model to study immunomodulatory therapies
November 20, 2018 - “Britain must not go backward on antibiotic controls to appease US trade deals” – Jim Moseley, CEO of Red Tractor
November 20, 2018 - Widespread errors in ‘proofreading’ cause inherited blindness
November 20, 2018 - Reaping the benefits of living longer
November 20, 2018 - New Program Hopes to Make Early Detection and Treatment of ALS a Reality
November 19, 2018 - Artificial bone-like substance mimics the way real bone grows at atomic level
November 19, 2018 - FDA Grants Orphan Drug Designation To RGX-181 Gene Therapy For The Treatment Of CLN2 Form Of Batten Disease
November 19, 2018 - Systemic mastocytosis – Genetics Home Reference
November 19, 2018 - Eye trauma secondary to falls in older adults increasing
November 19, 2018 - Empowering women in India to improve their health: A Q&A
November 19, 2018 - Researchers have trained a computer to analyze breast cancer images and classify tumors
November 19, 2018 - New glucose binding molecule could be key to better metabolic control for diabetics
November 19, 2018 - Biologists uncover novel genetic control of lipid maintenance and its potential connection to lifespan
November 19, 2018 - Warmer winters may set scene for higher rates of violent crimes
November 19, 2018 - Personalized program of physical exercise effective in reversing functional decline in the elderly
November 19, 2018 - Acacia Pharma Resubmits Barhemsys New Drug Application
November 19, 2018 - PDL1 (Immunotherapy) Tests: MedlinePlus Lab Test Information
November 19, 2018 - Transforming pregnancy research with a smartphone app
November 19, 2018 - Stanford Medicine magazine explores how digital technology is changing health care
November 19, 2018 - Vision impairments may increase risk of falls in older adults
November 19, 2018 - Concomitant use of sleeping pills and opioids found to prevalent among people with Alzheimer’s disease
November 19, 2018 - Marijuana prevention programs should focus on promoting mental wellbeing of youth
November 19, 2018 - New report calls for greater awareness and emphasis on scale and impact of atrial fibrillation
November 19, 2018 - In throes of turkey salmonella outbreak, don’t invite illness to your table
November 19, 2018 - UK health policies should be redesigned to become more accessible for men
November 19, 2018 - Short Interpregnancy Intervals Tied to Adverse Outcome Risk
November 19, 2018 - New mothers’ breastfeeding pain can affect infant health
November 19, 2018 - Stanford Medicine magazine reports on ways digital technology is transforming health care | News Center
November 19, 2018 - Human drugs alter cricket personality
November 19, 2018 - Insilico Medicine to introduce ‘Cure a disease in a year’ program at Biodata World Congress 2018
November 19, 2018 - Experts debate over whether gut or brain is more important in regulating appetite
November 19, 2018 - Playing on fear and fun, hospitals follow pharma in direct-to-consumer advertising
November 19, 2018 - 2PG Company receives grant to develop sensitive, low-cost molecular diagnostic tests for tuberculosis
November 19, 2018 - Low-Carb Diets May Work By Boosting Calorie Burn
November 19, 2018 - Key molecule responsible for learning and memory discovered
November 19, 2018 - New blood test developed for early diagnosis of ovarian cancer
November 19, 2018 - Researchers identify molecule to fight myotubular myopathy
November 19, 2018 - New solution to stop spread of brain cancer
November 19, 2018 - Immune cells trigger OCD-like behaviour in multiple sclerosis, study finds
November 19, 2018 - Scientists equip new virus that kills carcinoma cells with protein
November 19, 2018 - Novel approach could provide painless, efficient alternative for treating eye diseases
November 19, 2018 - Protein in cell membranes of sperm plays key role in finding their way to eggs
November 19, 2018 - Parents who decline flu vaccination for their child may be exposed to limited information
November 19, 2018 - Mirati Presents Data From Ongoing Phase 2 Clinical Trial Of Mocetinostat In Combination With Durvalumab At The SITC 33rd Annual Meeting
November 19, 2018 - FDA warns of common diabetes meds’ link to dangerous genital infection
November 19, 2018 - New methods for preserving shoulder function, quality of life in breast cancer patients
November 19, 2018 - Surprising discovery about BH4 may rekindle interest in once-promising pathway
November 19, 2018 - Nabriva Therapeutics Completes Submission of New Drug Application to U.S. Food and Drug Administration for Intravenous Contepo to Treat Complicated Urinary Tract Infections
November 19, 2018 - Beating breast cancer only to die of opioid use – a sad Appalachian story
November 19, 2018 - Workplace bullying or violence linked to higher risk of cardiovascular problems
November 19, 2018 - Changes in Risk Indicators of MetS Severity Tied to T2DM Risk
November 19, 2018 - ‘Game-changing’ skin sensor could improve life for a million hydrocephalus patients
November 19, 2018 - Alcohol ads on social media sites with pro-drinking comments increase desire to drink
November 19, 2018 - Neural networks could replace marker genes in RNA sequencing
November 19, 2018 - Obese adolescents feel less food enjoyment than those with normal weight, study reveals
November 18, 2018 - Goodbye ‘Gluten-Free’? Celiac Disease Vaccine May Make It Possible
November 18, 2018 - Skin ages when the main cells in the dermis lose their identity and function
November 18, 2018 - Rainforest vine compound makes pancreatic cancer cells susceptible to nutrient starvation
November 18, 2018 - A new mechanism in the control of inflammation
November 18, 2018 - Age-related decline in abstract reasoning ability predicts depressive symptoms over time
November 18, 2018 - Scientists succeed in increasing stability, biocompatibility of light-transducing nanoparticles
November 18, 2018 - Sugar, a ‘sweet’ tool to understand brain injuries
November 18, 2018 - Pharmacist-Led Effort Cuts Inappropriate Rx in Older Adults
November 18, 2018 - Novel discovery could lead to new cancer, autoimmune disease therapy
Artificial intelligence in opthamology

Artificial intelligence in opthamology

image_pdfDownload PDFimage_print
Credit: CC0 Public Domain

Around six years ago, high-resolution optical coherence tomography (OCT) was jointly developed by MedUni Vienna’s Center for Medical Physics and Biomedical Technology and its Department of Ophthalmology. OCT is an imaging technique that, like ultrasound – but contact-free – displays accurate stratified images of the retina. With the aid of algorithms recently developed at the Medical University of Vienna, it can be used to diagnose retinal diseases at an early stage within only a few seconds, so that the appropriate treatment can be given. Vienna is therefore regarded as a pioneer and also a driver of the digital revolution in ophthalmology, which now stands on the brink of a global breakthrough.

“In a cutting-edge paper, Google has now also taken up the theme that digital algorithms can provide accurate ophthalmic diagnoses fully automatically, in line with our developments and publications over the last few years,” explains Ursula Schmidt-Erfurth, Head of the Department of Ophthalmology and Optometrics. Google cited her studies conducted on this topic at MedUni Vienna four times in its Nature Medicine article.

The fact that Google, along with other technology companies like IBM, is now also jumping onto the digital bandwagon in ophthalmology is to be regarded as a positive step: “This helps to move on our concept of artificial intelligence in ophthalmology and to establish it as a business model throughout the world. It will very soon be possible for every ophthalmologist anywhere in the world to access our technology – which will benefit patients and help doctors.”

The pioneering role and leading position of the Vienna researchers were simultaneously recognised by a comprehensive review of the status of AI in the study and treatment of retinal diseases in the leading journal Progress in Retinal and Eye Research, to which the MedUni Vienna scientists were invited to contribute.

60 million pixels in 1.2 seconds

The OCT data are analysed using automated algorithms generated on the basis of artificial intelligence (AI). Both the equipment and the AI method were developed by the Medical University of Vienna, notably at the Center for Medical Physics and Biomedical Engineering and in the OPTIMA Christian Doppler laboratory, under the supervision of Schmidt-Erfurth. In 2017, Christoph Hitzenberger und Adolf Fercher from the Center for Medical Physics and Biomedical Engineering were awarded the Dolores H. Russ Prize, the “Nobel Prize for Engineering Sciences,” for the early development of OCT as a technique. This method captures 60 million pixels within 1.2 seconds and simultaneously analyses them. Says Schmidt-Erfurth: “The treating doctor can make use of this plethora of diagnostic data – and we are making this possible.”

If a disease is discovered or predicted, then the treating doctor is also able to initiate the correct therapeutic steps required for the patient, very much in the spirit of precision medicine or personalised medicine. “This will benefit each of the 170 million or so people suffering from macular degeneration,” says Schmidt-Erfurth. What is required is accurate analysis via digital medicine followed by individual treatment prescribed by the doctor for the individual patient at the right time.

Vision of the future: Automatic eye scanners

The first step is for all ophthalmologists and opticians to have access to digital opthalmic diagnostic techniques. The next step – and this is where Schmidt-Erfurth outlines a vision of the future, which the experts estimate might be realised in around three years time – is eye examination booths similar to the passport photograph booths found everywhere in the urban landscape. “This would allow everyone to scan their eyes anytime, anywhere and – if the result indicated a potential disease, go immediately to the appropriate doctor.”


Explore further:
Digital eye scan provides accurate picture of a person’s general health

More information:
Ursula Schmidt-Erfurth et al. Artificial intelligence in retina, Progress in Retinal and Eye Research (2018). DOI: 10.1016/j.preteyeres.2018.07.004

Journal reference:
Nature Medicine

Provided by:
Medical University of Vienna

About author

Related Articles