Breaking News
November 15, 2018 - CityU develops first microarrayed 3D neuronal culture platform
November 15, 2018 - Expert suggests ways to control uncomfortable vaginal symptoms in diabetic women
November 15, 2018 - New edition of Red Journal focuses on roles of imaging in radiation oncology
November 15, 2018 - Doctors Aren’t Promoting Breastfeeding’s Cancer-Protection Benefit
November 15, 2018 - Technique to ‘listen’ to a patient’s brain during tumour surgery
November 15, 2018 - Seven-year-old returns to life as a “normal, healthy child” following bone marrow transplant
November 15, 2018 - AMSBIO expands range of high quality FFPE cancer cell line controls
November 15, 2018 - Exploring NMR Spectroscopy Applications through Interesting Infographics
November 15, 2018 - Chapman University wins additional $2.9 million NIH grant to study Alzheimer’s disease
November 15, 2018 - Microgel powder reduces infection and promotes healing
November 15, 2018 - Suicidal patients with prescribed access to psychotropic drugs should be closely monitored
November 15, 2018 - Nitric oxide-releasing technology shows potential to reduce healing time of diabetic foot ulcers
November 15, 2018 - Mass shootings may trigger unnecessary blood donations
November 15, 2018 - From heart disease to cancer: New study tracks shift of county death rates
November 15, 2018 - Preventing falls with new sensor technology
November 15, 2018 - Promising technology could improve detection, diagnosis of fatal ovarian cancer
November 15, 2018 - AAP updates concussion recommendations for children and teens
November 15, 2018 - Two genomic tests help identify most effective treatment for breast cancer patients
November 15, 2018 - Researchers evaluate efficacy of salivary biomarkers for early detection of oral cancer
November 15, 2018 - NIH awards $3.5 million to continue development of robotic system for treating brain tumors
November 15, 2018 - Researchers succeed in building protein nanotubes from tiny scaffolds
November 15, 2018 - Rectal bleeding
November 15, 2018 - Nasal delivery of weight-loss hormone eases breathing problems in sleeping mice
November 15, 2018 - $9.6 million grant to fund research on vascular risk factors for brain aging, dementia | News Center
November 15, 2018 - Gum disease linked with diabetes
November 15, 2018 - Study identifies unique functional brain networks associated with ASD behaviors in infancy
November 15, 2018 - EU and industry-funded project aims to personalize diabetes treatment
November 15, 2018 - NIH researchers shed light on causes of HBV-associated acute liver failure
November 14, 2018 - FDA Alert: Implanted Pumps: Safety Communication
November 14, 2018 - Weight loss & acute Porphyria
November 14, 2018 - Researchers identify three sub-types of depression
November 14, 2018 - The puzzle of a mutated gene lurking behind many Parkinson’s cases | News Center
November 14, 2018 - The mystery viruses far worse than flu
November 14, 2018 - Research highlights physical changes in the brain of self-injuring teen girls
November 14, 2018 - Speed and error rate of DNA synthesis influenced by DNA structure
November 14, 2018 - Cranberry consumption modifies impact of animal-based diet on gut health
November 14, 2018 - £500,000 grant could pave way for new antibiotic to battle against drug-resistant superbugs
November 14, 2018 - Trump Administration Finalizes Birth Control Coverage Opt-Out
November 14, 2018 - Modern life offers children almost everything they need, except daylight
November 14, 2018 - Getting better: A patient is more than a collection of numbers
November 14, 2018 - 20 Americans Die Each Day Waiting For Organs
November 14, 2018 - First bifacial molecule can invade double-stranded DNA or RNA
November 14, 2018 - Study finds lack of safety data for using flowers in cooking
November 14, 2018 - Statistical methods play key role in predicting efficacy of new drugs
November 14, 2018 - Research explores how exercise may help fight drug addiction
November 14, 2018 - Health Tip: Limit Fat, Sugar and Salt in Your Child’s Diet
November 14, 2018 - CA 19-9 Blood Test (Pancreatic Cancer): MedlinePlus Lab Test Information
November 14, 2018 - Old drug could have new use helping sick premature babies
November 14, 2018 - Surgery, not antibiotics, should remain first-line treatment for appendicitis | News Center
November 14, 2018 - Researchers to develop sports-specific classification system for blind football
November 14, 2018 - Preschool children show awake responses to naptime nonsense words
November 14, 2018 - Researchers develop innovative treatment to repair damaged brain tissues
November 14, 2018 - Survey shows negative effect of vulvovaginal atrophy symptoms on quality of life for women
November 14, 2018 - Study sheds light on mechanisms that prevent autoimmune attack
November 14, 2018 - Sleep quality found to be worse for women who undergo surgical menopause
November 14, 2018 - One-hour cognitive behavioral therapy session reduces insomnia symptoms in prisoners
November 14, 2018 - New study provides deeper insight into chromosome segregation during mitosis
November 14, 2018 - Surgical menopause leads to more disrupted sleep than natural menopause
November 14, 2018 - Inhibition of one protein clears toxic clumps seen in Parkinson’s disease, study finds
November 14, 2018 - Appendix removal is linked to lower risk of Parkinson’s
November 14, 2018 - Lifting weights for less than an hour a week may reduce cardiovascular disease risk
November 14, 2018 - Pulmonary rehabilitation rarely received by hospitalized COPD patients despite health benefits
November 14, 2018 - New anti-HER2 drug shows promising anti-tumor activity in gullet, stomach and bowel cancers
November 14, 2018 - Regular head circumference assessment of preterm babies can help identify long-term IQ problems
November 14, 2018 - Brigham investigators examine opioid use among Massachusetts adolescents, prescription trends
November 14, 2018 - Study defines biomarker in response to treatment of castration-resistant prostate cancer
November 14, 2018 - Study identifies potential therapeutic strategy for patients with clear cell renal cancer
November 14, 2018 - Bausch Health Announces U.S. Launch of Bryhali (halobetasol propionate) Lotion, 0.01%, for Plaque Psoriasis In Adults
November 14, 2018 - Alpha Fetoprotein (AFP) Tumor Marker Test: MedlinePlus Lab Test Information
November 14, 2018 - Researchers evaluate controversial treatment for Parkinson’s disease psychosis
November 14, 2018 - AI could help veterinarians code their notes
November 14, 2018 - Pre-schoolers with autism thrive in mainstream classroom settings
November 14, 2018 - Individual and work-related factors may help promote hospital physician engagement, finds study
November 14, 2018 - Complementary and alternative medicine is widely used by general population in England
November 14, 2018 - Study reveals link between tobacco availability and smoking during pregnancy
November 14, 2018 - Purdue researchers develop translucent base for silicon patches to deliver exact doses of biomolecules
November 14, 2018 - New technology based on moths and magnets could help treat genetic diseases
November 14, 2018 - Concussion-Related Biomarkers Vary Based on Sex, Race
November 14, 2018 - One more year of high school may shape waistlines later in life
November 14, 2018 - Dissecting high drug costs – Scope
October 2018 Briefing – Pathology

October 2018 Briefing – Pathology

image_pdfDownload PDFimage_print

Here are what the editors at HealthDay consider to be the most important developments in Pathology for October 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Barriers to Prostate Cancer Research in Black Men Identified

WEDNESDAY, Oct. 31, 2018 — A lack of understanding of terminology, health care system distrust, and a lack of prostate cancer knowledge are among the barriers to genomic testing for prostate cancer and prostate cancer research participation among black men, according to a study published in the November issue of the American Journal of Preventive Medicine.

Abstract/Full Text

Antibiotics, Acid Suppressants in Infancy May Up Obesity Risk

WEDNESDAY, Oct. 31, 2018 — Prescription of antibiotics and acid-suppressing medications in early childhood is associated with an increased risk for obesity, according to a study published online Oct. 30 in Gut.

Abstract/Full Text

Genetic Risk Score IDs Breast CA Risk in Female Child CA Survivors

WEDNESDAY, Oct. 31, 2018 — A polygenic risk score (PRS) can identify subsequent breast cancer risk among childhood survivors of cancer, according to a study published online Oct. 26 in Clinical Cancer Research.

Abstract/Full Text (subscription or payment may be required)

AMA Announces Initiative to Reinvent Physician Training

TUESDAY, Oct. 30, 2018 — The American Medical Association (AMA) today announced a new $15 million competitive grant initiative, the “Reimagining Residency” initiative, aimed at improving residency training.

More Information

Guidelines Presented for Lumbar Puncture in Alzheimer’s Dx

TUESDAY, Oct. 30, 2018 — The Alzheimer’s Association has released appropriate-use criteria for lumbar puncture and cerebrospinal fluid (CSF) testing in Alzheimer’s disease diagnosis, according to a review article published online Oct. 10 in Alzheimer’s & Dementia.

Abstract/Full Text

Many Hospitals Noncompliant With Record Request Regulations

MONDAY, Oct. 29, 2018 — Among top-ranked U.S. hospitals, data reveal discrepancies in information provided to patients regarding medical records release processes as well as noncompliance with state and federal regulations, according to a study published online Oct. 5 in JAMA Network Open.

Abstract/Full Text

Hypofractionated Radiation OK for Localized Prostate CA

MONDAY, Oct. 29, 2018 — A new clinical guideline for early-stage prostate cancer supports the use of shortened courses of radiation therapy, according to an article published in Practical Radiation Oncology.

Abstract/Full Text

Trump Administration Announces Plan to Cut Drug Prices

FRIDAY, Oct. 26, 2018 — In an effort to cut high drug costs, the prices paid by Medicare for certain prescription drugs would be based on those in other advanced industrial nations, according to a proposal announced Oct. 25 by the Trump administration.

HHS Study
New York Times Article

Pace of Change Has Accelerated in Alternative Payment Models

THURSDAY, Oct. 25, 2018 — The impact of alternative payment models (APMs) on physician practices has been described in a study published by the RAND Corp. and the American Medical Association.

More Information

Arthritis in Adulthood Linked to Childhood Maltreatment

WEDNESDAY, Oct. 24, 2018 — The prevalence of arthritis is higher among adults who experience severe and/or frequent childhood maltreatment, according to a study published online Oct. 17 in Arthritis Care & Research.

Abstract/Full Text (subscription or payment may be required)

White House Unveils New Insurance Option for Small Firms

TUESDAY, Oct. 23, 2018 — A plan to allow small businesses to use tax-free accounts to provide health coverage for employees was announced today by the Trump administration.

AP News Article
More Information

Intensive SBP Tx Cuts Kidney Damage Biomarkers in Incident CKD

TUESDAY, Oct. 23, 2018 — Patients with incident chronic kidney disease (CKD) in the setting of intensive systolic blood pressure (SBP) treatment have decreases rather than increases in kidney damage biomarkers, according to a study published online Oct. 23 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

CDC: First U.S. Case of Rat-Borne Andes Virus Diagnosed

FRIDAY, Oct. 19, 2018 — The first confirmed U.S. case of a virus carried by South American rodents occurred earlier this year, the U.S. Centers for Disease Control and Prevention says.

CNN Article
CDC Case Report

Bioinformatics Tool Can ID Source of Bloodstream Pathogens

FRIDAY, Oct. 19, 2018 — A streamlined bioinformatics tool can match bloodstream pathogens to a candidate source, according to a study published online Oct. 15 in Nature Medicine.

Abstract/Full Text (subscription or payment may be required)

Triple Combo Regimens May Address Cause of Cystic Fibrosis

FRIDAY, Oct. 19, 2018 — Triple therapy with VX-659 or VX-445 combined with tezacaftor-ivacaftor shows promise for the treatment of adult patients with cystic fibrosis who have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), according to two studies published online Oct. 18 in the New England Journal of Medicine. The studies were published to coincide with a presentation at the annual North American Cystic Fibrosis Conference, held from Oct. 18 to 20 in Denver.

Abstract/Full Text – Davies
Abstract/Full Text – Keating
Editorial
More Information

WHO: Congo Ebola Outbreak Not a Global Emergency

THURSDAY, Oct. 18, 2018 — The latest Ebola outbreak in Congo is not yet severe enough to be declared a global emergency, the World Health Organization decided after a meeting of experts yesterday.

AP News Article
More Information

Clostridium difficile Spores Survive Laundering of Sheets

WEDNESDAY, Oct. 17, 2018 — Clostridium difficile spores are able to survive laundering through a commercial washer extractor, according to a study published online Oct. 16 in Infection Control & Hospital Epidemiology.

Abstract/Full Text

Procurement Requirements Drive Interoperability in Health Care IT

THURSDAY, Oct. 18, 2018 — Interoperability of health care information technology (IT) must be improved to facilitate creation of a fully integrated health care system that can improve health and health care at lower cost, according to a report published by the National Academy of Medicine.

More Information

Limited Evidence for OTC Preps to Treat Nasal Symptoms of Colds

THURSDAY, Oct. 18, 2018 — Limited evidence is available for over-the-counter (OTC) treatments for nasal symptoms of the common cold, according to a report published online Oct. 10 in The BMJ.

Abstract/Full Text

Plasma-Based Genotyping Aids Targeted Tx of Metastatic NSCLC

THURSDAY, Oct. 18, 2018 — Integration of plasma next-generation sequencing (NGS) into the routine management of metastatic non-small cell lung cancer (NSCLC) results in an increase in the detection of therapeutically targetable mutations, according to a study published online Oct. 11 in JAMA Oncology.

Abstract/Full Text
Editorial

Positive HPV Status Tied to Better Cervical Cancer Prognosis

TUESDAY, Oct. 16, 2018 — Women with high-risk human papillomavirus (hrHPV)-positive cervical tumors have a substantially better prognosis than women with hrHPV-negative tumors, according to a study published online Oct. 1 in PLOS Medicine.

Abstract/Full Text

Without Medicaid Expansion, Poor Patients Forgo Medical Care

MONDAY, Oct. 15, 2018 — Doing without medical care is much more common among low-income residents of states that have not expanded Medicaid than among low-income people in other states, according to a Government Accountability Office report.

AP News Article

FDA Approves New DNA-Based Test to Verify Blood Compatibility

FRIDAY, Oct. 12, 2018 — The U.S. Food and Drug Administration has approved the ID CORE XT DNA-based test to help doctors verify blood compatibility before a transfusion.

More Information

Zoledronate Lowers Fracture Risk in Women With Osteopenia

FRIDAY, Oct. 12, 2018 — The risk for fragility fractures is significantly lower in women with osteopenia who receive zoledronate than in those who receive placebo, according to a study published online Oct. 1 in the New England Journal of Medicine.

Abstract/Full Text

High Circulating Prolactin Level Inversely Linked to T2DM Risk

FRIDAY, Oct. 12, 2018 — Among U.S. women, a normally high circulating prolactin concentration is associated with a reduced risk for type 2 diabetes, according to a study published online Oct. 11 in Diabetologia.

Abstract/Full Text (subscription or payment may be required)

Diet Less Important Than Genes for High Serum Urate Levels

THURSDAY, Oct. 11, 2018 — Diet explains little of the variation in serum urate levels in the general population, while genetic factors make a greater contribution, according to a meta-analysis published online Oct. 10 in The BMJ.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Wall Thickness Measured by MRI More Consistently Linked to CVD

THURSDAY, Oct. 11, 2018 — Common carotid artery (CCA) wall thickness measured using magnetic resonance imaging (MRI) is more consistently associated with incident cardiovascular disease (CVD) outcomes than intima-media thickness measured by ultrasound, according to a study published online Oct. 9 in Radiology.

Abstract/Full Text

Aetna-CVS Merger Approved

WEDNESDAY, Oct. 10, 2018 — A $69 billion merger between health insurer Aetna and pharmacy manager CVS Health has been approved, according to the U.S. Justice Department.

The New York Times Article

Mechanical Ventilation May Alter Diaphragm Muscle Fibers

TUESDAY, Oct. 9, 2018 — In critically ill patients, mechanical ventilation with positive end-expiratory pressure (PEEP) results in reduced diaphragm fiber length that may make it more difficult to wean patients from mechanical ventilation, according to a study published in the Aug. 15 issue of the American Journal of Respiratory and Critical Care Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Minority Residents Experience Burdens Linked to Race/Ethnicity

TUESDAY, Oct. 9 2018 — Minority residents describe burdens associated with race/ethnicity, including microaggressions and bias on a daily basis, according to a study published online Sept. 28 in JAMA Network Open.

Abstract/Full Text
Editorial

Integrated Classifier Identifies Benign Lung Nodules

TUESDAY, Oct. 9, 2018 — An integrated plasma proteomics classifier, which integrates the relative abundance of two plasma proteins with a clinical risk prediction model, can distinguish benign from malignant lung nodules in those at low-to-intermediate risk for cancer, according to a study published in the September issue of CHEST.

Abstract/Full Text
Editorial

Industry-Funded Trials Often Involve Employees in Studies

FRIDAY, Oct. 5, 2018 — Industry employees are often involved in the design, conduct, and reporting of industry-funded trials in high-impact journals, according to a study published online Oct. 3 in The BMJ.

Abstract/Full Text
Editorial

Tips Provided for Budgeting in Medical Residency

THURSDAY, Oct. 4, 2018 — Medical residents should start budgeting and save for the future, according to an article published in the American Medical Association AMA Wire.

More Information

Three-Quarters of Health Care Workers Got Flu Shot Last Year

THURSDAY, Oct. 4, 2018 — Just over three-quarters of health care personnel received a flu vaccine last season, according to research published in the Sept. 28 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Genomic Screening Can ID Undetected BRCA1/2 Cancer Risk

THURSDAY, Oct. 4, 2018 — Exome sequencing-based screening may identify pathogenic and likely pathogenic (P/LP) BRCA1/2 variants that might otherwise remain undetected, according to a study published online Sept. 21 in JAMA Network Open.

Abstract/Full Text

Uninsured Rate at 8.8 Percent in First Quarter of 2018

WEDNESDAY, Oct. 3, 2018 — In the first quarter of 2018, the uninsured rate was 8.8 percent, not significantly different from a year earlier, according to a report released Aug. 29 by the National Center for Health Statistics (NCHS).

Abstract/Full Text

For Employer-Based Plans, Spending Across Services Steady

TUESDAY, Oct. 2, 2018 — Despite large health policy changes, the distribution of spending across service areas has remained fairly consistent over the past 10 years for those enrolled in employer-sponsored insurance, according to a study published in the October issue of Health Affairs.

Abstract/Full Text (subscription or payment may be required)

Negligible Drop in Neoplastic Lesion Dx After First Round of FIT

TUESDAY, Oct. 2, 2018 — After the first round of a fecal immunochemical test (FIT)-based, multiple-round, long-term screening program, there is a negligible reduction in detection rates for neoplastic lesions in the proximal versus the distal colon, according to a study published online Oct. 2 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Second Opinion at NCI Center Valuable for Breast CA Patients

TUESDAY, Oct. 2, 2018 — Almost 43 percent of patients diagnosed with breast cancer presenting to a National Cancer Institute (NCI)-designated cancer center for a second opinion have a change in diagnosis, according to a study published in the October issue of the Annals of Surgical Oncology.

Abstract/Full Text

Interviews Can Help Ensure Physician Candidates Fit Culture

TUESDAY, Oct. 2, 2018 — In preparing to interview to hire a new physician, practices must understand their own cultures, according to an article published in Medical Economics.

Abstract/Full Text

Number of Health-Related Data Breaches Increasing

TUESDAY, Oct. 2, 2018 — The number of health data breaches has steadily increased since 2010, according to a research letter published in the Sept. 25 issue of the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

First Human Case of Rat Strain of Hepatitis E Seen in Hong Kong

MONDAY, Oct. 1, 2018 — The first human case of a strain of hepatitis E previously found only in rats was diagnosed in a Hong Kong man who received a liver transplant in May 2017.

The New York Times Article

WHO: ‘Very High Risk’ That Ebola Will Spread From Congo

MONDAY, Oct. 1, 2018 — There is a “very high” risk that the latest Ebola outbreak in Congo will spread beyond that nation’s borders, the World Health Organization warns.

AP News Article
More Information

Hospital Privacy Curtains Become Increasingly Contaminated

MONDAY, Oct. 1, 2018 — Curtains surrounding patient beds become progressively contaminated with bacteria, according to a study published in the September issue of the American Journal of Infection Control.

Abstract/Full Text

Risk of Relapse Up for Teens, Young Adults With Leukemia

MONDAY, Oct. 1, 2018 — Adolescents and young adults (AYA; aged 15 to 39 years) with acute lymphoblastic leukemia (ALL) have increased risk of on-therapy relapse and relapse after completing therapy compared with children with ALL, according to a study published online Sept. 27 in Cancer Epidemiology, Biomarkers & Prevention.

Abstract/Full Text (subscription or payment may be required)

More Non-Elderly Americans Uninsured in 2017 Versus 2016

MONDAY, Oct. 1, 2018 — From 2016 to 2017, there was an increase in the number of uninsured non-elderly Americans, according to a report published by the Robert Wood Johnson Foundation.

More Information

Genetics May Identify Type 2 Diabetes Subtypes

MONDAY, Oct. 1, 2018 — Clusters of type 2 diabetes (T2D) loci and traits have been identified, according to a study published online Sept. 21 in PLOS Medicine.

Abstract/Full Text

© 2018 HealthDay. All rights reserved.

Posted: November 2018

Tagged with:

About author

Related Articles