Breaking News
December 13, 2018 - Novel way to efficiently deliver anti-parasitic medicines
December 13, 2018 - RKI publishes new data on disease prevention and utilization of medical services
December 13, 2018 - High-tech, flexible patches sewn into clothes could help to stay warm
December 13, 2018 - Restoring Hair Growth on Scarred Skin? Mouse Study Could Show the Way
December 13, 2018 - Probiotic use may reduce antibiotic prescriptions, researchers say
December 13, 2018 - Drug repositioning strategy identifies potential new treatments for epilepsy
December 13, 2018 - Chronic rhinitis associated with hospital readmissions for asthma and COPD patients
December 13, 2018 - Food poisoning discovery could save lives
December 13, 2018 - Cloned antibodies show potential to treat, diagnose life-threatening fungal infections
December 13, 2018 - Exercise may reduce colorectal cancer risk after weight loss
December 13, 2018 - Russian scientists create hardware-information system for brain disorders treatment
December 13, 2018 - Moderate alcohol consumption linked with lower risk of hospitalization
December 13, 2018 - Nurturing Healthy Neighborhoods | NIH News in Health
December 13, 2018 - Rise in meth and opioid use during pregnancy
December 13, 2018 - Researchers gain new insights into pediatric tumors
December 13, 2018 - FSU study finds racial disparity among adolescents receiving flu vaccine
December 13, 2018 - Drug cocktail induces cancer cell death by switching off energy supply
December 13, 2018 - Baculovirus virion completely eliminates liver-stage parasites in mouse model
December 13, 2018 - Researchers create noninvasive technology that detects when nerve cells fire
December 13, 2018 - Inability to do daily living tasks delays discharge of mental health patients
December 13, 2018 - Treating patients with hypertension induced albuminuria
December 13, 2018 - New substance could improve efficacy of established breast cancer treatments
December 13, 2018 - Scientists develop new stem cell line to study conversion of stem cells into muscle
December 13, 2018 - Re-programming the body’s energy pathway boosts kidney self-repair
December 13, 2018 - Research findings could help improve treatment of anxiety and post-traumatic stress disorders
December 13, 2018 - The Microbiome Movement announce Microbiotica as official industry partner
December 13, 2018 - New study reveals potential benefits of cEEG monitoring for infant ICU patients
December 13, 2018 - Whole-body imaging PET/MRI offers information to guide treatment options for prostate cancer
December 13, 2018 - International investigators fight against the negative campaign on benzodiazepines
December 13, 2018 - Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders
December 13, 2018 - FDA Approves Tolsura (SUBA®-itraconazole capsules) for the Treatment of Certain Fungal Infections
December 13, 2018 - Are scientists studying the wrong kind of mice?
December 13, 2018 - Computer memory: A scientific team builds a virtual model of a key brain region
December 13, 2018 - Visual inspection alone is insufficient to diagnose skin cancer
December 13, 2018 - Paternal grandfather’s access to food associated with grandson’s mortality risk
December 13, 2018 - Our brain senses angry voices in a flash, study shows
December 13, 2018 - PM2.5 Exposure Linked to Asthma Rescue Medication Use
December 13, 2018 - Can’t exercise? A hot bath may help improve inflammation, metabolism, study suggests
December 13, 2018 - Can artificial intelligence help doctors with the human side of medicine?
December 13, 2018 - Virginia Tech and UC San Diego researchers team up to develop nonopioid drug for chronic pain
December 13, 2018 - NIH offers support for HIV care and prevention research in the southern United States
December 12, 2018 - Activating brain region could revive the urge to socialize among opioid addicts
December 12, 2018 - Relationship impairment appears to interfere with seeking mental health treatment in men
December 12, 2018 - Sleep, Don’t Cram, Before Finals for Better Grades
December 12, 2018 - Effective treatments for urticarial vasculitis
December 12, 2018 - Gun violence is a public health issue: One physician’s story
December 12, 2018 - The Science of Healthy Aging
December 12, 2018 - Yes to yoghurt and cheese: New improved Mediterranean diet
December 12, 2018 - Researchers uncover a number of previously unknown insecticide resistance mechanisms
December 12, 2018 - Regulating the immune system’s ‘regulator’
December 12, 2018 - In breaking bad news, the comfort of silence
December 12, 2018 - Study finds upward link between alcohol consumption and physical activity in college students
December 12, 2018 - FDA issues warning letter to Zhejiang Huahai Pharmaceutical involved in valsartan recall
December 12, 2018 - Weight history at ages 20 and 40 could help predict patients’ future risk of heart failure
December 12, 2018 - Presence of antiphospholipid antibodies tied to first-time MI
December 12, 2018 - DNA analysis finds that stethoscopes are teaming with bacteria
December 12, 2018 - New study could help inform research on preventing falls
December 12, 2018 - Women and men with heart attack symptoms receive different care from EMS
December 12, 2018 - Disrupted biological clock can contribute to onset of diseases, USC study shows
December 12, 2018 - New publications generate controversy over the value of reducing salt consumption in populations
December 12, 2018 - New data from TAILORx trial confirms lack of chemo benefit regardless of race or ethnicity
December 12, 2018 - Specific class of biomarkers can accurately indicate the severity of cancer
December 12, 2018 - Meds Taken Do Not Vary With ADL Impairment in Heart Failure
December 12, 2018 - Long-term study shows that HIV-2 is deadlier than previously thought
December 12, 2018 - People living near oil and gas wells show early signs of cardiovascular disease
December 12, 2018 - IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony
December 12, 2018 - People who eat red meat have high levels of chemical associated with heart disease, study finds
December 12, 2018 - New method uses water molecules to unlock neurons’ secrets
December 12, 2018 - Genetics study offers hope for new acne treatment
December 12, 2018 - New computer model predicts prostate cancer progression
December 12, 2018 - Nobel Laureates lecture about immune checkpoint therapy for cancer treatment
December 12, 2018 - More Illnesses From Tainted Romaine Lettuce Reported
December 12, 2018 - Aspirin could reduce HIV infections in women
December 12, 2018 - The EORTC Brain Tumor Group and Protagen AG collaborate to study immuno-competence of long-term glioblastoma survivors
December 12, 2018 - Insights into magnetotactic bacteria could guide development of biological nanorobots
December 12, 2018 - Sacrificial immune cells alert body to infection
December 12, 2018 - Low-salt diet may be more beneficial for females than males
December 12, 2018 - Major soil organic matter compound battles chronic wasting disease
December 12, 2018 - Findings may open up new ways to treat dwarfism and other ER-stress-related conditions
December 12, 2018 - New computational model provides clearer picture of shape-changing cells’ structure and mechanics
Report reveals increase in pancreatic cancer death rates across Europe

Report reveals increase in pancreatic cancer death rates across Europe

image_pdfDownload PDFimage_print

Pancreatic cancer death rates in the European Union (EU) have increased by 5% between 1990 and 2016, a report launched today reveals. This is the highest increase in any of the EU’s top five cancer killers which, as well as pancreatic cancer, includes lung, colorectal, breast and prostate cancer. 

Number of Pancreatic Cancer Deaths in EU (1990-2016)

‘Pancreatic Cancer Across Europe’, published by United European Gastroenterology (UEG) to coincide with World Pancreatic Cancer Day, examines the past and current state of pancreatic cancer care and treatment, as well as the future prospects, such as targeting the microbiome, for improving the prognosis for patients. Whilst lung, breast and colorectal cancer have seen significant reductions in death rates since 1990, deaths from pancreatic cancer continue to rise. Experts also believe that pancreatic cancer has now overtaken breast cancer as the third leading cause of death from cancer in the EU.

% Change in Pancreatic Cancer Death Rates Across EU28 (1990-2016)

Cancer Site

1990 Death Rate

2016 Death Rate

% Change Between 1990 and 2016

Breast cancer

14.82

11.11

-25%

Tracheal, bronchial and lung cancer

37.77

30.30

-20%

Colorectal cancer

21.80

18.72

-14%

Prostate cancer

8.74

8.83

+1%

Pancreatic cancer

9.30

9.72

+5%

Despite the rise in death rates and dreadfully low survival rates, pancreatic cancer receives less than 2% of all cancer research funding in Europe. Markus Peck, UEG expert, explains:Pancreatic cancer has the lowest survival of all cancers in Europe. Now responsible for over 95,000 EU deaths every year, the median survival time at the point of diagnosis is just 4.6 months, with patients losing 98% of their healthy life expectancy. Often referred to as ‘the silent killer’, symptoms can be hard to identify, thus making it difficult to diagnose the disease early which is essential for life-saving surgery.

If we are to take a stand against the continent’s deadliest cancer, we must address the insufficient research funding; that is where the European Union can lead the way. Whilst medical and scientific innovations have positively changed the prospects for many cancer patients, those diagnosed with pancreatic cancer have not been blessed with much clinically meaningful progress. To deliver earlier diagnoses and improved treatments we need to engage now in more basic as well as applied research to see real progress for our patients in the years to come.”

Microbiome – the key to turning the tide?

After forty years of limited progress in pancreatic cancer research, experts claim that new treatment options could finally be on the horizon as researchers investigate how changing the pancreas’ microbiome may help to slow tumor growth and enable the body to develop its own ‘defense mechanism’. The microbial population of a cancerous pancreas has been found to be approximately 1,000 times larger than that of a non-cancerous pancreas and research has shown that removing bacteria from the gut and pancreas slowed cancer growth and ‘reprogrammed’ immune cells to react against cancer cells.

This development could lead to significant changes in clinical practice as removing bacterial species could improve the efficacy of chemotherapy or immunotherapy, offering hope that clinicians will finally be able to slow tumor growth, alter metastatic behavior and ultimately change the disease’s progression.

Professor Thomas Seufferlein, pancreatic cancer expert, comments:

Research looking at the impact of the microbiome on pancreatic cancer is a particularly exciting new area, as the pancreas was previously thought of as a sterile organ. Such research will also improve our understanding of the microenvironment in a metastatic setting and how the tumor responds to its environment. This will inform the metastatic behavior and ultimately alter disease progression.”

“With continued investment in pancreatic cancer research, we should have new, important findings within the next five years and, hopefully, find that targeting the microbiome as well as tumor cells will significantly improve treatment outcomes and reduce death rates”, adds Professor Seufferlein.

Source:

https://www.ueg.eu/press/releases/ueg-press-release/article/pancreatic-cancer-death-rates-rising-across-europe-report-reveals/?type=&cHash=5e2d058cdf0da6406f24f5ccb7bc744c

Tagged with:

About author

Related Articles