Breaking News
February 20, 2019 - Study sheds new light on how antibiotic resistance genes are transferred between bacteria
February 20, 2019 - Chronic Wasting Disease may soon spread to humans, warns CDC
February 20, 2019 - Scientists identify new genetic causes linked to abnormal pregnancies and miscarriages
February 20, 2019 - Using LyoSpeed technology to avoid residual solvent when drying HPLC fractions
February 20, 2019 - New screening tool more likely to identify sexual and labor exploitation of youth
February 20, 2019 - Newly licensed nurses work for long hours, also have a second paid job
February 20, 2019 - Physicists identify simple mechanism used by deadly bacteria to fend off antibiotics
February 20, 2019 - FDA Grants Priority Review to Genentech’s Personalized Medicine Entrectinib
February 20, 2019 - Exposure to chemicals before and after birth is associated with a decrease in lung function
February 20, 2019 - Neuroscientists reveal that simple brain region can guide complex feats of mental activity
February 20, 2019 - Study finds new link between food allergies and multiple sclerosis
February 20, 2019 - First gene therapy operation for macular degeneration is a success
February 20, 2019 - Physicians graduated outside the U.S. offer better care for Medicare patients with complex needs
February 20, 2019 - FDA Approves Keytruda (pembrolizumab) for the Adjuvant Treatment of Patients with Melanoma with Involvement of Lymph Node(s) Following Complete Resection
February 20, 2019 - Study identifies brain cells that modulate behavioral response to threats
February 20, 2019 - Researchers take closer look at how viruses bind cells and cause infection
February 20, 2019 - Newly developed gene therapy helps decelerate aging process
February 20, 2019 - Study suggests new treatment strategy for deadly brain cancer
February 20, 2019 - Scientists develop unique hybrid implant that imitates bone structure
February 20, 2019 - Push-ups can be tailored to meet specific needs of individuals
February 20, 2019 - Early-career job loss has long term health implications
February 20, 2019 - CVD Does Not Modify Depression-Mortality Link in Elderly
February 20, 2019 - Electrical activity early in fruit flies’ brain development could shed light on how neurons wire the brain
February 20, 2019 - Machine learning technique helps predict which asthma patients respond to corticosteroid therapy
February 20, 2019 - Self-reported sleep duration is a useful tool to measure sleep in children, study suggests
February 20, 2019 - T-cells play key role in how the body fights follicular lymphoma
February 20, 2019 - Study shows how 3D organization of genetic material helps perpetuate the species
February 20, 2019 - Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells
February 20, 2019 - Study reveals major sex differences in management of cardiovascular risk factors among U.S. adults
February 20, 2019 - Health Tip: Get Your Child to School on Time
February 20, 2019 - Shortcut strategy for screening compounds with clinical potentials for drug development
February 20, 2019 - Common acid reflux drugs tied to elevated risk for kidney disease
February 20, 2019 - Microbiome could be culprit when good drugs do harm
February 20, 2019 - Prenatal exposure to forest fires causes stunted growth in children
February 20, 2019 - Gene therapy restores hearing in mice with congenital genetic deafness
February 20, 2019 - First molecular test predicts treatment response for kidney cancer
February 20, 2019 - New method for improved visualization of single-cell RNA- sequencing data
February 20, 2019 - Researchers capture altered brain activity patterns of Parkinson’s in mice
February 20, 2019 - A possible blood test for detecting Alzheimer’s disease before symptoms show
February 20, 2019 - Primary care physicians associated with longevity, new research finds
February 19, 2019 - New study identifies many key lessons to establish sanctioned safe consumption sites
February 19, 2019 - Single CRISPR treatment can safely and stably correct genetic disease
February 19, 2019 - Multinational initiative to study familial primary distal renal tubular acidosis
February 19, 2019 - Breakthrough study highlights the promise of cell therapies for muscular dystrophy
February 19, 2019 - Subsymptom Threshold Exercise Speeds Concussion Recovery
February 19, 2019 - Midline venous catheters – infants: MedlinePlus Medical Encyclopedia
February 19, 2019 - Searching for side effects
February 19, 2019 - Humanity is all right, probably, although human extinction remains quite possible, researcher says
February 19, 2019 - Having Anesthesia Once as a Baby Does Not Cause Learning Disabilities, New Research Shows
February 19, 2019 - Anti-cancer immunotherapy could be used to fight HIV
February 19, 2019 - Customized Micropatterning for Improved Physiological Relevance
February 19, 2019 - Unique gene therapy approach paves new way to tackle rare, inherited diseases
February 19, 2019 - Activating gene that helps excite neurons reverses depression in male mice
February 19, 2019 - Science Puzzling Out Differences in Gut Bacteria Around the World
February 19, 2019 - Cells that destroy the intestine
February 19, 2019 - On recovery, vulnerability and ritual: An exhibit in white
February 19, 2019 - Scientific Duo Gets Back To Basics To Make Childbirth Safer
February 19, 2019 - COPD patients need more support when understanding new chest symptoms
February 19, 2019 - Using light-based method for production of pharmaceutical molecules
February 19, 2019 - Scientists find link between inflammation and cancer
February 19, 2019 - The High Cost Of Sex: Insurers Often Don’t Pay For Drugs To Treat Problems
February 19, 2019 - Hearing impairment associated with accelerated cognitive decline with age
February 19, 2019 - Researchers identify multiple genetic variants associated with body fat distribution
February 19, 2019 - Influenza and common cold are completely different diseases, study shows
February 19, 2019 - Scientists untangle how microbes manufacture key antibiotic compound
February 19, 2019 - Greater primary care physician supply associated with longer life spans
February 19, 2019 - HIV-1 protein suppresses immune response more broadly than thought
February 19, 2019 - Brain imaging indicates potential success of drug therapy in depressive patients
February 19, 2019 - For 2020 Dem Hopefuls, ‘Medicare-For-All’ Is A Defining Issue, However They Define It
February 19, 2019 - Specialized lung cells appear in the developing fetus much earlier than previously thought
February 19, 2019 - KU professor discusses promise of brain-computer interface to aid, restore communication
February 19, 2019 - Highly effective solution for detecting onset of aggregation in nanoparticles
February 19, 2019 - Early marker of cardiac damage triggered by cancer treatment identified
February 19, 2019 - Antidepressant drug could save people from deadly sepsis, research suggests
February 19, 2019 - CRISPR technology creates pluripotent stem cells that are ‘invisible’ to the immune system
February 19, 2019 - New study establishes how stress favors breast cancer growth and spread
February 19, 2019 - Midlife Systemic Inflammation Linked to Later Cognitive Decline
February 19, 2019 - Therapy derived from parasitic worms downregulates proinflammatory pathways
February 19, 2019 - Antimicrobial reusable coffee cups are less likely to become contaminated with bacteria, study shows
February 19, 2019 - Harnessing the evolutionary games played by cancer cells to advance therapies
Recently diagnosed cancer patients more likely to drink alcohol and use tobacco, finds study

Recently diagnosed cancer patients more likely to drink alcohol and use tobacco, finds study

image_pdfDownload PDFimage_print

Recently diagnosed cancer survivors are more likely to drink alcohol, use tobacco, and frequent tanning beds than people in later stages of recovery, according to a research team from the Virginia Tech Carilion Research Institute and Roswell Park Comprehensive Cancer Center.

Published in an early online edition of the journal Cancer, the study describes how the same people with a recent diagnosis of cancer are less likely to be physically active, to eat vegetables, and to participate in health screenings.

“There are a number of unique factors that can complicate the future for people with cancer, such as stage of disease, their treatment status, the years since they were diagnosed,” said Warren Bickel, an author of the study and a professor at the VTCRI. “We found that, for people who are closer in time to their original diagnosis, they tend to discount the future more.”

Researchers surveyed 1,000 people who had been diagnosed at different times with a variety of cancer types at various stages. Across the board, the participants who were most recently diagnosed were more likely to make unhealthy choices, reflecting a devaluation of the future. This inability to value the future as much or more than the present is referred to as delay discounting.

The study offers insight into the decision processes underlying health behaviors of people who have uncertain futures compounded by the physical and emotional trauma cancer can cause, according to Bickel, who is also a professor of psychology in Virginia Tech’s College of Science, director of the VTCRI Addiction Recovery Research Center, and co-director of the VTCRI Center for Transformative Research on Health Behaviors.

Bickel began collaborating with Christine Sheffer, the lead investigator on the study, when they both served as faculty at the University of Arkansas for Medical Sciences. Sheffer is currently an associate professor of oncology in the Department of Health Behavior at Roswell Park, a comprehensive cancer center in Buffalo, New York.

“Among cancer survivors, healthy lifestyle behaviors are linked with improved cancer outcomes and enhanced quality of life,” Sheffer said. “But a cancer diagnosis can make people feel uncertain about the future, which can contribute to discounting the positive impact of healthy behaviors like quitting tobacco, physical activity and healthy eating.”

While this is the first time that researchers have observed people with cancer demonstrating behaviors consistent with a devalued view of the future, Bickel’s team at the VTCRI has spent years studying the phenomenon in people with substance use disorders, such as addictions to alcohol, drugs, and smoking.

They’ve also documented the behavior in other populations, including people with obesity and/or prediabetes, where people devalue the future in favor of immediate satisfactions. In other words, a person with a high rate of delay discounting values an alcoholic drink or fatty food now, more than the possibility of sobriety or better health in the future.

“This valuation process doesn’t keep to one area; it permeates a person’s life. A person with an addiction to opioids, for example, will most likely take $50 dollars now over $500 in two weeks,” Bickel said. “This person discounts the future so much that $500 in two weeks doesn’t even seem like a real option – they can’t plan that far in advance when they’re trying to navigate the present.”

The researchers saw the same kinds of health choices made by the cancer patients who were most recently diagnosed, suggesting that pervasive delay discounting of the future actually functions as a trans-disease process. The time window also suggests that this trans-disease process manifests as a result of particular life events.

“We’re seeing that within an individual with a disorder, if they discount the future a lot, this discounting is not manifested in one particular area of their life; rather, discounting becomes a part of how they approach all things,” Bickel said. “A high delay discounting rate has become a trans-risk factor that cuts across multiple behaviors.”

The identification of delay discounting rate as a risk factor across disorders suggests that it might also be a potential therapeutic target for changing multiple unhealthy behaviors, according to the researchers.

“In part, this identification of a trans-risk factor is exciting for diagnostics. Take a patient with cancer. It’s not a good health plan for them to drink, smoke, or go tanning. Their doctor could identify if they’re more likely to do those things and, if so, provide additional interventions beyond medical monitoring,” Bickel said.

He pointed to therapeutic interventions, such as non-invasive brain stimulation techniques and cognitive reframing of the context in which a decision is viewed, that show promise in decreasing delay discounting rates for people who smoke cigarettes and people who overeat.

“If all these behaviors are related to discounting in an individual, and we find a way to intervene and significantly modify this phenomenon, would the effects be specific to one behavior or broad across many behaviors?” Bickel asked. “We don’t know the answer yet, but we think that if we develop a way to make individuals value the future more, the effects would be broad.”

The most recent study extends Bickel’s work of more than 30 years beyond addiction to a new domain, and offers a new understanding of a broad range of challenging health behaviors.

“We’re building a scientific understanding of an important and poorly recognized decision process,” Bickel said. “We still have a lot of work to do. As we learn more, we’re beginning to understand that this is at least a part of the process that underlies more and more behaviors.”

Source:

https://research.vtc.vt.edu/news/2018/nov/21/parallels-how-some-cancer-survivors-and-people-add/

Tagged with:

About author

Related Articles