Breaking News
February 23, 2019 - Intensive therapy during early stages of MS leads to better long-term outcomes
February 23, 2019 - Prenatal Fluconazole Exposure Increases Neonatal Risks
February 23, 2019 - Mental Health Screening: MedlinePlus Lab Test Information
February 23, 2019 - Study suggests birth mechanics are part of the process that leads to autism
February 23, 2019 - Unhealthy diet linked to poor mental health
February 23, 2019 - Study gives a snapshot of crocodile evolution
February 23, 2019 - Research finds steep rise in self-poisonings among young people
February 23, 2019 - American Gastroenterological Association announces “AGA Future Leaders Program”
February 23, 2019 - Scientists uncover new mechanisms regulating neural stem cells
February 23, 2019 - Combinations of certain insecticides turn out to be lethal for honeybees
February 23, 2019 - AHA News: Why Are Black Women at Higher Risk of Dying From Pregnancy Complications?
February 23, 2019 - NIMH » Anxiety Disorders
February 23, 2019 - Autistic people urgently need access to tailored mental health support
February 23, 2019 - Newly designed molecule could benefit people with Friedrich’s Ataxia
February 23, 2019 - Chinese CRISPR twins may have better cognition and memory
February 23, 2019 - Study finds new genetic clues associated with asthma in African ancestry populations
February 23, 2019 - Fetal signaling pathways may offer future opportunities to treat lung damage
February 23, 2019 - Early-stage osteoarthritis drug wins prestigious innovation award
February 23, 2019 - Researchers report positive findings with dasotraline for ADHD in children ages 6-12
February 23, 2019 - News study reanalyzes the effects of noncaloric sweeteners on gut microbiota
February 23, 2019 - New device allows scientists to reproduce blow effects on the heart in lab
February 23, 2019 - Holy herb identified as a potential treatment for Alzheimer’s disease
February 23, 2019 - New technology platform digitally counts growth factors in single cells
February 23, 2019 - Surgery and other treatments offer viable options for adult scoliosis
February 23, 2019 - Reduced antibody adaptability may make the elderly more vulnerable to influenza
February 23, 2019 - Neighborhood income, education associated with risk of disability progression in MS patients
February 23, 2019 - Endocrine Society opposes new rule that restricts access to Title X Family Planning Program
February 23, 2019 - 2019 guidelines for management of patients with atrial fibrillation
February 23, 2019 - Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation
February 23, 2019 - A just-right fix for a tiny heart
February 23, 2019 - UMass Amherst scientist explores role of citrus peel in decreasing gut inflammation
February 23, 2019 - Owlstone Medical and Shanghai Renji Hospital collaborate to initiate breath biopsy lung cancer trial
February 23, 2019 - AMSBIO’s comprehensive portfolio of knock-out cell lines and lysates
February 23, 2019 - New app reliably determines physicians’ skills in forming accurate, efficient diagnoses
February 23, 2019 - Peripheral nerve injury can trigger the onset and spread of ALS, shows study
February 23, 2019 - Researchers uncover mechanisms that prevent tooth replacement in mice
February 23, 2019 - Once-a-day capsule offers new way to reduce symptoms of chronic breathlessness
February 23, 2019 - FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Uloric (febuxostat)
February 23, 2019 - Phone-based intervention aids rheumatoid arthritis care
February 23, 2019 - Opioid epidemic makes eastern inroads and targets African-Americans
February 23, 2019 - New identified biomarker predicts patients who might benefit from HER2-targeted agents
February 23, 2019 - Study offers new insights into mechanisms of changes in erythrocytes under stress
February 23, 2019 - Antipsychotic polypharmacy may be beneficial for schizophrenia patients
February 23, 2019 - Researchers investigate how marijuana and tobacco co-use affects quit attempts by smokers
February 23, 2019 - Patients with diabetes mellitus have high risk of stable ischemic heart disease
February 23, 2019 - Transparency on healthcare prices played key role in Arizona health system’s turnaround
February 23, 2019 - A comprehensive, multinational review of peppers around the world
February 23, 2019 - Study finds modest decrease in burnout among physicians
February 23, 2019 - A simple change can drastically reduce unnecessary tests for urinary tract infections
February 23, 2019 - Deep Learning-Enhanced Device Detects Diabetic Retinopathy
February 23, 2019 - Researchers discover new binding partner for amyloid precursor protein
February 23, 2019 - Modest decrease seen in burnout among physicians, researchers say | News Center
February 23, 2019 - Transplanting bone marrow of young mice into old mice prevents cognitive decline
February 23, 2019 - Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding
February 23, 2019 - Johns Hopkins study describes cells that may help speed bone repair
February 23, 2019 - Scientists demonstrate influence of food odors on proteostasis
February 23, 2019 - Researchers unlock the secret behind reproduction of fish called ‘Mary’
February 23, 2019 - Acupuncture Could Help Ease Menopausal Symptoms
February 23, 2019 - Researchers use AI to detect early signs of Alzheimer’s
February 23, 2019 - On recovery, vulnerability and ritual: An exhibit in white | News Center
February 23, 2019 - Memory Stored in Unexpected Region of the Brain
February 23, 2019 - Several health experts worldwide gather at EUDONORGAN event
February 23, 2019 - Discovery of potent compound in native California shrub may lead to treatment for Alzheimer’s
February 22, 2019 - Researchers create new map of the brain’s own immune system
February 22, 2019 - ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses’ role in antibiotic stewardship
February 22, 2019 - UK Research and Innovation invests £200 million to create new generation of AI leaders
February 22, 2019 - Takeda collaboration to boost fight against Alzheimer’s and other neurodegenerative diseases
February 22, 2019 - Heavy drinking may change DNA, leading to increased craving for alcohol
February 22, 2019 - U.S. opioid deaths jump fourfold in 20 years; epidemic shifts to Eastern states | News Center
February 22, 2019 - 5 Questions with William Turner on Diversity in Medicine
February 22, 2019 - HHS Finalizes Rule Seeking To Expel Planned Parenthood From Family Planning Program
February 22, 2019 - Researchers uncover biochemical pathway that may help identify drugs to treat Alzheimer’s
February 22, 2019 - Biologist uses new grant to find ways to eliminate schistosomiasis
February 22, 2019 - Bag-mask ventilation to help patients breathe during intubation prevents complications
February 22, 2019 - AbbVie Announces New Drug Application Accepted for Priority Review by FDA for Upadacitinib for Treatment of Moderate to Severe Rheumatoid Arthritis
February 22, 2019 - Nature versus nurture and addiction
February 22, 2019 - New website connects researchers with data experts, resources | News Center
February 22, 2019 - Today’s Concerns About Drug Prices Echo The Past
February 22, 2019 - CT and Doppler equipment have low accuracy in detecting cerebral vasospasm and ischemia
February 22, 2019 - Study finds out similarity in function between healthy retina cell and tumor cell
Pregnant women face greater risk of having hemorrhagic stroke, reveal studies

Pregnant women face greater risk of having hemorrhagic stroke, reveal studies

image_pdfDownload PDFimage_print

Pregnant women face a much greater risk of having a fatal, but less common, type of stroke caused by bleeding into the brain, according to results of two studies presented by The University of Texas Health Science Center at Houston (UTHealth) at the International Stroke Conference 2019.

A study led by senior author Farhaan Vahidy, PhD, MBBS, MPH, found that pregnant women and those who recently gave birth were three to 10 times more likely to suffer intracerebral hemorrhage (ICH), which occurs when a blood vessel inside the brain bursts and spills blood into or around the brain. Vahidy is an associate professor of neurology at McGovern Medical School at UTHealth and director of the Population Health & Health Services Research Division at UTHealth Institute for Stroke and Cerebrovascular Disease.

“It’s important to remember that stroke is uncommon among the younger female population. Women undergo a number of physiological changes while pregnant, so we hypothesized that pregnancy would confer a higher ICH risk,” said first author and presenter Jennifer Meeks, MS, a research coordinator in the Department of Neurology at McGovern Medical School. “However, the scale of the increase was highly significant and strikingly greater than what was anticipated.”

Women with a history of other medical conditions such as high blood pressure and diabetes were found to be at a greater risk of ICH. Those who had preeclampsia or eclampsia were 10 times more likely to suffer ICH, according to the study.

Using publicly available administrative data, researchers analyzed more than 3.3 million deliveries among women in hospitals in New York, California, and Florida. The same women, age 28 on average, were followed and served as their own controls when no longer pregnant or postpartum.

“The results showed that the risk of ICH starts to increase during the third trimester and continues to rise into an extended postpartum period. Other attributes, such as race, also appeared to influence the likelihood. For instance, black women were twice as likely as white women to suffer ICH and Asian women were 1.68 times more likely,” Meeks said. “Further research is required to more precisely predict those groups of women who are at an increased risk of ICH during pregnancy so preventive measures may be taken.”

There are two types of stroke, hemorrhagic and ischemic, which occurs when a blood vessel carrying blood to the brain is blocked by a clot. Around 15 percent of all strokes are hemorrhagic, but they account for approximately 40 percent of all stroke deaths, according to the National Stroke Association.

In the second study, researchers found women with arteriovenous malformation (AVM), an abnormal tangle of blood vessels in the brain, had increased incidence of ICH from AVM rupture during pregnancy.

Results showed women with AVMs were almost 3½ times more likely to have ICH associated with pregnancy and delivery.

“Researchers have suspected that brain AVMs are more likely to bleed with pregnancy, but because they are uncommon, this connection was hard to prove. In our study, we looked at millions of women; the data confirmed this and were very compelling,” said Sunil Sheth, MD, the senior author, who is an assistant professor of vascular and interventional neurology at McGovern Medical School.

The study analyzed data from nearly 6.3 million women, age 28 on average, with first-time pregnancy in hospitals in New York and Florida. Of these patients, 1,024 (0.02 percent) had an AVM, which was linked to a 340 percent increased risk of ICH during the pregnancy period.

“An AVM is like having a little bomb in the head, which creates an explosion of blood in the brain if it ruptures. When this happens it can put the mother and baby in considerable danger,” Sheth said.

The abstract called for further research and improved methods to reduce ICH risk.

“We need to understand exactly what is happening – why do AVMs bleed in the first place and what is causing this substantially higher risk among pregnant women who have them?” Sheth said. “These findings could change the conversation of care for a very particular patient group. If we know a woman with a brain AVM is planning a pregnancy, it may be appropriate to treat the AVM before pregnancy or counsel for close monitoring during pregnancy.”

Source:

https://www.uth.edu/news/story.htm?id=5d2d8b9a-d1b4-4dc9-86fc-344378006898

Tagged with:

About author

Related Articles