Breaking News
April 18, 2019 - Podcast: KHN’s ‘What The Health?’ You Have Questions, We Have Answers
April 18, 2019 - Diabetic drug shows potential to be repurposed as heart disease treatment for non-diabetic patients
April 18, 2019 - New estimation method assesses natural variations in sex ratio at birth
April 18, 2019 - UTA scientist receives $1.17 million grant for cancer research
April 18, 2019 - Coagulation factor VIIa prevents bleeds in hemophilia animal models
April 18, 2019 - Researchers identify risk factors for severe infection after knee replacement
April 18, 2019 - Mass drug administration can offer community-level protection against malaria
April 18, 2019 - FDA’s added sugar label could have substantial health and cost-saving benefits
April 18, 2019 - Researchers identify cause of inherited metabolic disorder
April 18, 2019 - Single strip of white paint not sufficient to protect people who ride bikes
April 18, 2019 - Partner status influences link between sexual problems and self-efficacy in breast cancer survivors
April 18, 2019 - Colorectal Neoplasia Risk Up for Hodgkin Lymphoma Survivors
April 18, 2019 - Rigid spine muscular dystrophy – Genetics Home Reference
April 18, 2019 - Simple bile acid blood test could tell risk of stillbirth
April 18, 2019 - Center for Experimental Therapeutics aims to enable all steps of drug development | News Center
April 18, 2019 - Falling for telephone scams could be an early sign of dementia
April 18, 2019 - Researchers annotate key neuronal proteins in lamprey genome
April 18, 2019 - Study uncovers new biomarker for personalized cancer treatments
April 18, 2019 - Scientists enter research collaboration to find a cure for cancer
April 18, 2019 - Study to compare benefits of tai chi and mindfulness meditation on MS symptoms
April 18, 2019 - Gestational diabetes during pregnancy may increase risk of type 1 diabetes in children
April 18, 2019 - Is a New Remedy for Body Odor on the Horizon?
April 18, 2019 - Orthostatic hypotension – Genetics Home Reference
April 18, 2019 - Healing the heartbreak of stillbirth and newborn death
April 18, 2019 - Conference to highlight advances in human immune monitoring, bioinformatics | News Center
April 18, 2019 - Bacteria use viruses for self-recognition, study reveals
April 18, 2019 - New adhesive patch could help reduce post-heart attack muscle damage
April 18, 2019 - Researchers analyze the effects of dark play in a serious video game
April 18, 2019 - Filial cannibalism and offspring abandonment may be forms of parental care
April 18, 2019 - Two proteins act in concert to maintain a healthy heart in mice, shows study
April 18, 2019 - Scientists create a functioning 3D printed heart
April 18, 2019 - Non-invasive vagus nerve stimulation improves disease symptoms in patients with rheumatoid arthritis
April 18, 2019 - Majority of men struggle to understand diagnosis and treatment of prostate cancer
April 18, 2019 - Researchers create new small molecules that may combat equine encephalitis viruses
April 18, 2019 - Animal-assisted therapy improves social behavior in patients with brain injuries
April 18, 2019 - Some viruses help protect harmful bacteria in CF patients | News Center
April 18, 2019 - Outpatient healthcare providers inappropriately prescribe antibiotics to 40% of patients
April 18, 2019 - Men who have a resting heart rate of 75 bpm are twice as likely to die early
April 18, 2019 - Novel serum biomarkers to detect NAFLD-related fibrosis
April 18, 2019 - New study delves deeper into individual genomic differences than ever before
April 18, 2019 - Gilead and Galapagos Announce Filgotinib Meets Primary Endpoint in the Phase 3 FINCH 3 Study in Methotrexate-Naïve Rheumatoid Arthritis Patients
April 18, 2019 - Emotional mirror neurons found in rats
April 18, 2019 - Sylvia Plevritis appointed chair of biomedical data science | News Center
April 18, 2019 - Yeast strain provides manufacturing boost to low-calorie sweetener derived from lactose
April 18, 2019 - One in five children and youth suffer from a mental disorder
April 18, 2019 - Improper inhaler use common in children with asthma
April 18, 2019 - C-Path and CDISC release global Therapeutic Area Standard for HIV research
April 18, 2019 - Integrating AI to analyze imaging data allows early recognition of heart disease
April 18, 2019 - Low-cost, high-speed algorithm may allow animal-free chemical toxicity testing
April 18, 2019 - HPV-negative cervical cancers are more aggressive with worse prognosis
April 18, 2019 - AI detects prostate cancer with same level of accuracy as experienced radiologists
April 18, 2019 - Study resolves sex differences in psychiatric illness risk
April 18, 2019 - Novartis Announces FDA Filing Acceptance and Priority Review of Brolucizumab (RTH258) for Patients with Wet AMD
April 18, 2019 - Cocktail of common antibiotics can fight resistant E. coli
April 18, 2019 - Persis Drell to give keynote address at medical school diploma ceremony | News Center
April 18, 2019 - EpicTogether: Remembering Our Why
April 18, 2019 - Study identifies novel loci contributing to asthma susceptibility in adults
April 18, 2019 - Gut bacteria and pregnancy
April 18, 2019 - New study finds that screening could help prevent rare types of cervical cancer
April 17, 2019 - Spatial orgnization of the genome can be altered using small molecules
April 17, 2019 - AEDs Tied to Higher Pneumonia Risk in Alzheimer Patients
April 17, 2019 - Telemedicine tied to more antibiotics for kids, study finds
April 17, 2019 - Two medical students awarded 2019 Soros Fellowships for New Americans | News Center
April 17, 2019 - Sociologist Constance A. Nathanson Awarded Guggenheim Fellowship
April 17, 2019 - Empathy and hormones could account for aggressive behavior in children, shows study
April 17, 2019 - Researchers develop oral appliance to help sufferers of sleep apnea
April 17, 2019 - Neuronal transport factor detects its target transcripts in more complex manner than previously thought
April 17, 2019 - New drug-delivery system senses high oxidant levels, responds to body chemistry and environment
April 17, 2019 - Health Tip: Horseback Trail Riding Safety
April 17, 2019 - Scientists outline the promises and pitfalls of machine learning in medicine
April 17, 2019 - $12 million grant renewal for flu vaccine research | News Center
April 17, 2019 - Lisa Kachnic, MD, Joins Columbia University as Chair of Radiation Oncology
April 17, 2019 - New study sheds light on how extreme temperature hampers spermatogenesis in insects
April 17, 2019 - Study tests high-tech, non-pharmaceutical way to address ADHD and distractibility
April 17, 2019 - New EZ-2 evaporator for clinical biochemistry sample preparation
April 17, 2019 - Fat shaming celebrities may make women more judgemental about being overweight
April 17, 2019 - Magic mouthwash effectively reduces mouth sore pain caused by radiation therapy
April 17, 2019 - CBD could help slip medications into the brain
April 17, 2019 - Scientists characterize 2017 pneumonic plague outbreak in Madagascar
April 17, 2019 - Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature
Bruker showcases new analytical systems and applied market solutions at Pittcon 2019

Bruker showcases new analytical systems and applied market solutions at Pittcon 2019

image_pdfDownload PDFimage_print

At Pittcon 2019, Bruker this week highlights new and innovative analytical systems and high-value applied market solutions for food analysis, pharma applications, materials science research and quality control, clinical and preclinical research, and advances in scientific software solutions.

Frank H. Laukien, Ph.D., Bruker’s President and CEO, commented:

Our new analytical instruments and solutions shown at Pittcon 2019 demonstrate the diversity and flexibility that Bruker brings to the world of laboratory science. Bruker is committed to providing the best technological solutions to meet the analytical requirements of our customers, and that includes increasing our presence in the laboratory software and applied solutions markets.”

Applied and Industrial R&D and QC

The novel INVENIO-S FTIR system is the entry-level version of the flexible and innovative INVENIO® platform, replacing the very successful TENSOR FTIR series. The INVENIO-S is a new, high-performance FTIR spectrometer focused on maximum productivity in advanced laboratory analysis and research. Bruker’s permanently aligned RockSolidTM interferometer, CenterGlowTM IR source, temperature controlled DTGS, and the long-life diode laser together ensure best performance, robustness and low running costs. The integrated touch panel operation provides intuitive guidance with typical workflows from routine analytical QC protocols to R&D applications.

The new G6 LEONARDOTM is an economic, robust and precise inert gas fusion (IGF) analyzer for oxygen, nitrogen and hydrogen (ONH) concentration measurements in inorganic samples. The G6 LEONARDO introduces SampleCare™ into IGF-analysis for metals and ceramics, and deploys the Smart Molecule SequenceTM for elemental analysis. With its pre-calibrated standard methods and argon gas instead of helium, the G6 LEONARDO addresses the needs of industrial process and QC for easy and cost-effective operation.

Laboratory Software and Solutions for Pharma

Bruker announced that it has acquired Arxspan LLC, a provider of cloud-based scientific software and workflow solutions. Arxspan is known for its line of cloud-based products for the management of research data, with a focus on serving pharmaceutical and biopharma customers. Bruker can now provide a range of software tools for customers in the chemistry, pharmaceutical, biopharma and analytical laboratory markets. Together with the Mestrelab strategic partnership and majority investment, the acquisition of Arxspan will allow Bruker to offer state-of-the-art chemistry and biopharma software tools, supporting discovery and development.

Bruker and Mestrelab Expand Software Solutions Portfolio for applied NMR: The laboratory of tomorrow requires the integration of multiple technology platforms. The strategic collaboration of Mestrelab and Bruker is expected to provide a simple, instrument-to-result automation environment that allows users to build automated solutions tailored to their workflow. An example is the integration of Bruker’s Fragment-Based Screening (FBS) solution with Mestrelab’s MScreen software, which provides drug discovery groups with an integrated experience from data acquisition and data analysis to the identification of hits in FBS-by-NMR campaigns.

Bruker also announces minispec Form Check, a reliable and affordable TD-NMR (Time-Domain Nuclear Magnetic Resonance) solution to monitor phase purity and quantify physical API (Active Pharmaceutical Ingredient) forms including amorphization. The patent pending minispec Form Check uses 1H or 19F relaxometry data as easy-to-obtain fingerprints for expected components in solid mixtures, replacing excessive calibration, delicate sample preparation and expert know-how. In the pharma industry, API form characterization and quantification are important from drug development and formulation to manufacturing, where it is important to understand how solid API forms are influenced by production and storage.

Quantitative Performance Qualification (qPQ) for Quantitative NMR (qNMR) Applications: A collaboration between Bruker and MilliporeSigma has led to the development of certified reference materials (CRM) tailored to qNMR. A novel, two-component mixture manufactured in the ISO/IEC 17025 and ISO 17034 accreditated workflow at MilliporeSigma is the basis of the new qPQ test. This qPQ is now incorporated within the Bruker AssureSST™ software, allowing automated PQ tailored to qNMR.

Food Analysis Solutions

Bruker announced the launch of the MIRA milk analyzer based on infrared technology, as well as the GLOBULYSER for analyzing the homogenizer efficiency of raw milk and liquid milk products. The MIRA features ease-of-use in a high precision analyzer with IR technology. MIRA is a robust, cost-effective solution for QC of raw milk, processed or standardized milk, whey and cream. The GLOBULYSER has been developed in cooperation with the dairy industry to create an easy-to-use analyzer for mean fat globule size in milk, liquid milk products, and in dissolved milk powders.

The new, proprietary Honey-Profiling 2.0 Method for the Bruker NMR FoodScreener® platform now further improves the detection of sugar syrups, and considerably expands the scope of geographical and botanical honey origins that can be verified, including the popular manuka honey which is subject to frequent fraud due to its high value. The expanded 2.0 method was developed in collaboration with partners QSI and Alnumed, and features a reference database containing over 18,000 honey samples, 50 geographical origins and 100 botanical varieties. With Honey-Profiling 2.0, a comprehensive analysis of authenticity and quality is performed under automation in 25 minutes.

Clinical Phenomics and Proteomics

Bruker and Murdoch University have announced a collaboration for a phenomics center of excellence in Australia to further develop NMR and MS-based Precision Medicine Solutions. Murdoch University (www.murdoch.edu.au), the Australian National Phenome Center (ANPC, a core platform of the Western Australian Health Translation Network) and Bruker announced a memorandum of understanding for a metabolomics research and instrumentation infrastructure collaboration to develop the world’s premier phenomics center for the advancement of precision medicine.

Jeremy Nicholson, Ph.D., ProVice Chancellor of Health Sciences at Murdoch University and leading the APCN, commented:

This collaboration brings state-of-the-art instruments and experienced professionals to Australia, augmenting the growing investment in precision medicine in the Asia Pacific region. Working with Bruker the ANPC at Murdoch aspire to create new disease prevention and treatment strategies through integrative studies of humans in their total environment. This will enable better understanding of gene- environment interactions that determine health status of individuals and populations. We wish to leverage key technology advantages offered by Bruker platforms and address new challenges that link precision nutrition and health programs to large scale food screening and population phenotyping. Such precise data will allow clinicians to better predict health problems and intervene earlier, saving time, money and lives. The potential of this research to provide truly personalized care is remarkable.”

Microscopy, Preclinical Imaging and Nanoanalysis

The new SKYSCANTM 1273 3D X-ray microscope (XRM) sets a new standard for high-resolution non-destructive testing (NDT) with benchtop microCT systems with performance previously only achieved by floor standing systems. Samples with up to 20 kg weight and up to 500 mm length and 300 mm diameter can be investigated. The combination of an innovative X-ray source running at higher power settings and a 6-megapixel flat-panel detector with high sensitivity and speed provides excellent image quality in seconds. Areas of application range from manufacturing, geology, oil and gas exploration to bone imaging.

Bruker announces an order from the Champalimaud Foundation in Portgual for the world’s first, preclinical BioSpec® 18 Tesla ultra-high field magnetic resonance imaging (MRI) system for delivery in 2021. The ultra-high magnetic field and sensitivity-enhancing CryoProbes will be used to develop novel contrasts in MRI and MR spectroscopic imaging. These new methods will be applied to investigate cancer, metastasis and premetastatic niches in vivo in multiple animal models of cancer; as well as for advanced neuroscience research on mouse brain plasticity and activity. The novel MRI system will enable truly microscopic 3D spatial resolution in vivo, allowing very detailed morphology investigations.

The JPK NanoWizard® ULTRA Speed 2 combines high speed and resolution AFM with advanced bio-imaging features. Developed in close collaboration with bio-AFM customers, the system is the first new product to come out of Bruker’s JPK BioAFM business, formed in July 2018 with the acquisition of JPK Instruments AG. With an AFM scanning speed of 10 frames per second, true atomic resolution and advanced life-science capabilities, it raises the bar in technical performance for correlative microscopy applications.

The new Dimension XR™ family of scanning probe microscopes incorporate major AFM innovations, including Bruker’s proprietary and exclusive DataCube nanoelectrical modes, AFM-SECM for energy research, and the new AFM-nDMA mode, which for the first time correlates polymer nanomechanics to bulk dynamic mechanical analysis (DMA). Dimension XR is available in three configurations optimized for nanomechanics, nanoelectrical or nanoelectrochemical applications. These systems significantly expand researchers’ ability to quantify material properties at the nanoscale in air, fluids, electrical and chemically reactive environments.

Source:

https://www.bruker.com/news/bruker-highlights-new-systems-and-applied-market-solutions-at-pittcon.html

Tagged with:

About author

Related Articles