Breaking News
May 3, 2019 - Vaping and Smoking May Signal Greater Motivation to Quit
May 3, 2019 - Dementia looks different in brains of Hispanics
May 3, 2019 - Short-Staffed Nursing Homes See Drop In Medicare Ratings
May 3, 2019 - Study of teens with eating disorders explores how substance users differ from non-substance users
May 3, 2019 - Scientists develop new video game that may help in the study of Alzheimer’s
May 3, 2019 - Arc Bio introduces Galileo Pathogen Solution product line at ASM Clinical Virology Symposium
May 3, 2019 - Cornell University study uncovers relationship between starch digestion gene and gut bacteria
May 3, 2019 - How to Safely Use Glucose Meters and Test Strips for Diabetes
May 3, 2019 - Anti-inflammatory drugs ineffective for prevention of Alzheimer’s disease
May 3, 2019 - Study tracks Pennsylvania’s oil and gas waste-disposal practices
May 3, 2019 - Creating a better radiation diagnostic test for astronauts
May 3, 2019 - Vegans are often deficient in these four nutrients
May 3, 2019 - PPDC announces seed grants to develop medical devices for children
May 3, 2019 - Study maps out the frequency and impact of water polo head injuries
May 3, 2019 - Research on Reddit identifies risks associated with unproven treatments for opioid addiction
May 3, 2019 - Good smells may help ease tobacco cravings
May 3, 2019 - Medical financial hardship found to be very common among people in the United States
May 3, 2019 - Researchers develop multimodal system for personalized post-stroke rehabilitation
May 3, 2019 - Study shows significant mortality benefit with CABG over percutaneous coronary intervention
May 3, 2019 - Will gene-editing of human embryos ever be justifiable?
May 3, 2019 - FDA Approves Dengvaxia (dengue vaccine) for the Prevention of Dengue Disease in Endemic Regions
May 3, 2019 - Why Tonsillitis Keeps Coming Back
May 3, 2019 - Fighting the opioid epidemic with data
May 3, 2019 - Maggot sausages may soon be a reality
May 3, 2019 - Deletion of ATDC gene prevents development of pancreatic cancer in mice
May 2, 2019 - Targeted Therapy Promising for Rare Hematologic Cancer
May 2, 2019 - Alzheimer’s disease is a ‘double-prion disorder,’ study shows
May 2, 2019 - Reservoir bugs: How one bacterial menace makes its home in the human stomach
May 2, 2019 - Clinical, Admin Staff From Cardiology Get Sneak Peek at Epic
May 2, 2019 - Depression increases hospital use and mortality in children
May 2, 2019 - Vicon and NOC support CURE International to create first gait lab in Ethiopia
May 2, 2019 - Researchers use 3D printer to make paper organs
May 2, 2019 - Viral infection in utero associated with behavioral abnormalities in offspring
May 2, 2019 - U.S. Teen Opioid Deaths Soaring
May 2, 2019 - Opioid distribution data should be public
May 2, 2019 - In the Spotlight: “I’m learning every single day”
May 2, 2019 - 2019 Schaefer Scholars Announced
May 2, 2019 - Podcast: KHN’s ‘What The Health?’ Bye-Bye, ACA, And Hello ‘Medicare-For-All’?
May 2, 2019 - Study describes new viral molecular evasion mechanism used by cytomegalovirus
May 2, 2019 - SLU study suggests a more equitable way for Medicare reimbursement
May 2, 2019 - Scientists discover first gene involved in lower urinary tract obstruction
May 2, 2019 - Researchers identify 34 genes associated with increased risk of ovarian cancer
May 2, 2019 - Many low-income infants receive formula in the first few days of life, finds study
May 2, 2019 - Global study finds high success rate for hip and knee replacements
May 2, 2019 - Taking depression seriously: What is it?
May 2, 2019 - With Head Injuries Mounting, Will Cities Put Their Feet Down On E-Scooters?
May 2, 2019 - Scientists develop small fluorophores for tracking metabolites in living cells
May 2, 2019 - Study casts new light into how mothers’ and babies’ genes influence birth weight
May 2, 2019 - Researchers uncover new brain mechanisms regulating body weight
May 2, 2019 - Organ-on-chip systems offered to Asia-Pacific regions by Sydney’s AXT
May 2, 2019 - Adoption of new rules drops readmission penalties against safety net hospitals
May 2, 2019 - Kids and teens who consume zero-calorie sweetened beverages do not save calories
May 2, 2019 - Improved procedure for cancer-related erectile dysfunction
May 2, 2019 - Hormone may improve social behavior in autism
May 2, 2019 - Alzheimer’s disease may be caused by infectious proteins called prions
May 2, 2019 - Even Doctors Can’t Navigate Our ‘Broken Health Care System’
May 2, 2019 - Study looks at the impact on criminal persistence of head injuries
May 2, 2019 - Honey ‘as high in sugars as table sugar’
May 2, 2019 - Innovations to U.S. food system could help consumers in choosing healthy foods
May 2, 2019 - FDA Approves Mavyret (glecaprevir and pibrentasvir) as First Treatment for All Genotypes of Hepatitis C in Pediatric Patients
May 2, 2019 - Women underreport prevalence and intensity of their own snoring
May 2, 2019 - Concussion summit focuses on science behind brain injury
May 2, 2019 - Booker’s Argument For Environmental Justice Stays Within The Lines
May 2, 2019 - Cornell research explains increased metastatic cancer risk in diabetics
May 2, 2019 - Mount Sinai study provides fresh insights into cellular pathways that cause cancer
May 2, 2019 - Researchers to study link between prenatal pesticide exposures and childhood ADHD
May 2, 2019 - CoGEN Congress 2019: Speakers’ overviews
May 2, 2019 - A new strategy for managing diabetic macular edema in people with good vision
May 2, 2019 - Sagent Pharmaceuticals Issues Voluntary Nationwide Recall of Ketorolac Tromethamine Injection, USP, 60mg/2mL (30mg per mL) Due to Lack of Sterility Assurance
May 2, 2019 - Screen time associated with behavioral problems in preschoolers
May 2, 2019 - Hormone reduces social impairment in kids with autism | News Center
May 2, 2019 - Researchers synthesize peroxidase-mimicking nanozyme with low cost and superior catalytic activity
May 2, 2019 - Study results of a potential drug to treat Type 2 diabetes in children announced
May 2, 2019 - Multigene test helps doctors to make effective treatment decisions for breast cancer patients
May 2, 2019 - UNC School of Medicine initiative providing unique care to dementia patients
May 2, 2019 - Nestlé Health Science and VHP join forces to launch innovative COPES program for cancer patients
May 2, 2019 - Study examines how our brain generates consciousness and loses it during anesthesia
May 2, 2019 - Transition Support Program May Aid Young Adults With Type 1 Diabetes
May 2, 2019 - Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death
May 2, 2019 - Research reveals complexity of how we make decisions
Butler Hospital receives COBRE grant to enhance research on neuropsychiatric illnesses

Butler Hospital receives COBRE grant to enhance research on neuropsychiatric illnesses

Neuropsychiatric illnesses are common and highly impairing conditions that arise from abnormal functioning of the brain. These conditions – impulsivity, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder (OCD) among others – can greatly impair the health of those affected by them and impact their ability to learn, work, and emotionally cope.

With a focus on enhancing research to shed light on these disorders and their potential future health implications, Butler Hospital has been awarded a $12 million, five-year Center of Biomedical Research Excellence (COBRE) grant from the National Institute of General Medical Sciences, part of the National Institutes of Health (NIH). This creates key infrastructure and support a core group of interdisciplinary investigators to build a self-sustaining center of excellence in clinical-translational brain research. The overall goal of The COBRE Center for Neuromodulation (CCN) at Butler Hospital will be to address the pressing need for novel treatments for people struggling with neuropsychiatric disease, by understanding and testing methods to change the functioning of brain circuits underlying such illnesses.

“This grant establishes Butler Hospital and The COBRE Center for Neuromodulation as a national leader in this field of translational medicine, expanding both research and clinical application of non-invasive brain stimulation across disorders of brain and behavior,” said Benjamin Greenberg MD PhD, principal investigator on the grant, director of the OCD Research Program at Butler Hospital, and professor of Psychiatry and Human Behavior at The Warren Alpert Medical School of Brown University. “It will unify an interdisciplinary community in clinical-translational research on neuropsychiatric illnesses such as impulsivity, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder (OCD), all focused on ultimately helping patients by developing new treatments.”

“This new NIH COBRE grant will advance understanding of neuropsychiatric conditions such as post-traumatic stress disorder and lead to research breakthroughs in mental and behavioral health,” said Senator Jack Reed, a member of the Appropriations Committee who noted that this federal grant compliments a $12 million COBRE grant for Brown University’s Center for Central Nervous System Function, part of the Carney Institute for Brain Science, that was awarded in December. “This federal funding will also help boost the state’s growing biomedical research and innovation capacity, helping to bolster mentorship, advance the careers of young researchers, and support numerous jobs in the biomedical research industry.”

“There is so much we still don’t know about managing relatively common conditions like post-traumatic stress disorder and obsessive-compulsive disorder,” said U.S. Senator Sheldon Whitehouse. “With this federal funding, Butler Hospital will lead pioneering brain science research to help patients whose lives are deeply affected by these conditions.”

“With this new federal funding, Butler Hospital will continue to enhance its life-changing research to help people suffering from neuropsychiatric conditions,” said Congressman James Langevin. “I congratulate Butler Hospital for winning this competitive award, and I will continue to fight for increased investment to support important biomedical research.”

“As Rhode Island’s oldest psychiatric hospital, Butler Hospital has always been a leader in treating and researching psychiatric illnesses and substance abuse. The awarding of this $12 million COBRE grant will allow the hospital to expand its critical work to include helping people throughout our state and New England who suffer from neuropsychiatric conditions,” said Congressman David N. Cicilline. “The many achievements of Butler Hospital and top mental hospitals around the country highlight the importance of fully funding the NIH’s many vital programs, and I’m proud of the work that our Congressional Delegation has done to make sure we can continue to create opportunities to bring valuable federal funds home to Rhode Island.”

Importantly, The COBRE Center for Neuromodulation will nurture the careers of exceptional young researchers in Rhode Island by providing them the infrastructure and expertise to administer brain stimulation and assess its effects on both the brain and behavior. The CCN, co-directed by Linda Carpenter, MD, a nationally recognized leader in brain stimulation therapies and research based at Butler Hospital, will provide the platform these exceptional Project Leaders and other early-career researchers need to make important discoveries and transform them into better treatments for patients with neuropsychiatric illnesses. The stimulation methods to be tested are noninvasive, meaning they affect the brain when applied on the scalp (transcranial magnetic and transcranial electrical stimulation); stimulation effects will be assessed with neuroimaging (MRI) and other methods.

The first group of Project Leaders supported by the COBRE CCN will focus on impulsive behavior (a problem across multiple illnesses), PTSD, and obsessive-compulsive disorder (OCD). They will be supported in several critical ways, including in research administration and logistics, by experienced, highly skilled mentors and by new research infrastructure to aid them in the design and analysis of experiments and the practical use of stimulation and neuroimaging methods. This, plus a pilot grant program, will advance the careers of talented young researchers in Rhode Island towards making important independent contributions to science and health.


Tagged with:

About author

Related Articles