HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system’s response to infection than previously thought. Their findings could help inform more effective treatment strategies for HIV, including those aimed at activating the dormant virus in patients before subsequently eliminating it. […]Continue Reading ...
Scanning electromicrograph of an HIV-infected T cell. Credit: NIAID Researchers can now quickly and accurately count a hidden, inactive form of the human immunodeficiency virus (HIV) that lurks in patients’ cells. This version of HIV embeds into cells’ genomes and can persist despite otherwise successful therapies—thwarting attempts to cure the infection. Using a new genetic […]Continue Reading ...
Credit: stock.adobe.com Much of the research on HIV has focused on preventing infection but little is understood about how the body keeps the virus in check post-infection. A new study by Yale investigators reveals the role of a protein that serves to block HIV gene expression once it has entered human cells. The research team, […]Continue Reading ...
Members of the research team (right to left): Bioengineering seniors Erin Tevonian and Melina Megaridis, Post-doctoral fellow Kathrin Bohn-Wippert, Bioengineering graduate students Meng-Yao Huang and Yiyang Lu, and Professor Roy Dar. Credit: University of Illinois Department of Bioengineering. Thanks to the development of antiretroviral drugs, human immunodeficiency virus (HIV) is considered a manageable chronic disease […]Continue Reading ...
HIV infecting a human cell. Credit: NIH For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human primates. The new study shows that rhesus macaque monkeys can be prompted to […]Continue Reading ...
Credit: CC0 Public Domain HIV evades the body’s immune defenses through a multitude of mutations, and antibodies produced by the host’s immune system to fight HIV also follow convoluted evolutionary pathways that have been challenging to track. This complexity has made it difficult for researchers to develop a preventive HIV vaccine that elicits effective antibodies […]Continue Reading ...
HIV infecting a human cell. Credit: NIH A new study suggests that a genetic switch that causes latent HIV inside cells to begin to replicate can be manipulated to completely eradicate the virus from the human body. Cells harboring latent HIV are “invisible” to the natural defenses of the immune system. The findings, which suggest […]Continue Reading ...
Credit: CC0 Public Domain Of the 40 million people around the world infected with HIV, less than one per cent have immune systems strong enough to suppress the virus for extended periods of time. These special immune systems are known as “elite controllers.” But how do they actually fight HIV? Canadian scientists think they’ve found […]Continue Reading ...
Mice expressing the lectin CD169 capture incoming retroviruses and reduce their systemic dissemination. In contrast, in mice lacking CD169, spread of blood cancer causing retrovirus is enhanced, resulting in heightened infection (green) in the spleen. Credit: Yale University Taking aim at a promising molecular target can combat the spread of retroviruses that can cause blood […]Continue Reading ...
Credit: CC0 Public Domain HIV viral suppression is a positive medical outcome which indicates viral control and inability to transmit infection. It is usually achieved through antiretroviral therapy. There is a lack of research into the psychosocial factors affecting HIV viral suppression, such as perceived neighborhood social cohesion, or how connected the subject feels to […]Continue Reading ...
Young black men who have sex with men (MSM) are 16 times more likely to have an HIV infection than their white peers despite more frequent testing for HIV and being less likely to have unsafe sex, reports a new Northwestern Medicine study. The study was recently published in the Journal of Acquired Immunodeficiency Syndromes. […]Continue Reading ...
Credit: CC0 Public Domain As Australia marks World AIDS Day on Saturday 1 December, new research reveals the enduring challenge of tackling stigma surrounding HIV. The Stigma Indicators Monitoring Project: People Living with HIV, by the UNSW Sydney Centre for Social Research in Health (CSRH), is jointly released today with The Australian Federation of AIDS […]Continue Reading ...
HIVSmart! is available for smartphone, tablet or web-based (Android, iPhone, and iPad) confidential software app that was developed by Dr. Pant Pai and her team at the RI-MUHC. It informs, interprets and stores data confidentially but, most importantly, it links users to counselling or care quickly and encourages the user to stay in care. Credit: […]Continue Reading ...
Navy Petty Officer 1st Class Oliver Arceo draws blood from a sailor for routine HIV testing. Credit: US Navy photo by Petty Officer 1st Class Marie Montez A new commentary from National Institutes of Health scientists asserts that engaging men in HIV prevention and care is essential to the goal of ending the HIV pandemic. […]Continue Reading ...
The WHO recommends testing for HIV every 6 to 12 months. Credit: Shutterstock There was a time when HIV was untreatable, heavily stigmatised, and the benefits of testing weren’t as clear as they are now. But that was 25 years ago. HIV testing remains the crucial entry point for all HIV services, including both prevention […]Continue Reading ...
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