Venous thromboembolism, encompassing blood clots in leg veins or clots that travel to the lungs, is the most common cause of preventable death in hospital settings. While these clots can be prevented by VTE prophylaxis, which reduces mortality by as much as 80 percent, it is not universally prescribed for high-risk patients. Researchers found that […]Continue Reading ...
PAD4 has been observed in cancers but its role was unclear. An Oxford University team have found that PAD4 citrullinates protein E2F-1, which causes it to form a protein complex with BRD4 that drives expression of inflammatory genes.Continue Reading ...
Many double-stranded DNA viruses infect cells by ejecting their genetic information into a host cell. But how does the rigid DNA packaged inside a virus flow into a cell? A biophysicist has shown that in viruses that infect both bacteria and humans, a phase transition at the temperature of infection allows the DNA to change […]Continue Reading ...
Scientists have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair.Continue Reading ...
It is well known that following a healthy lifestyle — not smoking, avoiding excess weight and getting regular exercise — can reduce the risk of heart disease. But what about people who have inherited gene variants known to increase risk? A study has found that, even among those at high genetic risk, following a healthy […]Continue Reading ...
High indoor temperatures appear to worsen symptoms of chronic obstructive pulmonary disease, or COPD, particularly in homes that also have high levels of air pollutants, according to new research.Continue Reading ...
Researchers have measured a biomarker in cell-free blood plasma which can be linked to an overactive stress system in suicidal individuals. This biomarker can hopefully be used in future psychiatric studies.Continue Reading ...
Playing \’brain-training\’ video games may help improve some cognitive abilities of people with multiple sclerosis by strengthening neural connections in an important part of their brains, according to a new study.Continue Reading ...
African-American dialysis patients with sickle cell trait received about 13% more of the medications used to treat anemia than other African-American patients to reach the same level of hemoglobin. The sickle cell trait was slightly more common in African-American patients on dialysis (10%) than in the general African-American population (6.5% to 8.7%).Continue Reading ...
Researchers have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).Continue Reading ...
The antibody VRC01 proves safe for individuals infected with HIV-1, but only modestly controls the virus in participants who stop receiving antiretroviral therapy, report scientists.Continue Reading ...
Children with congenital heart disease and ADHD can take stimulant medications without fear of significant cardiovascular side effects, a new study concludes.Continue Reading ...
Slightly more than 10% of all patients who undergo successful surgery for prostate cancer have an elevated risk of tumor recurrence afterwards – especially as metastases. Under the microscope, it is possible to identify invasion of the tumor into the lymph and blood vessels, this being the tumor behavior responsible for the formation of metastases, […]Continue Reading ...
A new breakthrough combination treatment has been developed that utilizes a vaccine to activate an immune response against advanced brain tumors.Continue Reading ...
Like exploring the inner workings of a clock, researchers are digging into the inner workings of the tiny cellular machines called spliceosomes, which help make all of the proteins our bodies need to function. They have now captured images of this machine, revealing details never seen before.Continue Reading ...
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