An enzyme called SIRT1 declines in the blood vessels with age and restoring it reverses the effects of vascular aging. After receiving a supplement called NMN, older mice showed increased capillary density, blood flow, mobility, and endurance. Credit: Cell; Zolt Arany, Perelman School of Medicine, University of Pennsylvania As people age, their blood-vessel density and […]Continue Reading ...
Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur. Replacing host bone marrow is the best strategy for preventing relapse but […]Continue Reading ...
Microscope picture of the microfluidic device developed by Manoj Sharma. The horizontal stripe is the microchannel, which measures 0.2 mm across. The six other stripes are optic fibers that capture the fluourescent light and lead it to a spectrometer. The fifteen dots in the middle are micropillars. Credit: Eindhoven University of Technology Researchers from TU […]Continue Reading ...
Associate Professor Elizabeth Broadbent with an iRobi robot. Credit: University of Auckland A pilot randomised controlled trial using robots to help people at home with Chronic Obstructive Pulmonary Disease has found that the robots helped patients take their medication, carry out exercises, and keep them company. The study, “Using robots at home to support patients […]Continue Reading ...
Stem cell-derived retinal pigmented epithelial cells. Cell borders are green and nuclei are red. Credit: University of California – Santa Barbara In July 2015, 86-year-old Douglas Waters developed severe age-related macular degeneration (AMD). He struggled to see things clearly, even when up close. A few months later, he became part of a clinical trial that […]Continue Reading ...
A method currently used by thousands of laboratories across the nation to preserve tissue could render samples useless over time for a common test to assess gene activity. Credit: iStock A method currently used by thousands of laboratories across the country to preserve tissue could render samples useless over time for a common test to […]Continue Reading ...
NTU Singapore scientists found that collagen (in right petri dish) processed from snakehead fish scales has potential for biomedical applications. Credit: NTU Singapore Scientists from Nanyang Technological University, Singapore (NTU Singapore) have established that collagen derived from fish scales could be effective for various biomedical applications such as wound healing. Commonly removed before cooking, the […]Continue Reading ...
Mouse (left) and human (right) alveolar progenitor cells grow into large lung organoids in culture, and make multiple types of epithelial cells including gas exchange type 1 cells (red) and surfactant-producing type 2 cells (green). Credit: The lab of Ed Morrisey, Perelman School of Medicine, University of Pennsylvania. Researchers have identified a lung stem cell […]Continue Reading ...
Microglia in a healthy adult mouse retina. Credit: Wai T. Wong, National Eye Institute Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute (NEI). The cells also re-establish their normal organization and function. The findings […]Continue Reading ...
After a drop of blood is placed into the central chamber of this microfluidic device, neutrophils can enter the mazes of channels on each side, while red blood cells and other components are retained in the chamber. Patterns of neutrophil migration within the channels can distinguish between patients with and without sepsis. Credit: Felix Ellett, […]Continue Reading ...
Human skin structure. Credit: Wikipedia Ever notice how a cut inside the mouth heals much faster than a cut to the skin? Gum tissue repairs itself roughly twice as fast as skin and with reduced scar formation. One reason might be because of the characteristics of gingival mesenchymal stem cells, or GMSCs, which can give […]Continue Reading ...
Credit: National Cancer Institute Researchers from Cardiff University have created the world’s first synthetic, non-biologic vaccine. The non-biologic influenza vaccine, which can be delivered orally, could herald a revolution in vaccine delivery. Stable at room temperature, the new type of vaccine, which could be given in pill form, does not require refrigeration – a process that can account for most of the cost of delivery […]Continue Reading ...
Cells with Huntington’s disease lack the enzyme that creates cysteine and die in environments without it (Left). Cells treated with monensin have cysteine stores and are better prepared to survive in environments with little cysteine (Right). Credit: Juan Sbodio Working with cells grown in the lab, Johns Hopkins researchers have identified a biochemical pathway that […]Continue Reading ...
One of the greatest health threats to children with sickle cell anemia is getting a dangerous bacterial infection—but most are not receiving a key medication to reduce the risk, a new study suggests. Just 18 percent of children with the inherited blood disease in the Michigan Medicine study received daily antibiotics—which are proven to reduce […]Continue Reading ...
Using the Mosquito Brain Browser at mosquitobrains.org, users can select and view distinct regions (different colors) of the female Aedes aegypti brain. Credit: Meg Younger and Nick Didkovsky A mosquito’s head is about the size of a pencil tip, but it packs a dangerous punch: it is the delivery system for malaria, yellow fever, and […]Continue Reading ...
- Detecting diminished dopamine-firing cells inside brain could reveal earliest signs of Alzheimer’s
- Case study shows how intravascular ultrasound imaging helps detect acute aortic syndrome
- Research reveals new mechanism by which HIV evades the immune system
- Nanodisc-delivered cancer treatment helps eliminate tumors
- Functional connectivity MRI could help detect brain disorders and diseases
- Finding better way to quantify neuropathy symptoms and treatment efficacy
- Study examines effectiveness of caregiver education about sickle cell trait
- High-resolution images of tumor vasculature using new technology
- Lack of sleep may be linked to risk factor for Alzheimer’s disease
- Study finds neurotransmitter may play a role in alcohol relapse, addiction
- Researchers build molecular networks of calcific aortic valve disease
- Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens
- Scientists decipher mechanism of chemotherapy induced female infertility
- New insight may allow researchers to design drugs that improve immune responses to vaccines
- FDA Approves Crysvita (burosumab-twza) for X-Linked Hypophosphatemia
- Researchers uncover origin of virus-fighting plasma B cells
- Study finds no evidence of lower intelligence in young children who had anesthesia
- Baboons break out of research facility briefly
- Study shows how deployment time increases risk of suicide attempt in soldiers
- Specific odors from malaria infected individuals attract more mosquitoes