Illustration depicting transcribed noncoding elements (TNE or enhancer RNAs) in the brain Credit: Clemens Scherzer, Brigham and Women’s Hospital Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel. New genetic evidence has revealed that these specialized cells […]Continue Reading ...
A hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds back upon itself. Credit: Vossman/ Wikipedia A new study from the Scripps Research laboratory of Sathyanarayanan Puthanveettil, Ph.D., peers deep within the nucleus of developing brain cells and […]Continue Reading ...
Your brain is structured to make the best possible decision given its limited resources, according to new research that unites cognitive science and information theory – the branch of mathematics that underlies modern communications technology. Credit: Rensselaer Driving down a dark country road at night, you see a shape ahead on the roadside. Is it […]Continue Reading ...
In their research, Carter, Northcott, Gawad, Easton and colleagues used a genetic sequencing technology called single-cell RNA-seq to measure the continually changing activity of genes in single brain cells. Credit: St. Jude Children’s Research Hospital Researchers at St. Jude Children’s Research Hospital have created a massive database of the changes in gene activity of individual […]Continue Reading ...
At right, a close-up of mouse brain tissue shows an engineered protein (stained green) being expressed by astrocytes, but no other cells. UCLA scientists used this technique to selectively silence astrocytes to explore their roles in mouse behavior. Credit: UCLA Health Repetitive behavior disorders are relatively common. One of the best known in this family […]Continue Reading ...
A pile of cocaine hydrochloride. Credit: DEA Drug Enforcement Agency, public domain A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction. The study, performed by researchers at Rutgers University, New Jersey, was published […]Continue Reading ...
Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Tremor, rigidity and bradykinesia are well known symptoms of Parkinson’s disease, occurring in different combinations in individual patients. However, there have not been any neuronal components that definitively identify the main symptom groupings – including […]Continue Reading ...
Drivers of brain aging. Credit: Daniel G. Amen In the largest known brain imaging study, scientists from Amen Clinics (Costa Mesa, CA), Google, John’s Hopkins University, University of California, Los Angeles and the University of California, San Francisco evaluated 62,454 brain SPECT (single photon emission computed tomography) scans of more than 30,000 individuals from 9 […]Continue Reading ...
Credit: CC0 Public Domain Babies who show lower levels of brain activity in response to social stimuli such as peek-a-boo are more likely to be diagnosed with autism spectrum disorder (ASD), according to research involving UCL. Academics from Birkbeck, University of London, University of Cambridge, King’s College London and UCL used neuroimaging technology (functional near […]Continue Reading ...
Credit: CC0 Public Domain About 2,000 patients in Saskatchewan and 72,000 across Canada experience seizure-like episodes unrelated to epilepsy, but nearly half aren’t receiving followup care, harming their quality of life and driving up health-care costs even after their complex medical condition is properly diagnosed. That’s the conclusion of a research paper published today in […]Continue Reading ...
Credit: CC0 Public Domain Older adults fitted with a cochlear implant to compensate for severe hearing loss have significantly poorer cognitive function than their normal-hearing counterparts, reveals a new study. Hearing loss is a risk factor for cognitive decline and dementia, so this new finding suggests cochlear implants cannot fully compensate for this deterioration in […]Continue Reading ...
The ganglion cell layer of the retina is labelled with red to show the presence of a cell sensitive to motion in the upward direction. In low light, these cells become generalists to help the retina pick up the faintest signals of any kind of motion. Credit: Xiaoyang Yao, Duke University and Amanda J. McLaughlin […]Continue Reading ...
In multiple sclerosis, the immune system attacks the myelin sheaths of the nerve fibres (white). Credit: Ralwel/iStockphoto A team of researchers from the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis it is not only specific T cells that cause inflammation and lesions in the brain. B cells, a […]Continue Reading ...
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