Dr. Abdelrahman Y. Fouda, Dr. Ruth B. Caldwell and research associate Zhimin Xu. Credit: Phil Jones, Augusta University Senior Photographer When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. They have shown for the first time in a mouse […]Continue Reading ...
Credit: CC0 Public Domain A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer’s disease—even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases in Germany. […]Continue Reading ...
Credit: CC0 Public Domain Ageing can cause damage to support cells in the white matter, which in turn may lead to damage in the grey matter of the hippocampus, finds a new study by Cardiff University. The discovery gives researchers a new area to focus on in the search for treatments that can protect cognitive […]Continue Reading ...
Credit: CC0 Public Domain Researchers at The University of Texas at San Antonio have revealed significant insight into cocaine addiction, a phenomenon which has grown significantly in the United States since 2015. Now new data by UTSA shows how the release of the neurotransmitter dopamine changes when working for cocaine. Our brains naturally release dopamine […]Continue Reading ...
Credit: CC0 Public Domain A recent retrospective study evaluating continuous electroencephalography (cEEG) of children in intensive care units (ICUs) found a higher than anticipated number of seizures. The work also identified several conditions closely associated with the seizures, and suggests that cEEG monitoring may be a valuable tool for helping to identify and treat neurological […]Continue Reading ...
Mice with AD-like symptoms receiving supplemental levels of choline in the womb improved their spatial memory. A second generation bred from these choline-treated mice also showed improved spatial memory, suggesting epigenetic changes in genes. Choline acts to reduce harmful levels of the amino acid homocysteine, converting it to the beneficial chemical methionine. Credit: Shireen DoolingBiodesign […]Continue Reading ...
The image illustrates the anatomical connectivity of the ventral tegmental area (VTA). Beier et al. showed that whole-brain input patterns were related to spatial location, but not cell type of VTA neuron populations. Credit: UCI School of Medicine, Kevin Beier A University of California, Irvine-led study reveals that connectivity within the brain appears to be […]Continue Reading ...
The new fluorescent dye can be tailored to bind with specific polymorphic forms of insulin amyloid complexes. Credit: IPC PAS, Grzegorz Krzyzewski Signs of neurodegenerative diseases, appearing years before the emergence of clinical manifestations, can be detected during the examination of medical samples by means of fluorescence microscopy by using new sensitive and selective dyes […]Continue Reading ...
Serotonin neurons and fibers in the mouse brain. Credit: Florida Atlantic University’s Brain Institute Cocaine is a highly addictive psychostimulant that induces complex molecular, cellular and behavioral responses. Despite various approaches and years of pre-clinical studies, effective, mechanism-based therapies to assist with cocaine misuse and dependence are still sorely lacking. Although it is well understood […]Continue Reading ...
PET scan of a human brain with Alzheimer’s disease. Credit: public domain A study from Massachusetts General Hospital (MGH) investigators sheds new light on how the hallmarks of Alzheimer’s disease—amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau—produce their damaging effects in the brain. The findings suggest that strategies directed against both pathologic proteins, […]Continue Reading ...
A still image from the animation showing the needle at work. Credit: Professor Robert McLaughlin, University of Adelaide. A biopsy needle that can help surgeons identify and avoid blood vessels in the brain during surgery has undergone initial tests in humans. A team of researchers and clinicians led by the University of Adelaide has demonstrated […]Continue Reading ...
Image of P. gingivalis’ gingipains in the neurons of Alzheimer’s brain. P. gingivalis gingipains = red, neurons = yellow, astrocytes = green. Credit: Cortexyme, Inc. Cortexyme, Inc., a privately held, clinical-stage pharmaceutical company developing therapeutics to alter the course of Alzheimer’s disease (AD) and other degenerative disorders, today announced publication of a foundational paper supporting […]Continue Reading ...
Strength of brain network connections predicted positive outcomes (red) and negative outcomes (blue). Credit: Yale University By measuring the strength of connections between different brain networks, Yale researchers successfully predicted who would abstain from cocaine during treatment, they report Jan. 4 in the American Journal of Psychiatry. The machine-learning technique developed at Yale—called connectome-based predictive […]Continue Reading ...
by E.j. Mundell, Healthday Reporter (HealthDay)—New research on 12 high school football players tracked for a season found that repeat head impacts affected the boys’ vision—even if those hits didn’t result in concussion. The Indiana University researchers stressed that the changes in vision did seem temporary. But since vision tests are part of certain testing […]Continue Reading ...
PET scan of a human brain with Alzheimer’s disease. Credit: public domain Incorporating genetic diversity into a mouse model of Alzheimer’s disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging (NIA), part of the National Institutes […]Continue Reading ...
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