(HealthDay)—Recommendations have been developed for pharmacovigilance in rheumatology, emphasizing the need for continued monitoring of new drugs, according to a position statement issued by the American College of Rheumatology (ACR). Researchers from the ACR developed a position statement relating to pharmacovigilance with respect to rheumatology treatment. According to the statement, the ACR supports robust pharmacovigilance […]Continue Reading ...
May 10, 2018 The American College of Radiology selected Geraldine McGinty, MD, MBA, FACR, as the 2018 recipient of the William T. Thorwarth, Jr., MD, Award. This honor recognizes individuals who demonstrate outstanding contributions to the field of health policy and economics for radiology. The Thorwarth Award will be bestowed on McGinty May 21 during […]Continue Reading ...
Credit: CC0 Public Domain The role of genetics in the risk of having an immune disease could be missed in research, scientists suggest. Using a combination of stem cells and novel analytical tools, scientists at the Wellcome Sanger Institute and their collaborators discovered that clues to the contribution of genetic variation to disease risk lie […]Continue Reading ...
Model of inflammatory response by Arid5a/Regnase-1. Regnase-1 localizes to the cytoplasm. Arid5a is imported to the nucleus via an importin-α/β1 pathway. In response to inflammation, the Toll-like receptor (TLR) is activated by LPS, and Il6 mRNA is induced by NF-κB. After that, Arid5a interacts with Il6 mRNA and is exported to the cytoplasm. Credit: M. […]Continue Reading ...
Action Points Note that this survey study found that transgender and gender nonconforming (TGNC) youth had significantly poorer mental health and less access to healthcare. Be aware that TGNC youth in this study tended to describe themselves as “equally masculine and feminine” rather than stating a binary gender conformation. Transgender and gender nonconforming (TGNC) youth […]Continue Reading ...
Retinal blood vessels blocked by immune cells can cause vision loss. Credit: Peter Campochiaro Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness. In experiments […]Continue Reading ...
Persistent liver inflammation in sufferers of chronic viral hepatitis is likely caused by interactions between pro-inflammatory immune cells in the liver and products from gut bacteria, according to new work involving A*STAR researchers. The findings identify new therapeutic targets. Chronic viral hepatitis is characterized by persistent inflammation of the liver, but the mechanism that maintains […]Continue Reading ...
For the first time, researchers have uncovered that bad breath can be caused by a genetic defect. A mutation in the gene SELENBP1 leads to the absence of the protein that converts the sulphur compound methanethiol. Researchers from Radboud University and Radboud university medical center have published these findings in Nature Genetics. Bad breath (halitosis) […]Continue Reading ...
Credit: CC0 Public Domain A team of scientists at the University of Cambridge has discovered that specific genes are linked to individual differences in brain anatomy in autistic children. Previous studies have reported differences in brain structure of autistic individuals. However, until now, scientists have not known which genes are linked to these differences. The […]Continue Reading ...
The European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) has developed new classification criteria for idiopathic inflammatory myopathies (IIMs) that generally perform better than existing criteria. The most common subgroups of IIMs in adults are dermatomyositis (DM), polymyositis (PM), and inclusion body myositis (IBM). In children, juvenile dermatomyositis (JDM) is most common. The International Myositis […]Continue Reading ...
An addition to confirming many genes previously implicated in the genetic predisposition to SSc, the study further discovered hundreds of genes that are previously not known to be associated with disease. This provides a new starting point to better understand the disease aetiology, its genetic causes and develop therapies for SSc. Credit: Duke-NUS Medical School […]Continue Reading ...
I need your help. I’m trying to figure out how to get rid of something that’s terribly broken in our process of taking care of patients, and I can’t do it alone. It’s time to kill the referrals process, get rid of them altogether. Every day, a huge proportion of the messages we receive through […]Continue Reading ...
In a nationally representative study, researchers found considerable variation in the rates of hip fractures across US nursing home facilities.Continue Reading ...
Researchers remotely monitor subjects participating in a study at the WSU Sleep and Performance Research Center at WSU Spokane. Credit: WSU Washington State University researchers have discovered a genetic variation that predicts how well people perform certain mental tasks when they are sleep deprived. Their research shows that individuals with a particular variation of the […]Continue Reading ...
Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature […]Continue Reading ...
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