The National Institute of General Medical Sciences of NIH has awarded a Small Business Innovative Research grant to Allele Biotechnology and Pharmaceuticals to develop new single-domain nanoantibody (nAb) therapies for the treatment of sepsis. Sepsis and septic shock are among the leading causes of death in intensive care units (ICUs). The global incidence of sepsis […]Continue Reading ...
An antibody (dark grey) is binding to an HIV envelope protein (coloured) on the surface of the virus (light grey). Credit: University of Zurich Around one percent of people infected with HIV produce antibodies that block most strains of the virus. These broadly acting antibodies provide the key to developing an effective vaccine against HIV. […]Continue Reading ...
A new generation of broadly neutralizing antibodies provides a novel approach to treating HIV infection. The research group of Prof Florian Klein, Director of the Institute of Virology at the University Hospital Cologne and scientist at the German Center for Infection Research (DZIF), has collaborated with scientists at the Rockefeller University in New York and […]Continue Reading ...
August 10, 2018 A one-two punch of powerful antibodies may be the best way to stop Ebola virus, reports an international team of scientists in the journal Cell. Their findings suggest new therapies should disable Ebola virus’s infection machinery and spark the patient’s immune system to call in reinforcements. “This study presents results from an […]Continue Reading ...
July 30, 2018 Beckman Coulter Life Sciences now offers its largest portfolio of single color CE-IVD and ASR (analyte-specific reagent) conjugated antibodies. With the recent launch of two Kappa and two Lambda polyclonal antibodies, the company has introduced more than 30 additional CE-IVD reagents and 10 new ASRs in the last year. The entire portfolio […]Continue Reading ...
July 20, 2018 Scientists at the Mainz University Medical Center and the Max Planck Institute for Polymer Research (MPI-P) have developed a new method to enable miniature drug-filled nanocarriers to dock on to immune cells, which in turn attack tumors. In the future, this may lead to targeted treatment that can largely eliminate damage to […]Continue Reading ...
July 3, 2018 Antibodies against multiple Plasmodium falciparum proteins (or antigens) can be measured using a simple, accurate and reproducible assay that requires very small amounts of blood. In a series of recently published articles, a team led by ISGlobal – an institution supported by “la Caixa” Foundation – reports the development and optimisation of […]Continue Reading ...
Patients with an autoimmune disorder called antineutrophil cytoplasmic antibody-associated vasculitis produce antibodies that damage blood vessels in the body. In some cases, patients’ antibodies target a protein called myeloperoxidase. New research published in Arthritis & Rheumatology indicates that for patients in remission, reappearance of antibodies against myeloperoxidase is a sign that patients will experience a […]Continue Reading ...
IONTAS Limited (IONTAS), a leader in the discovery and optimisation of fully human antibodies, today announced a collaborative paper published in Nature Communications with the Technical University of Denmark, and the Instituto Clodomiro Picado of the University of Costa Rica describing the development of a panel of human antibodies that neutralise elements of black mamba […]Continue Reading ...
Aug 24 2018 Two types of human antibodies that target different parts of the Ebola virus synergize their antiviral effects by inhibiting different steps of infection, according to a study published August 23 in the open-access journal PLOS Pathogens by Philipp Ilinykh and colleagues from the University of Texas Medical Branch, Vanderbilt University, and Ragon […]Continue Reading ...
August 9, 2018 A team at Scripps Research has come up with a faster way to analyze the outcome of experimental vaccines against HIV and other pathogens. Their new system lets scientists quickly assess the full spectrum of antibodies produced in an individual in response to a pathogen or vaccine and determine if these antibodies […]Continue Reading ...
July 31, 2018 Researchers at Vanderbilt University Medical Center and their colleagues are a step closer to developing a broadly effective antibody treatment against the three major Ebola viruses that cause lethal disease in humans. Reporting July 17 in the journal Immunity, they describe the isolation of two potent monoclonal antibodies from human survivors of […]Continue Reading ...
July 17, 2018 Many donor kidneys that are transplanted are rejected by the recipient within ten years after transplantation. One reason for this are immunoglobulin G antibodies (IgG), which act against human leukocyte antigens (HLA), a tissue characteristic on transplants, and cause rejection. As a result, IgG antibodies are biomarkers for an increased risk of […]Continue Reading ...
This protein structure diagram illustrates the location of the fusion peptide epitope (red) on the HIV spike (green), which projects out of the viral membrane (grey). The diagram also shows how a broadly neutralizing antibody (yellow) binds to the fusion peptide. Credit: NIAID An experimental vaccine regimen based on the structure of a vulnerable site […]Continue Reading ...
June 19, 2018 Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized ‘miniecosystems’ to quickly see if a molecule can function as a potential therapeutic. As they report today in the journal Proceedings of the National Academy of Sciences, the new method will let researchers save critical time […]Continue Reading ...
- Scientists uncover possible new causes of Tourette syndrome
- Girl undergoes unusual heart surgery after compassionate-use exemption | News Center
- Health Issues That Are Sometimes Mistaken for Gluten Sensitivity
- Elective induction of labor at 39 weeks may be beneficial option for women and their babies
- New smart watch algorithms can accurately monitor wearers’ sleep patterns
- Researchers demonstrate epigenetic memory transmission via sperm
- FDA, DHS announce memorandum of agreement to address cybersecurity in medical devices
- Health Tip: Know the Risks of Chicken Pox
- Immunotherapy effective against hereditary melanoma
- Researchers reveal new mechanism for how animal cells stay intact | News Center
- Alzheimer's Goes Under the Cryo-Electron Microscope
- Medicare for all? CMS chief warns program has enough problems already
- Metrohm Raman introduces Mira P handheld Raman system
- Expanding the knowledge about hippocampus to better understand cognitive deficits in MS
- Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features
- Many healthy children may have metabolic risk factors, finds study
- A new antibiotic could be a better, faster treatment for tuberculosis
- “I will not become a Robot Doctor”: A medical student vows to practice compassion
- Study findings may explain sporadic outbreaks of C. difficile infections in hospitals
- Purdue researchers develop new chemical process to find better drug ‘fits’ for patients