Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Researchers from the University of Barcelona have shown that defective versions of human brain cells called astrocytes are linked to the buildup of a toxic protein that is the hallmark of Parkinson’s disease. The studied […]Continue Reading ...
Altered astrocytes may be the root of epilepsy development Researchers at the Fralin Biomedical Research Institute at VTC have identified a cellular response in mice to mild traumatic brain injuries that may lead to seizures. Traumatic brain injury is a leading cause of epilepsy, which is characterized as the repeated occurrence of seizures. No treatments […]Continue Reading ...
A professor of neuroscience at the University of Wisconsin-Madison has shown how a single mutation in a protein found in astrocytes reproduces fibrous globs that devastate cellular function. Image Credit: Anusorn Nakdee / Shutterstock The globs disrupt the positioning of cellular processing units, interrupt signal and energy within the brain and hinder the formation of […]Continue Reading ...
May 4, 2018 A study by scientists of the German Center for Neurodegenerative Diseases (DZNE) points to a novel potential approach against Alzheimer’s disease. In studies in mice, the researchers were able to show that blocking a particular receptor located on astrocytes normalized brain function and improved memory performance. Astrocytes are star-shaped, non-neuronal cells involved […]Continue Reading ...
April 4, 2018 An advance by UCLA neuroscientists could lead to a better understanding of astrocytes, a star-shaped brain cell believed to play a key role in neurological disorders like Lou Gehrig’s, Alzheimer’s and Huntington’s disease. Reported in Neuron, the new method enables researchers to peer deep inside a mouse’s brain and watch astrocytes’ influence […]Continue Reading ...
March 27, 2018 Scientists have found a genetic trigger that may improve the brain’s ability to heal from a range of debilitating conditions, from strokes to concussions and spinal cord injuries. A new study in mice from UT Southwestern’s O’Donnell Brain Institute shows that turning on a gene inside cells called astrocytes results in a […]Continue Reading ...
June 6, 2017 Neurons have lengthy loved the highlight in neuroscience–and for excellent reason why: they’re extremely vital mobile actors. However, increasingly more, star-shaped give a boost to cells referred to as astrocytes are being observed as greater than bit avid gamers within the mind’s wealthy competition. Salk researchers reported a brand new approach of […]Continue Reading ...
Might 2, 2017 The end of our optic nerve is most often the primary position injured by means of glaucoma. Now researchers wish to know if the tough ache drugs (+)-pentazocine can lend a hand keep away from the wear. Their focal point is star-shaped mind cells referred to as astrocytes that in most cases […]Continue Reading ...
Researchers at the University of Barcelona have found that defects in brain glial cells called astrocytes are linked to the accumulation of alpha-synuclein; a toxic protein that is thought to contribute to Parkinson’s disease. Antiv | Shutterstock The astrocytes, which were derived from patients with Parkinson’s, had a genetic mutation that affects cell clean-up capabilities. […]Continue Reading ...
Aug 22 2018 Researchers at Lund University in Sweden have developed a faster method to generate functional brain cells, called astrocytes, from embryonic stem cells. Astrocytes play a significant role in neurodegenerative diseases. The new method reduces the time required to produce the cells from months to two weeks, and the study has been published […]Continue Reading ...
April 16, 2018 Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS. There are compelling evidence that glial and immune cells contribute to the progression of […]Continue Reading ...
Reactive astrocytes surround the lesion site in the injured spinal cord. A new mouse study shows that triggering a gene inside astrocytes activates the star-shaped cells and may improve the brain’s ability to heal from a range of debilitating conditions, from strokes to concussions and spine injuries. Credit: Meifan Amy Chen, Ph.D. UT Southwestern Scientists […]Continue Reading ...
October 5, 2017 Star-shaped cells called astrocytes are much more than simple support cells in the brain. In a new study on mice, researchers at Karolinska Institutet demonstrate that they also play a key part in the respiratory center of the brainstem and release inflammatory molecules that regulate breathing. The results, which are presented in […]Continue Reading ...
Would possibly four, 2017 Neuroscientists at Tufts College Faculty of Medication have found out a brand new signaling pathway that immediately connects two main receptors within the mind related to finding out and reminiscence – the N-methyl-D-aspartate receptor (NMDAR) and the alpha 7 nicotinic acetylcholine receptor (a7nAChR) – which has importance for present efforts to […]Continue Reading ...
Hundreds of branches and branchlets emanate from an astrocyte’s cellular frame, which is the dense portion in the midst of the picture. Credit score: Baljit Khakh/UCLA From afar, the billions of stars in our galaxy glance indistinguishable, simply because the billions of star-shaped astrocytes in our brains seem the similar as each and every different. […]Continue Reading ...
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