A genome-wide association study in Biological Psychiatry examines the role of copy number variants in subtypes of bipolar disorder A form of rare genomic structural variation called copy number variants (CNVs) may be more closely associated with schizophrenia than bipolar disorder. A new study published in Biological Psychiatry failed to find that CNVs were associated […]Continue Reading ...
A new study by researchers at The Picower Institute for Learning and Memory at MIT finds that the protein CPG2 is significantly less abundant in the brains of people with bipolar disorder (BD) and shows how specific mutations in the SYNE1 gene that encodes the protein undermine its expression and its function in neurons. Led […]Continue Reading ...
Not much is known about how bipolar disorder (BD) affects people throughout their lives. Do women and men differ in the severity of their symptoms? Does a person’s age when a bipolar diagnosis is made have any bearing on how severe the symptoms are? How do other medical conditions affect symptoms of BD across the […]Continue Reading ...
August 9, 2018 Mood disorders like major depressive disorder (MDD) and bipolar disorder are often complex and hard to diagnose, especially among youth when the illness is just evolving. This can make decisions about medication difficult. In a collaborative study by Lawson Health Research Institute, The Mind Research Network and Brainnetome Center, researchers have developed […]Continue Reading ...
By Sally Robertson, BScJune 11, 2018 Researchers from the RIKEN Center for Brain Science in Japan have discovered a genetic mutation that may increase the risk of bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. Image Credit: Andrii Vodolazhskyi / Shutterstock The finding could help researchers develop more effective […]Continue Reading ...
April 5, 2018 A blood test may have the potential to speed accurate diagnosis – and proper treatment – of bipolar disorder in children, new research suggests. Researchers at The Ohio State University found that children with bipolar disorder had higher blood levels of a protein associated with vitamin D compared to children without mood […]Continue Reading ...
March 21, 2018 An app that one day may help predict and monitor manic and depressive episodes in people with bipolar disorder is now available in the App Store. The app, called BiAffect, was designed by researchers at the University of Illinois at Chicago, along with collaborators at the University of Michigan, Arbormoon Software and […]Continue Reading ...
Be told concerning the signs of bipolar dysfunction, a situation characterised by means of alternating sessions of utmost low and high moods, in addition to how it’s controlled.Continue Reading ...
In patients with psychiatric disorders, stability of symptoms has important implications for diagnosis, prognosis, and treatment. Two reviews of symptom stability over the course of psychiatric disorders – bipolar disorder and psychotic disorders, respectively – were published online by the Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer. […]Continue Reading ...
New research has found that neurons deep inside the brain could hold the key to accurately diagnosing bipolar disorder and depression. The research team used sophisticated MRI scanning to see how the amygdala – a set of neurons that play a key role in processing emotions – reacts as a patient processes facial expressions such […]Continue Reading ...
July 23, 2018 Psychologists at Lancaster University have devised a novel psychological intervention to address Anxiety in Bipolar Disorder (AIBD). Anxiety is common in Bipolar Disorder (BD) and associated with worse clinical outcomes including increased suicidality. Despite effective psychological treatments for anxiety, research into treating anxiety in BD is underdeveloped. Researchers led by Professors Steven […]Continue Reading ...
June 11, 2018 Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, but the link between levels of the neurotransmitter serotonin and mitochondrial dysfunction had not been established. Researchers at […]Continue Reading ...
Cardno AG, Owen MJ. Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder. Schizophr Bull. 2014 May;40(3):504-15. doi: 10.1093/schbul/sbu016. Epub 2014 Feb 24. Review. Craddock N, Jones L, Jones IR, Kirov G, Green EK, Grozeva D, Moskvina V, Nikolov I, Hamshere ML, Vukcevic D, Caesar S, Gordon-Smith K, Fraser C, Russell E, Norton N, Breen […]Continue Reading ...
MARLBOROUGH, Mass.–(BUSINESS WIRE)– March 6, 2018 — Sunovion Pharmaceuticals Inc. (Sunovion) today announced that the U.S. Food and Drug Administration (FDA) approved a supplemental New Drug Application (sNDA) that expands the use of Latuda (lurasidone HCI) to include the treatment of major depressive episode associated with bipolar I disorder (bipolar depression) in pediatric patients (10 […]Continue Reading ...
Credit score: Martha Sexton/public area Johns Hopkins researchers file they’ve genetically engineered mice that show lots of the behavioral hallmarks of human bipolar dysfunction, and that the odd behaviors the rodents display can also be reversed the usage of well-established drug remedies for bipolar dysfunction, equivalent to lithium. Particularly, the mice lacked the protein ankyrin-G, […]Continue Reading ...
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