Measurement of AHNAK2 helps physicians make challenging diagnostic decisions, according to a new study in The American Journal of Pathology Label-free digital pathology using infrared (IR) imaging with subsequent proteomic analysis for bladder cancer (BC) has revealed the first protein biomarker (AHNAK2) for BC. AHNAK2 differentiates between chronic cystitis (inflammation of the bladder) and a […]Continue Reading ...
Researchers at the School of Medicine have developed a highly sensitive urine test for diagnosing and monitoring bladder cancer. The test involves looking for fragments of cancer DNA in urine samples. “This study describes a new diagnostic approach to bladder cancer focused on analysis of urine samples,” said Maximilian Diehn, MD, PhD, associate professor of […]Continue Reading ...
Credit: Mary Ann Liebert, Inc., publishers A team of researchers developed a novel model of partial bladder outlet obstruction (pBOO) in female swine and used this model to show that even after inducing severe urinary outlet resistance and damage to the bladder, they could achieve significant improvements in bladder capacity through bladder reconstruction using acellular […]Continue Reading ...
A research team led by Tufts University engineers has developed a non-invasive method for detecting bladder cancer that might make screening easier and more accurate than current invasive clinical tests involving visual inspection of bladder. In the first successful use of atomic force microscopy (AFM) for clinical diagnostic purposes, the researchers have been able to […]Continue Reading ...
Scientists have shown for the first time that immune cells in the urine of bladder cancer patients accurately reflect those in the tumor environment, according to research published today (Wednesday) in the Journal of Experimental Medicine. Unexpectedly, the Cancer Research UK-funded study showed that immune cells found in the urine were more representative of the […]Continue Reading ...
Patients with muscle-invasive bladder cancer have been shown to benefit from chemotherapy prior to surgical removal of the bladder. But which type of chemotherapy leads to the best outcomes in terms of complete response rates or cancer control? Moffitt Cancer Center researchers examined data from more than 800 surgical patients with advanced bladder cancer. The […]Continue Reading ...
August 21, 2018 Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test, according to researchers at Brighton and Sussex Medical School (BSMS). This could potentially save months of unnecessary and ineffective treatment. Currently, 30-40% of individuals have no benefit from the standard […]Continue Reading ...
July 26, 2018 Results of the European multi-center study of Bladder EpiCheck™ urine test, supporting reduction of invasive procedures, were published in the European Urology Oncology journal Nucleix Ltd., a leading cancer detection and screening company, announced today that the multi-center European study results with its Bladder EpiCheck™ urine test for the detection of bladder […]Continue Reading ...
Researchers from the Washington University School of Medicine have developed an implantable device that could one day help people with bladder problems, without the need for electronic stimulators or medication. Magic Mine | Shutterstock As reported in the journal Nature, the tiny soft device detects overactivity in the bladder and uses light from integrated LEDs […]Continue Reading ...
We know that the bladder is a poorly understood organ, critical for storing metabolic waste. What we don’t know is how this unique environment impacts bladder immunity to common diseases such as urinary tract infections (UTI) and bladder cancer. With UTI being second only to respiratory infection in prevalence, and bladder cancer being the fifth […]Continue Reading ...
Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck’s anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) or CIS plus papillary disease (Cohort A). […]Continue Reading ...
Sesen Bio, Inc., a late-stage clinical company developing fusion protein therapies for the treatment of cancer, today announced that the company will present its three-month Phase 3 VISTA Trial data during a poster session at the Global Congress on Bladder Cancer 2018. The congress is being held Sept. 20-21, 2018 in Madrid. The ongoing VISTA […]Continue Reading ...
Credit: CC0 Public Domain Patients with muscle-invasive bladder cancer have been shown to benefit from chemotherapy prior to surgical removal of the bladder. But which type of chemotherapy leads to the best outcomes in terms of complete response rates or cancer control? Moffitt Cancer Center researchers examined data from more than 800 surgical patients with […]Continue Reading ...
August 9, 2018 From day one, Robert McMichael has been determined to live the best life he can. Born with muscular dystrophy, he refused to let his physical challenges block his path to achievement and completed medical school and a demanding residency in neurology. When the Mansfield physician was diagnosed with bladder cancer about a […]Continue Reading ...
July 4, 2018 Mount Sinai researchers use data science and genomics to help determine best treatment options for specific types of disease A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report. The cancer, called p53-like bladder cancer, is named after an active gene signature […]Continue Reading ...
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