A new study has found that transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities. The findings support an emerging model that attributes cognitive decline, in part, to aging of blood cells, which are produced in bone marrow. “While prior […]Continue Reading ...
Johns Hopkins investigators has uncovered roles of two types of cells found in vessel walls of fat tissue that may help speed bone repair. Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed […]Continue Reading ...
The bone marrow disease myelofibrosis is stimulated by excessive signaling from vitamin D and immune cells known as macrophages, reveals a Japanese research team. These findings could help to develop alternative treatments that do not target problem genes. The team was led by Research Fellow Kanako Wakahashi and Junior Associate Professor Yoshio Katayama (Kobe University […]Continue Reading ...
Researchers at University Duisburg-Essen, Germany have discovered new blood vessels in the long bones of mice, as well as similar new vessels in human long bones. sciencepics | Shutterstock The vessels, which the scientists have called “trans-cortical vessels” (TCVs), were found to have originate in the bone marrow and traverse cortical bone perpendicularly along the […]Continue Reading ...
Discovery of immune system’s role may help prevent pain, need for new surgery Rutgers researchers have discovered the long-sought reason that many people with joint replacements experience harmful inflammation and bone loss. Their finding, published in Nature Materials, may pave the way for new therapies to reduce pain and prevent the need for follow-up surgery. […]Continue Reading ...
Jan 22 2019 Researchers at Okayama University show how mechanical stress at very early stages of bone development alters expression pattern of the non-collagenous matrix responsible for biological property of the bone. Left panel: A graphical depiction of frontal view of the suture between the right and left parietal bones. Tensile stress was applied to […]Continue Reading ...
In ‘game-changing’ finding, bone mass rose 800% after signals were blocked in brains of mice UCLA and UC San Francisco life scientists have discovered a dramatic pattern of bone growth in female mice — research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women. The researchers […]Continue Reading ...
There is little benefit for those over 70 taking higher dose vitamin D supplements to improve their bone strength and reduce the risk of falls, new research has revealed. Older people are often encouraged to take supplements of vitamin D to keep bones, teeth and muscles healthy. But a Newcastle University-led study, published in the […]Continue Reading ...
A new Journal of Bone and Mineral Research study confirms that vitamin D supplementation is less effective in the presence of obesity, and it uncovers a biological mechanism to explain this observation. The study reveals that obese mice have very low levels of the enzyme in the liver that converts vitamin D into 25-hydroxyvitamin D […]Continue Reading ...
(HealthDay)—Old age at onset of early rheumatoid arthritis (RA) is associated with more frequent bone erosions, according to a study published online Nov. 11 in the International Journal of Rheumatic Diseases. Koichi Murata, from Kyoto University in Japan, and colleagues examined how old age at disease onset affects treatment and prognosis in early RA using […]Continue Reading ...
The implants developed by TPU scientists passed preclinical trials In the Ilizarov Orthopedic Center (Kurgan, Russia). These implants form part of the Ilizarov system variation applied for lengthening and correcting the deformations of long tubular bones in children. During the preclinical tests, Tomsk implants made it possible to reduce the terms of limb lengthening two […]Continue Reading ...
A $2.85 million National Institute of Arthritis and Musculoskeletal and Skin Diseases-funded study at IUPUI will advance understanding of how bone cells sense and respond to mechanical force, one of the cues the skeleton relies on to regulate its strength. Additionally, the study will inform the design of novel strategies to offset the negative effects […]Continue Reading ...
Bones are very hard organs. Still they do possess a tight meshwork of blood vessels in their inner cavity, where the bone marrow is located, as well as on the bone surface, that is covered by the highly vascularized periosteum. This is why e.g. bone fractures can bleed extensively. The same blood vessel system is […]Continue Reading ...
OSSIO, an orthopedic fixation company, today announced that its OSSIOfiberTM Bone Pin Family has received 510(k) market clearance from the U.S. Food and Drug Administration (FDA). This first of its kind technology features a proprietary bio-integrative material to provide stability and secure bone fixation during the healing process, leaving no permanent hardware behind. While the […]Continue Reading ...
A handful of brain cells deep in the brain may play a surprising role in controlling women’s bone density, according to new research by UC San Francisco and UCLA scientists. In a study published January 11, 2019 in Nature Communications, researchers showed that blocking a particular set of signals from these cells causes female (but […]Continue Reading ...
- Surprise rheumatoid arthritis discovery points to new treatment for joint inflammation
- A just-right fix for a tiny heart
- Owlstone Medical and Shanghai Renji Hospital collaborate to initiate breath biopsy lung cancer trial
- AMSBIO’s comprehensive portfolio of knock-out cell lines and lysates
- New app reliably determines physicians’ skills in forming accurate, efficient diagnoses
- Peripheral nerve injury can trigger the onset and spread of ALS, shows study
- Researchers uncover mechanisms that prevent tooth replacement in mice
- Once-a-day capsule offers new way to reduce symptoms of chronic breathlessness
- FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Uloric (febuxostat)
- Phone-based intervention aids rheumatoid arthritis care
- Opioid epidemic makes eastern inroads and targets African-Americans
- New identified biomarker predicts patients who might benefit from HER2-targeted agents
- Study offers new insights into mechanisms of changes in erythrocytes under stress
- Antipsychotic polypharmacy may be beneficial for schizophrenia patients
- Researchers investigate how marijuana and tobacco co-use affects quit attempts by smokers
- Patients with diabetes mellitus have high risk of stable ischemic heart disease
- Transparency on healthcare prices played key role in Arizona health system’s turnaround
- A comprehensive, multinational review of peppers around the world
- Study finds modest decrease in burnout among physicians
- A simple change can drastically reduce unnecessary tests for urinary tract infections