Pancreatic cancer cells are known for their ability to thrive under extreme conditions of low nutrients and oxygen, a trait known in the cancer field as “austerity.” The cells’ remarkable resistance to starvation is one reason why pancreatic cancer is so deadly. Now researchers have identified a compound from a Congolese plant that has strong […]Continue Reading ...
New research has shown that many Australians with rare cancers can benefit from genomic profiling. The findings of the patient-driven trial are being presented today at the Clinical Oncology Society of Australia Annual Scientific Meeting and could result in dramatic changes to the way those with rare cancers are diagnosed and treated. The initial data […]Continue Reading ...
Screening Food and Drug Administration (FDA)-approved compounds for their ability to stop cancer growth in the lab led to the finding that the drug flunarizine can slow down the growth of triple-negative breast cancer in an animal model of the disease. Led by researchers at Baylor College of Medicine and the National Taiwan University College […]Continue Reading ...
Researchers at the University of California have developed a CRISPR-based tool called SLICE that can boost the effectiveness of immune cell therapies. Juan Gaertner | Shutterstock Scientists have become expert at manipulating the immune system to target and kill cancer, but although they understand how to reprogram immune cell pathways, they often cannot pinpoint which […]Continue Reading ...
FINDINGS Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells can utilize to obtain glucose, which is key to their survival and promotes tumor growth. The finding provides evidence that SGLT2 may be a novel biomarker that scientists can use to […]Continue Reading ...
Scientists at the University of Southampton have developed a new antibody that could hold the key to unlocking cancer’s defense against the body’s immune system. In a new study published in Immunity, the team, which is based at the Centre for Cancer Immunology, engineered antibodies to target a particularly significant immune receptor called 4-1BB, which […]Continue Reading ...
MONDAY, Nov. 12, 2018 — Few American mothers learn from their health care providers that breastfeeding can reduce the risk of breast cancer, a new study finds. Researchers surveyed more than 700 mothers. Of the 92 percent who said they’d…Continue Reading ...
Ovarian cancer claims the lives of more than 14,000 in the U.S. each year, ranking fifth among cancer deaths in women. A multidisciplinary team at Washington University in St. Louis has found an innovative way to use sound and light, or photoacoustic, imaging to diagnose ovarian tumors, which may lead to a promising new diagnostic […]Continue Reading ...
Mutations in RAS proteins initiate many of the most aggressive tumors, and the search for pharmacological inhibitors of these proteins has become a priority in the battle against cancer. Michail Steklov, Francesca Baietti, and colleagues from the Anna Sablina lab (VIB-KU Leuven Center for Cancer Biology) identified LZTR1 as an evolutionarily conserved component of the […]Continue Reading ...
Breast cancer cells. Credit: NIH Scientists have long known that cancer can hijack a cell’s existing regulatory circuitry and transform healthy cells into deadly malignancies. But a new discovery from UC San Francisco demonstrates that cancer is more than just a mutineer that seizes control of the cell’s administrative operations—it’s also a clever engineer, capable […]Continue Reading ...
A drug increasingly used in combination with radiotherapy to treat a type of cancer that forms in the tonsils or the base of the tongue is inferior to a previously favored option, according to a large, clinical trial led by School of Medicine researchers that tracked patient survival and disease progression. Patients randomized to receive […]Continue Reading ...
Nov 15 2018 Pancreatic cancer death rates in the European Union (EU) have increased by 5% between 1990 and 2016, a report launched today reveals. This is the highest increase in any of the EU’s top five cancer killers which, as well as pancreatic cancer, includes lung, colorectal, breast and prostate cancer. Number of Pancreatic […]Continue Reading ...
Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer (NK) cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies. Now for the first time, scientists will combine […]Continue Reading ...
The leading cause of death in the United States is shifting from heart disease to cancer, but the transition is happening at varying paces across the country and affecting racial and ethnic groups differently, according to new Stanford research. Overall, the news is good: cancer death rates dropped by 16 percent between 2003 and 2015, […]Continue Reading ...
New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalized medicine ever nearer. Professor Laura van ‘t Veer, leader of the Breast Oncology Program at the University of California […]Continue Reading ...
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