Researchers have identified ketamine-induced brain-related changes that are responsible for maintaining the remission of behaviors related to depression in mice — findings that may help researchers develop interventions that promote lasting remission of depression in humans. The study, funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, appears […]Continue Reading ...
Ketamine structural model. Credit: University of Maryland School of Medicine Effective treatment of clinical depression remains a major mental health issue, with roughly 30 percent of patients who do not respond to any of the available treatments. Researchers at the University of Maryland School of Medicine (UMSOM) have discovered a crucial receptor called mGlu2 that […]Continue Reading ...
Anaesthetic drug ketamine has been recently studied in depressive illness that has not responded to standard medication. Researchers have now found the exact mechanism of how the drug works in the brains of individuals with depression and can keep the symptoms down for more than a week. The results of the study titled, “Sustained rescue […]Continue Reading ...
Credit: CC0 Public Domain Over the past quarter-century, researchers have published hundreds of studies suggesting a small set of particular genes or gene-variants plays a substantial role in boosting susceptibility to depression. Such papers fueled hopes that clinicians could soon use genetic testing to simply identify those at risk, and drug companies could develop medications […]Continue Reading ...
People suffering from treatment resistant depression are at a higher risk of developing substance use disorders than other patients with depression, reports a study by researchers at Karolinska Institutet in Sweden published in the journal Addiction. The risk is highest for sedatives or opiates, which includes the analgesic morphine and heroin. Major depressive disorder – […]Continue Reading ...
In a new study to investigate the relationship among depressive disorders or symptoms, HIV status and mortality, researchers report that symptoms of depression are moderately associated with death among Veterans with HIV but not among those without HIV infection. Depression is the most frequently reported mental health condition in people living with HIV in the […]Continue Reading ...
Effective treatment of clinical depression remains a major mental health issue, with roughly 30 percent of patients who do not respond to any of the available treatments. Researchers at the University of Maryland School of Medicine (UMSOM) have discovered a crucial receptor called mGlu2 that is critical to the mechanism of fast-acting antidepressants such as […]Continue Reading ...
A new large-scale longitudinal study carried out by University of Sussex psychologists has found a clear link between episodes of depression and anxiety experienced by adults in their twenties, thirties and forties, with a decrease in memory function by the time they are in their fifties. The study, published in the British Journal of Psychiatry, […]Continue Reading ...
An international team led by Munich-based researchers has found a genetic score that reliably predicts the risk, severity and age of onset of depression in young people. The study also confirms a history of childhood abuse as a risk factor. According to the World Health Organization, depression is now the leading cause of disability, globally […]Continue Reading ...
The World Health Organization (WHO) calls depression one of the most serious mental disorders, and researchers around the world are trying to improve treatment of the disease. Now in the largest meta-analysis ever carried out, researchers from iPSYCH have shown that medicine which inhibits inflammation such as e.g. arthritis medicine can also be effective in […]Continue Reading ...
Over the past quarter-century, researchers have published hundreds of studies suggesting a small set of particular genes or gene-variants plays a substantial role in boosting susceptibility to depression. Such papers fueled hopes that clinicians could soon use genetic testing to simply identify those at risk, and drug companies could develop medications to counteract a few […]Continue Reading ...
One University of Texas at Arlington researcher is working to understand the relationship between cardiovascular disease and depression in a National Institutes of Health-funded project. According to the Centers for Disease Control and Prevention, cardiovascular disease is the leading cause of death in the U.S., killing more than 600,000 people each year, and the approximately […]Continue Reading ...
WEDNESDAY, March 27, 2019 — Early life stress caused by childhood maltreatment can alter brain structure, which may increase the risk for adverse disease courses in patients with major depression, according to a study published in the April issue of The Lancet Psychiatry. Nils Opel, M.D., from the University of Münster in Germany, and colleagues […]Continue Reading ...
Sage therapeutics’ Zulresso became the first drug approved for postpartum depression by the United States Food and Drugs Administration (FDA). This cause the shares of Sage to rise by over 5 percent on Tuesday this week. Image Credit: Tolikoff Photography / Shutterstock Brexanolone brand named Zulresso, is being approved for intravenous use in treatment of […]Continue Reading ...
WEDNESDAY, March 20, 2019 — Postpartum depression is a common and often devastating condition for new mothers, but the U.S. Food and Drug Administration on Tuesday approved the first drug to help combat it. The drug, Zulresso (brexanolone), is delivered via intravenous infusion. “Postpartum depression is a serious condition that, when severe, can be life-threatening,” […]Continue Reading ...
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