By loading a chelation drug into a nano-sized homing device, researchers at Clemson University have reversed in an animal model the deadliest effects of chronic kidney disease, which kills more people in the United States each year than breast or prostate cancer. When kidneys stop working properly, calcium builds up in artery tissue, leading to […]Continue Reading ...
Researchers at Boston Medical Center have found that low eye-fluid levels of two proteins associated with Alzheimer’s could serve as a potential predictor of the disease. Shutterstock | Kuttelvaserova Stuchelova The study showed that low levels of amyloid-β and tau proteins in the eye was significantly associated with poor cognitive scores. Alzheimer’s disease is characterized […]Continue Reading ...
Low levels of amyloid-β and tau proteins, biomarkers of Alzheimer’s disease (AD), in eye fluid were significantly associated with low cognitive scores, according to a new study published in the Journal of Alzheimer’s Disease. Led by researchers at Boston Medical Center, the study is the first to connect these known AD protein biomarkers in the […]Continue Reading ...
Credit: CC0 Public Domain Researchers at the Lions Eye Institute (LEI) and The University of Western Australia have pioneered a study of the world’s first and only laboratory model of a rare type of retinal disease, paving the way for new treatment pathways. Cone dystrophy with supernormal rod response (CDSRR) is an inherited disease which […]Continue Reading ...
A major new study from the UC Davis Alzheimer’s Center has uncovered dramatic differences in the brains of Hispanics with a dementia diagnosis compared with those of non-Hispanic whites and of African Americans. The first-of-its-kind study, based on extensive analyses of autopsied brains, found that Hispanics diagnosed with dementia were much more likely to have […]Continue Reading ...
Credit: Louisiana State University Dr. Paul Harch, Clinical Professor and Director of Hyperbaric Medicine at LSU Health New Orleans School of Medicine, and Dr. Edward Fogarty, Chairman of Radiology at the University of North Dakota School of Medicine, report the first PET scan-documented case of improvement in brain metabolism in Alzheimer’s disease in a patient […]Continue Reading ...
It’s no secret that our genes are what makes us… us! But genes are often also the basis for debilitating diseases. One of the major clues to understanding any illness is seeing which genes are acting unusually during disease onset. But it’s not often clear if unusual gene activity is unique to the disease at […]Continue Reading ...
What do your genes say about your ischemic heart disease risk? This study is examining genes to see which ones might contribute to ischemic heart disease risk. To participate in this study, you must be a nonsmoker between ages 45 and 65. This study is located in Bethesda, Maryland. Are you an adult who takes […]Continue Reading ...
The choices we make every day can have a lasting effect on our heart and vascular health. Adopting a heart healthy eating plan, getting more exercise, avoiding tobacco and managing known risk factors are among the key recommendations in the 2019 Primary Prevention of Cardiovascular Disease guideline from the American College of Cardiology (ACC) and […]Continue Reading ...
High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia A new technique using patients’ own modified cells to treat Crohn’s disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months. Researchers at the NIHR […]Continue Reading ...
A two-week treatment course for adult patients with chronic Chagas disease showed, when compared to placebo, similar efficacy and significantly fewer side effects than the standard treatment duration of eight weeks, according to the results of a clinical trial in Bolivia led by the Drugs for Neglected Diseases initiative (DNDi). Chagas disease affects an estimated […]Continue Reading ...
Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Universidad de Oviedo have discovered a new molecular mechanism involved in the premature development of atherosclerosis in mice with Hutchinson-Gilford progeria syndrome (HGPS). Moreover, the results, published in EMBO Molecular Medicine, identify a potential therapeutic target for this severe genetic disease, which is characterized […]Continue Reading ...
High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia The largest study ever to look at why an expensive and commonly used group of drugs fails patients with Crohn’s disease has concluded that standardised drug doses are often too low. A UK wide collaboration led by the University of Exeter and […]Continue Reading ...
Researchers have identified that dysfunction of a specific immune cell, called B cells, underlies lung disease that affects patients with the rare immunological disorder known as common variable immunodeficiency (CVID). Therapeutically targeting these B cells improved the lung disease in all patients they treated. This was the largest study ever conducted for treatment of CVID […]Continue Reading ...
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