Mar 13 2019 Whether revealing a perpetrator with DNA evidence, diagnosing a pathogen, classifying a paleontological discovery, or determining paternity, the duplication of nucleic acids (amplification) is indispensable. In the journal Angewandte Chemie, scientists have now introduced a new, very simple, yet highly sensitive and reliable method that avoids the usual heating and cooling steps, […]Continue Reading ...
Mar 11 2019 Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with weaknesses in repairing their DNA. The study […]Continue Reading ...
Interview with Chris Moreland, Global Product Manager, Integrated Solutions, Promega, conducted by James Ives. Why do scientists need to amplify bacterial DNA for molecular identification and serotyping of food-borne pathogens? Identifying microbes is incredibly important in many industries and is often seen as quality assurance to make sure that the food manufactured or the ingredients […]Continue Reading ...
The gene-editing CRISPR-Cas9 system and other DNA-altering tactics are often likened to editing a Word document through cutting and pasting. But the reality is, editing DNA is not always clean cut. In keeping with the same simile, gene editing can actually be more akin to editing the word “book” to “boot,” and as a result, […]Continue Reading ...
When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in ‘Nature Cell Biology‘, to which scientists from Helmholtz Zentrum Muenchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms. The trick the scientists […]Continue Reading ...
Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA. These modifications — or “epigenetic” marks — help control gene expression and their aberrant distribution across the genome contributes to cancer progression and resistance to therapy. Led by Chunxiao Song and Benjamin […]Continue Reading ...
Researchers at The University of Queensland have discovered a DNA modification that enhances our ability to extinguish fear. The findings, published in the journal Nature Neuroscience, could help guide the development of new treatments for fear-related anxiety disorders. Professor Timothy Bredy of UQ’s Queensland Brain Institute (QBI) said while fear is an important survival mechanism […]Continue Reading ...
DNA is small. Really, really, small. So, when researchers want to study the structure of a single-stranded DNA, they can’t just pull out their microscopes: they have to get creative. In a study published this week in Scientific Reports, researchers from Japan’s Osaka University explain how they came up with a really small solution to […]Continue Reading ...
Researchers from the University of Copenhagen have identified a specific mechanism that protects our cells from natural DNA errors – an ‘enemy within’ – which could permanently damage our genetic code and lead to diseases such as cancer. The study has just been published in one of the most influential scientific journals, Nature Cell Biology. […]Continue Reading ...
DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. Activation of this response underpins genome integrity, which is crucial for preventing the onset of many human […]Continue Reading ...
In a new study, researchers from the University of Copenhagen have identified one of the main mechanisms behind the repair of serious damage to the human DNA. A ‘scanner’ inside the cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched. Damage to the human DNA can cause unstable genetic […]Continue Reading ...
Feb 25 2019 During the DNA synthesis process in a laboratory, recordings can be made of the subtle, telltale noises made by synthesis machines. And those captured sounds can be used to reverse-engineer valuable, custom-designed genetic materials used in pharmaceuticals, agriculture and other bioengineering fields. Researchers from the University of California, Irvine and the University […]Continue Reading ...
Lab instruments are important tools throughout research and health care. But what if those instruments are leaking valuable information? When it comes to biosecurity, this could be a very real threat, according to a group of researchers at the University of California, Irvine, and the University of California, Riverside. By simply recording the sounds of […]Continue Reading ...
As the threat of antibiotic resistance looms, microbiologists aren’t the only ones thinking up new solutions. James Zou, PhD, assistant professor of biomedical data science at Stanford, has applied machine learning to create an algorithm that generates thousands of entirely new virtual DNA sequences with the intent of one day creating antimicrobial proteins. The algorithm, called Feedback GAN, […]Continue Reading ...
- Piece of puzzle unlocked in what drives alcohol addiction
- Researchers investigate whether Zika reservoirs are found in the Americas
- Compounds found in coffee may inhibit growth of prostate cancer
- Lab Innovations returns to the NEC on 30 & 31 October 2019
- How genes affect tobacco and alcohol use
- Plant cellulose bone implants are “viable” option to support new bone growth, study finds
- Older people living in retirement communities benefit from improved health
- UTSA professor helps train first responders to detect prescription opioid overdoses
- Biohaven’s Verdiperstat Receives Orphan Drug Designation From FDA For Multiple System Atrophy
- Smoking may limit body’s ability to fight dangerous form of skin cancer
- Researchers receive $9.7-million grant to develop new hearing-loss treatments for deaf
- TGen and ABL sign agreement to distribute new TB test technology
- UCD researchers lead development of new urine test to detect prostate cancer
- Miniature brains that can move muscles, grown in the lab
- Servier and Oncodesign announce research and drug development partnership
- FDA warns marketer of unapproved products claiming to treat addiction, chronic pain
- TB Medicine Pretomanid Enters Regulatory Review Process in the United States
- Breastfeeding can erase effects of prenatal violence for newborns
- Tens of Thousands of Heart Patients May Not Need Open-Heart Surgery
- Space worries – shingles affecting astronauts says NASA