Differences in the geographic origin of genes may affect the function of human mitochondria–energy-generating organelles inside of cells–according to a new study. Mitochondria have their own genome, separate from the nuclear genome contained in the nucleus of the cell, and both genomes harbor genes integral to energy production by mitochondria. The study explores whether these […]Continue Reading ...
In the January 7th edition of Communications Biology, researchers at InsideOutBio argue that an unusual form of DNA with a reverse twist may have helped thwart the invasion of the human genome by junk DNA. This mechanism has subsequently evolved in one defending against modern day pathogens. During its evolution, the human genome was under […]Continue Reading ...
It’s 2019 and time is flying by. Like many parents, for me the passage of time is marked most dramatically by watching my children as they (somehow, miraculously) morph into smart, capable teens and young adults. The inevitable, dramatic changes that occur during this transition got me thinking about a recent discussion I had with […]Continue Reading ...
Nature has made extravagant use of a simple molecule–DNA, the floorplan of all earthly life. Inventive researchers have used the same base-pairing properties that bond two strands of DNA into the familiar double helix to build innumerable useful structures at the nanometer scale. One such method, known as DNA origami, has yielded rich results in […]Continue Reading ...
Kinetoplastid and apicomplexan parasites include protozoans which are responsible for human diseases, and cause a serious impact on human health and the socioeconomic growth of developing countries. Chemotherapy is the main option to control these pathogenic organisms. The organisms’ nuclear metabolism is considered a promising area for the provision of antimicrobial therapeutic targets. The viability […]Continue Reading ...
An enzyme encircles the double helix to repair a broken strand of DNA. Credit: Tom Ellenberger/Washington University School of Medicine in St. Louis, Dave Gohara/Saint Louis University School of Medicine Mutations in the BRCA1 and BRCA2 genes pose a serious risk for breast and ovarian cancer because they endanger the genomic stability of a cell […]Continue Reading ...
Researchers from the Andalusian center for Molecular Biology and regenerative Medicine (CABIMER) and from the University of Seville have taken a step forward with a study of something as essential for life as the molecules of DNA. They have studied the role of the protein PIF1, capable of undoing different structures in these molecules. These […]Continue Reading ...
Researchers at the University of Queensland have developed a potentially game-changing new technology that could revolutionize cancer point-of-care (POC) diagnostics. LightSpring | Shutterstock The new method will enable quick and easy detection of any cancer from any type of body tissue such as blood or biopsy. The researchers developed the technology after discovering a unique […]Continue Reading ...
Elongated segments of DNA cause Huntington’s disease and certain other disorders of the brain. Researchers funded by the SNSF have developed a method to determine the length of the mutated genes quickly and easily. People with Huntington’s disease suffer from jerky body movements and decreasing mental abilities. The condition usually leads to death 15-20 years […]Continue Reading ...
In a study in Nature, researchers at Karolinska Institutet present a new method for analyzing how instructions in the genome control how our genes are activated in individual cells. The results give new insights into how the genome encodes for its own use, which increases our basic understanding of how genes are activated in different […]Continue Reading ...
When the last Ice Age ended, about 10,000 years ago, pockets of migratory ocean threespine sticklebacks colonized newly formed lakes and streams in coastal regions, and then evolved independently in response to their new local environments. As a result, many of these populations show significant differences in body structure. Marine sticklebacks, for example, have a […]Continue Reading ...
A new study has revealed that cannabis or marijuana can alter the DNA or genetic make-up of the sperms and this can have long term consequences in the baby born of that sperm. The study results were published in the latest issue of the journal Epigenetics. Marijuana. Image Credit: ShutterstockProfessional / Shutterstock Researchers at the […]Continue Reading ...
Scientists revealed how DNA damage influences mutations. Turned out that its contribution to mutagenesis was underestimated and many of the inheritance mutations are caused not by errors in DNA doubling, but by damage to this fragile molecule. The study was conducted by an international research group and published in Nature Genetics. Unfortunately, the reasons for […]Continue Reading ...
Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication. The enzyme Dna2 participates in DNA repair, but little is known about the consequences of its absence on chromosome instability. A study published in the journal Nature by researchers […]Continue Reading ...
From January 1, 2019, the German Research Foundation (DFG) will be funding the new Collaborative Research Center (CRC) 1361 on Regulation of DNA Repair & Genome Stability. Professor Helle Ulrich of Johannes Gutenberg University Mainz (JGU) will assume the role of spokesperson of the group, which will also include the Institute of Molecular Biology gGmbH […]Continue Reading ...
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