Genetic edits and protein restoration in mouse models of Duchenne muscular dystrophy remain viable one year after single CRISPR treatment Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease — Duchenne muscular dystrophy (DMD) — for more than a year […]Continue Reading ...
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease. There is currently no cure or […]Continue Reading ...
Credit: CC0 Public Domain In a new study, researchers from the Danish iPSYCH project demonstrate that people with the highest genetic propensity are over two and a half times as likely to be treated in a psychiatric hospital for depression compared to people with the lowest propensity. This knowledge could be utilised to strengthen preventative […]Continue Reading ...
Feb 12 2019 Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations. This has given families answers about the cause of their children’s serious symptoms. The study was published in the scientific journal PLOS Genetics and the goal is to […]Continue Reading ...
A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran’s Affairs (VA), has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension. The study, an international effort using data from sources including the VA Million Veteran Program (MVP) and United Kingdom (UK) Biobank, is […]Continue Reading ...
Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease. By investigating the DNA of individual blood cells of both children and then modelling the genetic defect in a mouse model, the research team led by Adrian […]Continue Reading ...
A recent study from Uppsala University has found that whether you store your fat around the trunk or in other parts of your body is highly influenced by genetic factors and that this effect is present predominantly in women and to a much lower extent in men. In the study, which is published in Nature […]Continue Reading ...
It’s no surprise to scientists that variety is the very essence of biology, not just the seasoning, but most previous studies of key brain cells have found little variability in a common cell process that involves how genetic information is read and acted on. The process, called epigenetics, involves chemical or structural “tweaks” to gene […]Continue Reading ...
A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue. The new findings broaden the understanding of how genes can predispose certain individuals to obesity. […]Continue Reading ...
Genetics determines some proteins in HDL, but others are picked up by chance Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first established in 1977 and has been confirmed over […]Continue Reading ...
Credit: CC0 Public Domain Genetic testing improves the diagnoses of abnormalities in developing babies that are picked up during ultrasound scans, scientists report today (31 January) in The Lancet. Scientists from the Wellcome Sanger Institute, University of Cambridge, University of Birmingham, Great Ormond Street Hospital (GOSH) and their collaborators used genome sequencing to improve the […]Continue Reading ...
There is only scant scientific evidence available on whether the genetic risk for developing specific psychiatric disorders or cognitive traits is manifest in brain structure from childhood and, to date, studies have focused primarily on adult populations. The question remains unanswered. New evidence has now been provided by a study led by a researcher from […]Continue Reading ...
Credit: CC0 Public Domain In the largest genetic study of osteoarthritis to date, scientists have uncovered 52 new genetic changes linked to the disease, which doubles the number of genetic regions associated with the disabling condition. Scientists at the Wellcome Sanger Institute, GSK and their collaborators analysed the genomes of over 77,000 people with osteoarthritis. […]Continue Reading ...
Jan 14 2019 As part of an international research project, a group of scientists from the University of Zurich found genetic variants associated with risk tolerance and risky behaviors. It is one of the first studies to link genetic variants with behavioral outcomes, which are relevant to social science research. If we compare two people’s […]Continue Reading ...
Credit: CC0 Public Domain Disorders of the autistic spectrum have been associated with hundreds of genetic variations, which have helped in identifying disturbed intracellular signalling pathways and molecular mechanisms typical to autism. Many gene mutations related to the autism spectrum disorders reside in a gene that produces a protein relevant to synapses, or is important […]Continue Reading ...
- New sepsis test could save thousands of lives
- Cervical cancer could be eradicated by 2100
- Sustained smoking cessation can lower risk of seropositive RA
- Thousands with chronic UTIs are not receiving the treatment they need
- Are teens getting high on social media? The surprising study seeking the pot-Instagram link
- Stanford expands biobank services | News Center
- Scientists identify link between drinking contexts and early onset intoxication among adolescents
- Strong social support may reduce cardiovascular disease risk in postmenopausal women
- Rapid expansion of interventions could prevent up to 13 million cases of cervical cancer within 50 years
- Motif Bio Receives Complete Response Letter From The FDA
- Researchers map previously unknown disease in children
- A skeptical look at popular diets: Going gluten-free
- Podcast: KHN’s ‘What The Health?’ How Safe Are Your Supplements?
- Anticipatory signals in eye movements can help measure attentive capacity, learning with greater precision
- Evening exercise does not negatively affect sleep, may also reduce hunger
- Artificial intelligence technique can be used to identify alcohol misuse in trauma setting
- Overweight, obesity in adolescence associated with increased risk of renal cancer later in life
- BGU develops new AI platform for monitoring and predicting ALS progression
- Researchers discover a new promising target to improve HIV vaccines
- Brief Anesthesia in Infancy Does Not Mar Neurodevelopment