Feb 5 2019 Researchers studying male and female marmosets have homed in on the primate brain circuitry responsible for individual differences in overall anxiety. Their findings, published in JNeurosci, show that increasing levels of the neurotransmitter glutamate in the hippocampus normalizes anxious monkeys’ “fight or flight” response. Previous human and animal studies suggest roles for […]Continue Reading ...
June 8, 2018 As people around the world live longer, the prevalence of age-associated cognitive disorders is growing. Alzheimer’s disease (AD), for which advanced age is the most significant risk factor, currently defies all therapeutic efforts. Experts argue that identifying the onset of this progressive disease as early as possible will advance the fight against […]Continue Reading ...
March 15, 2018 New research shows how the novel drug QNZ-46 can help to lessen the effects of excess release of glutamate in the brain – the main cause of brain injury in stroke. Published in Nature Communications, the study shows how identifying the source of damaging glutamate in stroke leads to discovery of brain […]Continue Reading ...
July 24, 2017 Columbia College Scientific Heart (CUMC) researchers have captured the primary third-dimensional snapshots of the AMPA-subtype glutamate receptor in motion. The receptor, which regulates signaling within the mind, is all for a number of essential mind actions, together with reminiscence and studying. The findings have been revealed as of late in Nature. “With […]Continue Reading ...
July 24, 2017 Columbia College Clinical Middle (CUMC) researchers have captured the primary 3-dimensional snapshots of the AMPA-subtype glutamate receptor in motion. The receptor, which regulates signaling within the mind, is all in favour of a number of vital mind actions, together with reminiscence and finding out. The findings had been printed these days in […]Continue Reading ...
IU professor Sharlene Newman and senior scientist Hu Cheng in the IU Bloomington Imaging Research Facility. Credit: Eric Rudd, Indiana University A study led by Indiana University on neurochemical changes associated with alcohol addiction found that the neurotransmitter glutamate plays a role in some alcohol cravings. Alcohol dependence and alcohol use disorders occur in about […]Continue Reading ...
March 14, 2018 A new study shows that healthy people who take attention deficit hyperactivity disorder (ADHD) drugs experience a surge in the neurotransmitter glutamate in key parts of the brain. And that increase in glutamate is associated with subsequent changes in positive emotion. The findings, published in the journal Neuropsychopharmacology, not only provide clues […]Continue Reading ...
March 17, 2017 Primary depressive dysfunction (MDD) affects 15 million American citizens and is the main reason behind incapacity, but present therapies possess restricted efficacy. Ketamine, which has been repurposed as a all of a sudden performing antidepressant, has emerged as an experimental and doubtlessly promising compound to regard critical despair thru a singular drug […]Continue Reading ...
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