Credit: CC0 Public Domain Sugar can silence a key protein required for colonization by a gut bacterium associated with lean and healthy individuals, according to a new Yale study published the week of Dec. 17 in the journal Proceedings of the National Academy of Sciences. The gut microbiota plays a key role in human health, […]Continue Reading ...
Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease (IBD). Millions of people worldwide suffer from IBD in the form of either ulcerative colitis or Crohn’s disease, and few effective long-term treatments are […]Continue Reading ...
Research on the gut microbiome is one of the most promising areas of science today. In a new special issue of Clinical Gastroenterology and Hepatology, the American Gastroenterological Association (AGA) has taken the deep-dive into the gut microbiome that both scientists and the public are looking for to help them better understand the effects of […]Continue Reading ...
Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 A team of researchers with members from the Netherlands and the U.S. has found differences in the numbers of gut microbes for patients with inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). In their […]Continue Reading ...
Credit: CC0 Public Domain Evaluating the gut microbiota of infants may help identify children who are at risk for becoming overweight or obese, according to results from a recent study published in mBio. The research revealed that gut microbiota composition at 2 years of life is associated with body mass index (BMI) at age 12. […]Continue Reading ...
A study from Baltimore’s Sheppard Pratt Health system has shown that probiotics may serve as a potential therapeutic approach to bipolar disorder and other psychiatric conditions. Kateryna Kon | Shutterstock Lead author Faith Dickerson and colleagues found that among patients hospitalized for mania, those who received a probiotic saw more beneficial effects than those who […]Continue Reading ...
Cellular pathways represent the intricate metabolic connections between the plethora of signaling pathways, and energetic-sensors in organs. To maintain energy balance in body organs these metabolic pathways must act uniformly at any given point in time. This is to ensure organ functionality under specific metabolic changes. A new class of non-coding RNAs, MicroRNA, has recently […]Continue Reading ...
The interactions that take place between the species of microbes living in the gastrointestinal system often have large and unpredicted effects on health, according to new work from a team led by Carnegie’s Will Ludington. Their findings are published this week in the Proceedings of the National Academy of Sciences. The gut microbiome is an […]Continue Reading ...
Millions of people suffer from inflammatory bowel disease (IBD) worldwide, either in the form of ulcerative colitis or Crohn’s disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD. The gut barrier is a single-cell epithelial layer that provides protection against antigens and toxins present in the gut. Gut […]Continue Reading ...
Research conducted at Montana State University shows that microbes in the human gut play an important role in protecting against arsenic toxicity, a problem that affects an estimated 200 million people who are exposed to arsenic through contaminated drinking water. For the past five years, MSU doctoral candidate Michael Coryell has worked with his adviser, […]Continue Reading ...
Many people use the term irritable bowel syndrome to describe general symptoms of gut and bowel dysfunction. But diagnosis requires meeting strict, diagnostic criteria. Known as the ROME criteria, these require a person to be experiencing abdominal pain, on average, at least one day per week. The pain must be associated with two or more […]Continue Reading ...
New gut bacteria may help fight obesity and mental disorders The MyNewGut project has discovered new bacterial species and strains in healthy people that seem to be effective against obesity, metabolic and mental disorders related to stress and obesity (e.g. depression). They do so by influencing the endocrine and immune pathways that have an impact […]Continue Reading ...
Why do orally-administered drugs for diabetes work for some people but not others? According to researchers at Wake Forest School of Medicine, bacteria that make up the gut microbiome may be the culprit. In a review of more than 100 current published studies in humans and rodents, the School of Medicine team examined how gut […]Continue Reading ...
Research increasingly links the gut microbiome to a range of human maladies, including inflammatory bowel disease, diabetes and even cancer. Attempts to manipulate the gut with food rich in healthy bacteria, such as yogurt or kombucha, are in vogue, along with buying commercial probiotics that promise to improve users’ chances against illness. Changing the gut […]Continue Reading ...
The gut microbiome — the world of microbes that inhabit the human intestinal tract — has captured the interest of scientists and clinicians for its critical role in health. However, parsing which of those microbes are responsible for effects on our wellbeing remains a mystery. Taking us one step closer to solving this puzzle, UC […]Continue Reading ...
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