3D Model of the heart by Dr. Matthew Bramlet. Credit: NIH In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement (TAVR), a high number experienced severe and moderate cases of prosthesis-patient mismatch (PPM)—meaning the implanted heart valve is […]Continue Reading ...
In atrial fibrillation (AFib), half of the heart’s four chambers aren’t beating properly, but are dancing around randomly without rhythm. This sounds scary and, in some ways, it’s astonishing that people with AFib can function well at all. But remember that the heart’s upper chambers (the atria), which are malfunctioning in AFib, don’t pump blood […]Continue Reading ...
“I was criss-cross applesauce, with my head down at my feet,” Lizneidy said. People with heart failure can often breathe better if they sleep sitting up, but Alvarado-Lazarit did not yet know about the diagnosis. Alarmed, she woke her daughter and took her to the nearest emergency room. Doctors transferred Lizneidy to the pediatric intensive […]Continue Reading ...
When 12-year-old Lizneidy Serratos was airlifted to the Bay Area in early August, her heart was pumping so weakly that she could not walk or eat. Even the flavor of toothpaste made her nauseated, her pediatric cardiologist, Christopher Almond, MD, told me. At home in Reno, Lizneidy had just been diagnosed with a severe form […]Continue Reading ...
The first successful human heart transplant in the United States was performed at Stanford Hospital 50 years ago. That procedure, by legendary heart surgeon Norman Shumway, MD, PhD, (shown above) led to the standard surgical technique for heart transplantation that’s still in use today. And it’s the reason why patients, like Yolanda, have been given […]Continue Reading ...
The community of microorganisms that live in the human gut has been shown to confer all kinds of health benefits. Now, an international team of researchers has shown in mice that a healthy gut microbiome is important for recovery after a heart attack. Writing today (Oct. 8, 2018) in the journal Circulation, a team led […]Continue Reading ...
WEDNESDAY, Oct. 10, 2018 (American Heart Association) — It’s been 70 years since a small, middle-class community 23 miles west of Boston became the linchpin in helping to solve the mysteries of heart disease. Smoking. Cholesterol. Blood pressure. Obesity. It’s common knowledge today that these all can lead to heart trouble. But in the 1940s, […]Continue Reading ...
Hispanic infants with critical types of congenital heart disease have worse outcomes in their first year than do their non-Hispanic white counterparts, a difference largely driven by their mother’s level of education and type of insurance coverage, according to new research in Journal of the American Heart Association, the Open Access Journal of the American […]Continue Reading ...
Role of crucial gene mutation confirmed When a young athlete suddenly dies of a heart attack, chances are high that they suffer from familial hypertrophic cardiomyopathy (HCM). Itis the most common genetic heart disease in the US and affects an estimated 1 in 500 people around the world. A protein called myosin acts as the […]Continue Reading ...
Credit: Medical Research Council New drugs that lower levels of triglycerides (a type of fat) in blood could further reduce the risk of heart attack when added to statins. These new drugs, which are in various stages of development, could also reduce blood glucose levels and the risk of diabetes, according to a new genetic […]Continue Reading ...
In a study published in iScience, Professor Akiyoshi Fukamizu of the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (University of Tsukuba, JAPAN) and the research group reported a new work on discovery of the important role of PRMT1 in dilated cardiomyopathy(DCM). The heart pumps blood to all organs and tissues of our […]Continue Reading ...
Myocardial infarction (MI) is one of the most common causes of death in the Western world. Typically, MI is caused by the blockage of a coronary artery by an atherosclerotic plaque: as the oxygen supply of the heart drops, cell death occurs. If the patient is hospitalized and the oxygen supply of the heart restored […]Continue Reading ...
People at high risk of a heart attack in adulthood could be spotted much earlier in life with a one-off DNA test, according to new research part-funded by the British Heart Foundation and published today in the Journal of the American College of Cardiology. An international team led by researchers from the University of Leicester, […]Continue Reading ...
Most people who need open heart surgery to repair damaged heart valves are aged 65 or older. The American Heart Association (AHA) estimates that nearly 8 million people have had heart surgeries. However, we don’t fully understand the effects of heart surgery on an older adult’s cognition (the ability to remember, think, and make decisions). […]Continue Reading ...
Figure 1. Schematic for the heart-targeting mechanism of TANNylated protein nanocomplexes: (1) size-dependent permeation, (2) phenolic (that is, TA), and (3) internalization by internalization by myoblasts. Credit: The Korea Advanced Institute of Science and Technology (KAIST) Typical methods of drug delivery to the heart require surgical procedures involving incisions in the chest wall and bones. […]Continue Reading ...
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