Credit: CC0 Public Domain A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found that a high-fat, high-sugar diet in mouse mothers before and during pregnancy causes problems in the hearts of their offspring, and that such problems are passed down at least three generations, […]Continue Reading ...
The commonly used diabetes drug metformin could reverse the harmful thickening of heart muscle that leads to cardiovascular disease, according to a study at the University of Dundee. Scientists led by Professor Chim Lang, Head of the Division of Molecular and Clinical Medicine at Dundee, discovered that metformin has the potential to be repurposed as […]Continue Reading ...
Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators. These proteins, stress hormone receptors known as the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), act in concert to help support heart health. When the signaling between […]Continue Reading ...
When was the last time you measured your resting heart rate? Having a resting heart rate of 75 beats per minute (bpm) during middle-age may double the risk for early death, according to new research published in the journal Open Heart. The study involved hundreds of men who had their resting rates measured on two […]Continue Reading ...
In a major medical breakthrough, Tel Aviv University researchers have “printed” the world’s first 3D vascularised engineered heart using a patient’s own cells and biological materials. Their findings were published on April 15 in a study in Advanced Science. Until now, scientists in regenerative medicine — a field positioned at the crossroads of biology and […]Continue Reading ...
Novo Biosciences Inc., has achieved several major milestones in its mission of bringing its breakthrough drug candidate, trodusquemine (aka MSI-1436), to market as a potential regenerative medicine treatment for heart disease and Duchenne muscular dystrophy (DMD). Trodusquemine is a repurposed drug candidate that has already been shown to be well tolerated by patients. “Trodusquemine holds […]Continue Reading ...
MONDAY, April 8, 2019 (American Heart Association News) — Heart disease and cancer — ruthless conditions that are the nation’s leading causes of death — can sometimes intertwine. Certain cancer treatments can directly damage the heart, while others leave survivors dealing with weight gain or loss of fitness. One way to potentially counteract these heart-related […]Continue Reading ...
Almost one percent of all American babies are born with malformed hearts. Heart abnormalities are at once the most common and most deadly type of birth defect in the U.S. Malformations in the structures of the right side of the heart have been linked to mutations in the master regulator gene Nkx2-5. Researchers at the […]Continue Reading ...
Researchers have designed a new type of adhesive patch that can be placed directly on the heart and may one day help to reduce the stretching of heart muscle that often occurs after a heart attack. The patch, made from a water-based hydrogel material, was developed using computer simulations of heart function in order to […]Continue Reading ...
Researchers from Tel Aviv University have engineered the world’s first perfectly functioning, immunologically, cellular, biochemically and anatomically matched 3D printed heart. The heart is vascularised and supplied by the blood vessels of the patient and is created from the patient’s own cells. The results of this medical breakthrough study titled, “3D Printing of Personalized Thick […]Continue Reading ...
The Framingham Heart Study (FHS), the nation’s longest running cohort study with longitudinal analysis of cardiovascular disease, has been renewed for an additional six years and $38 million dollars from the National Heart, Lung, and Blood Institute (NHLBI). The contract will support examining the elderly groups of the cohort study starting later this year in […]Continue Reading ...
Patients who are African-American or Hispanic, uninsured or covered by Medicaid insurance and living in low-income ZIP codes are less likely to receive a heart-pumping device known as a left ventricular assist device (LVAD), according to preliminary research presented at the American Heart Association’s Quality of Care and Outcomes Research Scientific Sessions 2019, a premier […]Continue Reading ...
Nearly half of current hospital admissions for heart failure are caused by a type of disease with no treatment options. Cardiology researchers at UT Southwestern Medical Center are changing that reality with a fresh approach, recently published in Nature. “There are two types of heart failure. One is called HFrEF, for which we have a […]Continue Reading ...
Zhao and her team have shown the potential of biomimicry to grow microvessels in tissues suitable for a cardiac patch. The next steps will be animal trials and refining medical technology for implants and devices. With the help of tiny, dense, neatly aligned blood vessels, engineered tissues could help hearts, skin, bones and muscles regenerate […]Continue Reading ...
Novel studies from around the world showing cutting-edge clinical use of cardiovascular magnetic resonance (CMR) will be presented at EuroCMR 2019, a meeting of the European Association of Cardiovascular Imaging (EACVI), a branch of the European Society of Cardiology (ESC). This annual gathering will be held 2 to 4 May at the Palazzo del Cinema […]Continue Reading ...
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