In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus’s outer envelope where a lineage of antibodies are able to dock and neutralize the virus. But true to form with HIV, these broadly neutralizing antibodies, or bnAbs, are highly complex and arise under […]Continue Reading ...
One of the goals President Donald Trump announced in his State of the Union address was to stop the spread of HIV in the U.S. within 10 years. In addition to sending extra money to 48 mainly urban counties, Washington, D.C., and San Juan, Puerto Rico, Trump’s plan targets seven states where rural transmission of HIV is […]Continue Reading ...
CRCHUM researchers are exploring a potential therapeutic approach Researchers at the University of Montreal Hospital Research Centre (CRCHUM) have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. In a study published in the journal Nature Communications, they show, in the cells of people living […]Continue Reading ...
Scanning electromicrograph of an HIV-infected T cell. Credit: NIAID Researchers can now quickly and accurately count a hidden, inactive form of the human immunodeficiency virus (HIV) that lurks in patients’ cells. This version of HIV embeds into cells’ genomes and can persist despite otherwise successful therapies—thwarting attempts to cure the infection. Using a new genetic […]Continue Reading ...
The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery. The study is sponsored by the National […]Continue Reading ...
Credit: stock.adobe.com Much of the research on HIV has focused on preventing infection but little is understood about how the body keeps the virus in check post-infection. A new study by Yale investigators reveals the role of a protein that serves to block HIV gene expression once it has entered human cells. The research team, […]Continue Reading ...
George Mason University’s Yuntao Wu is the lead scientist on a research team that has identified a measurable indicator that could prove instrumental in the fight against HIV. The research focuses on cofilin, a key protein that regulates cells to mobilize and fight against infection. In an HIV-infected patient, cofilin dysfunction is a key factor […]Continue Reading ...
Adolescent girls exposed to severe drought conditions in rural Lesotho had higher rates of HIV, according to a new study led by researchers at ICAP at Columbia University, a global health organization based at the Columbia Mailman School of Public Health, and from the Lesotho Ministry of Health and U.S. Centers for Disease Control and […]Continue Reading ...
One of the goals President Donald Trump announced in his State of the Union address was to stop the spread of HIV in the U.S. within 10 years. In addition to sending extra money to 48 mainly urban counties, Washington, D.C., and San Juan, Puerto Rico, Trump’s plan targets seven states where rural transmission of […]Continue Reading ...
HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system’s response to infection than previously thought. Their findings could help inform more effective treatment strategies for HIV, including those aimed at activating the dormant virus in patients before subsequently eliminating it. […]Continue Reading ...
Mice expressing the lectin CD169 capture incoming retroviruses and reduce their systemic dissemination. In contrast, in mice lacking CD169, spread of blood cancer causing retrovirus is enhanced, resulting in heightened infection (green) in the spleen. Credit: Yale University Taking aim at a promising molecular target can combat the spread of retroviruses that can cause blood […]Continue Reading ...
Feb 8 2019 The International AIDS Society (IAS) has announced the plenary presentations that will lead the 10th IAS Conference on HIV Science (IAS 2019), which will take place in Mexico City, Mexico, on 21-24 July 2019. IAS 2019 is the largest open scientific conference on HIV and is expected to bring together more than […]Continue Reading ...
Credit: CC0 Public Domain HIV viral suppression is a positive medical outcome which indicates viral control and inability to transmit infection. It is usually achieved through antiretroviral therapy. There is a lack of research into the psychosocial factors affecting HIV viral suppression, such as perceived neighborhood social cohesion, or how connected the subject feels to […]Continue Reading ...
Noting that science has “brought a once-distant dream within reach,” President Donald Trump on Tuesday night pledged to eliminate HIV transmission within 10 years. “We have made incredible strides, incredible,” Trump said in the annual State of the Union address. “Together, we will defeat AIDS in America and beyond.” It’s a goal long sought by […]Continue Reading ...
A new EU project on the theme of HIV, hepatitis C and tuberculosis is a door opener for collaboration between researchers from EU countries and Russia. One of the project’s initiators is Anders Sönnerborg, Professor of Clinical Virology and Infectious Diseases at KI’s Departments of Laboratory Medicine, and Medicine Huddinge. The project Common Actions Against […]Continue Reading ...
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