Researchers have found that bowel cancer cells have a mechanism by which they can switch off some key molecules on their surfaces and thus escape being recognised and killed by the immunotherapy agents. Image: Colour-enhanced image of human colon cancer cells in culture. Credit: Annie Cavanagh. License: (CC BY 4.0) This may provide clues as […]Continue Reading ...
Cancers can make themselves harder for new immunotherapies to see by ‘changing their spots’ – and switching off a key molecule on the surface of cells that is otherwise recognized by treatment. Researchers found that they could test samples from patients with bowel cancer to identify which were most likely to respond to immunotherapy by […]Continue Reading ...
UNC School of Medicine researcher Edwin Kim, MD, MS, says the results of a multi-year observational study are encouraging for those suffering from peanut allergies Regular dietary peanut consumption after completing oral immunotherapy (OIT) or sublingual immunotherapy (SLIT) for peanut allergy may provide continued protection against accidental exposures to the allergen, according to a new […]Continue Reading ...
Study could help identify patients with glioblastoma who are most likely to respond to immunotherapy. Columbia researchers have learned why some glioblastomas–the most common type of brain cancer–respond to immunotherapy. The findings could help identify patients who are most likely to benefit from treatment with immunotherapy drugs and lead to the development of more broadly […]Continue Reading ...
Fewer than 1 in 10 patients with glioblastoma—the most common type of brain cancer—respond to immunotherapy; a new study reveals how to detect patients who may respond.Continue Reading ...
That was until Dr. Richard Carvajal, director of the Melanoma Service at NewYork-Presbyterian/Columbia, started her on immunotherapy.Continue Reading ...
The strategy for triggering the patient’s own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees. In lung cancer, immunotherapy had proven to extend survival rates for only some variants of the disease. Now, an international clinical trial led by the oncologist Luis Paz-Ares, head […]Continue Reading ...
Nov 7 2018 Researchers at the Mount Sinai School of Medicine have developed a new nanotechnology-based immunotherapy that promotes long-term transplant acceptance in an animal model. Africa Studio | Shutterstock The development, which is described in the journal Immunity, could transform patient care and provide a solution to the problems that stand in the way […]Continue Reading ...
A new study has found that taking probiotics could drastically reduce the response of cancer patients to immunotherapy. Probiotics are freely available without prescription and are not regulated by the US Food and Drug Administration. Lightspring | Shutterstock On the other hand, patients on a fiber-rich diet showed a five-fold increase in response. The study […]Continue Reading ...
National Cancer Centre Singapore and Lucence Diagnostics announce first molecular test that selects immunotherapy for kidney cancer Immunotherapy drugs such as PD-L1 checkpoint inhibitors represent the front-line treatment for kidney cancer. But immunotherapy is expensive, benefits only a subset of patients and is futile in the majority of patients. Now, researchers from National Cancer Centre […]Continue Reading ...
Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair (DDR) achieved significant tumor regression in mouse models of small cell lung cancer (SCLC), suggesting a promising new approach for treating patients with this aggressive cancer. The […]Continue Reading ...
The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy. The study, co-led by Suzanne Topalian, M.D., associate director of the Bloomberg~Kimmel Institute for Cancer Immunotherapy […]Continue Reading ...
A new study suggests that a type of brain tumor in patients with neurofibromatosis type 1 could be treated with immunotherapy, which has so far proved ineffective in treating most brain cancers.Continue Reading ...
Results from a clinical trial using anti-peanut allergy therapy has doctors eyeing the possibility of a new drug that could help change this life-threatening condition into more of a nuisance. The trial tested the efficacy of a new immunotherapy that isolates certain peanut proteins and exposes allergic individuals to minute amounts of the substance. The […]Continue Reading ...
Credit: Broad Institute of MIT and Harvard Unleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable outcomes in some cancer patients, but in many more, cancer cells evade the treatment and continue to spread. Now, a team led by researchers from Broad Institute of MIT and Harvard and Dana-Farber Cancer […]Continue Reading ...
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