Dr. Abdelrahman Y. Fouda, Dr. Ruth B. Caldwell and research associate Zhimin Xu. Credit: Phil Jones, Augusta University Senior Photographer When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. They have shown for the first time in a mouse […]Continue Reading ...
When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report. They have shown for the first time in a mouse model of tough-to-treat optic nerve trauma, that removing the enzyme arginase 2, which increases with injury, decreases neuron death in […]Continue Reading ...
Altered astrocytes may be the root of epilepsy development Researchers at the Fralin Biomedical Research Institute at VTC have identified a cellular response in mice to mild traumatic brain injuries that may lead to seizures. Traumatic brain injury is a leading cause of epilepsy, which is characterized as the repeated occurrence of seizures. No treatments […]Continue Reading ...
Jan 17 2019 Exercise Expert Seeks to Prevent Damage Caused by Restoration of Blood Flow Exercise can protect both muscle and nerves from damage caused by the restoration of blood flow after injury or surgery, new research from the University of Virginia School of Medicine shows. UVA’s Zhen Yan, PhD, is a top expert on […]Continue Reading ...
Stroke and myocardial infarction (MI) are a significant cause of death and disability worldwide. However, over the past several decades because of advances in medicines (thrombolytic agents, antiplatelet drugs, beta blockers, and angiotensin converting enzyme inhibitors) and approaches to restore tissue perfusion (percutaneous coronary intervention and cardiopulmonary bypass), the mortality of MI has declined dramatically. […]Continue Reading ...
Traumatic brain injury, or TBI, is often referred to as the “invisible injury” – while on the surface everything seems normal with brain structure, symptoms may present themselves in the behavior of the injured and cannot be explained. A team from Illinois Institute of Technology, the RDECOM Research Laboratory, the Army’s corporate research laboratory (ARL) […]Continue Reading ...
Disorders of sleep are some of the most common problems experienced by patients after traumatic brain injury (TBI). It is important to recognize and treat these problems early to allow for optimal cognitive recovery, but because they are so common, the importance of treating them is often underestimated. In this special issue of NeuroRehabilitation scientists […]Continue Reading ...
For the first time, scientists have described the body’s natural mechanism for temporarily protecting the powerhouses of kidney cells when injury or disease means they aren’t getting enough blood or oxygen. Powerhouses, called mitochondria, which provide fuel for our cells, start to fragment, likely as one of the first steps in the kidney cell damage […]Continue Reading ...
Similarities in cognitive findings between persons with spinal cord injury and older healthy individuals could indicate accelerated aging of the brain after spinal cord injury A multidisciplinary team of researchers has identified specific cognitive deficits in individuals with spinal cord injury (SCI). Their findings support the theory of accelerated aging after SCI, and have important […]Continue Reading ...
Thousands of people worldwide suffer severe spinal cord injuries each year, but little is known about why these injuries often continue to deteriorate long after the initial damage occurs. Yi Ren, a professor of biomedical sciences at the Florida State University College of Medicine, is making progress in understanding why such significant harm is inflicted […]Continue Reading ...
To help physicians decrease the number of deaths resulting from traumatic brain injuries, Chandan Reddy, associate professor in the Department of Computer Science and faculty at the Discovery Analytics Center, will use new machine learning techniques for computational models to predict short- and long-term outcomes, categorize traumatic brain injury patients, and provide interventions tailored to […]Continue Reading ...
Representative confocal micrograph showing the expression of myelin basic protein (MBP – green) and reactive oxygen species (red) in the brain (midsagittal section) of an 11 day old mouse exposed to experimental necrotizing enterocolitis. Credit: David Hackam Using a mouse model of necrotizing enterocolitis (NEC)—a potentially fatal condition that causes a premature infant’s gut to […]Continue Reading ...
A toddler puts her hand on a hot stove and swiftly withdraws it. Alas, it’s too late–the child’s finger has sustained a minor burn. To soothe the pain, she puts the burned finger in her mouth. Withdrawing one’s hand to avoid injury and soothing the pain of that injury are two distinct evolutionary responses, but […]Continue Reading ...
Although paralysis is the most noticeable result of a spinal cord injury, a new study by researchers at The University of Texas at Austin suggests such injuries could throw off the internal clock of the entire body’s daily activities, from hormones to sleep-wake schedules. The spinal cord helps transfer information between the body and brain, […]Continue Reading ...
In the hours and days following a spinal cord injury, the gears that control the body’s internal clocks fall profoundly out of sync, impacting body temperature, hormone fluctuation, immunity and the timing of a host of other bodily processes, according to new University of Colorado Boulder research. The study, funded by the U.S. Department of […]Continue Reading ...
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